Category: 3959-07-7

Kang, Seokwoo; Huh, Jin-Suk; Kim, Jang-Joo; Park, Jongwook published the artcile< Highly efficient deep-blue fluorescence OLEDs with excellent charge balance based on phenanthro[9,10-d]oxazole-anthracene derivatives>, Name: 4-Bromobenzylamine, the main research area is phenanthrooxazole anthracene derivative fluorescence organic light emitting diode.

Two blue fluorescent materials, m-PO-ABN and p-PO-ABN, are newly synthesized by controlling the conjugation length based on different linkages of the meta or para position between the phenanthro[9,10-d]oxazole (PO) moiety and anthracene substituted with a cyano group. The two materials emit deep-blue light with a high photoluminescence quantum yield (PLQY) in solution state. Non-doped devices fabricated using m-PO-ABN and p-PO-ABN show the EL peaks at 448 and 460 nm corresponding to the Commission Internationale de L’Eclairage (CIE) coordinates of (0.148, 0.099) and (0.150, 0.164), resp. The external quantum efficiency (EQE) values of the devices are 5.9% and 5.3% for m-PO-ABN and p-PO-ABN, resp. Transient EL measurements and optical calculation results reveal that both materials exhibit good charge balance and triplet-triplet annihilation in the devices, which may originate from enhanced bipolar characteristics due to the insertion of PO and cyano moieties.

Journal of Materials Chemistry C: Materials for Optical and Electronic Devices published new progress about Blue electroluminescence. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Name: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Deng, Lanqing; Chen, Lang; Zhu, Liangdi; Li, Yang; Ou-Yang, Jie; Wu, Shaofeng; Chen, Peng; Shen, Sheng; Guo, Junkang; Zhou, Yongbo; Au, Chak-Tong; Yin, Shuang-Feng published the artcile< Green, versatile, and scale-up synthesis of amides by aerobic oxidative amination over Ag2O/P-C3N4 photocatalyst>, Reference of 3959-07-7, the main research area is green versatile scale amide aerobic oxidative amination photocatalyst.

Being extensively applied in various fields of chem. and chem. industry, the development of a green and versatile method for the synthesis of amides is in line with the demand of sustainable chem. Herein, a direct, highly selective, and scale-up (5-20 mmol) method for photocatalytic synthesis of amides through aerobic oxidative amination of alcs. with amines was developed under visible light, room temperature, using air as the oxidant. Benefiting from the adsorption of sodium hemiaminal on catalyst lengthens the C-H bond (1.148 Å), this novel process is feasible for a broad range of functionlized amides (69 examples), especially those for drug manufacture (e.g., moclobemide and pipobroman). Imines was almost prevented with excellent amide selectivity up to 99% could be ascribed to the low energy barrier for hemiaminal dehydrogenation while that for dehydration is high (2.13 eV). This green and efficient protocol represents an ideal alternative to the currently known methods.

Chemical Engineering Science published new progress about Adsorption. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Reference of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yu, Bangkui; Zou, Suchen; Huang, Hanmin published the artcile< Palladium-Catalyzed Ring-Closing Reaction for the Synthesis of Saturated N-Heterocycles with Aminodienes and N,O-Acetals>, Application of C7H8BrN, the main research area is saturated heterocycle preparation; aminodiene acetal palladium catalyst ring closing reaction.

An efficient palladium-catalyzed ring-closing reaction of aminodienes e.g., (E)-N-(2-(benzylamino)ethyl)-4-methyl-N-(penta-2,4-dien-1-yl)benzenesulfonamide with N,O-acetals RN(R1)CH2OCH3 [R = n-Bu, Bn, (4-bromophenyl)methyl, etc.; R1 = n-Bu, Bn, (4-bromophenyl)methyl, etc.; RR1 = -(CH2)2O(CH2)2-] for the synthesis of saturated N-heterocycles e.g., (E)-N,N-dibenzyl-3-(1-benzyl-4-tosyl-1,4-diazepan-6-yl)prop-2-en-1-amine is described. The reaction is consistently operated at room temperature and tolerates a wide range of functional groups with volatile MeOH as the sole byproduct. This method provides rapid and practical access to a broad range of saturated N-heterocycles e.g., (E)-N,N-dibenzyl-3-(1-benzyl-4-tosyl-1,4-diazepan-6-yl)prop-2-en-1-amine with diverse structural backbones that are useful building blocks in natural product synthesis and drug discovery.

Journal of Organic Chemistry published new progress about Acetals Role: RCT (Reactant), RACT (Reactant or Reagent) (N, O). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Application of C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gao, Run-Duo; Shuler, Scott A.; Watson, Donald A. published the artcile< Tandem aza-Heck Suzuki and carbonylation reactions of O-phenyl hydroxamic ethers: complex lactams via carboamination>, Recommanded Product: 4-Bromobenzylamine, the main research area is hydroxamic ether arylboronic acid palladium catalyst tandem aza Heck; amine carbon monoxide hydroxamic ether tandem aza heck carbonylation; lactam preparation.

The palladium-catalyzed tandem aza-Heck-Suzuki and aza-Heck-carbonylation reactions of O-Ph hydroxamic ethers were reported. These formal alkene carboamination reactions provided highly versatile access to wide range complex, stereogenic secondary lactams and exhibited outstanding functional group tolerance and high diastereoselectivity.

Chemical Science published new progress about Alkenes Role: RCT (Reactant), SPN (Synthetic Preparation), RACT (Reactant or Reagent), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Recommanded Product: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhou, Jun; Li, Xia; Ma, Xiaoming; Sheng, Wenlong; Lang, Xianjun published the artcile< Cooperative photocatalysis of dye-TiO2 nanotubes with TEMPO+BF-4 for selective aerobic oxidation of amines driven by green light>, Quality Control of 3959-07-7, the main research area is photocatalysis dye titania nanotube selective aerobic oxidation amine.

Visible light photocatalysis could offer an eco-friendly alternative for selective transformation of organic mols. Herein, a cooperative system is created with alizarin red S (ARS), TiO2 nanotubes (TNTs), and an extra redox mediator. The electron transfer between oxidatively quenched ARS-TNTs and the redox mediator is the key to secure cooperative photocatalysis. The selective aerobic oxidation of primary and secondary amines was constructed by cooperative photocatalysis of ARS-TNTs with 2,2,6,6-tetramethylpiperidine-1-oxoammonium tetrafluoroborate (TEMPO+BF-4) driven by green light. Specifically, the activity of anatase TNTs could reach about 2.2 times that of the P25 (Aeroxide P25) TiO2 precursor. Due to increased polarity, TEMPO+BF-4 serves more efficiently for electron transfer than (2,2,6,6-tetramethylpiperidin-1-yl)oxy (TEMPO), conferring above 1.5 times of activity that of TEMPO for the selective aerobic conversion of amines. This work features the potential of designing redox mediators in amplifying cooperative photocatalysis driven by visible light.

Applied Catalysis, B: Environmental published new progress about Aromatic amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Xia; Zhang, Fulin; Wang, Yuexin; Xiong, Kanghui; Lang, Xianjun published the artcile< Extending the 2D conjugated microporous polymers linked by thiazolo[5,4-d]thiazole for green light-driven selective aerobic oxidation of amines>, Quality Control of 3959-07-7, the main research area is benzylimine preparation regioselective photochem; benzylamine aerobic oxidation thiazolothiazole microporous polymer catalyst; regioselective aerobic oxidation photocatalyst thiazolothiazole microporous polymer.

Donor-π-acceptor (D-π-A) type CMPs linked by the electron-deficient thiazolo[5,4-d]thiazole (TzTz, i.e. the acceptor) were designed by extending the donor from benzene to pyrene to broaden the visible light activity. Subsequently, two-dimensional (2D) CMPs, TzTz-CMP-Be and TzTz-CMP-Py, were constructed via a solvothermal process. The more extended π-conjugation and planar pyrene bestow upon TzTz-CMP-Py with broader absorption of visible light and higher efficiency of charge transfer than TzTz-CMP-Be. Significantly, TzTz-CMP-Py outperformed TzTz-CMP-Be in the green light-driven selective aerobic oxidation of amines RCH2NHR1 [R = Ph, pyridin-2-yl, thiophen-2-yl, etc.; R1 = H, t-Bu, Bn, 4-fluorobenzyl, etc.]. Remarkable photocatalytic performance was observed in converting a wealth of primary and secondary amines to corresponding imines RCH=NR1 with mol. oxygen (O2) over TzTz-CMP-Py. This work suggests that CMPs can be rationally designed for extensive visible light-driven selective organic transformations.

Journal of Materials Chemistry A: Materials for Energy and Sustainability published new progress about Aromatic imines Role: SPN (Synthetic Preparation), PREP (Preparation). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wu, Shaofeng; Geng, Furong; Dong, Jianyu; Liu, Long; Zhou, Yongbo published the artcile< Metal-Free Oxidative Annulation of Phenols and Amines: A General Synthesis of Benzoxazoles>, Product Details of C7H8BrN, the main research area is benzoxazole preparation; phenol amine oxidative annulation.

Under metal-free conditions, a highly general synthesis of benzoxazoles I [R = 5-i-Pr, 5,7-di-ter-Bu, 6-Ph, etc.; R1 = n-Pr, t-Bu, Ph, etc.] direct from abundant and easily available phenols and amines was developed via a modular phenol functionalization controlled by TEMPO. In the reaction, various phenols and primary amines with a broad range of functional groups were compatible, producing structurally and functionally diverse benzoxazoles I without or with trace observation of the byproducts of phenol transformation with amines. The practical synthesis, especially for drug tafamidis, demonstrated decisive advantages in generality, selectivity, efficiency, and atom- and step-economies over traditional methods, even in the cases of low yields. Mechanistically, the radical adducts of TEMPO with ortho-cyclohexa-2,4-dien-1-one radicals rather than the well-recognized cyclohexa-3,5-diene-1,2-diones might serve as intermediates.

Journal of Organic Chemistry published new progress about Aryl halides Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Product Details of C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Rong-Jian; Ling, Chun; Lv, Wen-Rui; Deng, Wei; Yao, Zi-Jian published the artcile< Cyclometalated Half-Sandwich Iridium(III) Complexes: Synthesis, Structure, and Diverse Catalytic Activity in Imine Synthesis Using Air as the Oxidant>, HPLC of Formula: 3959-07-7, the main research area is crystal structure mol iridium cyclometalated half sandwich complexes preparation; iridium cyclometalated complexes catalyst imine preparation air oxidant.

Four air-stable cyclometalated half-sandwich iridium complexes 1-4 with C,N-donor Schiff base ligands were prepared through C-H activation in moderate-to-good yields. These complexes have been well characterized, and their exact structure was elaborated on by single-crystal X-ray anal. The iridium(III) complexes 1-4 showed good catalytic activity in the imine synthesis under open-flask conditions (air as the oxidant) from primary amine oxidative homocoupling, secondary amine dehydrogenation, and the cross-coupling reaction of amine and alc. Substituents bonded on the ligands of the iridium complexes displayed little effect on the catalytic efficiency. The stability and good catalytic efficiency of the iridium catalysts, mild reaction conditions, and substrate universality showed their potential application in industrial production

Inorganic Chemistry published new progress about Alcohols Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, HPLC of Formula: 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Sun, Yue; Yang, Zi-Hui; Gu, Wen published the artcile< Synthesis, crystal structure and antifungal activity of new furan-1,3,4-oxadiazole carboxamide derivatives>, Formula: C7H8BrN, the main research area is furan oxadiazole carboxamide preparation antifungal activity crystal structure.

A series of novel furan-1,3,4-oxadiazole carboxamide derivatives I (R = H, Me, Br, Cl, F) were designed, synthesized and characterized by spectroscopic methods including HR-MS, 1H- and 13C-NMR. The crystal structure of compound I (R = Br) was determined by single-crystal X-ray diffraction. The compound crystallizes in the triclinic system, space group P1 with a = 4.7261(5), b = 10.4672(11), c = 14.5886(13) Å, α = 106.081(4)°, β = 91.043(3)°, γ = 99.456(4)°, Z = 2, V = 682.48(12) Å3, Mr = 348.16, Dc = 1.694 Mg/m3, S = 1.008, μ = 3.025 mm-1, F(000) = 348, the final R = 0.0775 and wR = 0.2080 for 2774 observed reflections (I > 2σ(I)). There are two kinds of hydrogen bonds (N(3)-H(3A)…N(2) and C(8)-H(8A)…O(3)) present in its crystal structure. The preliminary antifungal assay showed that compounds I (R = Cl, F) exhibited significant antifungal activities against several plant pathogenic fungi.

Chinese Journal of Structural Chemistry published new progress about Amides Role: PAC (Pharmacological Activity), PRP (Properties), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), PREP (Preparation), USES (Uses). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Formula: C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bouamrane, Soukaina; Khaldan, Ayoub; Maghat, Hamid; Ajana, Mohammed Aziz; Bouachrine, Mohammed; Lakhlifi, Tahar published the artcile< In-silico design of new triazole analogs using QSAR and molecular docking models>, Name: 4-Bromobenzylamine, the main research area is triazole preparation docking antifungal QSAR.

The 3D-QSAR using CoMFA and CoMSIA were carried out on series of novel triazole analogs I [R = NEt, N(CH2)3, NCH2C6H4, etc.] as antifungal agents specially to treat candida albicans. The CoMFA and CoMSIA models using twelve mols. in the training set gives a Q2 of 0.53 and 0.34 resp., and high values of R2(0.99 and 0.96 resp.). CoMFA and CoMSIA models produced the contour maps to figure out the structural requirements that influence the activity and consequently propose new mols. with high predicted activities. Mol. docking was performed to affirm the stability of the predicted compounds in the receptor with PDB code: 4uym.

Rhazes: Green and Applied Chemistry published new progress about Fungicides. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Name: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary