Organic compounds having carbon bonded to bromine are called organic bromides. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application of C7H15Br.
Mach, Mateusz;Bazydlo-Guzenda, Katarzyna;Buda, Pawel;Matloka, Mikolaj;Dzida, Radoslaw;Stelmach, Filip;Galazka, Kinga;Wasinska-Kalwa, Malgorzata;Smuga, Damian;Holowinska, Dagmara;Dawid, Urszula;Gurba-Bryskiewicz, Lidia;Wisniewski, Krzysztof;Dubiel, Krzysztof;Pieczykolan, Jerzy;Wieczorek, Maciej research published 《 Discovery and development of CPL207280 as new GPR40/FFA1 agonist》, the research content is summarized as follows. Due to a unique mechanism that limits the possibility of hypoglycemia, the free fatty acid receptor (FFA1) is an attractive target for the treatment of type 2 diabetes. So far, however, none of the promising agonists have been able to enter the market. The most advanced clin. candidate, TAK-875, was withdrawn from phase III clin. trials due to liver safety issues. In this article, we describe the key aspects leading to the discovery of CPL207280 (13), the design of which focused on long-term safety. The introduction of small, nature-inspired acyclic structural fragments resulted in compounds with retained high potency and a satisfactory pharmacokinetic profile. Optimized synthesis and upscaling provided a stable, solid form of CPL207280-51 (45) with the properties required for the toxicol. studies and ongoing clin. trials.
629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Application of C7H15Br
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary