Author: Jessica.F

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Recommanded Product: Ethyl 3-bromo-2-oxopropanoate.

Sheikholeslami-Farahani, Fatemeh;Sadeghi Marasht, Abdollah;Mirabi, Ali;Ghazvini, Maryam;Hosseinnasab Rostam, Mohammad research published 《 Ionic Liquid as Green and Recyclable Solvent for the Synthesis of Pyrazinoquinazolines: Study of Antioxidant Activity》, the research content is summarized as follows. The preparation of pyrazinoquinazoline derivatives was performed in high yields by four component reactions of isoquinolin-3-ylmethanamine, α-haloketones, activated acetylenic compounds and Et bromoacetate in ionic liquid as green media at room temperature In addition, due to having quinazoline core in the synthesized compounds, evaluation of antioxidant activity was performed by radical trapping by DPPH and reducing power of ferric ion experiments As a result, synthesized compounds showed low radical trapping by DPPH and good reducing ability of ferric ion. The current procedure has the benefits for instance excellent yield of reaction, green media and easy separation of product.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Recommanded Product: Ethyl 3-bromo-2-oxopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 2576-47-8, formula is C2H7Br2N, The most pervasive is the naturally produced bromomethane. Safety of 2-Bromoethylamine hydrobromide

Shcherbakov, Dmitriy;Baev, Dmitriy;Kalinin, Mikhail;Dalinger, Alexander;Chirkova, Varvara;Belenkaya, Svetlana;Khvostov, Aleksei;Krut’ko, Dmitry;Medved’ko, Aleksei;Volosnikova, Ekaterina;Sharlaeva, Elena;Shanshin, Daniil;Tolstikova, Tatyana;Yarovaya, Olga;Maksyutov, Rinat;Salakhutdinov, Nariman;Vatsadze, Sergey research published 《 Design and Evaluation of Bispidine-Based SARS-CoV-2 Main Protease Inhibitors》, the research content is summarized as follows. For the first time, derivatives of 3,7-diazabicyclo[3.3.1]nonane (bispidine) were proposed as potential inhibitors of the SARS-CoV-2 main viral protease (3-chymotrypsin-like, 3CLpro). Based on the created pharmacophore model of the active site of the protease, a group of compounds were modeled and tested for activity against 3CLpro. The 3CLpro activity was measured using the fluorogenic substrate Dabcyl-VNSTLQSGLRK(FAM)MA; the efficiency of the proposed approach was confirmed by comparison with literature data for ebselen and disulfiram. The results of the experiments performed with bispidine compounds showed that 14 compounds exhibited activity in the concentration range 1-10μM, and 3 samples exhibited submicromolar activity. The structure-activity relationship studies showed that the mols. containing a carbonyl group in the ninth position of the bicycle exhibited the maximum activity. Based on the exptl. and theor. results obtained, further directions for the development of this topic were proposed.

2576-47-8, 2-Bromoethylamine hydrobromide is a useful building block for proteomics research.
2-Bromoethylamine hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist. It is used to construct C2-symmetric imidazolidinylidene ligands with a dioxolane backbone.
2-Bromoethylamine Hydrobromide is used in the synthesis of analogs of 5,​10,​15,​20-​tetrakis(1-​methylpyridinium-​4-​yl)​porphyrin (TMPyP4) as inhibitors of human telomerase. It is also used to prepare SB-705498, a potent, selective and orally bioavailable TRPV1 antagonist.
2-Bromoethylamine hydrobromide is a nonsteroidal anti-inflammatory drug that is used to treat inflammation and pain. It is a prodrug that is hydrolyzed in vivo to its active form, 2-Bromoethylamine hydrobromide. The bound form of this drug has been shown to inhibit the development of cell nuclei in the nucleus of cells. This drug also inhibits the production of nitric oxide, which leads to cell death by necrosis. 2-Bromoethylamine hydrobromide has been shown to have an inhibitory effect on the activity of glycol ethers, which are used as solvents for resins in coatings and adhesives., Safety of 2-Bromoethylamine hydrobromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Synthetic Route of 629-04-9.

Sharma, Neha;Gupta, Monika;Chowhan, Bushra;Frontera, Antonio research published 《 Magnetically separable nanocatalyst (IL@CuFe₂O₄-L-Tyr-TiO₂/TiTCIL): Preparation, characterization and its applications in 1,2,3-triazole synthesis and in photodegradation of MB》, the research content is summarized as follows. The present work encompasses the synthesis of novel heterogeneous magnetic nanocatalyst(IL@CuFe₂O₄-L-Tyr-TiO₂/TiTCIL) and its characterization by Fourier-transform IR spectroscopy (FTIR), high-resolution transmission electron microscopy (HR-TEM), field emission gun SEM (FEG-SEM), energy-dispersive X-ray spectroscopy (EDX), vibrating sample magnetometry (VSM), X-ray powder diffraction (P-XRD), XPS, photoluminescence spectroscopy and Raman spectroscopy. XPS anal. confirms the presence of Cu as Cu¹⁺ and Cu²⁺ by the effect of the linker in IL@CuFe₂O₄-L-Tyr-TiO₂/TiTCIL. It provides an eco-friendly procedure with several advantages such as operational simplicity, water as the solvent, short reaction time, easy workup and excellent yields in the synthesis of 1,4-disubstituted-1,2,3-triazoles via Click reaction. The catalyst showed recyclability up to seven runs in Click reaction and the recycled catalyst was also characterized by HR-TEM, FEG-SEM and XPS. In Click reaction, one single crystal of 1-benzyl-4-phenyl-1H-1,2,3-triazole was grown. Its energetic features, non-covalent interactions, mol. electrostatic potential surfaces, and packing arrangement were calculated by using the B3LYP-D3/def2-TZVP level of theory and the Bader’s quantum theory of “Atoms in mols.” (QTAIM). Moreover, IL@CuFe₂O₄-L-Tyr-TiO₂/TiTCIL also displayed good photocatalytic activity in the degradation of methylene blue dye in visible light.

Synthetic Route of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, HPLC of Formula: 4224-70-8

Sharma, Gyanendra;Takahashi, Kenji;Kuroda, Kosuke research published 《 Polar zwitterion/saccharide-based deep eutectic solvents for cellulose processing》, the research content is summarized as follows. Liquid zwitterions are biocompatible cellulose solvents and have enabled successive ethanol production from plant biomass in the same reaction pot. However, only a few carboxylate-type liquid zwitterions have been reported since almost all zwitterions are solid. Here, we propose zwitterion-based deep eutectic solvents (DESs) to expand the choices of zwitterionic solvents for cellulose dissolution and the subsequent processing. Zwitterion-based DESs were prepared by mixing four types of saccharide at various ratios. Twenty-two combinations of zwitterion/saccharide mixtures formed DESs, i.e., liquid state below 100°C. Two of them, whose saccharide ratio were 5 wt%, successfully dissolved cellulose because the low saccharide load was sufficient for liquefaction but did not disrupt the intrinsic cellulose dissolution ability of zwitterions.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., HPLC of Formula: 4224-70-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Formula: C5H7BrO3

Sharafian, Shirin;Hossaini, Zinatossadat;Rostami-Charati, Faramarz;Khalilzadeh, Mohammad A. research published 《 Ultrasound-promoted Green Synthesis of Pyrido[2,1-a]isoquinoline Derivatives and Studies on their Antioxidant Activity》, the research content is summarized as follows. In this work, synthesis of pyrido[2,1-a]isoquinolines I (R = EtO₂C, 4-MeOC₆H₄, 4-MeC₆H₄, 4-BrC₆H₄, 4-O₂NC₆H₄; R¹ = H, MeO₂C, EtO₂C; R² = Me, Et) via multicomponent reaction of phthalaldehyde, methylamine, α-bromo carbonyls RC(O)CH₂Br, activated acetylenic compounds R¹CCCO₂R² and triphenylphosphine in water under ultrasonic irradiation conditions at room temperature in excellent yields in short time was performed. The subsequent Diels-Alder reaction of pyrido[2,1-a]isoquinolines I (R = EtO₂C, 4-MeOC₆H₄, 4-MeC₆H₄, 4-O₂NC₆H₄; R¹ = MeO₂C, EtO₂C; R² = Me, Et) with activated acetylenic compounds R¹CCCO₂R² afforded the corresponding adducts II. Adducts II were also prepared directly from phthalaldehyde, α-bromo carbonyls and acetylenic compounds without isolation of the intermediate pyrido[2,1-a]isoquinolines. Also, the antioxidant activities of four compounds I were evaluated by DPPH radical scavenging and ferric reducing power anal. (FRAP). The compound I (R = EtO₂C; R¹ = MeO₂C; R² = Me) exhibited excellent DPPH radical scavenging activity and FRAP compared to synthetic antioxidants BHT and TBHQ. The chief benefits of the method are high atom economy, green reaction conditions, higher yield, shorter reaction times, and easy work-up, which agree with some principles of green chem.

Formula: C5H7BrO3, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Safety of Methyl 4-bromobutanoate.

Shao, Lihua;Bai, Yue;Wang, Qiutang;Chen, Zizhang;Xie, Yundong;Bian, Xiaoli research published 《 Design, synthesis and evaluation of 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione-Based fibrates as potential hypolipidemic and hepatoprotective agents》, the research content is summarized as follows. Six novel target compounds, 5-(4-hydroxyphenyl)-3H-1,2-dithiole-3-thione (ADT) based fibrates I [R¹ = R² = Me, n = 0; R¹ = Et, R² = H, n = 0; R¹ = Me, R² = H, n = 0; R¹ = R² = H, n = 2, 3, 4], were synthesized and evaluated. All the synthesized compounds were preliminarily screened by using the Triton WR-1339-induced hyperlipidemia model, in which I [R¹ = R² = Me, n = 0] (II) exhibited more potent hypolipidemic property than pos. drug fenofibrate (FF). II also significantly decreased serum triglycerides (TG), total cholesterol (TC) and low d. lipoprotein cholesterin (LDL) in methionine solution (Mets) induced hyperlipidemic mice. Moreover, hepatic transaminases (AST and ALT) were obviously ameliorated after treatment with II and the histol. observation indicated that II ameliorated the injury in liver tissue and inhibited the hepatic lipid accumulation. In the livers of II-administrated rat, the levels of PPARα related to lipids metabolism were up-regulated. Addnl. effects such as antioxidant, anti-inflammatory and H₂S releasing action confirmed and reinforced the activity of II as a potential multifunctional hypolipidemic and hepatoprotective agent.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Safety of Methyl 4-bromobutanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Quality Control of 20469-65-2.

Shao, Li-Dong;Chen, Yang;Wang, Mei;Xiao, Nan;Zhang, Zhi-Jun;Li, Dashan;Li, Rong-Tao research published 《 Palladium-catalyzed direct γ-C(sp³)-H arylation of β-alkoxy cyclohexenones: reaction scope and mechanistic insights》, the research content is summarized as follows. A mild Pd-catalyzed method for direct γ-C(sp³)-arylation of various unactivated β-alkoxy cyclohexenones was reported. The method is not only tolerated well with many ortho-hetero substituted aryl bromides but also with the sterically hindered ortho-dimethoxy or rigid ortho-diaryl aryl bromides. Mechanistic studies suggested the tunneling was likely to govern the [1,5]-H shift of the α’-dienolate-PdArL intermediate and consequently forms the γ-arylated product, therefore exhibiting an excellent γ-site selectivity. Finally, this method enabled the facile synthesis of CBD-like compounds with selective anti-proliferative effects against glioma stem cells.

20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., Quality Control of 20469-65-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Electric Literature of 629-04-9.

Shanker, G.;Srinatha, M. K.;Sandhya Kumari, D.;Ranjitha, B. S.;Alaasar, M. research published 《 Novel green synthetic approach for liquid crystalline materials using multi-component reactions》, the research content is summarized as follows. Synthesis of disk-shape liquid crystalline materials using multi-component reactions is reported. Two new series, the compounds I (R = n-C_nH_2n+1; n = 6, 7, 8, 10, 11, 12) and II, were synthesized by coupling either 2,3-dihydroxynaphthalene or 2,6-dihydroxynaphthalene with the corresponding 3,4,5-tris(alkoxy)anilines under solvent-free conditions. The mol. structures of the new materials were confirmed using ¹H NMR, ¹³C NMR and CHN elemental anal. The phase behavior was investigated using polarizing optical microscope and differential scanning calorimetry experiments All the materials exhibited room temperature discotic nematic phase during the cooling cycles as confirmed by X-ray diffraction studies. This synthetic approach provides multiple advantages such as high atom economy, short reaction time, mild reaction condition, simple workup, and do not require column chromatog. purification

Electric Literature of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 629-04-9, formula is C7H15Br, The most pervasive is the naturally produced bromomethane. Related Products of 629-04-9

Shangguan, Zhichun;Sun, Wenjin;Zhang, Zhao-Yang;Fang, Dong;Wang, Zhihang;Wu, Si;Deng, Chao;Huang, Xianhui;He, Yixin;Wang, Ruzhu;Li, Tingxian;Moth-Poulsen, Kasper;Li, Tao research published 《 A rechargeable molecular solar thermal system below 0 °C》, the research content is summarized as follows. An optimal temperature is crucial for a broad range of applications, from chem. transformations, electronics, and human comfort, to energy production and our whole planet. Photochem. mol. thermal energy storage systems coupled with phase change behavior (MOST-PCMs) offer unique opportunities to capture energy and regulate temperature Here, we demonstrate how a series of visible-light-responsive azopyrazoles couple MOST and PCMs to provide energy capture and release below 0 °C. The system is charged by blue light at -1 °C, and discharges energy in the form of heat under green light irradiation High energy d. (0.25 MJ kg^-1) is realized through co-harvesting visible-light energy and thermal energy from the environment through phase transitions. Coatings on glass with photo-controlled transparency are prepared as a demonstration of thermal regulation. The temperature difference between the coatings and the ice cold surroundings is up to 22.7 °C during the discharging process. This study illustrates mol. design principles that pave the way for MOST-PCMs that can store natural sunlight energy and ambient heat over a wide temperature range.

Related Products of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. COA of Formula: C6H11BrO2.

Shang, Jinyan;Li, Yanbo;Chen, Kangni;Li, Heping research published 《 Synthesis and Properties of a Water-soluble Fluorescent Probe Based on ICT System for Detection of Ultra-trace SO₂ Derivatives》, the research content is summarized as follows. SO₂ and its derivatives are widely present in the environment and living organisms, endangering the environment and human health. Therefore, it is of great significance for the effective detection of sulfur dioxide (SO₂) and its hydrated derivatives (HSO₃^– /SO₃^2-). In this study, based on the mechanism of intramol. charge transfer (ICT), a water-soluble colorimetric fluorescent probe (E)-2-(4-acetamidostyryl)-3-(5-carboxypentyl)-1, 1-dimethyl-1H-benzo[e]indol-3-ium (ABI) for the detection of SO2 derivatives was successfully synthesized from p-acetaminobenzaldehyde by connecting the benzo[e]indoles cationic fluorophore containing highly activated Me via C = C double bond, and the ABI structure was characterized by HRMS and 1H NMR, 13 C NMR. Studies have shown that the ABI probe has some advantages such as good selectivity for SO2 derivatives, high sensitivity (detection limit LOD = 14.9 nM), and fast reaction rate. After adding HSO3-, the color of the probe solution changed from light yellow to colorless within 10 s, which provides a simple way to identify bisulfite with the naked eye. Studies on the effect of pH on the fluorescence performance of ABI showed that fluorescence performance of ABI was stable in the range of pH (7.0-10.26). Therefore, ABI is expected to become an effective tool for detecting SO2 derivatives in cells and organisms in the future.

COA of Formula: C6H11BrO2, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary