Category: 3893-18-3

Rueping, Magnus; Sugiono, Erli; Merino, Estibaliz published the artcile< Asymmetric iminium ion catalysis: an efficient enantioselective synthesis of pyranonaphthoquinones and β-lapachones>, Safety of 3-(4-Bromophenyl)acrylaldehyde, the main research area is asym synthesis pyranonaphthoquinone addition cyclization aliphatic aromatic aldehyde hydroxynaphthoquinone; lapachone derivative asym synthesis pyranonaphthoquinone.

An addition-cyclization reaction cascade triggered by an organocatalyst was used for the enantioselective preparation of a series of biol. active 1,2- and 1,4-pyranonaphthoquinones, e.g. I, from aliphatic and aromatic α,β-unsaturated aldehydes and 2-hydroxy-1-4-naphthoquinone. A trimethylsilyl-protected diarylprolinol serves as the Lewis base organocatalyst.

Angewandte Chemie, International Edition published new progress about Addition reaction catalysts. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Safety of 3-(4-Bromophenyl)acrylaldehyde.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gan, Zengyu; Huang, Jianping; Chen, Jinyin; Nisar, Muhammad Farrukh; Qi, Wenwen published the artcile< Synthesis and antifungal activities of cinnamaldehyde derivatives against Penicillium digitatum causing citrus green mold>, Application In Synthesis of 3893-18-3, the main research area is Cinnamaldehyde Penicillium antifungal activity citrus.

Penicillium digitatum (green mold) is pathogenic fungi and causes citrus fruit postharvest rotting that leads to huge economic losses across the world. The current study was aimed to develop a new derivative of cinnamaldehyde (4-methoxycinnamaldehyde) through the cross-hydroxyaldehyde condensation method with benzaldehyde substituted by a benzene ring under the catalysis of alk. reagent and, moreover, to test their antifungal potential against P. digitatum, the major citrus fruit rotting fungi. Multiple derivatives of cinnamaldehyde viz. 4-nitro CA, 4-chloro CA, 4-bromo CA, 4-Me CA, 4-methoxy CA, and 2,4-dimethoxy CA were synthesized in the current study whereas the 4-methoxy CA showed highest antifungal actions for citrus fruit postharvest rotting fungi P. digitatum. Moreover, 4-methoxy CA was found to reduce the spore germination and growth by damaging the fungal cell membrane, as well as declined the levels of reducing sugars.

Journal of Food Quality published new progress about Bases Role: BSU (Biological Study, Unclassified), BIOL (Biological Study) (reagent). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application In Synthesis of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Liu, Wen-Xing; Chen, Si-Kai; Tian, Jin-Miao; Tu, Yong-Qiang; Wang, Shao-Hua; Zhang, Fu-Min published the artcile< A Triazole Organocatalyst with Spiropyrrolidine Framework and its Application to the Catalytic Asymmetric Addition of Nitromethane to α,β-Unsaturated Aldehydes>, COA of Formula: C9H7BrO, the main research area is triazole spiropyrrolidine organocatalyst preparation; stereoselective nitromethane Michael addition unsaturated aldehyde.

A series of new water-compatible “”spiropyrrolidine triazole”” catalysts was designed and synthesized. The asym. Michael addition of nitromethane and α,β-unsaturated aldehydes in an aqueous system was investigated to evaluate these new catalysts, and the resulting adducts were obtained with excellent enantioselectivity (up to 95.5% ee) and moderate to good yield (63-88%).

Advanced Synthesis & Catalysis published new progress about Enantioselective synthesis. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, COA of Formula: C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Nair, Vijay; Vidya, N.; Abhilash, K. G. published the artcile< Gold(III) chloride promoted addition of electron-rich heteroaromatic compounds to the C:C and C:O bonds of enals>, Application In Synthesis of 3893-18-3, the main research area is enal electronrich heteroarene addition gold catalyst; hetaryl alkane preparation.

Electron-rich heteroaromatic compounds react with α,β-enals in the presence of gold(III) chloride to afford bis-addition products in high yields.

Tetrahedron Letters published new progress about Addition reaction. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application In Synthesis of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kim, Eunae; Park, Sehoon; Chang, Sukbok published the artcile< Silylative Reductive Amination of α,β-Unsaturated Aldehydes: A Convenient Synthetic Route to β-Silylated Secondary Amines>, Category: bromides-buliding-blocks, the main research area is silylated secondary amine preparation diastereoselective regioselective; silylative reductive amination unsaturated aldehyde diastereoselective regioselective; Lewis acidic borane; hydrosilylation; reductive amination; selectivity; α,β-unsaturated compounds.

Described here is a reductive amination/hydrosilylation cascade of α,β-unsaturated aldehydes mediated by a Lewis acidic borane catalyst. The present reaction system provides an one-pot synthetic route towards β-silylated secondary amines that have not been accessible by other previous catalysis. Comparative 1H NMR studies on the silylative reduction of enimines revealed that steric bulkiness of primary amine reactants strongly affects both catalytic efficiency and regioselectivity. This strategy was applicable to a broad range of substrates and amenable to one-pot gram-scale synthesis. Moreover, a diastereoselective introduction of the β-silyl group was also found to be feasible (d.r. up to 71:29).

Chemistry – A European Journal published new progress about Diastereoselective synthesis. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Pastushak, N. O.; Dombrovskii, A. V. published the artcile< Preparation of some unsaturated alkaryl aldehydes by reduction of nitriles of β-arylacrylic acids>, Synthetic Route of 3893-18-3, the main research area is .

Heating 8 g. appropriate nitrile of an arylacrylic acid with 50 ml. pyridine, 24 ml. AcOH, 20 g. NaH2PO2 and 3 g. Raney Ni in 25 ml. H2O at 50° 1.5 hrs. gave 55-67%: PhCH:CHCHO, b5 105°, n20D 1.6195, d20 1.050 (semicarbazone m. 208°); p-MeC6H4CH:CHCHO, m. 41°, b15 120° (semicarbazone m. 210°); p-MeOC6H4CH:CHCHO, m. 58°, b6 148° (semicarbazone m. 211°); p-ClC6H4CH:CHCHO, m. 62°, b2 115° (semicarbazone m. 231°); p-BrC6H4CH:CHCHO, m. 81°, b3 128° (semicarbazone m. 239°); PhCH:CMeCHO, b5 130°, 1.6010, 1.042 (semicarbazone m. 207°); and p-MeC6H4CH:CMeCHO, b5 118°, 1.6065, 1.040 (semicarbazone m. 220°).

Zhurnal Organicheskoi Khimii published new progress about Aldehydes. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Synthetic Route of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Thanikachalam, Venugopal; Jeeva, Palanivel; Jayabharathi, Jayaraman published the artcile< Highly efficient non-doped blue organic light emitting diodes based on a D-π-A chromophore with different donor moieties>, Synthetic Route of 3893-18-3, the main research area is organic light emitting diode chromophore.

Comparative photophys., electroluminance and theor. investigations have been made for 4′-(1-(4-morpholinophenyl)-1H-phenanthro[9,10-d]imidazole-2-yl)-styryl-2-(4′-9H-carbazole-9-yl) (MPPIS-Cz) and 4′-(1-(4-morpholinophenyl)-1H-phenanthro[9,10-d]imidazole-2-yl)-styryl-N,N-diphenyl-[1,1′-biphenyl]-4-amine (MPPIS-TPA). Based on tuning the donor ability, MPPIS-TPA and MPPIS-Cz were designed to have a hybridized local and charge transfer state (HLCT) and a hot exciton channel. This HLCT is responsible for high photoluminescence efficiency and the hot exciton contributes to high exciton utilization. The non-doped OLED based on MPPIS-Cz exhibits excellent performance: blue emission with CIE coordinates of (0.16, 0.08), maximum current efficiency of 1.52 cd A-1 and maximum external quantum efficiency of 1.42%. A fluorescent mol. with a HLCT state and hot exciton may be an ideal strategy to design next generation, high efficiency and low cost fluorescent OLED materials.

RSC Advances published new progress about Absorption spectra. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Synthetic Route of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hu, Shihe; Wang, Bingyang; Zhang, Yu; Tang, Weifang; Fang, Mengyuan; Lu, Tao; Du, Ding published the artcile< N-Heterocyclic carbene-catalyzed annulation of cyclic β-enamino esters with enals: access to functionalized indolo[2,3-a]quinolizidines>, SDS of cas: 3893-18-3, the main research area is indoloquinolizidine preparation annulation cyclic beta enaminoester enal; nitrogen heterocyclic carbene catalyzed annulation cyclic ester enal.

A novel synthetic approach to functionalized indolo[2,3-a]quinolizidines is developed via an N-heterocyclic carbene (NHC)-catalyzed annulation of cyclic β-enamino esters with enals. This methodol. offers a pathway for quick and efficient construction of an indolo[2,3-a]quinolizidine skeleton which is a core structure of many natural products with diverse bioactivities.

Organic & Biomolecular Chemistry published new progress about Cyclization. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, SDS of cas: 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Davis, Matthew C.; Groshens, Thomas J. published the artcile< Synthesis of p-Quinquephenyl from E,E-1,4-Bis(4-bromophenyl)-1,3-butadiene>, Product Details of C9H7BrO, the main research area is quinquephenyl bisbromophenyl butadiene.

P-Quinquephenyl was synthesized in five steps from E,E-1,4-bis(4-bromophenyl)-1,3-butadiene in 34% overall yield. The butadiene was prepared in six steps from 4-bromobenzaldehyde in 35% overall yield.

Synthetic Communications published new progress about Crystal structure. 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Product Details of C9H7BrO.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhang, Jian; Gao, Yan-Shan; Gu, Bu-Ming; Yang, Wu-Lin; Tian, Bo-Xue; Deng, Wei-Ping published the artcile< Cooperative N-heterocyclic Carbene and Iridium Catalysis Enables Stereoselective and Regiodivergent [3 + 2] and [3 + 3] Annulation Reactions>, Application In Synthesis of 3893-18-3, the main research area is pyrroloindole preparation enantioselective diastereoselective regioselective; indolyl allyl carbonate enal cyclization carbene iridium catalyst; formylcyclopropane enal cyclization carbene iridium catalyst; pyridineindole preparation enantioselective diastereoselective regioselective; enal indolyl allyl carbonate cyclization carbene iridium catalyst.

A cooperative N-heterocyclic carbene (NHC)/iridium catalysis has been developed to achieve highly stereoselective and regiodivergent [3 + 2] and [3 + 3] annulation reactions of 2-indolyl allyl carbonates I (R = H, Me; R1 = H, OMe, Me, F, Cl; R1 = H, OMe, Cl) with enals R3CH=CHCHO (R1 = Ph, hexyl, 4-chlorophenyl, furan-2-yl, etc.). The use of the NHC catalyst has introduced switchable homoenolate and enolate intermediates from the common enal precursor via a simple adjustment of reaction conditions in a predictable manner. This protocol furnishes two types of biol. important products, pyrrolo[1,2-a]indoles II and pyridine[1,2-a]indoles III, with high diastereo- and enantioselectivities (up to >20:1 dr and >99% ee). Notably, all four stereoisomers of these products with two vicinal stereocenters could be afforded through permutations of the enantiomers of the two chiral catalysts. Mechanistic investigations and further computational d. functional theory calculations give an explanation of the origin of the regioselectivity. In addition, the NHC-enolate intermediate generated from formylcyclopropanes IV (R4 = Ph, tert-Bu, naphthalen-2-yl, etc.) was also compatible in this cooperative catalytic system and thus the arsenal of optically pure pyrrolo[1,2-a]indole products V was enriched.

ACS Catalysis published new progress about [3+2] Cycloaddition reaction catalysts (stereo-, regioselective). 3893-18-3 belongs to class bromides-buliding-blocks, and the molecular formula is C9H7BrO, Application In Synthesis of 3893-18-3.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary