Category: 57293-19-3

Synthesis of Benzylic Alcohols by C-H Oxidation was written by Tanwar, Lalita;Boergel, Jonas;Ritter, Tobias. And the article was included in Journal of the American Chemical Society in 2019.Quality Control of 1-(3-Bromopropyl)-4-methoxybenzene This article mentions the following:

Selective methylene C-H oxidation for the synthesis of alcs. with a broad scope and functional group tolerance is challenging due to the high proclivity for further oxidation of alcs. to ketones. Here, authors report the selective synthesis of benzylic alcs. employing bis(methanesulfonyl) peroxide as an oxidant. Authors attempt to provide a rationale for the selectivity for monooxygenation, which is distinct from previous work; a proton-coupled electron transfer mechanism (PCET) may account for the difference in reactivity. Authors envision that our method will be useful for applications in the discovery of drugs and agrochems. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Quality Control of 1-(3-Bromopropyl)-4-methoxybenzene).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Quality Control of 1-(3-Bromopropyl)-4-methoxybenzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Photocatalyzed site-selective C(sp³)-H sulfonylation of toluene derivatives and cycloalkanes with inorganic sulfinates was written by Zhang, Shaonan;Cao, Shi;Lin, Yu-Mei;Sha, Liyuan;Lu, Cheng;Gong, Lei. And the article was included in Chinese Journal of Catalysis in 2022.SDS of cas: 57293-19-3 This article mentions the following:

Herein, a convenient and economic approach to site-selective C(sp3)-H sulfonylation via photo-induced HAT catalysis was reported. Employing a conjugated polycyclic quinone as a direct HAT photocatalyst, com. available inorganic sulfinates as the sulfonylation source, copper triflate as an inexpensive oxidant, a variety of toluene derivatives and cycloalkanes were converted into biol. and synthetically interesting sulfone products I [Ar = 4-MeC₆H₄, 4-EtC₆H₄, 4-MeOC₆H₄, etc.; R¹ = H, Me; R² = Me, Et, Ph, etc.; R³ = Ph, Et, i-Pr, etc.], II [R⁴ = cyclopentyl, cyclohexyl, cycloheptyl, etc.] under mild conditions. The mechanistic studies reveal that the reaction sequence involved direct HAT-induced radical formation and a subsequent copper-mediated organometallic process for the C-S bond formation. This method offered an appealing opportunity to furnish high value-added products from abundant hydrocarbon starting materials and inexpensive reagents. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3SDS of cas: 57293-19-3).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.SDS of cas: 57293-19-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of 1-aryl-tetralins and 4-aryl-benzopyrans by sulfoxide-mediated benzylic carbocation cyclizations was written by Volonterio, Alessandro;Zanda, Matteo. And the article was included in Tetrahedron Letters in 2005.Safety of 1-(3-Bromopropyl)-4-methoxybenzene This article mentions the following:

An alkylation/cyclization sequence, with both steps mediated by the ortho-N-methylformamido-phenylsulfinyl function, provided two new C-C bonds and an efficient entry to 1-aryltetralins and 4-arylbenzopyrans. Scope and limits of the process were studied in detail. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Safety of 1-(3-Bromopropyl)-4-methoxybenzene).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Safety of 1-(3-Bromopropyl)-4-methoxybenzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of S-alkylisothiuronium halides by reaction of thiourea with ω-(4-hydroxyaryl)alkyl halides was written by Kandalintseva, N. V.;Prosenko, A. E.;Dyubchenko, O. I.;Stoyanov, E. S.. And the article was included in Russian Journal of Organic Chemistry (Translation of Zhurnal Organicheskoi Khimii) in 2001.Category: bromides-buliding-blocks This article mentions the following:

A number of new S-arylalkylisothiuronium salts, e.g., I, were synthesized by reaction of ω-[4-hydroxy(methoxy)aryl]alkyl halides with thiourea. The resulting isothiuronium salts in aqueous solution react with sodium (potassium) halides to form halogen exchange products. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Category: bromides-buliding-blocks).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Scalable anti-Markovnikov hydrobromination of aliphatic and aromatic olefins was written by Galli, Marzia;Fletcher, Catherine J.;del Pozo, Marc;Goldup, Stephen M.. And the article was included in Organic & Biomolecular Chemistry in 2016.Recommanded Product: 57293-19-3 This article mentions the following:

To improve access to a key synthetic intermediate a direct hydrobromination-Negishi route was targeted. Unsurprisingly, the anti-Markovnikov addition of HBr to estragole in the presence of AIBN proved successful. However, even in the absence of an added initiator, anti-Markovnikov addition was observed Re-examination of early reports revealed that selective Markovnikov addition, often simply termed “normal” addition, was not always observed with HBr unless air was excluded, leading to the rediscovery of a reproducible and scalable initiator-free protocol. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Recommanded Product: 57293-19-3).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Recommanded Product: 57293-19-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Terminal Trifluoromethylation of Ketones via Selective C-C Cleavage of Cycloalkanols Enabled by Hypervalent Iodine Reagents was written by Wu, Shuang;Li, Junzhao;He, Ru;Jia, Kunfang;Chen, Yiyun. And the article was included in Organic Letters in 2021.Synthetic Route of C10H13BrO This article mentions the following:

The first terminal trifluoromethylation at aryl and alkyl ketone’s γ, δ, ε, or more remote sites via selective C-C bond cleavage of cycloalkanols was reported. The noncovalent interactions between alcs. and hypervalent iodines(III) reagents were disclosed to activate both alcs. and the Togni I reagent in the dual photoredox/copper catalysis for the transformation. This reaction was scalable to the gram-scale synthesis, applicable to the structurally complex steroid trifluoromethylation, and extendable to the pentafluoroethylation. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Synthetic Route of C10H13BrO).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Synthetic Route of C10H13BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

4-Alkyloxyimino Derivatives of Uridine-5′-triphosphate: Distal Modification of Potent Agonists as a Strategy for Molecular Probes of P2Y₂, P2Y₄, and P2Y₆ Receptors was written by Jayasekara, P. Suresh;Barrett, Matthew O.;Ball, Christopher B.;Brown, Kyle A.;Hammes, Eva;Balasubramanian, Ramachandran;Harden, T. Kendall;Jacobson, Kenneth A.. And the article was included in Journal of Medicinal Chemistry in 2014.Name: 1-(3-Bromopropyl)-4-methoxybenzene This article mentions the following:

Extended N⁴-(3-arylpropyl)oxy derivatives of uridine-5′-triphosphate were synthesized and potently stimulated phospholipase C stimulation in astrocytoma cells expressing G protein-coupled human (h) P2Y receptors (P2YRs) activated by UTP (P2Y_2/4R) or UDP (P2Y₆R). The potent P2Y₄R-selective N⁴-(3-phenylpropyl)oxy agonist was Ph ring-substituted or replaced with terminal heterocyclic or naphthyl rings with retention of P2YR potency. This broad tolerance for steric bulk in a distal region was not observed for dinucleoside tetraphosphate agonists with both nucleobases substituted. The potent N⁴-(3-(4-methoxyphenyl)-propyl)oxy analog I (EC₅₀: P2Y₂R, 47 nM; P2Y₄R, 23 nM) was functionalized for chain extension using click tethering of fluorophores as prosthetic groups. The BODIPY conjugate exhibited EC₅₀ values of 70, 66, and 23 nM at the hP2Y_2/4/6Rs, resp., and specifically labeled cells expressing the P2Y₆R. Thus, an extended N⁴-(3-arylpropyl)oxy group accessed a structurally permissive region on three G_q-coupled P2YRs, and potency and selectivity were modulated by distal structural changes. This freedom of substitution was utilized to design of a pan-agonist fluorescent probe of a subset of uracil nucleotide-activated hP2YRs. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Name: 1-(3-Bromopropyl)-4-methoxybenzene).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Name: 1-(3-Bromopropyl)-4-methoxybenzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Vinyl Azides as Radical Acceptors in the Vitamin B₁₂-Catalyzed Synthesis of Unsymmetrical Ketones was written by Dworakowski, Krzysztof R.;Pisarek, Sabina;Hassan, Sidra;Gryko, Dorota. And the article was included in Organic Letters in 2021.HPLC of Formula: 57293-19-3 This article mentions the following:

Vitamin B₁₂ catalyzed the reaction of vinyl azides with electrophiles under light irradiation to afforded unsym. carbonyl compounds R¹C(O)CH₂R² [R¹ = Ph, 4-t-BuC₆H₄, 4-ClC₆H₄, etc.; R² = (CH₂)₃CN, (CH₂)₃Ph, (CH₂)₃C(O)OEt, etc.] in decent yields. Mechanistic studies revealed that alkyl radicals were key intermediates in this transformation. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3HPLC of Formula: 57293-19-3).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. HPLC of Formula: 57293-19-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Highly efficient synthesis of alkylboronate esters via Cu(II)-catalyzed borylation of unactivated alkyl bromides and chlorides in air was written by Bose, Shubhankar Kumar;Brand, Simon;Omoregie, Helen Oluwatola;Haehnel, Martin;Maier, Jonathan;Bringmann, Gerhard;Marder, Todd B.. And the article was included in ACS Catalysis in 2016.Synthetic Route of C10H13BrO This article mentions the following:

A copper(II)-catalyzed borylation of alkyl halides with bis(pinacolato)diboron (B₂pin₂) has been developed, which can be carried out in air, providing a wide range of primary, secondary, and some tertiary alkylboronates in high yields. A variety of functional groups are tolerated and the protocol is also applicable to unactivated alkyl chlorides (including 1,1- and 1,2-dichlorides). Preliminary mechanistic investigations show that this borylation reaction involves one-electron processes. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Synthetic Route of C10H13BrO).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Synthetic Route of C10H13BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Lewis base-promoted carbon-carbon sp³-sp³ coupling reactions of α-silyl silylethers was written by Brekan, Jonathan A.;Chernyak, Dmitri;White, Kolby L.;Scheidt, Karl A.. And the article was included in Chemical Science in 2012.Application In Synthesis of 1-(3-Bromopropyl)-4-methoxybenzene This article mentions the following:

A Lewis base-promoted addition of α-silyl silylethers to primary halides has been developed. This new carbon-carbon sp³-sp³ bond-forming process accesses an unconventional reactivity pattern (d¹ synthon) from easily accessible precursors. The strategy accommodates a variety of primary alkyl, allylic and benzylic electrophiles and α-silyl silylethers. These d¹ synthons have also been used in the synthesis of cross pinacol and benzil products. Mechanistic studies indicate significant intermol. silyl group exchange during the reaction. In the experiment, the researchers used many compounds, for example, 1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3Application In Synthesis of 1-(3-Bromopropyl)-4-methoxybenzene).

1-(3-Bromopropyl)-4-methoxybenzene (cas: 57293-19-3) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Application In Synthesis of 1-(3-Bromopropyl)-4-methoxybenzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary