In 2018,Miranda, Silvia; Gomez, Ana M.; Lopez, J. Cristobal published 《Diversity-Oriented Synthetic Endeavors of Newly Designed Ferrier and Ferrier-Nicholas Systems Derived from 1-C-Alkynyl-2-deoxy-2-C-Methylene Pyranosides》.European Journal of Organic Chemistry published the findings.Recommanded Product: Indium(III) bromide The information in the text is summarized as follows:
Novel pyranose derivatives that display Ferrier- and Ferrier-Nicholas-like reactivity have been designed. These systems: 1-C-alkynyl-2-deoxy-2-C-methylene pyranosides (Ferrier), and their corresponding dicobalthexacarbonyl alkenyl derivatives (Ferrier-Nicholas), which can be accessed by a concise synthetic route from com. available tri-O-acetyl-D-glucal, allow the incorporation of two nucleophiles (at positions C-3 and C-2′) in the pyranose ring. The study of these systems has resulted in the discovery of novel reaction patterns that allow, among others, access to open-chain derivatives, branched pyranosides, 1,6-anhydro derivatives and, when reacting with indole, access to a new family of tetracyclic indole-containing carbohydrate derivatives, namely, cyclohepta[b]indole-fused glycals. The latter are, most likely, formed by a bis Ferrier-type rearrangement followed by an unusual intramol. 7-endo-dig Friedel-Crafts alkenylation of one of the indole moieties by the C-1 alkyne.Indium(III) bromide(cas: 13465-09-3Recommanded Product: Indium(III) bromide) was used in this study.
Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Recommanded Product: Indium(III) bromide
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary