《Optimization of an innovative vinylimidazole-based monolithic stationary phase and its use for pressured capillary electrochromatography》 was written by Murauer, Adele; Bakry, Rania; Partl, Gabriel; Huck, Christian W.; Ganzera, Markus. Electric Literature of C6H12Br2This research focused onvinylimidazole monolithic stationary phase pressured capillary electrochromatog; Caffeine; Capillary electrochromatography; Cationic monolith; Methylxanthines; Stationary phase optimization; Vinylimidazole. The article conveys some information:
A novel polymer monolith based on the dicationic crosslinker 3,3′-(hexane-1,6-diyl)bis(1-vinylimidazolium) bromide, the monomer 1-vinylimidazole and a ternary porogen mixture (1-propanol, decan-1-ol and water) was developed and optimized for capillary electrochromatog. This aim was accomplished by adjusting the composition of individual constituents in the polymerization mixture and monitored based on several relevant parameters (e.g. pore structure by SEM, generation of electroosmotic flow, or permeability of material). The ultimately selected composition yielded a monolithic phase which excellently resolved six methylxanthines (including caffeine, theobromine and theophylline) in 15 min. Key requirements concerning the used buffer were an acidic pH of 3 and the addition of 50% acetonitrile; addnl., a neg. voltage (-25 kV) had to be applied during analyses. The proposed separation mechanism was mixed mode, i.e. the combination of electrostatic repulsion and hydrophobic interaction. Monolith fabrication as well as separation efficiency are highly repeatable, the material was mech. stable and useable for at least 150 injections. Thus the presented stationary phase is definitely a very promising option for CEC. In the part of experimental materials, we found many familiar compounds, such as 1,6-Dibromohexane(cas: 629-03-8Electric Literature of C6H12Br2)
1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study redox switching behavior of single molecules; synthesis of water-soluble thermoresponsive polylactides.Electric Literature of C6H12Br2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary