Su, Yingpeng; He, Haiyang; Zhao, Yanan; Li, Qinling; Feng, Yawei; Cao, Guiyan; Huang, Danfeng; Wang, Ke-Hu; Huo, Congde; Hu, Yulai published their research in Asian Journal of Organic Chemistry in 2021. The article was titled 《Sulfide-Catalyzed Diastereoselective Spirocyclopropanation: Constructing Spiro-cyclopropanyl-pyrazolones From α-Arylidenepyrazolones》.Category: bromides-buliding-blocks The article contains the following contents:
An efficient and diastereoselective [2+1] annulation of arylidenepyrazolones with bromides was developed that relies on in-situ formation of sulfur ylide via a direct sulfide-catalyzed process. A variety of spirocyclopropanyl pyrazolones were achieved in good to excellent yields (up to 93% yield) with high diastereoselectives (up to 20 : 1 dr). Meanwhile, several spirocyclopropanyl compounds were also prepared from corresponding enones. This catalytic strategy exhibited good functional group tolerance, gram-scale capacity and broad substrate scope and provided various spirocyclopropanyl derivativesBenzyl 2-bromoacetate(cas: 5437-45-6Category: bromides-buliding-blocks) was used in this study.
Benzyl 2-bromoacetate(cas: 5437-45-6) belongs to benzyl acetate. Benzyl acetate is a synthetic chemical produced for industry from benzyl alcohol and acetic acid, but is also naturally present in the essential oils of many plants, including jasmine and ylang ylang.Category: bromides-buliding-blocks
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary