Author: Jessica.F

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Organic compounds having carbon bonded to bromine are called organic bromides. Safety of Methyl 2-bromopropanoate.

Chin, Kek Foo;Ye, Xinyi;Li, Yongxin;Lee, Richmond;Kabylda, Adil M.;Leow, Dasheng;Zhang, Xin;Xia Ang, Esther Cai;Tan, Choon-Hong research published 《 Bisguanidinium-Catalyzed Epoxidation of Allylic and Homoallylic Amines under Phase Transfer Conditions》, the research content is summarized as follows. A highly enantioselective epoxidation reaction of allylic and homoallylic amines has been disclosed using an ion pair catalyst, which consists of chiral cationic bisguanidinium [BG]²⁺ and an achiral tetraperoxyditungstate anion [W₂O₂(μ-O)(O₂)₄]^2-. The terminal oxidant is a stoichiometric amount of aqueous hydrogen peroxide, an environmentally benign reagent. Up to 96% enantiomeric excess and 99% yields were achieved for 1,1′-disubstituted and 1,2-disubstituted allylic protected amines and 1,2-disubstituted homoallylic protected amines. The identity of the ion pair catalyst was uncovered using X-ray crystallog. and revealed that the achiral tetraperoxyditungstate anion species [W₂O₂(μ-O)(O₂)₄]^2- is nudged nicely into the central cavity of the chiral dication. The ion pair catalyst was also characterized using IR (IR) and Raman spectroscopies. The synthesis of (-)-venlafaxine was achieved via this reported methodol. to demonstrate its usefulness.

Safety of Methyl 2-bromopropanoate, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 244205-40-1, formula is C6H6BBrO2, The most pervasive is the naturally produced bromomethane. Name: (2-Bromophenyl)boronic acid

Cheng, Xiu-Fen;Yu, Ting;Liu, Yi;Wang, Nan;Chen, Zhenzhen;Zhang, Guang-Lu;Tong, Lili;Tang, Bo research published 《 Palladium(II)-Catalyzed C(sp²)-H Bond Activation/C-N Bond Cleavage Annulation of N-Methoxy Amides and Arynes》, the research content is summarized as follows. The Pd(II)-catalyzed C-H bond activation/C-N bond cleavage annulation reaction of N-alkyoxyamide aryne was developed to synthesize 9,10-dihydrophenanthrenone derivatives I [R¹ = H, 3-Me, 2-MeO, etc.; R² = Me, n-Pr, i-Pr, n-Bu, Ph, cyclohexyl; R³ = Me, n-Bu, Ph; R⁴ = H, 7-F, 6,7-di-MeO, etc.; R²R³ = (CH₂)₄, (CH₂)₅, (CH₂)₂O(CH₂)₂]. This reaction exhibited good functional group compatibility with yields up to 92%. Detailed mechanistic studies showed that the key to C-N bond cleavage was the formed eight-membered palladacycle intermediate undergoing nucleophilic addition to the carbonyl group, which provided a new and practical way for N-alkoxyamide directed C-H bond activation.

Name: (2-Bromophenyl)boronic acid, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., 244205-40-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 5392-10-9, formula is C9H9BrO3, Name is 2-Bromo-4,5-dimethoxybenzaldehyde. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Reference of 5392-10-9.

Cheng, Xionglve;Wang, Lili;Liu, Yide;Wan, Xiao;Xiang, Zixin;Li, Ruyi;Wan, Xiaobing research published 《 Molecular iodine-catalysed reductive alkylation of indoles: late-stage diversification for bioactive molecules》, the research content is summarized as follows. A mol. iodine-catalyzed reductive alkylation of indoles with carbonyl compounds using Et₃SiH for the efficient synthesis of C-3 alkylated indoles was reported. This metal-free and environmental-friendly process exhibited excellent functional group tolerance, mild conditions and wide substrate scope. Notably, the synthetic usefulness of this strategy to pharmacochem. was highlighted by the late-stage modification of drug-like mols.

5392-10-9, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., Reference of 5392-10-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Electric Literature of 4897-84-1.

Cheng, Junfei;Li, Yu;Wang, Xu;Dong, Guoqiang;Sheng, Chunquan research published 《 Discovery of Novel PDEδ Degraders for the Treatment of KRAS Mutant Colorectal Cancer》, the research content is summarized as follows. KRAS-PDEδ protein-protein interaction represents an appealing target for cancer therapy. However, fast release of high-affinity inhibitors from PDEδ hampered drug binding affinity and antiproliferative activity. To overcome the limitations, the first proteolysis-targeting chimeric (PROTAC) small mols. targeting PDEδ were designed. By employment of PDEδ inhibitor deltazinone (2) and cereblon ligand pomalidomide (6), a series of potent PROTAC PDEδ degraders were obtained. The most promising compound 17f(I) efficiently induced PDEδ degradation and demonstrated significantly improved antiproliferative potency in KRAS mutant SW480 cells. Compound 17f also achieved significant tumor growth inhibition in the SW480 colorectal cancer xenograft model. This proof-of-concept study provided a new strategy to validate the druggability of KRAS-PDEδ interaction and offered an effective lead compound for the treatment of KRAS mutant cancer.

Electric Literature of 4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., 4897-84-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Synthetic Route of 6911-87-1.

Cheng, Hanchao;Lam, Tsz-Lung;Liu, Yungen;Tang, Zhou;Che, Chi-Ming research published 《 Photoinduced Hydroarylation and Cyclization of Alkenes with Luminescent Platinum(II) Complexes》, the research content is summarized as follows. Photoinduced hydroarylation of alkenes is an appealing synthetic strategy for arene functionalization. Herein, we demonstrated that aryl radicals generated from electron-deficient aryl chlorides/bromides could be trapped by an array of terminal/internal aryl alkenes in the presence of [Pt(ON̂ĈN̂)] under visible-light (410 nm) irradiation, affording anti-Markonikov hydroarylated compounds in up to 95% yield. Besides, a protocol for [Pt(ON̂ĈN̂)]-catalyzed intramol. photocyclization of acrylanilides to give structurally diverse 3,4-dihydroquinolinones has been developed.

Synthetic Route of 6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., 6911-87-1.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Electric Literature of 20469-65-2.

Cheng, Fei;Chen, Tao;Huang, Yin-Qiu;Li, Jia-Wei;Zhou, Chen;Xiao, Xiao;Chen, Fen-Er research published 《 Copper-Catalyzed Ullmann-Type Coupling and Decarboxylation Cascade of Arylhalides with Malonates to Access α-Aryl Esters》, the research content is summarized as follows. Authors have developed a high-efficiency and practical Cu-catalyzed cross-coupling to directly construct versatile α-aryl-esters by utilizing readily available aryl bromides (or chlorides) and malonates. These gram-scale approaches occur with turnovers of up to 1560 and are smoothly conducted by the usage of a low catalyst loading, a new available ligand, and a green solvent. A variety of functional groups are tolerated, and the application occurs with α-aryl-esters to access nonsteroidal anti-inflammatory drugs (NSAIDs) on the gram scale.

Electric Literature of 20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., 20469-65-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 20469-65-2, formula is C8H9BrO2, Name is 1-Bromo-3,5-dimethoxybenzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Reference of 20469-65-2.

Cheng, Bao;Zhu, Guirong;Meng, Linghua;Wu, Guolin;Chen, Qin;Ma, Shengming research published 《 Identification and optimization of biphenyl derivatives as novel tubulin inhibitors targeting colchicine-binding site overcoming multidrug resistance》, the research content is summarized as follows. Microtubule targeting agents (MTAs) are among the most successful chemotherapeutic drugs, but their efficacy is often limited by the development of multidrug resistance (MDR). Therefore, the development of novel MTAs with the ability to overcome MDR is urgently needed. In this contribution, through modification of the unsym. biaryl compounds, we discovered a novel compound dxy-1-175 with potent anti-proliferative activity against cancer cells. Mechanistic study revealed that dxy-1-175 inhibited tubulin polymerization by interacting with the colchicine-binding site of tubulin, which caused cell cycle arrest at G2/M phase. Based on the predicted binding model of dxy-1-175 with tubulin, a series of new 4-benzoylbiphenyl analogs were designed and synthesized. Among them, the hydrochloride compound 12e with improved solubility and good stability in human liver microsome, exhibited the most potent anti-proliferative activity with IC50 value in the low nanomolar range, and markedly inhibited the growth of breast cancer 4T1 xenograft in vivo. Notably, 12e effectively overcame P-gp-mediated MDR and our preliminary data suggested that 12e may not be a substrate of P-glycoprotein (P-gp). Taken together, our study reveals a novel MTA 12e targeting the colchicine-binding site with potent anticancer activity and the ability to circumvent MDR.

20469-65-2, 1-Bromo-3,5-dimethoxybenzene, also known as 1-Bromo-3,5-dimethoxybenzene, is a useful research compound. Its molecular formula is C8H9BrO2 and its molecular weight is 217.06 g/mol. The purity is usually 95%.
1-Bromo-3,5-dimethoxybenzene is used as an intermediate in the synthetic preparation of pharmaceutical inhibitors via cross-coupling reactions.
1-Bromo-3,5-dimethoxybenzene can be synthesized by using 1,3-dimethoxybenzene via iridium-catalyzed arene borylation.
1-Bromo-3,5-dimethoxybenzene (1BDMB) is a synthetic molecule that can be used as an electron acceptor in organic photovoltaic cells. 1BDMB is a salt of the sodium salt of resorcylic acid and 1,3-dibromo-5,5-dimethoxybenzene. It has been shown to have a radical mechanism for the generation of free radicals. The radical mechanism is initiated by light absorption by the ruthenium complex at the center of the molecule which induces photoinduced electron transfer from the ruthenium to 1BDMB. This process results in electron transfer from the donor to an acceptor molecule, such as oxygen or nitrogen. The pharmacokinetic properties of this compound are not well known; however, it has been demonstrated that it can be synthesized through a cross-coupling reaction with other aromatic compounds such as stemofuran., Reference of 20469-65-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 4897-84-1, formula is C5H9BrO2, Name is Methyl 4-bromobutanoate. Organic compounds having carbon bonded to bromine are called organic bromides. Reference of 4897-84-1.

Chen, Zimin;Zheng, Songlin;Wang, Zijie;Liao, Zixuan;Yuan, Weiming research published 《 Electron Donor-Acceptor Complex Enabled Photocyanation of Tertiary Amines with a Stable and User-Friendly Cyanobenziodoxolone Reagent》, the research content is summarized as follows. A visible light-induced photocyanation of tertiary amines e.g., 1-((trimethylsilyl)methyl)piperidine by a stable, less-toxic and user-friendly CN reagent cyanobenziodoxolone (CBX) was developed. This cyanation process does not require any photocatalyst, oxidant, base or additives, and represents a set of extremely mild and succinct reaction conditions and a broad substrate scope. In addition to the frequently used N-aryl amine derivatives e.g, 2-thiomorpholinoacetonitrile, more challenging tertiary aliphatic amines (modified by a α-silyl substituent) can also be photocyanated smoothly. Mechanistic studies reveal that the cyanation reaction is enabled by an electron donor-acceptor (EDA) complex formed by the interaction between the amine and the cyanobenziodoxolone reagent.

4897-84-1, Methyl 4-bromobutyrate,also as known as 4-Bromobutyric acid methyl ester, is a useful research compound. Its molecular formula is C5H9BrO2 and its molecular weight is 181.03 g/mol. The purity is usually 95%.
4-Bromobutyric acid methyl ester is a synthetic compound that can be used to inhibit the activity of the G1 phase cyclin-dependent kinases. It has been shown to inhibit protein synthesis by alkylating the amino groups of proteins and fatty acids. 4-Bromobutyric acid methyl ester also inhibits the growth of cancer cell lines, such as renal carcinoma cells. The mechanism of action for this drug is not well understood, but it may be due to its ability to bind with monoclonal antibodies and enter kidney cells by passive diffusion., Reference of 4897-84-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4224-70-8, formula is C6H11BrO2, The most pervasive is the naturally produced bromomethane. Related Products of 4224-70-8

Chen, Zhen;Xie, Huan-Yin;Li, Yi-Jing;Chen, Gui-E.;Xu, Sun-Jie;Xu, Zhen-Liang research published 《 Smart light responsive polypropylene membrane switching reversibly between hydrophobicity and hydrophilicity for oily water separation》, the research content is summarized as follows. Smart membranes with switchable wettability are perfect choices for oily water separation, which limited in numerous practical applications as before. Hereof, one method of chem. grafting azobenzene groups on SiO2 roughened polypropylene (PP) membranes has been realized. This smart membrane surface reveals rapid light-triggered wettability transition between hydrophobicity and hydrophilicity through alternate irradiation with UV and Vis light, resp. After modification, maximal water contact angle (WCA) of 160° is obtained in the trans state of 7-[(trifluoromethoxyphenylazo)phenoxy]pentanoic acid (CF₃AZO), which convert into cis state by UV (365 nm) irradiation In cis state, since the high free energy of CF₃AZO, hydrophilic surface (WCA ≤ 5°) is acquired and can swap back to trans state under Vis (440 nm) irradiation Simultaneously, the photosensitive membranes possess exceptional phys. and chem. stabilities, which can endure cruel ambient conditions and repeated mech. deformation along with multiple rinsing. What’s more, on account of the outstanding photosensitivity, multifarious eliminable and reproducible patterns with apparent wetting characteristics upon optional illumination can be acquired. The pos. outcomes indicate that photosensitive CF₃AZO grafted PP membranes with outstanding switchable wettability is a prospective material for oil/water separation membranes.

Related Products of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Category: bromides-buliding-blocks.

Chen, Zhangxin;Mei, Shiwei;Li, Weijun;Xu, Ning;Dong, Yujie;Jin, Yanxian;Ouyang, Mi;Zhang, Cheng research published 《 Study of multi-electron redox mechanism via electrochromic behavior in hexaazatrinaphthylene-based polymer as the cathode of lithium-organic batteries》, the research content is summarized as follows. The charging and discharging mechanism of lithium-organic batteries has always been a challenging issue due to the lack of popularity of in situ characterization technol. during the charge/discharge process. In this article, a novel open lithium battery test combining the in situ electrochem. and UV spectral tests is firstly studied to explore the multi-electron redox mechanism of hexaazatrinaphthylene-based polymers as a cathode of lithium-organic batteries. Two triphenylamine-hexanazonaphthalene structure conjugated microporous polymers (PTPA-HATN and PDTPA-HATN) have been synthesized as models to study the charging and discharging mechanism of hexazanaphthalene. Both possess similar nanosphere morphol. and high surface area (~450 mA h g^-1) as well as abundant microporous structure. Using them as cathodes to explore the lithium battery performance, an obvious charge-discharge process with multi-electron redox characteristics can be observed in both, and the one with PTPA-HATN shows a higher discharge capacity (~168 mA h g^-1) and better rate performance than those of PDTPA-HATN in LiClO₄ electrolyte. Combining the in situ electrochem. and UV spectral results, a new multi-electron redox mechanism of hexanazonaphthalene-based polymer cathodes in lithium-organic batteries is proposed. Different from the previously reported mechanisms, the N and N lone electron pairs of the hexanazonaphthalene group in the polymer film will adsorb Li⁺ to form the N-Li-N bond in the electrolytes with low HF acid content accompanied with the red shift of absorption peak in the spectra under the open circuit voltage. During the discharge process, the N-Li-N bond will break and combine with the newly entered Li⁺ to form the N₂-Li₂ bond, resulting in a new large blueshift in the spectra. This work may provide new insight into the redox mechanism of functional groups of organic cathode materials via electrochromic behavior on the performance of lithium batteries.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary