One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene, Name: 1-Bromo-3,5-dimethoxybenzene
Ma, Teng;Li, Xiao;Ping, Yuanyuan;Kong, Wangqing research published 《 Synthesis of gem-Difluoroalkenes via Ni-Catalyzed Three-Component Defluorinative Reductive Cross-Coupling of Organohalides, Alkenes and Trifluoromethyl Alkenes》, the research content is summarized as follows. Gem-Difluoroalkenes are considered ideal isosteres for metabolically susceptible carbonyl groups in modern drug discovery and medicinal chem. In addition, gem-difluoroalkenes are used as versatile precursors for the synthesis of difluoroalkylated compounds and monofluoroalkenes. Therefore, a great deal of effort has been devoted to developing efficient methods for their preparation The catalytic defluorinative functionalization of trifluoromethyl alkenes represents a useful strategy for the preparation of chiral gem-difluoroalkenes. However, most of these catalytic processes are still essentially limited to two-component defluorinative cross-couplings to form single C-C bonds. Due to the challenge of controlling chemoselectivity in the carbon-carbon bond forming events, three-component defluorinative cross-coupling involving multiple C-C bond formations has rarely been studied. Authors report a nickel-catalyzed three-component defluorinative reductive cross-coupling of organohalides, alkenes and trifluoromethyl alkenes. A variety of electron-rich and electron-deficient alkenes, as well as aryl and alkyl halides can efficiently participate in the formation of three-component cross-coupling products. This reaction proceeds under mild conditions and exhibits excellent functional group compatibility without requiring a pendant chelating group, providing a variety of functionalized gem-difluoroalkenes in good yields with excellent chemoselectivity.
Name: 1-Bromo-3,5-dimethoxybenzene, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary