In 2018,Rao, Xiaofeng; Li, Naikai; Bai, Heng; Dai, Chaodi; Wang, Zheng; Tang, Wenjun published 《Efficient Synthesis of (-)-Corynoline by Enantioselective Palladium-Catalyzed α-Arylation with Sterically Hindered Substrates》.Angewandte Chemie, International Edition published the findings.Recommanded Product: 1-Bromo-2-isopropylbenzene The information in the text is summarized as follows:
Sterically hindered substrates can be employed in an enantioselective palladium-catalyzed α-arylation with the chiral monophosphorus ligand BI-DIME. This process enabled an efficient synthesis of the antidepressant (S)-nafenodone (I), a four-step enantioselective synthesis of the Sceletium alkaloid (+)-sceletium A-4 (II), a concise five-step enantioselective synthesis of (-)-corynoline (III), as well as a three-step preparation of (-)-DeN-corynoline (IV).1-Bromo-2-isopropylbenzene(cas: 7073-94-1Recommanded Product: 1-Bromo-2-isopropylbenzene) was used in this study.
1-Bromo-2-isopropylbenzene(cas: 7073-94-1) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool. Recommanded Product: 1-Bromo-2-isopropylbenzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary