Deng, Lanqing; Chen, Lang; Zhu, Liangdi; Li, Yang; Ou-Yang, Jie; Wu, Shaofeng; Chen, Peng; Shen, Sheng; Guo, Junkang; Zhou, Yongbo; Au, Chak-Tong; Yin, Shuang-Feng published the artcile< Green, versatile, and scale-up synthesis of amides by aerobic oxidative amination over Ag2O/P-C3N4 photocatalyst>, Reference of 3959-07-7, the main research area is green versatile scale amide aerobic oxidative amination photocatalyst.
Being extensively applied in various fields of chem. and chem. industry, the development of a green and versatile method for the synthesis of amides is in line with the demand of sustainable chem. Herein, a direct, highly selective, and scale-up (5-20 mmol) method for photocatalytic synthesis of amides through aerobic oxidative amination of alcs. with amines was developed under visible light, room temperature, using air as the oxidant. Benefiting from the adsorption of sodium hemiaminal on catalyst lengthens the C-H bond (1.148 Å), this novel process is feasible for a broad range of functionlized amides (69 examples), especially those for drug manufacture (e.g., moclobemide and pipobroman). Imines was almost prevented with excellent amide selectivity up to 99% could be ascribed to the low energy barrier for hemiaminal dehydrogenation while that for dehydration is high (2.13 eV). This green and efficient protocol represents an ideal alternative to the currently known methods.
Chemical Engineering Science published new progress about Adsorption. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Reference of 3959-07-7.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary