Cao, Dawei; Yan, Chaoxian; Zhou, Panpan; Zeng, Huiying; Li, Chao-Jun published the artcile< Hydrogen bonding promoted simple and clean photo-induced reduction of C-X bond with isopropanol>, Recommanded Product: 2,4,6-Trimethylbromobenzene, the main research area is hydrogen bonding photoinduced reductive dehalogenation isopropanol.
We herein report a simple and clean photo-induced metal-free reduction of C-X bond under an atm. of air at room temperature Isopropanol is used as both the reducing reagent and solvent [e.g., Me 4-iodobenzoate → Me benzoate (96%) under UV irradiation in isopropanol]. Various functional groups (acids, esters, alcs., anilines, phenols, indoles, pyridines, cyano and trifluoromethyl groups) and other heterocyclic compounds are tolerated. Different organic halides (including C-I, C-Br and C-Cl bonds) can be dehalogenated with moderate to excellent yields. Polyhalides are also reduced chemoselectively and efficiently. DFT calculation suggests a six-membered ring transition state via C-X···H-O hydrogen bonding to decrease the activation energy.
Chemical Communications (Cambridge, United Kingdom) published new progress about Aryl halides Role: POL (Pollutant), RCT (Reactant), OCCU (Occurrence), RACT (Reactant or Reagent) (and heteroaryl halides and polyhalides). 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Recommanded Product: 2,4,6-Trimethylbromobenzene.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary