Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Organic compounds having carbon bonded to bromine are called organic bromides. Recommanded Product: 1-Bromo-3-(bromomethyl)benzene.
Mariki, Ali akbar;Anaeigoudari, Akbar;Zahedifar, Mahboobeh;Pouramiri, Behjat;Ayati, Adileh;Lotfi, Safa research published 《 Design, Green Synthesis, and Biological Evaluation of New Substituted Tetrahydropyrimidine Derivatives as Acetylcholinesterase Inhibitors》, the research content is summarized as follows. A series of novel tetrahydropyrimidin-4-yl pyridine derivatives I (Ar = Bn, 2-chlorobenzyl, 2,4-dimethylbenzyl, etc.) have been designed and synthesized as inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). The in vitro studies showed that all the synthesized derivatives I showed significant BChE inhibitory activity more potent than donepezil as the standard (IC50 values less than 0.1 μM). All the target compounds I demonstrated good AChE inhibitory effects comparable with donepezil as the reference drug with IC50 values ranging from 0.08 to 0.1 μM. The best results were obtained by 4-Me substituted derivative I (Ar = 4-Me benzyl) with IC50 value of 0.082 μM which was comparable with AChE inhibitory effects of donepezil (IC50 = 0.079 μM).
823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.
3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.
3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Recommanded Product: 1-Bromo-3-(bromomethyl)benzene
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary