Category: 4224-70-8

Organic compounds having carbon bonded to bromine are called organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C6H11BrO2.

Semenova, Olga;Kobzev, Dmytro;Yazbak, Fares;Nakonechny, Faina;Kolosova, Olga;Tatarets, Anatoliy;Gellerman, Gary;Patsenker, Leonid research published 《 Unexpected effect of iodine atoms in heptamethine cyanine dyes on the photodynamic eradication of Gram-positive and Gram-negative pathogens》, the research content is summarized as follows. The introduction of heavy atoms such as iodine into organic dye mols. is known to improve the efficacy of photodynamic therapy (PDT) in general and antimicrobial photodynamic therapy (APDT) in particular. Such a phenomenon is attributed to the increasing probability of spin-orbit coupling resulting in the elevated rates of reactive species generation. In this work, we synthesize a series of novel, near-IR, iodinated heptamethine cyanine dyes containing carboxylic function and report on the unexpected effect of the increasing number of iodine atoms (up to six) on the photodynamic eradication of Gram-pos. (Staphylococcus aureus) and Gram-neg. (Escherichia coli and Pseudomonas aeruginosa) microbial pathogens. The efficacy of S. aureus photo-eradication by non-charged, zwitterionic cyanines increases with increasing the number of iodine atoms up to two, remains almost unchanged for the two-, three- and four-iodinated dyes, and reduces in the case of the hexa-iodinated cyanine. However, the mono-iodinated dye exhibits the most pronounced phototoxic effect to E. coli and P. aeruginosa. An addnl. pos. charge provided by a triethylammonium group decreases photokilling of S. aureus but improves inactivation of E. coli and P. aeruginosa.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., COA of Formula: C6H11BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application In Synthesis of 4224-70-8.

Reynoso, Eugenia;Durantini, Andres M.;Solis, Claudia A.;Macor, Lorena P.;Otero, Luis A.;Gervaldo, Miguel A.;Durantini, Edgardo N.;Heredia, Daniel A. research published 《 Photoactive antimicrobial coating based on a PEDOT-fullerene C₆₀ polymeric dyad》, the research content is summarized as follows. A photostable and photodynamic antimicrobial surface was successfully obtained and applied to photoinactivate microorganisms. This approach was based on the synthesis of a fullerene C₆₀ derivative (EDOT-C₆₀) where fullerene C₆₀ is covalently linked to 3,4-ethylenedioxythiophene (EDOT) through a 1,3-dipolar cycloaddition reaction. This dual-functional monomer bears an EDOT center connected via an alkyl chain to a fullerene C₆₀ moiety. In this structure, EDOT acts as an electropolymerizable unit that allows the film formation over conducting substrates, while fullerene C₆₀ performs the photodynamic antimicrobial activity. Electrochem. polymerization of EDOT was used to obtain stable and photodynamic polymeric films (PEDOT-C₆₀) in a controllable procedure. Cyclic voltammetry and UV-visible spectroscopy studies showed that the fullerene C₆₀ units were not altered during the electropolymerization process, obtaining surfaces with high fullerene content. Photobleaching measurements demonstrated that the electropolymerized films were highly photostable. Moreover, photodynamic properties of PEDOT-C₆₀ were compared with fullerene C₆₀ and showed that electrodeposited films were able to generate reactive oxygen species (ROS) through the two photomechanisms, producing singlet mol. oxygen (type II) and superoxide radical anion (type I). All studies demonstrated that fullerene C₆₀ moieties covalently attached to the polymeric matrix mainly conserve the photodynamic characteristics. Hence, photodynamic action sensitized by PEDOT-C₆₀ was assessed in vitro against Staphylococcus aureus. The photosensitized inactivation by the electropolymerized films on bacteria suspensions produced >99.9% reduction in S. aureus survival. Fluorescence microscopy experiments with S. aureus adhered to the PEDOT-C₆₀ surface showed a complete microbe annihilation. Also, the eradication of biofilms formed on PEDOT-C₆₀ surfaces resulted in a photokilling >99.9% after visible light irradiation Our results demonstrated that these antimicrobial photodynamic polymeric films are a promising and versatile platform to photoinactivate microorganisms and to obtain photostable self-sterilizing surfaces.

Application In Synthesis of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Electric Literature of 4224-70-8.

Roemer, Max;Goncales, Vinicius R.;Keaveney, Sinead T.;Pernik, Indrek;Lian, Jiaxin;Downes, James;Gooding, J. Justin;Messerle, Barbara A. research published 《 Carbon supported hybrid catalysts for controlled product selectivity in the hydrosilylation of alkynes》, the research content is summarized as follows. A series of Rh- and Ir-hybrid catalysts with varying tether lengths has been prepared by immobilization of Rh^I, Rh^III and Ir^III complexes on carbon black via radical grafting. The performance of the different catalysts was assessed for the hydrosilylation of phenylacetylene with Et₃SiH. The efficiency of the catalysts was dependent on the length of the tethers to the surface. The Rh^III– and Ir^III hybrids afforded the β(Z)-vinylsilanes, as observed for the analogous homogeneous Rh^III catalyst. No distinct product selectivity was observed when using the homogeneous Rh^I precursors as catalysts. However, on using the Rh^III hybrid catalysts derived from the Rh^I precursors to promote hydrosilylation, the major products were the α-vinylsilanes and the origin of the difference in reactivity was found to be a chem. modification of the catalysts during immobilization. Substrate scope is demonstrated for a number of alkynes, and feasible mechanisms supported by DFT calculations are proposed.

Electric Literature of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl bromides undergo the Heck reaction, which involves C-C coupling with alkene to give substituted alkenes. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Methyl bromide is a precursor in the manufacture of several chemicals and is employed as a soil sterilant, mainly for seed production. Synthetic Route of 4224-70-8.

Ruffell, Katie;Smith, Frances R.;Green, Michael T.;Nicolle, Simon M.;Inman, Martyn;Lewis, William;Hayes, Christopher J.;Moody, Christopher J. research published 《 Diazophosphonates: Effective Surrogates for Diazoalkanes in Pyrazole Synthesis》, the research content is summarized as follows. Diazophosphonates, readily prepared from α-ketophosphonates by oxidation of the corresponding hydrazones in batch or in flow, are useful partners in 1,3-dipolar cycloaddition reactions to alkynes to give N-H pyrazoles, including the first intramol. examples of such a process. The phosphoryl group imbues a number of desirable properties into the diazo 1,3-dipole. The electron-withdrawing nature of the phosphoryl stabilizes the diazo compound making it easier to handle, while the ability of the phosphoryl group to migrate readily in a [1,5]-sigmatropic rearrangement enables its transfer from C to N to aromatize the initial cycloadduct, and hence its facile removal from the final pyrazole product. Overall, the diazophosphonate acts as a surrogate for the much less stable diazoalkane in cycloadditions, with the phosphoryl group playing a vital, but traceless, role. The cycloaddition proceeds more readily with alkynes bearing electron-withdrawing groups, and is regiospecific with asym. alkynes. The potential of diazophosphonates for use in bioorthogonal cycloadditions is demonstrated by their facile addition to strained alkynes.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Synthetic Route of 4224-70-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Application In Synthesis of 4224-70-8.

Qiu, Xiaqiu;Li, Yuanqing;Yu, Bin;Ren, Jie;Huang, Huidan;Wang, Min;Ding, Hong;Li, Zhiyu;Wang, Jubo;Bian, Jinlei research published 《 Discovery of selective CDK9 degraders with enhancing antiproliferative activity through PROTAC conversion》, the research content is summarized as follows. Cyclin-dependent kinase 9 (CDK9) is an increasingly important potential cancer treatment target. Nowadays, developing selective CDK9 inhibitors has been extremely challenging as its ATP-binding sites are similar with other CDKs. Here, we report that the CDK9 inhibitor BAY-1143572 is converted into a series of proteolysis targeting chimeras (PROTACs) which leads to several compounds inducing the degradation of CDK9 in acute myeloid leukemia cells at a low nanomolar concentration In addition, the most potent PROTAC mol. could inhibit cell growth more effectively than warhead alone, with little inhibition of other kinases. This enhanced antiproliferative activity is mediated by a slight increase in kinase inhibitory activity and an increase in the level of apoptosis induction. Moreover, the most potent PROTAC mol. could induce the degradation of CDK9 in vivo. Our work provides evidence that the most potent PROTAC mol. represents a lead for further development and that CDK9 degradation is a potential valuable therapeutic strategy in acute myeloid leukemia.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Application In Synthesis of 4224-70-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. COA of Formula: C6H11BrO2.

Perrone, Maria Grazia;Vitale, Paola;Miciaccia, Morena;Ferorelli, Savina;Centonze, Antonella;Solidoro, Roberta;Munzone, Cristina;Bonaccorso, Carmela;Fortuna, Cosimo Gianluca;Kleinmanns, Katrin;Bjoerge, Line;Scilimati, Antonio research published 《 Fluorochrome Selection for Imaging Intraoperative Ovarian Cancer Probes》, the research content is summarized as follows. The identification and removal of all gross and microscopic tumor to render the patient disease free represents a huge challenge in ovarian cancer treatment. The presence of residual disease is an independent neg. prognostic factor. Herein, we describe the synthesis and the “in vitro” evaluation of compounds as cyclooxygenase (COX)-1 inhibitors, the COX-1 isoform being an ovarian cancer biomarker, each bearing fluorochromes with different fluorescence features. Two of these compounds N-[4-(9-dimethylimino-9H-benzo[a]phenoxazin-5-ylamino) butyl]-2-(3,4-bis(4-methoxyphenyl)isoxazol-5-yl)acetamide chloride (RR11) and 3-(6-(4-(2-(3,4-bis(4-methoxyphenyl)isoxazole-5-yl)acetamido)butyl)amino-6-oxohexyl)-2-[7-(1,3-dihydro-1,1-dimethyl-3-Et 2H-benz[e]indolin-2-yl-idene)-1,3,5-heptatrienyl]-1,1-dimethyl-3-(6-carboxilato-hexyl)-1H-benz[e]indolium chloride, 23 (MSA14) were found to be potent and selective inhibitors of cyclooxygenase (COX)-1 “in vitro”, and thus were further investigated “in vivo”. The IC₅₀ values were 0.032 and 0.087 μM for RR11 and 23 (MSA 14), resp., whereas the COX-2 IC₅₀ for RR11 is 2.4 μM while 23 (MSA14) did not inhibit COX-2 even at a 50 μM concentration Together, this represented selectivity index = 75 and 874, resp. Structure-based virtual screening (SBVS) performed with the Fingerprints for Ligands and Proteins (FLAP) software allowed both to differentiate highly active compounds from less active and inactive structures and to define their interactions inside the substrate-binding cavity of hCOX1. Fluorescent probes RR11 and 23 (MSA14), were used for preliminary near-IR (NIR) fluorescent imaging (FLI) in human ovarian cancer (OVCAR-3 and SKOV-3) xenograft models. Surprisingly, a tumor-specific signal was observed for both tested fluorescent probes, even though this signal is not linked to the presence of COX-1.

COA of Formula: C6H11BrO2, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Safety of 6-Bromohexanoic acid.

Pan, Jun-Lin;Xu, Chu-Ran;Zeng, Fu-Rong;Liang, Yang;Zhang, Tao;Xu, Jing;Li, Zi-Long;Li, Zi-Chen research published 《 Castor Oil-Based Bioplastics via Polyesterification: Synthesis, Characterization, and Functionalization》, the research content is summarized as follows. Synthesis and application of biobased polymers are at the forefront of polymer science. Herein, we report the synthesis, characterization, and functionalization of castor oil-based bioplastics. At first, polymer P1 was synthesized via polyesterification by using monomer 11-bromoundecanoic acid (1) to demonstrate the feasibility of this step-growth polymerization method. The success of this polycondensation technique relies on the high substitution efficiency between terminal groups, carboxylic acid, and carbon-bromide moieties under alk. conditions. Subsequently, copolymers P2-P5 with varied compositions were obtained by random copolymerization of monomers 1 and 6-bromohexanoic acid (2) in different feed ratios. Linear pos. correlation is disclosed between the crystallization (T_c) and melting (T_m) temperatures of P1-P5 and the molar fraction of 1 within these specimens. Differential scanning calorimetry (DSC) and wide-angle X-ray diffraction (WAXD) results illustrate good crystallinity of these bioplastics. Furthermore, the degradation of polymers P1-P5 is propelled by an external basic environment while hindered by their intrinsic hydrophobicity, indicating that alkalinity and composition are two essential factors to manipulate the degradation behaviors of biobased polyesters in the bulk state. Ultimately, polymerization of 1 in the presence of 1-pyrenebutyric acid (3), an end-capping agent, was carried out to yield α-pyrene functionalized polymer P7. This material is capable of serving as a practical fluorescent probe and multiwalled carbon nanotube (MWNT) dispersion stabilizer. Polyesterification reported herein represents a facile and cost-effective synthetic strategy and shows great prospects in sustainable polymer materials.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Safety of 6-Bromohexanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Organic compounds having carbon bonded to bromine are called organic bromides. Product Details of C6H11BrO2.

Pang, Zeyang;Li, Qizhen;Jia, Yuexiao;Yan, Weixiao;Qi, Jie;Guo, Yuan;Hu, Fupin;Zhou, Dejian;Jiang, Xingyu research published 《 Controlling the pyridinium-zwitterionic ligand ratio on atomically precise gold nanoclusters allowing for eradicating Gram-positive drug-resistant bacteria and retaining biocompatibility》, the research content is summarized as follows. Infections caused by multidrug-resistant (MDR) bacteria are an increasing global healthcare concern. In this study, we developed a dual-ligand-functionalised Au₂₅(SR₁)_x(SR₂)_18-x-type gold nanocluster and determined its antibacterial activity against MDR bacterial strains. The pyridinium ligand (SR₁) provided bactericidal potency and the zwitterionic ligand (SR₂) enhanced the stability and biocompatibility. By optimizing the ligand ratio, our gold nanocluster could effectively kill MDR Gram-pos. bacteria via multiple antibacterial actions, including inducing bacterial aggregation, disrupting bacterial membrane integrity and potential, and generating reactive oxygen species. Moreover, combining the optimized gold nanocluster with common antibiotics could significantly enhance the antibacterial activity against MDR bacteria both in in vitro and animal models of skin infections. Furthermore, the fluorescence of the gold nanocluster at the second near-IR (NIR-II) biol. window allowed for the monitoring of its biodistribution and body clearance, which confirmed that the gold nanoclusters had good renal clearance and biocompatibility. This study provides a new strategy to combat the MDR challenge using multifunctional gold nanomaterials.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Product Details of C6H11BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, Safety of 6-Bromohexanoic acid

Nayak, Rashmi Ashwathama;Bhat, Sachin A.;Rao, D. S. Shankar;Yelamaggad, C. V. research published 《 Wide thermal range, exclusive occurrence of technically significant chiral nematic phase: synthesis and mesomorphism of cholesterol-based non-symmetric dimers》, the research content is summarized as follows. Fifteen new non-sym. chiral dimers belonging to three different series have been synthesized and evaluated for their mesomorphic properties. They were formed by interlinking cholesterol with salicylaldimine (SAN) cores (with reverse imine groups) via an ω-oxyalkanoyloxy spacer. Within a series, the length of the terminal n-alkoxy tails had been varied for a fixed even-parity spacer. Three even-parity spacers such as 4-oxybutanoyloxy, 6-oxyhexanoyloxy and 8-oxyoctanoyloxy have been used to join two cores, whereas the terminal tails such as n-butyloxy, n-hexyloxy, n-octyloxy, n-decyloxy and n-dodecyloxy chains have been attached to the SAN core. Microscopic and calorimetric exptl. results show that all the dimers behave identically exhibiting the chiral nematic (N*) phase solely, which was authenticated by powder X-ray diffraction studies carried out on some selected samples. In the vast majority of the cases,the phase was thermodynamically stable, and while cooling, it exists over a wide thermal range covering room temperature(RT)due to supercooling. Finding was notable given the fact that the N* phase possesses technol. significant optical properties. At RT, the N* phase displayed one of the iridescent colors characteristically caused by interference and diffraction of the reflected and scattered light. A comparative study reveals that the lengths of both the terminal chain and central spacer influence the clearing temperature of the dimers, and also the temperature range of the N* phase. The selective reflection measurements revealed that the pitch of the N* phase was either temperature sensitive or temperature insensitive. Temperature-dependent CD (CD) spectra were recorded for the planar texture of the N* phase formed by a dimer, as a representative case. The presence of an intense neg. CD band suggests the left-handed screw sense of the N* phase helix.

4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., Safety of 6-Bromohexanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid, Electric Literature of 4224-70-8

Ndima, Lubabalo;Hosten, Eric C.;Betz, Richard research published 《 The crystal structure of 6-bromohexanoic acid, C6H11BrO2》, the research content is summarized as follows. C6H11BrO2, monoclinic, P21/n (number 14), a = 10.6730(14) Å, b = 5.2781(6) Å, c = 14.7781(18) Å, β = 109.610(4)°, V = 784.21(17) Å3, Z = 4, Rgt(F) = 0.0225, wRref(F2) = 0.0564, T = 200(2) K.

Electric Literature of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary