Organic compounds having carbon bonded to bromine are called organic bromides. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C7H5BrO2.
Jayalakshmi, P. M.;SheebaJasmin, T. S.;Jose, Manu research published ã?Design, synthesis and antimycobacterial evaluation of 1,3,4-thiadiazole derivativesã? the research content is summarized as follows. In silico designing of 7 thiadiazole analogs (Z)-I (R1 = 2-OH, 3-NO2, 3-Br, 3-OMe-4-OH; R2 = OH, Cl, NO2) was carried out by using different software’s. They were subjected to wet lab synthesis and their structures were confirmed by FT-IR, NMR spectroscopy. Antimycobacterial activity of 7 analogs I was evaluated by MABA assay against Mycobacterium smegmatis. All the seven compounds are active against Mycobacterium smegmatis. Compounds I (R1 = 2-OH, R2 = NO2; R1 = 3-Br, R2 = NO2; R1 = 3-NO2, R2 = Cl; R1 = 2-OH, R2 = OH; R1 = 3-Br, R2 = OH) show activity at a concentration of 125μg/mL. Compounds I (R1 = 3-OMe-4-OH, R2 = NO2 (II); R1 = 3-Br, R2 = NO2 (III)) shows activity at a concentration of 250μg/mL. Both (II) and (III) show good docking score as well good activity in its in vitro studies, and were subjected to MTT assay for evaluating its cytotoxic potential. The LC50 value of (II) and (III) was found to be 152.347μg/mL and 226.287μg/mL resp. The (II) and (III) elicited high docking score shows moderate to good activity in its in vitro antimycobacterial evaluation and donot show any cytotoxic effect in the concentration range below MIC value obtained from MABA assay, whereas both of the compounds can be considered as a promising lead mol. for further research.
585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , Application of C7H5BrO2
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary