Category: 80480-15-5

Isolation of dinophysistoxin-2 and the high-performance liquid chromatographic analysis of diarrhetic shellfish toxins using derivatization with 1-bromoacetylpyrene was written by Kelly, Sean S.;Bishop, Alan G.;Carmody, Eoin P.;James, Kevin J.. And the article was included in Journal of Chromatography A in 1996.Product Details of 80480-15-5 The following contents are mentioned in the article:

The rare diarrhetic shellfish toxin, dinophysistoxin-2 (DTX-2), was isolated from the digestive glands of mussels (Mytilus edulis). This was achieved by chromatog. on silica and Sephadex LH-20 followed by reversed-phase solid phase extraction and semi-preparative high-performance liquid chromatog. (HPLC) with an Ultremex C₁₈ column. Using 1-bromoacetylpyrene (BAP), as a precolumn derivatization reagent, the diarrhetic shellfish toxins, okadaic acid (OA), dinophysistoxin-1 (DTX-1) and DTX-2, were determined by HPLC with fluorimetric detection. Derivatization using BAP was compared with 9-anthryldiazomethane (ADAM) and, although the latter exhibited a four-fold better sensitivity, the BAP method gave fewer artifact peaks from reagent decomposition The limits of detection of OA and DTX-2 were 0.4 ng on-column using BAP, which permits this method to be used for the regulatory control of these toxins in shellfish. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Product Details of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Product Details of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Rapid Identification of Bacteria by Membrane-Responsive Aggregation of a Pyrene Derivative was written by Long, Shuangshuang;Miao, Lu;Li, Ruihua;Deng, Fei;Qiao, Qinglong;Liu, Xiaogang;Yan, Aixin;Xu, Zhaochao. And the article was included in ACS Sensors in 2019.Application of 80480-15-5 The following contents are mentioned in the article:

An imidazolium-derived pyrene aggregation was developed to rapidly identify and quantify different bacteria species. When the nonemissive aggregates bound to the anionic bacteria surface, the sensor disassembled to turn on significant fluorescence. At the same time, ratiometric signals between pyrene monomer and excimer emission were controlled by different interactions with various bacteria surfaces. The resulted different fluorescent emission profiles then were obtained as fingerprints for various bacterial species. By converting emission profiles directly into output signals of two channels, fluorescence increase and ratiometric change, a two-dimensional anal. map was generated for bacteria identification. The authors demonstrated that the sensor rapidly identified 10 species of bacteria and 14 clin. isolated multidrug-resistant bacteria, and the authors determined their staining properties (Gram-pos. or Gram-neg.). This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Noncovalent functionalization of graphene with pyrene-terminated liquid crystalline polymer was written by Ji, Liangliang;Wu, Yanhong;Ma, Lijun;Yang, Xiaoming. And the article was included in Composites, Part A: Applied Science and Manufacturing in 2015.COA of Formula: C18H11BrO The following contents are mentioned in the article:

Pyrene-terminated liquid crystalline polymers, poly[8-(4-cyano-4′-biphenyl)-1-octanoylacrylate] and poly[6-(4-cyano-4′-biphenyl)-1-hexanoylacrylate] were synthesized and used to functionalize graphene sheets via π-π interactions. The resulting liquid crystalline polymers functionalized graphene sheets were characterized by UV-vis spectroscopy, fluorescence spectroscopy, thermal gravimetric anal., Fourier transform IR spectroscopy, X-ray diffraction, at. force microscopy and Raman spectroscopy. It was found that an intercalated layer structure was formed when polymer was grafted onto graphene sheets. The liquid crystalline polymers were able to effectively disperse graphene in N,N-dimethylformamide that were stable for months. Addnl., a remarkable smaller distance of adjacent mesogenic units was observed, which is attributed to the confinement of the polymer chains between 2D reduced graphene oxide sheets. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5COA of Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. COA of Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Visible-Light-Induced Passerini Multicomponent Polymerization was written by Tuten, Bryan T.;De Keer, Lies;Wiedbrauk, Sandra;Van Steenberge, Paul H. M.;D’hooge, Dagmar R.;Barner-Kowollik, Christopher. And the article was included in Angewandte Chemie, International Edition in 2019.HPLC of Formula: 80480-15-5 The following contents are mentioned in the article:

Herein, we introduce an additive-free visible-light-induced Passerini multicomponent polymerization (MCP) for the generation of high molar mass chains. In place of classical aldehydes (or ketones), highly reactive, in situ photogenerated thioaldehydes are exploited along with isocyanides and carboxylic acids. Prone to side reactions, the thioaldehyde moieties create a complex reaction environment which can be tamed by optimizing the synthetic conditions utilizing stochastic reaction path anal., highlighting the potential of semi-batch procedures. Once the complex MCP environment is understood, step-growth polymers can be synthesized under mild reaction conditions which-after a Mumm rearrangement-result in the incorporation of thioester moieties directly into the polymer backbone, leading to soft matter materials that can be degraded by straightforward aminolysis or chain expanded by thiirane insertion. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5HPLC of Formula: 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.HPLC of Formula: 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

1-(Hydroxyacetyl)pyrene a new fluorescent phototrigger for cell imaging and caging of alcohols, phenol and adenosine was written by Jana, Avijit;Saha, Biswajit;Ikbal, Mohammed;Ghosh, Sudip Kumar;Singh, N. D. Pradeep. And the article was included in Photochemical & Photobiological Sciences in 2012.Application of 80480-15-5 The following contents are mentioned in the article:

1-(Hydroxyacetyl)pyrene has been introduced as a new fluorescent phototrigger for alcs. and phenols. Alcs. and phenols were protected as their corresponding carbonate esters by coupling with fluorescent phototrigger, 1-(hydroxyacetyl)pyrene. Photophys. studies of caged carbonates showed that they all exhibited strong fluorescence properties. Irradiation of the caged carbonates by visible light (≥410 nm) in aqueous acetonitrile released the corresponding alcs. or phenols in high chem. (95-97%) and quantum (0.17-0.21) yields. The mechanism for the photorelease was proposed based on Stern-Volmer quenching experiments and solvent effect studies. Importantly, 1-(hydroxyacetyl)pyrene showed as a phototrigger for rapid photorelease of the biol. active mol. adenosine. In vitro biol. studies revealed that 1-(hydroxyacetyl)pyrene has good biocompatibility, cellular uptake property and cell imaging ability. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Application of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Improvement of chemical analysis of antibiotics. XX Basic study on high-performance liquid chromatographic determination of four polyether antibiotics pre-derivatized with 1-bromoacetylpyrene was written by Asukabe, Hirohiko;Murata, Hideaki;Harada, Ken-Ichi;Suzuki, Makoto;Oka, Hisao;Ikai, Yoshitomo. And the article was included in Journal of Chromatography A in 1993.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

A high-performance liquid chromatog. method for the determination of the polyether antibiotics (PEs), salinomycin (SL), monensin (MN), lasalocid (LA) and narasin (NA), based on a precolumn reaction system using 1-bromoacetylpyrene (1-BAP) as a fluorescence reagent, was established. Six standards of 1-pyrenacyl esters (PEs-PYs) including two of 1-pyrenacyl esters of internal standards, 18,19-dihydrosalinomycin (DSL) and 18,19-dihydro-20-ketosalinomycin (DKSL), were separated within 30 min on a Develosil 5C₁₈ (5 μm) column (250×4.6 mm I.D.) with methanol-water (97:3) as the mobile phase at a flow-rate of 1.0 mL/min and were detected at λ_ex 360 nm, λ_em 420 nm. This system was also effective for the separation between unused 1-BAP and PEs-PYs and the simultaneous determination of SL, MN, LA and NA was achieved at concentrations from 0.2 to 100 μg/mL. At concentrations of less than 10 μg/mL a silica gel cartridge was effective in eliminating the excess of unused reagents. Four calibration graphs with the internal standard method were linear between 20 and 100 μg/mL, 2 and 10 μg/mL and 0.2 and 1.0 μg/mL. The method is applicable to feed and residue analyses. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Copolymerization of n-butyl acrylate with methyl methacrylate by a novel photoinitiator, 1-(bromoacetyl)pyrene was written by Mishra, Anuradha;Daswal, Swati. And the article was included in International Journal of Chemical Kinetics in 2007.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

The photopolymerization efficiency of pyrene (Py), 1-acetylpyrene (AP), and 1-(bromoacetyl)pyrene (BP) for copolymerization of n-butylacrylate (BA) with methylmethacrylate (MMA) was compared. A kinetic study of solution copolymerization in DMSO at 30 ± 0.2° showed that the Py could not initiate copolymerization even after 20 h, whereas with AP as initiator, less than 1% conversion was observed However, introduction of a Br in α-Me group of AP significantly enhanced the percent conversion. The kinetics and mechanism of copolymerization of BA with MMA using BP as photoinitiator have been studied in detail. The system follows nonideal kinetics (R_p α |BP|^0.67|BA|¹|MMA|^0.98), and degradative solvent transfer reasonably explains these kinetic nonidealities. The monomer reactivity ratios (MRRs) of MMA and BA have been estimated by the Finemann-Ross and Kelen-Tudos methods, by analyzing copolymer compositions determined by ¹H-NMR spectra. The values of r₁ (MMA) and r₂ (BA) were found to be 2.17 and 0.44, resp., which suggested the high concentration of alternating sequences in the random copolymers obtained. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

High-performance liquid chromatographic-fluorescence determination of human fecal bile acids was written by Ikawa, Shiro;Miyake, Mariko;Mura, Tetsuo;Ikeguchi, Masahide. And the article was included in Journal of Chromatography in 1987.COA of Formula: C18H11BrO The following contents are mentioned in the article:

A HPLC method with fluorescence detection was developed for the determination of human fecal bile acids, especially free fecal bile acids. Fecal bile acids were extracted by using an Amberlite XAD-2 column and then fractionated into 4 groups (free, glycine-conjugated, taurine-conjugated, and sulfated bile acids) on a piperidinohydroxypropyl-Sephadex LH 20 column. The free bile acid fraction and free bile acids obtained after enzymic hydrolysis and/or solvolysis of the 3 other fractions were derivatized with 1-bromoacetylpyrene and dicyclohexyl-18-crown-6-ether. The derivatized bile acids were separated stepwise on a Shim-pack CLC-ODS column with MeCN-MeOH-H₂O (100:50:30) (A), (100:50:20) (B), and (100:50:0) (C) as mobile phases while changing automatically from A to C by using a solvent changer. Calibration curves of bile acid standards were linear in the range 20-400 pmol when monitored at 370 nm (excitation) and 440 nm (emission). Percent recoveries of bile acids from human feces samples were 80-95%. The method is applicable clin. and is sensitive, reliable, and useful for the detailed determination of human fecal bile acids, especially of free bile acids. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5COA of Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.COA of Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Nucleophilicity and solvent effects on the kinetics of 4-(pyren-1-yl)thiazol-2-amine interaction with 4,6-dinitrobenzofuroxan was written by El Guesmi, Nizar;Hussein, Essam M.;Asghar, Basim H.;Obaid, Rami J.;Jassas, Rabab S.;Alharbi, Ahmed;Altass, Hatem M.;Althagafi, Ismail I.;Morad, Moataz;Moussa, Ziad;Ahmed, Saleh A.. And the article was included in Arabian Journal of Chemistry in 2020.Computed Properties of C18H11BrO The following contents are mentioned in the article:

A multistep synthesis of novel pyrene-based thiazole moiety been has been realized following some synthetic challenges and complications. The chem. structure of the synthesized compound has been established on the basis of both spectroscopic and anal. tools. Its nucleophilic reactivity with 4,6-dinitrobenzofuroxan (DNBF) has been successfully studied in solution A kinetic study of the covalent electrophile/nucleophile combination of dinitrobenzofuroxan (DNBF, electrophile) and 4-(pyren-1-yl)thiazol-2-amine (nucleophile) resulting in the formation of the corresponding σ-adduct in solution is reported. The rate constant (k₁) of the second-order relating to the C-C bond forming step of this complexation process has been found to fit into the linear correlation log k = s_N (N + E), thereby permitting the evaluation of the nucleophilicity parameter (N) of the 4-(pyren-1-yl)thiazol-2-amine. 4-(Pyren-1-yl)thiazol-2-amine has been subsequently ranked according to its reactivity profile on the general nucleophilicity scale developed recently by Mayr et al., leading to an interesting and direct comparison over a large domain of π-, σ-, and n-nucleophiles. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Computed Properties of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Computed Properties of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Reaction with organic halides as a general method for the covalent functionalization of nanosheets of 2D chalcogenides and related materials was written by Manjunatha, S.;Rajesh, S.;Vishnoi, Pratap;Rao, C. N. R.. And the article was included in Journal of Materials Research in 2017.Name: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Prompted by the success in functionalizing 2D sheets of MoS₂ and MoSe₂ by their reaction with organic halides, we have investigated the functionalization of layered tungsten chalcogenides, WS₂, WSe₂, and WTe₂, by their reaction with substituted iodobenzenes as well as fluorophores based on pyrene and coumarin. Carbon-chalcogenide bonds are formed readily in the case of metallic chalcogenides while there is need for the Pd(0) catalysts in the case of insulating chalcogenides. Thus, the formation of carbon-chalcogen (S, Se, and Te) bonds is accomplished with the metallic 1T as well as the semiconducting 2H phases of the tungsten chalcogenides. Functionalization in the case of substituted iodobenzenes is favored by the electron withdrawing groups in the benzene ring. Interestingly, functionalization has been successful with other insulating layered chalcogenides such as GaS and GaSe. Reaction with organic halides emerges as a general method for the covalent functionalization of chalcogenide nanosheets, suggesting the possible use of this strategy to functionalize various chalcogenide structures. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Name: 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Name: 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary