Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Organic compounds having carbon bonded to bromine are called organic bromides. Product Details of C4H7BrO2.
Cooze, Morgan J.;Barr, Nathaniel R.;Hutchinson, Robin A. research published 《 Toward an Efficient Process for the Cu(0)-Mediated Synthesis and Chain Extension of Poly(methyl acrylate) Macroinitiator Using PMDETA as Ligand》, the research content is summarized as follows. Me6TREN (tris[2-(dimethylamino)ethyl]amine) is commonly used in Cu(0)-mediated polymerization of acrylates due to its ability to promote high reaction rates while maintaining excellent control of chain growth. However, its cost presents a significant barrier to commercialization. Thus, the use of PMDETA (N,N,N’,N”,N”-pentamethyldiethylenetriamine), a ligand that is significantly less expensive than Me6TREN but is known to reduce the polymerization rate as well as control, is explored. The continuous production of low mol. weight (MW) poly(Me acrylate) using PMDETA ligand in a copper tubular reactor is demonstrated, with conversions >70% achieved with a residence time of 32 min at 70°C. The resulting macroinitiator solution can be stored and chain extended with Me acrylate (MA) to high conversion in a semibatch reactor using either PMDETA or Me6TREN as addnl. ligand, increasing the versatility of a newly developed process to efficiently produce block copolymers using either ligand, or a combination of the two. First results suggest that the two-step process can also be used to chain extend the macroinitiator with methacrylates, thus extending the range of materials that can be produced.
Product Details of C4H7BrO2, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.
Referemce:
Bromide – Wikipedia,
bromide – Wiktionary