Author: Jessica.F

Organic compounds having carbon bonded to bromine are called organic bromides. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Electric Literature of 20469-65-2.

Vuk, Dragana;Radovanovic-Peric, Floren;Mandic, Vilko;Lovrincevic, Vilma;Rath, Thomas;Panzic, Ivana;Le-Cunff, Jerome research published 《 Synthesis and Nanoarchitectonics of Novel Squaraine Derivatives for Organic Photovoltaic Devices》, the research content is summarized as follows. Necessary advancements in the area of organic photovoltaic (OPV) devices include the upgrade of power conversion efficiencies (PCE) and stability. One answer to these demands lies in the research into new absorbers. Here, we focus on the development of new small mol. absorbers from the group of squaraines (SQs). These modular absorbers can be applied as donors in organic solar cells and have the ability to utilize a broad range of solar radiation if blended with suitable acceptors. In order to allow for the compatibility and favorable organization of donor and acceptor in the absorber layer, we intend to optimize the structure of the SQ by varying the groups attached to the squaric acid core. For that purpose, we accordingly developed a well-suited synthesis route. The novel alkyl- and benzyl-substituted aryl aminosquaraines were synthesized through an improved and eco-friendly procedure. Special emphasis was placed on optimizing the amination reaction to obtain initial precursors in the synthesis of squaraine, avoiding hitherto common catalytic processes. All SQ precursors and SQ products were completely described. The derived SQs were addnl. characterized in thin-film configuration using cyclic voltammetry and UV-VIS spectroscopy and then processed to prepare self-standing bulk heterojunction (BHJ) thin films in conjunction with fullerene-based electron acceptors, which were characterized via profilometry. The comparison between SQ and BHJ solutions and thin films, using at. force microscopy and UV-VIS spectroscopy, revealed differences in susceptibility for the organization and orientation of the constituting domains.

20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., Electric Literature of 20469-65-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, Application of C6H11BrO2

Volpato, Giulia Alice;Colusso, Elena;Paoloni, Lorenzo;Forchetta, Mattia;Sgarbossa, Francesco;Cristino, Vito;Lunardon, Marco;Berardi, Serena;Caramori, Stefano;Agnoli, Stefano;Sabuzi, Federica;Umari, Paolo;Martucci, Alessandro;Galloni, Pierluca;Sartorel, Andrea research published 《 Artificial photosynthesis: photoanodes based on polyquinoid dyes onto mesoporous tin oxide surface》, the research content is summarized as follows. Dye-sensitized photoelectrochem. cells represent an appealing solution for artificial photosynthesis, aimed at the conversion of solar light into fuels or commodity chems. Extensive efforts have been directed towards the development of photoelectrodes combining semiconductor materials and organic dyes; the use of mol. components allows to tune the absorption and redox properties of the material. Recently, we have reported the use of a class of pentacyclic quinoid organic dyes (KuQuinone) chemisorbed onto semiconducting tin oxide as photoanodes for water oxidation In this work, we investigate the effect of the SnO₂ semiconductor thickness and morphol. and of the dye-anchoring group on the photoelectrochem. performance of the electrodes. The optimized materials are mesoporous SnO₂ layers with 2.5 μm film thickness combined with a KuQuinone dye with a 3-carboxylpropyl-anchoring chain: these electrodes achieve light-harvesting efficiency of 93% at the maximum absorption wavelength of 533 nm, and photocurrent d. J up to 350 μA/cm² in the photoelectrochem. oxidation of ascorbate, although with a limited incident photon-to-current efficiency of 0.075%. Calculations based on the d. functional theory (DFT) support the role of the reduced species of the KuQuinone dye via a proton-coupled electron transfer as the competent species involved in the electron transfer to the tin oxide semiconductor. Finally, a preliminary investigation of the photoelectrodes towards benzyl alc. oxidation is presented, achieving photocurrent d. up to 90 μA/cm² in acetonitrile in the presence of N-hydroxysuccinimide and pyridine as redox mediator and base, resp. These results support the possibility of using mol.-based materials in synthetic photoelectrochem.

Application of C6H11BrO2, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. HPLC of Formula: 585-76-2.

Vishwanath, Divakar;Girimanchanaika, Swamy S.;Dukanya, Dukanya;Rangappa, Shobith;Yang, Ji-Rui;Pandey, Vijay;Lobie, Peter E.;Basappa, Basappa research published 《 Design and Activity of Novel Oxadiazole Based Compounds That Target Poly(ADP-ribose) Polymerase》, the research content is summarized as follows. Novel PARP inhibitors with selective mode-of-action have been approved for clin. use. Herein, oxadiazole based ligands that are predicted to target PARP-1 have been synthesized and screened for the loss of cell viability in mammary carcinoma cells, wherein seven compounds were observed to possess significant IC₅₀ values in the range of 1.4 to 25 μM. Furthermore, compound 5u, inhibited the viability of MCF-7 cells with an IC₅₀ value of 1.4μM, when compared to Olaparib (IC₅₀ = 3.2 μM). Compound 5s also decreased cell viability in MCF-7 and MDA-MB-231 cells with IC₅₀ values of 15.3 and 19.2 μM, resp. Treatment of MCF-7 cells with compounds 5u and 5s produced PARP cleavage, H2AX phosphorylation and CASPASE-3 activation comparable to that observed with Olaparib. Compounds 5u and 5s also decreased foci-formation and 3D Matrigel growth of MCF-7 cells equivalent to or greater than that observed with Olaparib. Finally, in silico anal. demonstrated binding of compound 5s towardsthe catalytic site of PARP-1, indicating that these novel oxadiazoles synthesized herein may serve as exemplars for the development of new therapeutics in cancer.

HPLC of Formula: 585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 19111-87-6, formula is C18H11Br, Name is 2-Bromotriphenylene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: 2-Bromotriphenylene.

Vijaykumar, Bodduri Venkata Durga;Nalluri, Sanjeevkumar;Uppada, Mahesh Kumar;Sen, Saikat;Ulla, Hidayath;Krishnamanohara;Kamaja, Chaitanya Krishna;Balakrishnan, Muralidharan;Katiyar, Monica;Oruganti, Srinivas research published 《 Ligand-Free Suzuki Coupling for the Practical Synthesis of 4-(Triphenylen-2-yl) dibenzothiophene for Solution-Processed OLEDs》, the research content is summarized as follows. A practical and efficient synthesis of 4-(triphenylen-2-yl)dibenzothiophene, a phosphorescent host, has been established via ligand-free palladium on carbon (Pd/C) catalyst mediated Suzuki coupling reaction. The process allowed us to recover and reuse the heterogeneous Pd/C catalyst for cost-effectiveness with a conversion yield greater than 90%. Moreover, interesting results on solid-state studies of the sublimed title material have been captured along with its photo-phys. and electrochem. properties, which are appropriate for its use as a host material. Finally, we have fabricated solution-processed organic light-emitting diodes (OLEDs) by using the title material as a host and bis(4-phenylthieno[3,2-c]pyridinato-N,C2 ‘) (acetylacetonate) iridium(III) (PO-01), as a phosphorescent dopant. The devices exhibited efficiencies of ∼9 cd/A at 1000 cd/m², and the results were comparable with the traditional host, 4,4 ‘-bis(N-carbazolyl)-1,1 ‘-biphenyl (CBP).

19111-87-6, 2-Bromotriphenylene is a useful research compound. Its molecular formula is C18H11Br and its molecular weight is 307.2 g/mol. The purity is usually 95%.
2-Bromotriphenylene is a brominating agent that has the ability to react with sodium carbonate and emit light. The luminescence of 2-bromotriphenylene can be used as an indicator of the degree of dilution, or how much water is present in a solution. It also emits light when it reacts with chloride ions in a reaction solution. 2-Bromotriphenylene can be used as a polymer matrix to form polymeric films, which are then used as catalysts for organic reactions. The luminescence properties of 2-bromotriphenylene make it suitable for use in functional theory experiments. This chemical compound is relatively low cost, and has been shown to have high yield in catalysis., Recommanded Product: 2-Bromotriphenylene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Category: bromides-buliding-blocks.

Vessally, Esmail;Monfared, Aazam;Eskandari, Zahra;Abdoli, Morteza;Hosseinian, Akram research published 《 A new strategy for the synthesis of 2-mercaptobenzazole derivatives by green chemistry metrics》, the research content is summarized as follows. A green and efficient method was developed for the synthesis of 2-mercaptobenzazole derivatives via the reaction of com. available aniline derivatives with low-cost and nontoxic potassium thiocyanate in water. The reactions proceeded smoothly under catalyst- and ligand-free conditions to give the corresponding products in good to excellent yields. The versatility, low cost, and environmental friendliness, in combination with high yields and easy work-up makes the procedure noteworthy.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Synthetic Route of 629-04-9.

Verma, Suryadev K.;Punji, Benudhar research published 《 Manganese-Catalyzed C(sp²)-H Alkylation of Indolines and Arenes with Unactivated Alkyl Bromides》, the research content is summarized as follows. Selective C(sp²)-H bond alkylation of indoline like 2,3-dihydro-1-(2-pyridinyl)-1H-indole, carbazole like 9-(2-pyridinyl)-9H-carbazole and (2-pyridinyl)arenes I (R¹ = H, 4-Me, 4-OMe, 3-F₃C) with unactivated alkyl bromides R²(CH₂)₂Br (R² = Et, Pr, 4-(9H-carbazol-9-yl)butyl, etc.) is achieved using MnBr₂ catalyst in the absence of an external ligand. The alkylation uses a simple LiHMDS base and avoids the necessity of Grignard reagent, unlike other Mn-catalyzed C-H functionalization. This reaction proceeded either through a five- or less-favored six-membered metallacycle, and tolerated diverse functionalities, including alkenyl, alkynyl, silyl, aryl ether, pyrrolyl, indolyl, carbazolyl and alkyl bearing fatty alc. and polycyclic-steroid moieties. Alkylation follows a single electron transfer (SET) pathway involving 1e oxidative addition of alkyl bromide and rate-limiting C-H metalation.

629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., Synthetic Route of 629-04-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine, Category: bromides-buliding-blocks

Verma, Shruti;Kujur, Shelly;Sharma, Richa;Pathak, Devendra D. research published 《 Cucurbit[6]uril-Supported Fe₃O₄ Magnetic Nanoparticles Catalyzed Green and Sustainable Synthesis of 2-Substituted Benzimidazoles via Acceptorless Dehydrogenative Coupling》, the research content is summarized as follows. A new composite, cucurbit[6]uril (CB[6])-supported magnetic nanoparticles, Fe₃O₄-CB[6], was synthesized via a co-precipitation method in air and fully characterized by Fourier transform IR spectroscopy, powder X-ray diffraction, XPS, field-emission SEM, high-resolution transmission electron microscopy, energy-dispersive X-ray spectroscopy, thermogravimetric anal., inductively coupled plasma-mass spectrometry, and vibrating sample magnetometry techniques. It has been found to be a highly efficient, economic, and sustainable heterogeneous catalyst and has been employed for the first time for the synthesis of a series of biol. important 2-substituted benzimidazoles from various benzyl alcs. and 1,2-diaminobenzenes under solvent-free conditions via acceptorless dehydrogenative coupling to afford the corresponding products in good to excellent yields (68-94%). The magnetic nature of the nanocomposite facilitates the facile recovery of the catalyst from the reaction mixture by an external magnet. The catalyst can be reused up to five times with negligible loss in its catalytic activity. All the isolated products were characterized by ¹H and ¹³C{¹H} NMR spectroscopy.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane, HPLC of Formula: 629-04-9

Vereshchagin, A. N.;Minaeva, A. P.;Egorov, M. P. research published 《 Synthesis and antibacterial activity of new tetrakisquaternary ammonium compounds based on pentaerythritol and 3-hydroxypyridine》, the research content is summarized as follows. Tetrakisquaternary ammonium compounds based on pentaerythritol I (n = 7, 8, 9, 10, 11, 12) were synthesized for the first time. Bacteriostatic effect of the obtained compounds I was evaluated towards opportunistic gram-pos. Methicillin-resistant Staphylococcus aureus (strain ATCC 25923), gram-neg. Escherichia coli (ATCC 25922), and Pseudomonas aeruginosa (ATCC 27853). The activity of reported salts I was evaluated competitively with that of known antiseptics, Octenidine Dihydrochloride and Chlorhexidine Digluconate. The effect of length of the alkyl substituent in the salts I on their biol. activity was established. These new compounds I are based on available pentaerythritol and 3-hydroxypyridine.

HPLC of Formula: 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid, Product Details of C7H5BrO2

Verdirosa, Federica;Gavara, Laurent;Sevaille, Laurent;Tassone, Giusy;Corsica, Giuseppina;Legru, Alice;Feller, Georges;Chelini, Giulia;Mercuri, Paola Sandra;Tanfoni, Silvia;Sannio, Filomena;Benvenuti, Manuela;Cerboni, Giulia;De Luca, Filomena;Bouajila, Ezeddine;Vo Hoang, Yen;Licznar-Fajardo, Patricia;Galleni, Moreno;Pozzi, Cecilia;Mangani, Stefano;Docquier, Jean-Denis;Hernandez, Jean-Francois research published 《 1,2,4-Triazole-3-Thione Analogues with a 2-Ethylbenzoic Acid at Position 4 as VIM-type Metallo-β-Lactamase Inhibitors》, the research content is summarized as follows. Metallo-β-lactamases (MBLs) are increasingly involved as a major mechanism of resistance to carbapenems in relevant opportunistic Gram-neg. pathogens. Unfortunately, clin. efficient MBL inhibitors still represent an unmet medical need. We previously reported several series of compounds based on the 1,2,4-triazole-3-thione scaffold. In particular, Schiff bases formed between diversely 5-substituted-4-amino compounds and 2-carboxybenzaldehyde were broad-spectrum inhibitors of VIM-type, NDM-1 and IMP-1 MBLs. Unfortunately, these compounds were unable to restore antibiotic susceptibility of MBL-producing bacteria, probably because of poor penetration and/or susceptibility to hydrolysis. To improve their microbiol. activity, we synthesized and characterized compounds where the hydrazone-like bond of the Schiff base analogs was replaced by a stable Et link. This small change resulted in a narrower inhibition spectrum, as all compounds were poorly or not inhibiting NDM-1 and IMP-1, but showed a significantly better activity on VIM-type enzymes, with Ki values in the μM to sub-μM range. The resolution of the crystallog. structure of VIM-2 in complex with one of the best inhibitors yielded valuable information about their binding mode. Interestingly, several compounds were shown to restore the β-lactam susceptibility of VIM-type-producing E. coli laboratory strains and also of K. pneumoniae clin. isolates. In addition, selected compounds were found to be devoid of toxicity toward human cancer cells at high concentration, thus showing promising safety.

Product Details of C7H5BrO2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid, Recommanded Product: 3-Bromobenzoic acid

Venteicher, Brooklynn;Merklin, Kasey;Ngo, Huy X.;Chien, Huan-Chieh;Hutchinson, Keino;Campbell, Jerome;Way, Hannah;Griffith, Joseph;Alvarado, Cesar;Chandra, Surabhi;Hill, Evan;Schlessinger, Avner;Thomas, Allen A. research published 《 The effects of prodrug size and a carbonyl linker on L-type amino acid transporter 1-targeted cellular and brain uptake》, the research content is summarized as follows. The L-type amino acid transporter 1 (LAT1, SLC7A5) imports dietary amino acids and amino acid drugs (e. g., L-DOPA) into the brain, and plays a role in cancer metabolism Though there have been numerous reports of LAT1-targeted amino acid-drug conjugates (prodrugs), identifying the structural determinants to enhance substrate activity has been challenging. In this work, we investigated the position and orientation of a carbonyl group in linking hydrophobic moieties including the anti-inflammatory drug ketoprofen to L-tyrosine and L-phenylalanine. We found that esters of meta-carboxyl L-phenylalanine had better LAT1 transport rates than the corresponding acylated L-tyrosine analogs. However, as the size of the hydrophobic moiety increased, we observed a decrease in LAT1 transport rate with a concomitant increase in potency of inhibition. Our results have important implications for designing amino acid prodrugs that target LAT1 at the blood-brain barrier or on cancer cells.

Recommanded Product: 3-Bromobenzoic acid, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary