Category: 80480-15-5

1-(Bromoacetyl)pyrene, a novel photoinitiator for the copolymerization of styrene and methyl methacrylate was written by Mishra, Anuradha;Daswal, Swati. And the article was included in Radiation Physics and Chemistry in 2006.Formula: C18H11BrO The following contents are mentioned in the article:

The photopolymerization of styrene (Sty) with Me methacrylate (MMA) induced by pyrene (Py), 1-acetylpyrene (APy) and 1-(bromoacetyl)pyrene (BrPy) was studied. Py was completely ineffective while APy could just initiate the copolymerization in 15 h. Introduction of a Br in α-Me group of APy significantly enhanced the polymerization efficiencies. The kinetics and mechanism of bulk copolymerization of Sty with MMA (Sty-co-MMA) using BrPy as a sole photoinitiator was studied in detail. The kinetic data, inhibiting effect of benzoquinone and ESR studies suggest that the polymerization proceeds via a free radical mechanism. The system follows non-ideal kinetics (R_p α[BrPy]^0·7[Sty]¹[MMA]^1·04) and degradative solvent transfer reasonably explains these kinetic non-idealities. The co-monomer reactivity ratios calculated by using the Finemann-Ross and Kelen-Tudos models were r₁ (MMA)=0.48 and r₂ (Sty)=0.52. The value of k²_p/k_t for the present system is 2.28 × 10^-5 l/mol/s. IR and NMR anal. confirms the random structure of the copolymer. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Carbon nanotube – protamine hybrid: evaluation of DNA cell penetration was written by Caoduro, Cecile;Kacem, Raoudha;Boukari, Khaoula;Picaud, Fabien;Brachais, Claire-Helene;Monchaud, David;Borg, Christophe;Boulahdour, Hatem;Gharbi, Tijani;Delage-Mourroux, Regis;Hervouet, Eric;Pudlo, Marc. And the article was included in Carbon in 2016.COA of Formula: C18H11BrO The following contents are mentioned in the article:

Carbon nanotubes (CNTs) represent a class of nanomaterials with important potential for biomedical and biotechnol. applications. CNT based vectorization is an emerging approach to the transport of nucleic acid through cell membrane but limited by detachment of DNA and degradation process. To increase DNA internalization, it was proved that cationic functionalized CNT was essential. In such a way, protamine efficiently used in several transfection processes is a cationic protein which was never associated to CNT. We propose here a novel nanovector based on single-walled carbon nanotubes (SWCNT) functionalized by protamine. Our results based on qPCR methods clearly indicate that protamine-SWCNT/DNA hybrids were much more successful than ammonium-SWCNT/DNA hybrids to cross cell membrane and penetrate into cells. We also studied the cellular internalization mechanism of our complexes and showed that endocytosis was strongly involved. Finally, we proposed mol. dynamic simulations to understand the formation of the protamine-SWCNT/DNA complex and to extract the interaction responsible for its deliverance upon cell membrane. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5COA of Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.COA of Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Fluorescence high-performance liquid chromatographic determination of free and conjugated bile acids in serum and bile using 1-bromoacetylpyrene as a prelabeling reagent was written by Kamada, Satoru;Maeda, Masako;Tsuji, Akio. And the article was included in Journal of Chromatography, Biomedical Applications in 1983.Application of 80480-15-5 The following contents are mentioned in the article:

Free and conjugated bile acids are extracted from serum or bile by using a Sep-Pak C₁₈ cartridge and then fractionated on a piperidinohydroxypropyl-Sephadex LH 20 column. Free and glycine-conjugated bile acids are labeled with 1-bromoacetylpyrene in MeCN with dicyclohexyl-18-crown-6-ether as catalyst. Taurine-conjugated bile acids are hydrolyzed by cholylglycine hydrolase and then derivatized by the same reagent. Derivatized bile acids are separated stepwise on a reversed-phase column (Radial Pak A) using MeCN-MeOH-H₂O (100:50:40) and (100:50:20) as mobile phases. The eluate is monitored by a fluorometer at 370 nm (excitation) and 440 nm (emission). Linearities of fluorescence intensities (peak heights) with the amounts of free and conjugated bile acids were obtained between 50 and 200 pmol for free bile acids and between 25 and 100 pmol for glycine-conjugated bile acids, resp. Recoveries from serum and bile samples are ≥90%. This method is sensitive, reliable, and useful for the simultaneous determination of free and conjugated bile acids in serum and bile. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Application of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

1-(Bromoacetyl)pyrene, a novel photoinitiator for the copolymerization of styrene and acrylonitrile was written by Mishra, Anuradha;Daswal, Swati. And the article was included in Colloid and Polymer Science in 2007.SDS of cas: 80480-15-5 The following contents are mentioned in the article:

A comparative study on photoinitiated solution copolymerization of Styrene (Sty), with acrylonitrile (AN) using pyrene, 1-acetylpyrene, and 1-(bromoacetyl)pyrene (BrPy) as initiators, showed that the introduction of a chromophoric moiety, bromoacetyl (-COCH₂Br), significantly increased the photoinitiating ability of pyrene. The kinetics and mechanism of copolymerization of Sty with AN (Sty-co-AN) using BrPy as photoinitiator has been studied in detail. The kinetic data, inhibiting effect of benzoquinone, and ESR (ESR) studies suggest that the polymerization proceeds via a free radical mechanism. The system followed non-ideal kinetics (R_pα[BrPy]^0.7[Sty]^1.09[AN]^1.01) and degradative solvent transfer reasonably explained these kinetic non-idealities. The co-monomer reactivity ratios calculated by using the Finemann-Ross and Kelen-Tudos models were r₁ (Sty) = 0.39 and r₂ (AN) = 0.05. The reactivity ratios strongly indicate that the 2 monomers enter in almost alternating arrangement along the copolymer chain. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5SDS of cas: 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.SDS of cas: 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Improvement of chemical analysis of antibiotics. XI. Simultaneous fluorodensitometric determination of polyether antibiotics was written by Asukabe, Hirohiko;Yoneyama, Hiromi;Mori, Yuji;Harada, Kenichi;Suzuki, Makoto;Oka, Hisao. And the article was included in Journal of Chromatography in 1987.Computed Properties of C18H11BrO The following contents are mentioned in the article:

A simultaneous determination of three polyether antibiotics, salinomycin, monensin and lasalocid, was established by silica gel and RP-18 high-performance TLC (HPTLC) using 18,19-dihydrosalinomycin and 18,19-dihydro-20-ketosalinomycin as internal standards Fluorescent derivatives of the polyethers were prepared by reaction of their Na salts with 1-bromoacetylpyrene and Kryptofix 222 in MeCN. A silica gel HPTLC plate with CCl₄-EtOAc-MeCN (50:5:10) as a solvent system and a RP-18 HPTLC plate with EtOAc-MeCN-acetone-MeCN (15:2:1:55) gave satisfactory separations of the 5 pyrenacyl esters of salinomycin, monensin, lasalocid, 18,19-dihydrosalinomycin and 18,19-dihydro-20-ketosalinomycin. Under these conditions, the internal standard 18,19-dihydrosalinomycin was suitable for the simultaneous stimulation determination of salinomycin and monensin, and 18,19-dihydro-20-ketosalinomycin for lasalocid. A linear relationship was obtained between the fluorescence intensity and the amount of each antibiotic in the range 2-14 pg. The detection limit of the 3 antibiotics was 100 pg. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Computed Properties of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Computed Properties of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Indolizine-Squaraines: NIR Fluorescent Materials with Molecularly Engineered Stokes Shifts was written by McNamara, Louis E.;Rill, Tana A.;Huckaba, Aron J.;Ganeshraj, Vigneshraja;Gayton, Jacqueline;Nelson, Rachael A.;Sharpe, Emily Anne;Dass, Amala;Hammer, Nathan I.;Delcamp, Jared H.. And the article was included in Chemistry – A European Journal in 2017.SDS of cas: 80480-15-5 The following contents are mentioned in the article:

The development of deep red and near IR emissive materials with high quantum yields is an important challenge. Several classes of squaraine dyes have demonstrated high quantum yields, but require significantly red-shifted absorptions to access the NIR window. Addnl., squaraine dyes have typically shown narrow Stokes shifts, which limits their use in living biol. imaging applications due to dye emission interference with the light source. Through the incorporation of indolizine heterocycles we have synthesized novel indolizine squaraine dyes with increased Stokes shifts (up to >0.119 eV, >50 nm increase) and absorptions substantially further into the NIR region than an indoline squaraine benchmark (726 nm vs. 659 nm absorption maxima). These materials have shown significantly enhanced water solubility, which is unique for squaraine dyes without water-solubilizing substituents. Absorption, electrochem., computational, and fluorescence studies were undertaken and exceptional fluorescence quantum yields of up 12 % were observed with emission curves extending beyond 850 nm. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5SDS of cas: 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.SDS of cas: 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis, Antimicrobial Activity and Molecular Docking Studies of 1,3-Thiazole Derivatives Incorporating Adamantanyl Moiety was written by Laczkowski, K. Z.;Misiura, K.;Biernasiuk, A.;Malm, A.;Paneth, A.;Plech, T.. And the article was included in Journal of Heterocyclic Chemistry in 2016.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

Synthesis, characterization and study of antimicrobial activity of 11 novel adamantanyl-thiazoles are presented. Their structures were determined using ¹H and ¹³C NMR, EI(+)-MS, HRMS, and elemental analyses. Among the derivatives, compound showed very strong activity, especially against Candida albicans ATCC 10231 and Candida parapsilosis ATCC 22019 with minimal inhibitory concentration (MIC) values ranging from 1.95 to 7.81 μg/mL. Compounds and showed good antifungal activity. Among the examined compounds, the widest spectrum of antibacterial activity possessed that showed good activity, especially against Staphylococcus epidermidis ATCC 12228, Micrococcus luteus ATCC 10240, Bacillus subtilis ATCC 6633 with MIC values ranging from 31.25 to 62.5 μg/mL. Mol. docking studies of all compounds on the active sites of microbial enzymes indicated possible targets sterol 14α-demethylase, secreted aspartic proteinase (SAP), N-myristoyltransferase (NMT), and topoisomerase II. Thiazoles showed more favorable affinity to SAP and NMT than the native ligand. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Copolymerization of n-butyl acrylate with styrene by a novel photoinitiator, 1-(bromoacetyl)pyrene was written by Mishra, Anuradha;Daswal, Swati. And the article was included in Journal of Applied Polymer Science in 2006.Application In Synthesis of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

A comparative study on photoinitiated solution copolymerization of Bu acrylate (BA) with styrene (Sty) using pyrene (Py), 1-acetylpyrene (AP), and 1-(bromoacetyl)pyrene (BP) as initiators showed that the introduction of a chromophoric moiety, bromoacetyl (-COCH₂Br), significantly increased the photoinitiating ability of pyrene. The kinetics and mechanism of copolymerization of BA with Sty using BP as photoinitiator have been studied in detail. The system follows nonideal kinetics (R_p ∝ [BP]^0.34 [BA]^1.07 [Sty]^0.97). The nonideality was attributed to both primary radical termination and degradative initiator transfer. The monomer reactivity ratios of Sty and BA have been estimated by the Finemann-Ross and Kelen-Tudos methods, by analyzing copolymer compositions determined by ¹H NMR spectra. The values of r₁ (Sty) and r₂ (BA) were found to be 0.78 and 0.25, resp., which suggested the high concentration of alternating sequences in the random copolymers obtained. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application In Synthesis of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Application In Synthesis of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis and properties of amphipathic fluorescent dye derived from spiculisporic acid anhydride was written by Ishigami, Yutaka;Gama, Yasuo;Matsuzaki, Sanae. And the article was included in Shikizai Kyokaishi in 1991.Formula: C18H11BrO The following contents are mentioned in the article:

The 1-pyrenecarbonylmethyl ester (I) of spiculisporic acid anhydride was synthesized as an amphipathic fluorescent probe from a microbial biosurfactant. I was synthesized by the reaction of spiculisporic acid anhydride, which was derived from spiculisporic acid, with 1-(bromoacetyl)pyrene. I showed different fluorescent spectra by behaving as “fingerprints” in response to various kinds of hydrophobic environments of solvents, mol. aggregates, and liposomes. I gave different fluorescent patterns in solvents depending on the solubility parameter. Excimer formation of I was accelerated in larger micellar domains of heptaoxyethylene dodecyl ether than in SDS. The dependence of the spectrum on surfactant concentrations was also notable. I was considered to have a larger membrane fluidity in liposomal bilayers than in micelles from the different emitting wavelengths of the resp. excimers in liposomes (511 nm) and micelles (440 or 453 nm). This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Improvement on sample clean-up for high-performance liquid chromatographic-fluorimetric determination of diarrhetic shellfish toxins using 1-bromoacetylpyrene was written by Gonzalez, Jose C.;Vieytes, Mercedes R.;Vieites, Juan M.;Botana, Luis M.. And the article was included in Journal of Chromatography A in 1998.Electric Literature of C18H11BrO The following contents are mentioned in the article:

Okadaic acid (OA) and dinophysistoxin-2, two of the main diarrhetic shellfish toxins, can be determined by high-performance liquid chromatog. coupled to fluorimetry as pyrenacyl esters. Toxin fluorescent derivatives were obtained after quant. derivatization with 1-bromoacetylpyrene in acetonitrile. An efficient improvement in the silica gel clean-up procedure of the pyrenacyl derivatives is reported. The clean-up cartridge is washed with hexane-dichloromethane (1:1, volume/volume), dichloromethane-Et acetate (8:2, volume/volume), and finally the pyrenacyl esters were eluted with dichloromethane-methanol (9:1, volume/volume). The authors compare this procedure with other methods already described. Good results were obtained with mussels, scallops and clams. The clean-up procedure showed good robustness when checked against silica and solvents activity. Using samples of mussel hepatopancreas with an OA concentration ranging from 0 to 2 μg OA/g hepatopancreas, the inter-assay relative standard deviation ranged from 5.5 to 12.6. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Electric Literature of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Electric Literature of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary