Author: Jessica.F

Xu, Feng published the artcileDeveloping versatile and highly selective chemosensor for amines detection based on bis-thiophene methane containing cyclopalladated compounds, Recommanded Product: 1-Bromooctane, the publication is Sensors and Actuators, B: Chemical (2022), 131561, database is CAplus.

Cyclopalladated compounds (CPCs) have special properties due to its internal multiple conjugate planes in their structure. Herein, a series of bis-thiophene methane-pyridine-Schiff base derivatives (L_n) and their CPCs (L_n-Pd) as monomers were prepared All cyclopalladated monomers showed extreme sensitivity to organic amines in both solution and vapor states. The results of structural anal. manifested that the complexes before and after alkali-treated have a relationship between monomer and dimer. Furthermore, the base-induced mechanism was expounded. To take full advantage of this feature, we utilized the monomer containing tetraphenylethylene (L₄-Pd) to detect organic amines in solution, which showed excellent sensitivity toward triethylamine and diethylamine with the limit of detection of 41 nM and 104 nM, resp. Then, the L₄-Pd coated labels were exposed to amine vapors at ppm level, which showed visible color variation in n-butylamine, ethylenediamine, diethylamine, and cyclohexylamine atm. It is suggesting that the materials have potential applications to detect organic amines in solution at trace anal. and a solid colorimetric chemosensor for organic amine vapors.

Sensors and Actuators, B: Chemical published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H10S, Recommanded Product: 1-Bromooctane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Peng, Kai published the artcileNovel synthesis of poly(3,4-dinitro-thiophen-2-yl arylamine) derivatives via facile C-Br/N-H bulk polycondensation and its application of thermalsensor, Product Details of C4Br2N2O4S, the publication is Polymer (2020), 122550, database is CAplus.

C-Br/N-H bulk polycondensation is firstly proposed and corresponding poly(3,4-dinitro-thiophen-2-yl arylamine)s derivatives have been successfully obtained with quant. yield. Typical crystal anal. reveals that its effective reaction points distance (RPD, distance between Br and H atom) is 5.083 Å, which is 66.7% longer than the sum of van der Waals radius (r_w) of bromine and hydrogen atoms (3.05 Å). Carbazole-based monomer was explored as a thermalsensor with excellent relative sensitivity (S_a) of 0.45% K^-1.

Polymer published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Product Details of C4Br2N2O4S.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gu, Jilong published the artcileAnhydrous proton conduction in protic ionic liquid crystals formed by 1-alkyl-3H-imidazolium hydrogen sulfates, Related Products of bromides-buliding-blocks, the publication is Ionics (2022), 28(5), 2293-2300, database is CAplus.

Dynamic self-assembly of liquid crystals favors the formation of hydrogen bond networks essential for anhydrous proton conduction. To endow liquid crystals with inherently exchangeable protons for proton conduction, protic 1-alkyl-3H-imidazolium hydrogen sulfates ([C_nIm][HSO₄]) with different lengths of alkyl chains are synthesized. Interdigitated smectic A_d (S_Ad) liquid crystal phases are observed for [C_nIm][HSO₄], in which the protic ionic pairs aggregate into lamellas. Electrochem. characterization reveals that the anhydrous proton conductivity of [C_nIm][HSO₄] reaches up to 5.3 mS cm^-1 in the S_Ad phase. The single fuel cells fabricated from the [C_nIm][HSO₄]@PVDF supported membranes exhibit a peak power d. of 2.6 mW cm^-2 at 130 °C under non-humidified conditions. It was the enriched lamellar hydrogen bond networks formed by the protic ionic pairs that contribute to the anhydrous proton conduction. The protic ionic liquid crystals possess a great potential to construct electrochem. devices involving anhydrous proton conduction.

Ionics published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Chen, Yi-Sheng published the artcileNew Exciplex-Forming Co-Host System and Thienothiadazole-based Fluorescent Emitter for High-Efficiency and Promising Stability Near-Infrared OLED, Recommanded Product: 2,5-Dibromo-3,4-dinitrothiophene, the publication is Advanced Optical Materials (2022), 10(4), 2101952, database is CAplus.

Two new spirobifluorene (SF)-centered donors (D) DPSF and DTSF are developed to blend with acceptor (A) CN-T2T for exciplex formation. The transient photoluminescence characterizations of pristine donor and D:A blended films verify the donor aggregates emissions that lead to relatively low photoluminescence quantum yield (PLQY) of exciplex emission. However, the charge recombination at lower energy exciplex state leads the device with DPSF:CN-T2T blend to give electroluminescence (EL) λ_max of 584 nm and external quantum efficiency (EQE) of 6.0%. The DPSF:CN-T2T exciplex excitons are efficiently extracted by a D-A-D-type fluorescence emitter TTDSF comprising thienothiadiazole core and SF peripherals via Forster energy transfer to give near-IR (NIR) emission (760 nm, PLQY 26%). After the electron-transporting layer thickness optimization, the device with DPSF:CN-T2T: 7 weight% TTDSF as emitting layer affords EL λmax 774 nm and EQE up to 5.3%, one of the best cases in NIR organic light-emitting diodes (OLEDs). More importantly, the device stability has been examined to display an excellent lifetime (LT95 > 200 h). This work manifests the judicious combination of an exciplex-forming co-host system and a designated NIR emitter equipping with a high quinoidal core and rigid peripheral SF groups that can realize an efficient NIR OLED.

Advanced Optical Materials published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Recommanded Product: 2,5-Dibromo-3,4-dinitrothiophene.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gao, Xiu-zheng published the artcileDesign, synthesis and in vitro anticancer research of novel tetrandrine and fangchinoline derivatives, Related Products of bromides-buliding-blocks, the publication is Bioorganic Chemistry (2021), 104694, database is CAplus and MEDLINE.

Cancer treatment is one of the major public health issues in the world. Tetrandrine (Tet) and fangchinoline (d-Tet) are two bis-benzyl isoquinoline alkaloids extracted from Stephania tetrandra S. Moore, and their antitumor activities have been confirmed. However, the ED of Tet and d-Tet were much higher than that of the pos. control and failed to meet clin. standards Therefore, in this study, as a continuation of our previous work to study and develop high-efficiency and low-toxic antitumor lead compounds, twenty new Tet and d-Tet derivatives were designed, synthesized and evaluated as antitumor agents against six cancer cell lines (H460, H520, HeLa, HepG-2, MCF-7, SW480 cell lines) and BEAS-2B normal cells by CCK-8 anal. Ten derivatives showed better cytotoxic effects than the parent fangchinoline, of which I showed the strongest cell growth inhibitory activity with an IC₅₀ value of 0.59μM against A549 cells. Subsequently, the antitumor mechanism of I was studied by flow cytometry, Hoechst 33258, JC-1 staining, cell scratch, transwell migration, and Western blotting assays. These results showed that compound I could inhibit A549 cell proliferation by arresting the G2/M cell cycle and inhibiting cell migration and invasion by reducing MMP-2 and MMP-9 expression. Meanwhile, I could induce apoptosis of A549 cells through the intrinsic pathway regulated by mitochondria. In addition, compound I inhibited the phosphorylation of PI3K, Akt and mTOR, suggesting a correlation between blocking the PI3K/Akt/mTOR pathway and the above antitumor activities. These results suggest that compound I may be a future drug for the development of new potential drug candidates against lung cancer.

Bioorganic Chemistry published new progress about 21101-63-3. 21101-63-3 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,sulfides,Benzyl bromide,Benzene, name is (4-(Bromomethyl)phenyl)(trifluoromethyl)sulfane, and the molecular formula is C8H6BrF3S, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Lin, Hang published the artcileOrganic dyads and triads based on the triphenylene-rylenediimide couple: Molecular design, self-organization, and photo-physical properties, Synthetic Route of 111-83-1, the publication is Dyes and Pigments (2022), 109911, database is CAplus.

Liquid-crystalline D-A dyads and A-D-A triads, based on the chem. association of electron-donor (D) triphenylene discogens and electron-acceptor (A) perylene/benzoperylene diimides, have been synthesized by the Pd-catalyzed Sonogashira coupling/DBU-promoted cyclization reactions tandem. These mol. heterojunctions spontaneously self-organize into columnar hexagonal (Col_hex) or/and rectangular (Col_rec) mesophases, over broad temperature ranges including room temperature, with the antagonist moieties segregated into alternated homo-mol. (homolithic) stacks within mixed columns. Their intramol. electron and energy transfers have been studied by UV/Vis absorption and fluorescence emission spectroscopies. Due to photo-induced electron transfer between donor and acceptor units, fluorescence quenching is systematically observed for all the dyads and triads. This study further reveals that perylenediimide is a stronger electron acceptor than the larger benzoperylenediimide building block. D. function theory calculations of their mol. structures and HOMO-LUMO energy levels and gaps support the exptl. results and demonstrate that these donor-acceptor systems have potential applications in various optoelectronic devices.

Dyes and Pigments published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Synthetic Route of 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Chan-Seng, Delphine published the artcilePrimary Structure Control of Oligomers Based on Natural and Synthetic Building Blocks, Related Products of bromides-buliding-blocks, the publication is ACS Macro Letters (2014), 3(3), 291-294, database is CAplus and MEDLINE.

Solid-phase synthesis was exploited for the preparation of oligomers constructed from natural and synthetic building blocks by combining the formation of amide bonds and copper-assisted alkyne-azide cycloaddition reactions extending the variety of oligomers with well-defined primary structures accessible through this technique and providing control over the spacing between amino acids.

ACS Macro Letters published new progress about 56970-78-6. 56970-78-6 belongs to bromides-buliding-blocks, auxiliary class Bromide,Carboxylic acid,Aliphatic hydrocarbon chain,Inhibitor, name is 3-Bromo-2-methylpropanoic acid, and the molecular formula is C4H7BrO2, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhao, Yin-Na published the artcileA new approach to access difluoroalkylated diarylmethanes via visible-light photocatalytic cross-coupling reactions, Recommanded Product: Ethylbromofluoroacetate, the publication is Chemical Communications (Cambridge, United Kingdom) (2018), 54(32), 3993-3996, database is CAplus and MEDLINE.

Difluoroalkylated diarylmethanes with biol. and pharmacol. potentials were synthesized from para-quinone methides (p-QMs) and difluoroalkylating reagents via a visible light photocatalysis strategy. Mechanism studies showed that the excited photocatalyst, *fac-Ir(ppy)₃, was primarily quenched by p-QMs and the generated diarylmethane radical intermediates then underwent a radical-radical cross-coupling reaction with difluoroalkyl radicals. This reaction features mild conditions, high efficiency and wide functional group compatibility.

Chemical Communications (Cambridge, United Kingdom) published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C7H6Cl2O, Recommanded Product: Ethylbromofluoroacetate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Yuqiang published the artcileReaction scope and mechanistic insights of nickel-catalyzed migratory Suzuki-Miyaura cross-coupling, Formula: C9H8BrF3, the publication is Nature Communications (2020), 11(1), 417, database is CAplus and MEDLINE.

In this work, a Ni-catalyzed migratory Suzuki-Miyaura cross-coupling featuring high benzylic or allylic selectivity has been developed. With this method, unactivated alkyl electrophiles and aryl or vinyl boronic acids can be efficiently transferred to diarylalkane or allylbenzene derivatives under mild conditions. Importantly, unactivated alkyl chlorides can also be successfully used as the coupling partners. To demonstrate the applicability of this method, showcase that this strategy can serve as a platform for the synthesis of terminal, partially deuterium-labeled mols. from readily accessible starting materials. Exptl. studies suggest that migratory cross-coupling products are generated from Ni(0/II) catalytic cycle. Theor. calculations indicate that the chain-walking occurs at a neutral nickel complex rather than a cationic one. In addition, the original-site cross-coupling products can be obtained by alternating the ligand, wherein the formation of the products has been rationalized by a radical chain process.

Nature Communications published new progress about 1997-80-4. 1997-80-4 belongs to bromides-buliding-blocks, auxiliary class Trifluoromethyl,Fluoride,Bromide,Benzene, name is 1-(2-Bromoethyl)-3-(trifluoromethyl)benzene, and the molecular formula is C9H8BrF3, Formula: C9H8BrF3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary