Category: 111-83-1

Gong, Jun published the artcileCircularly polarized luminescent 4,4′-bicarbazole scaffold for facile construction of chiroptical probes, Safety of 1-Bromooctane, the publication is Dyes and Pigments (2022), 109969, database is CAplus.

Small mols. with circularly polarized luminescence (CPL) are especially valuable in solution-based applications, like chiroptical probes for effective sensing. Such application was not well explored due in part to hard introduction of appropriate triggerable fluorophores. An easily post-modifiable CPL-active scaffold (4) is reported, and a feasible strategy to construct chiroptical probes for sensing hypochlorous acid is further proposed. Helically chiral 4 with a 4,4′-bicarbazole scaffold exhibits a large Stokes shift ≤142 nm and g_lum value of 0.9 × 10^-3. Through facile construction of phenothiazine moiety on 4, red-emitting compound 5 was obtained in high yield (85.3%), showing distinct optical and chiroptical responses towards hypochlorous acid with good liner relations and CPL sign blue-shifting of 120 nm in vitro. The probe is also applied to detect endogenous hypochlorous acid in living macrophages and can serve as a CPL sensor. Taking 5 as an application example, the authors envision that CPL-enabling scaffold 4 could find broad use in the design of more chiroptical probes.

Dyes and Pigments published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Safety of 1-Bromooctane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Herron, Alastair N. published the artcileδ-C-H Halogenation Reactions Enabled by a Nitrogen-Centered Radical Precursor, Application of 1-Bromooctane, the publication is Organic Letters (2022), 24(20), 3652-3656, database is CAplus and MEDLINE.

Herein, new hydrazonyl carboxylic acids RN(S(O)₂R¹)N=C(Me)C(O)OH (R = octyl, 2-(adamantan-1-yl)ethyl, 4-methylpentyl, etc.; R¹ = 4-methylphenyl, 4-methoxyphenyl, 4-bromophenyl, 4-(trifluoromethyl)phenyl) precursor to nitrogen-centered radicals and its application toward remote C-H fluorination and chlorination reactions of sulfonyl-protected alkyl amines R¹S(O)₂NHR² (R² = 4-fluorooctyl, 2-(2-fluorocyclobutyl)ethyl, 4-fluoro-4-methylpentyl, etc.) via 1,5-HAT were disclosed.

Organic Letters published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Application of 1-Bromooctane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Xiong, Wenjing published the artcileSynthesis and optoelectronic properties of a dinuclear iridium (III) complex containing a picolinic acid derivative by nonconjugated linkage with a D-A-D core, HPLC of Formula: 111-83-1, the publication is Journal of Organometallic Chemistry (2022), 122202, database is CAplus.

A novel dinuclear iridium (III) complex containing a non-conjugated bridging picolinic acid ligand of (C₈TPAPhOC₂FIrpic)₂BT with a D-A-D core was synthesized and characterized, in which the D-A-D core consists of benzo[c][1,2,5]thiadiazole (BT) and triphenylamino (TPA) units. Its optophys., electrochem. and electroluminescent characteristics were primarily studied. It is found this dinuclear iridium (III) complex exhibited similar photoluminescent and electroluminescent profiles, but higher brightness and efficiency in compared with the picolinic acid ligand in the single-emissive-layer organic light-emitting devices. The maximum luminance of 7404 cd/m² and current efficiency of 0.81 cd/A was obtained in the (C₈TPAPhOC₂FIrpic)₂BT-based devices. The efficient energy transfer is observed from the terminal iridium complex unit to the picolinic acid ligand. This work demonstrates that the picolinic acid ligand with a D-A-D core can facilitate dinuclear iridium (III) complex to exhibit the ancillary ligand-based red emission.

Journal of Organometallic Chemistry published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C4H3Cl2N3, HPLC of Formula: 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

He, Guohang published the artcileFacile synthesis of poly(BODIPY)s via solid state polymerization and application in temperature sensor, Name: 1-Bromooctane, the publication is Polymer (2022), 124514, database is CAplus.

Several 3,5-dibromo substituted BODIPY (4,4′-Difluoro-4-bora-3a,4a-diaza-s-indacene) derivatives were rationally designed and investigated as potential candidates to perform solid state polymerization (SSP). Compared with the traditional systems of thiophene and diacetylene families, which were successfully applied in SSP, SSP has been expanded to the BODIPY system in this article. In addition, crystallog. data of BODIPY derivative was derived to analyze the reasonable path of SSP, which could further explore the mechanism of SSP. Furthermore, the relationship between fluorescence intensity of BODIPY after SSP and temperature was established, which could apply this material in temperature fluorescence sensor with outstanding relative sensitivity (S_r) of 0.898% K^-1. Our work has been proved to pave the way to explore more conjugated systems by using SSP method and enrich SSP database systematically.

Polymer published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Name: 1-Bromooctane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Cui, Ning published the artcileNickel-Catalyzed Reductive Coupling of γ-Metalated Ketones with Unactivated Alkyl Bromides, Application In Synthesis of 111-83-1, the publication is Organic Letters (2022), 24(22), 3987-3992, database is CAplus and MEDLINE.

A nickel-catalyzed reductive cross-coupling reaction of aryl cyclopropyl ketones with easily accessible unactivated alkyl bromides to access aryl alkyl ketones was developed. This strategy facilitated access to various of γ-alkyl substituted ketones via ring opening of cyclopropyl ketones (26 examples, 50-90% yield). Initial mechanistic studies revealed that the reaction proceeds via a radical cleavage of the alkyl bromide.

Organic Letters published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Application In Synthesis of 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Li, Songyi published the artcileTransition Metal Free Stannylation of Alkyl Halides: The Rapid Synthesis of Alkyltrimethylstannanes, Formula: C8H17Br, the publication is Journal of Organic Chemistry (2022), 87(6), 4291-4297, database is CAplus and MEDLINE.

A transition metal free stannylation reaction of alkyl bromides and iodides with hexamethyldistannane was developed. This protocol is operationally convenient and features a rapid reaction and good functional group tolerance. A wide range of functionalized primary and secondary alkyl and benzyl tri-Me stannanes were prepared in moderate to excellent yields. The success of the gram-scale procedure and tandem Stille coupling reaction has allowed this protocol to demonstrate potential for application in organic synthesis. Both exptl. and theor. studies reveal the mechanistic details of this stannylation reaction.

Journal of Organic Chemistry published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Formula: C8H17Br.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Pan, Xiujiao published the artcileBiosafety-inspired structural optimization of triazolium ionic liquids based on structure-toxicity relationships, Related Products of bromides-buliding-blocks, the publication is Journal of Hazardous Materials (2022), 424(Part_C), 127521, database is CAplus and MEDLINE.

Ionic liquids (ILs), owing to their low vapor pressure and excellent solvating ability, are being increasingly applied in various industries to replace highly toxic organic solvents. They mainly pollute aquatic environment and soils, directly endangering eco-environment and human health. Therefore, it is critical to understand and optimize structural motifs of ILs with reduced toxicity. Considering human oral exposure is the major route, our investigations employed a human cell panel (modeling oral exposures) including human stomach (GES-1), intestinal (FHC), liver (HepG2) and kidney (HEK293) cells using a series of exptl. and computational approaches to explore the cytotoxicity and mol. mechanism of ILs. We discovered that the cytotoxicity of triazolium and imidazolium ILs was human cell line-dependent with cytotoxicity in an order of FHC > GES-1 > HepG2 > HEK293. For this reason, a toxicity assay using a single cell line was highly inappropriate. Compared to anions (Br-, OTs-, OTMBS-) we tested, the cation of ILs played a major role in causing cytotoxicity. Ionic liquids with cations having longer hydrophobic sidechains (IL09 vs. IL01) readily insert into cell membranes with enhanced membrane and lipidomic perturbations, induce cytotoxicity by triggering cell cycle arrest and apoptosis. Reducing sidechain length and incorporating three nitrogen atoms (triazolium) instead of two (imidazolium) in the cation core alleviated cytotoxicity by reducing cell membrane perturbations and cell function interference. These findings provide important guiding principles for the design of the next-generation of “green” and safe ILs.

Journal of Hazardous Materials published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kong, Qunshou published the artcileN-Arylimidazoliums as Highly Selective Biomimetic Antimicrobial Agents, HPLC of Formula: 111-83-1, the publication is Journal of Medicinal Chemistry (2022), 65(16), 11309-11321, database is CAplus and MEDLINE.

Antibiotic resistance has become one of the greatest health threats in the world. In this study, a charge-dispersed dimerization strategy is described for the antimicrobial peptide (AMP) mimics via a tunable cationic charge to improve the selectivity between prokaryotic microbes and eukaryotic cells. This strategy is demonstrated with a series of charge-dispersed AMP mimics based on N-arylimidazolium skeletons. These N-arylimidazolium AMP mimics show potent antibacterial activity against strains along with a low rate of drug resistance, good hemocompatibility, and low cytotoxicity. In addition to the elimination of planktonic bacteria, N-arylimidazolium AMP mimics can also inhibit biofilm formation and destroy the established biofilm. More importantly, methicillin-resistant Staphylococcus aureus (MRSA)-induced lung-infected mice can be effectively treated by the i.v. administration of N-arylimidazolium AMP mimic, which enable the design of N-arylimidazolium AMP mimics to offer an alternative avenue to eradicate drug-resistant bacterial infection.

Journal of Medicinal Chemistry published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, HPLC of Formula: 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Zhong, Mingmin published the artcileSynthesis of CoNi-layered double hydroxide on graphene oxide as adsorbent and construction of detection method for taste and odor compounds in smelling water, Safety of 1-Bromooctane, the publication is Journal of Hazardous Materials (2022), 128227, database is CAplus and MEDLINE.

Taste and odor (T&O) compounds are important water pollutant, some of which are toxic. The relevant studies are all expand upon the well-known T&O compounds but for the unknown odors in smelling water. In this work, a method combining purge and trap with gas chromatograph-mass spectrometer (PT-GC/MS) and disperse solid-phase extraction with gas chromatograph (GC) was first proposed to detect T&O compounds in unknown odorous water accurately. Firstly, PT-GC/MS was used for a qual. test on unknown odors in smelling water and determine the analytes. The hollow CoNi-layered double hydroxide (LDH) on graphene oxide (GO) was then used as a composite adsorbent to pretreat the water, in which the GO provided large sp. surface, and the LDH worked as a confinement cavity to enhance capture and retention capacity for volatile organic compounds (VOCs). According to the properties of T&O compounds determined by PT-GC/MS in water, a corresponding GC method was established for accurately quant. anal. In this paper, five T&O compounds were detected simultaneously, including di-Me sulfide, meistylene, N, N-dimethylbenzylamine, 2, 4-dimethylbenzaldehyde and 2, 4-di-tert-butylphenol. Extraction parameters were optimized, including ratio of desorption solvent, amount of adsorbent, pH value, etc. Under the optimal conditions, the detection limits for anal. were 1.14 μg/L to 3.07 mg/L. The satisfactory recoveries were 94-98%. Furthermore, two optimal determination outcomes of odor waters from different places support the practicability of the method, which is expected to be widely used in the detection of unknown odors in smelling water.

Journal of Hazardous Materials published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C18H28N2O7, Safety of 1-Bromooctane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Malysheva, S. F. published the artcileChemoselective Synthesis of Alkylphosphinic Acids from Red Phosphorus and Alkyl Bromides in the System KOH/H₂O/Toluene/Micellar Catalyst, Computed Properties of 111-83-1, the publication is Russian Journal of Organic Chemistry (2022), 58(2), 192-199, database is CAplus.

Alkylphosphinic acids, including long-chain ones, were synthesized in up to 76% yields from red P and n-AlkBr (Alk = C₄-C₁₄) under micellar catalysis conditions. The reaction proceeds efficiently and chemoselectively upon heating (85-90°, 6 h) in a KOH/H₂O/toluene/cetyltrimethylammonium bromide system.

Russian Journal of Organic Chemistry published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, Computed Properties of 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary