Zheng, Bingxiao; Xu, Jiao; Song, Jinliang; Wu, Haihong; Mei, Xuelei; Zhang, Kaili; Han, Wanying; Wu, Wei; He, Mingyuan; Han, Buxing published the artcile< Nanoparticles and single atoms of cobalt synergistically enabled low-temperature reductive amination of carbonyl compounds>, Category: bromides-buliding-blocks, the main research area is primary amine preparation; aldehyde ketone reductive amination cobalt catalyst.
Herein, authors designed several Co-based catalysts (denoted as Co@C-N(x), where x represents the pyrolysis temperature) by the pyrolysis of the metal-organic framework ZIF-67 at different temperatures Very interestingly, the prepared Co@C-N(800) could efficiently catalyze the reductive amination of various aldehydes/ketones to synthesize the corresponding primary amines with high yields at 35°C. Besides non-noble metal and mild temperature, the other unique advantage of the catalyst was that the substrates with different reduction-sensitive groups could be converted into primary amines selectively because the Co-based catalyst was not active for these groups at low temperature Systematic anal. revealed that the catalyst was composed of graphene encapsulated Co nanoparticles and atomically dispersed Co-Nx sites. The Co particles promoted the hydrogenation step, while the Co-Nx sites acted as acidic sites to activate the intermediate (Schiff base). The synergistic effect of metallic Co particles and Co-Nx sites is crucial for the excellent performance of the catalyst Co@C-N(800). To the best of knowledge, this is the first study on efficient synthesis of primary amines via reductive amination of carbonyl compounds over earth-abundant metal-based catalysts at low temperature (35°C).
Chemical Science published new progress about Aldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary