Tian, Duanshuai; Xu, Ronghua; Zhu, Jinbin; Huang, Jianxun; Dong, Wei; Claverie, Jerome; Tang, Wenjun published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Asymmetric Hydroesterification of Diarylmethyl Carbinols》.Reference of 5-Bromobenzo[d][1,3]dioxole The article contains the following contents:
An efficient asym. hydroesterfication of diarylmethyl carbinols is developed for the first time with a Pd-WingPhos catalyst, resulting in a series of chiral 4-aryl-3,4-dihydrocoumarins in excellent enantioselectivities and good yields. The method features mild reaction conditions, a broad substrate scope, use of easily accessible starting materials, and low palladium loadings. A plausible stereochem. model is also proposed with the Pd-WingPhos catalyst. This method has enabled a 4-step asym. synthesis of (R)-tolterodine from readily available starting materials. In the experiment, the researchers used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Reference of 5-Bromobenzo[d][1,3]dioxole)
Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Reference of 5-Bromobenzo[d][1,3]dioxole
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary