Category: 80480-15-5

Quantification of lipopeptides using high-performance liquid chromatography with fluorescence detection after derivation was written by Meng, Yong;Liu, Jin-Feng;Yang, Shi-Zhong;Ye, Ru-Qiang;Mu, Bo-Zhong. And the article was included in Analytical Sciences in 2015.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

A highly sensitive and selective high-performance liquid chromatog. (HPLC) method has been developed for the determination of microbial lipopeptides of fluorescent derivatization with 1-bromoacetylpyrene to overcome the limitations of trace detection of lipopeptides in aqueous solutions The derivatization of lipopeptides with 1-bromoacetylpyrene was conducted at 60°C for 20 min under catalysis of triethylarnine. The resulting derivative products were separated by HPLC and determined by a fluorescence detector. Each homolog of lipopeptides in samples was identified by HPLC-MS and the detection limit after derivatization in an aqueous solution was 2.5 μg/mL (S/N = 3), The calibration curve for lipopeptides was linear in the concentration range of 0.250 – 4.00 mg/mL. This method has adequate sensitivity and selectivity for microdetection of lipopeptides in aqueous solutions in mild reaction conditions, which allows this method to be used in the determination of trace lipopeptides in environmental samples and complex samples. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

1-Acetylpyrene-Salicylic Acid: Photoresponsive Fluorescent Organic Nanoparticles for the Regulated Release of a Natural Antimicrobial Compound, Salicylic Acid was written by Barman, Shrabani;Mukhopadhyay, Sourav K.;Behara, Krishna Kalyani;Dey, Satyahari;Singh, N. D. Pradeep. And the article was included in ACS Applied Materials & Interfaces in 2014.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

Photoresponsive 1-acetylpyrene-salicylic acid (AcPy-SA) nanoparticles (NPs) were developed for the regulated release of a natural antimicrobial compound, salicylic acid. The strong fluorescent properties of AcPy-SA NPs have been extensively used for potential in vitro cell imaging. The phototrigger capability of our newly prepared AcPy-SA NPs was utilized for the efficient release of an antimicrobial compound, salicylic acid. The photoregulated drug release of AcPy-SA NPs has been shown by the subsequent switching off and on of a visible-light source. In vitro biol. studies reveal that AcPy-SA NPs of ∼68 nm size deliver the antimicrobial drug salicylic acid into the bacteria cells (Pseudomonas aeruginosa) and efficiently kill the cells upon exposure to visible light (≥410 nm). Such photoresponsive fluorescent organic NPs will be highly beneficial for targeted and regulated antimicrobial drug release because of their biocompatible nature, efficient cellular uptake, and light-induced drug release ability. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A pyrene thiazole conjugate as a ratiometric chemosensor with high selectivity and sensitivity for tin (Sn⁴⁺) and its application in imaging live cells was written by Mahapatra, Ajit Kumar;Mondal, Sanchita;Maiti, Kalipada;Manna, Saikat Kumar;Maji, Rajkishor;Mandal, Debasish;Mandal, Sukhendu;Goswami, Shyamaprosad;Quah, Ching Kheng;Fun, Hoong-Kun. And the article was included in RSC Advances in 2014.Related Products of 80480-15-5 The following contents are mentioned in the article:

A new pyrene thiazole conjugate (PTC) amine fluoroionophore was synthesized and characterized. The single crystal XRD structure of PTC has been established. The fluoroionophore PTC showed selectivity toward Sn⁴⁺ by switching on ratiometric fluorescence among the 16 metal ions studied in HEPES buffer medium with a detection limit of 6.93μM. The interaction of Sn⁴⁺ with PTC has been further supported by absorption studies, and the stoichiometry of the complex formed (2:1) has been established on the basis of fluorescence and ESI-MS. Competitive ion titrations carried out reveal that the Sn⁴⁺ can be detected even in the presence of other metal ions of bio-importance. Moreover, the utility of the fluoroionophore PTC in showing the tin recognition in live cells has also been demonstrated using Vero 76 cells as monitored by fluorescence imaging. The tin complex of PTC was isolated, and the structure and electronic properties of [PTC-Sn] has been established by DFT and TDDFT calculations The isolated tin complex [PTC-Sn] has been used as a mol. tool for the recognition of anions on the basis of their binding affinities toward Sn⁴⁺. [PTC-Sn] is sensitive and selective toward sulfide ions among the other 12 anions studied. The selectivity has been shown on the basis of the changes observed in the emission and absorption spectral studies through the removal of Sn⁴⁺ from [PTC-Sn] by S^2-. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Related Products of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Related Products of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Enhancing the reinforcing efficiency in CNT nanocomposites via the development of pyrene-based active dispersants was written by Yin, Xinyi;Li, Qiang;Wang, Haishui;Yang, Wengang;Zhou, Xi;Zhang, Han;Lyu, Weibang. And the article was included in RSC Advances in 2021.Quality Control of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Various preforms of carbon nanotubes (CNTs), such as fibers, yarns, or buckypapers (BP), have been developed over the last few years in order to fabricate advanced nanocomposites containing a high volume fraction of the reinforcing phase. However, a homogeneous dispersion and an even isolation of CNTs during the fabrication process of many preforms such as BP is often challenging, while the poor interaction between CNTs and the matrix also limits the final performance of the nanocomposites. Herein, a new route to overcome these two challenges simultaneously has been demonstrated based on an active dispersant (noted as Py-PEI) developed through the quaternization reaction of pyrene derivatives (Py-Br) and polyethylenimine (PEI). The existence of pyrene groups leads to the formation of π-π stacking with CNTs, successfully hindering the re-aggregation of dispersed CNTs. Meanwhile, the amine groups of Py-PEI can establish covalent bonds with epoxy, leading to an enhanced load transfer efficiency between CNTs and epoxy in the composites. Systematic characterization of both fabricated BP and BP-reinforced nanocomposites have been performed, with significantly enhanced CNT dispersion stability in water together with improved mech. performance of the as-obtained BP/epoxy nanocomposites. This study provides a new strategy in fabricating high performance nanocomposites with the ease of nanofiller dispersion and enhanced reinforcing efficiency. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Quality Control of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Quality Control of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Soft Ultraviolet (UV) Photopatterning and Metallization of Self-Assembled Monolayers (SAMs) Formed from the Lipoic Acid Ester of α-Hydroxy-1-acetylpyrene: The Generality of Acid-Catalyzed Removal of Thiol-on-Gold SAMs using Soft UV Light was written by Pukenas, Laurynas;Prompinit, Panida;Nishitha, Boda;Tate, Daniel J.;Singh, N. D. Pradeep;Walti, Christoph;Evans, Stephen D.;Bushby, Richard J.. And the article was included in ACS Applied Materials & Interfaces in 2017.Related Products of 80480-15-5 The following contents are mentioned in the article:

Under a layer of 0.1 M HCl in isopropanol, soft UV (365 nm) photolysis of the thiol-on-gold self-assembled monolayer (SAM) derived from the lipoic acid ester of α-hydroxy-1-acetylpyrene results in the expected removal of the acetylpyrene protecting group. When photolyzing through a mask, this can be used to produce a patterned surface and, at a controlled electrochem. potential, it is then possible to selectively and reversibly electrodeposit copper on the photolyzed regions. Rather surprisingly, under these photolysis conditions, there is not only the expected photodeprotection of the ester but also partial removal of the lipoic acid layer which has been formed. In further studies, it is shown that this type of acid-catalyzed photoremoval of SAM layers by soft UV is a rather general phenomenon and results in the partial removal of the thiol-on-gold SAM layers derived from other ω-thiolated carboxylic acids. However, this phenomenon is chain-length dependent. Under conditions in which there is a ∼60% reduction in the thickness of the SAM derived from dithiobutyric acid, the SAM derived from mercaptoundecanoic acid is almost unaffected. The process by which the shorter-chain SAM layers are partially removed is not fully understood because these compounds do not absorb significantly in the 365 nm region of the spectrum! Significantly, this study shows that acid catalysis photolysis of thiol-on-gold SAMs needs to be used with caution. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Related Products of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Related Products of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Pyrene-imidazole conjugate as a fluorescent sensor for the sequential detection of iron(III) and histidine in aqueous solution was written by Wang, Jing;Jiang, Huihui;Liu, Hai-Bo;Liang, Lebao;Tao, Junrong. And the article was included in Spectrochimica Acta in 2020.COA of Formula: C18H11BrO The following contents are mentioned in the article:

We developed PIM (I), a pyrene-based fluorescence sensor bearing an imidazole moiety and a carbonyl group as the binding sites for Fe³⁺ ions. The pyrene-based control compounds 1 and 2 were synthesized to demonstrate the structure-activity relationships. Compound 1 (II), which contained a thiazoline moiety and a carbonyl group, displayed high selectivity for Cu²⁺ ions. This property indicated that heterocycles play an important role in the metal ion selectivity modulation. Compound 2 (III), which lacked a carbonyl group, did not display metal ion selectivity. This characteristic demonstrated that introducing an addnl. recognition unit (cooperative recognition strategy) should be an effective way to improve metal ion selectivity. Furthermore, the PIM-Fe³⁺ ensemble can serve as a fluorescent sensor for histidine (His) detection via the removal of Fe³⁺ from the ensemble by His and the release of PIM. The sequential detection of Fe³⁺ and His exhibited on-off-on phenomenon, and the Fe³⁺ and His detection limits were 0.11 and 3.06 μM, resp. These results will help in the further enhancement or modulation of metal ion selectivity in the development of fluorescent sensor systems. Moreover, the organic-metal ensemble provides an effective platform for detecting amino acids through the displacement strategy. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5COA of Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.COA of Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Covalent functionalization of nanosheets of MoS₂ and MoSe₂ by substituted benzenes and other organic molecules was written by Vishnoi, Pratap;Sampath, Archana;Waghmare, Umesh V.;Rao, C. N. R.. And the article was included in Chemistry – A European Journal in 2017.Safety of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Covalent functionalization has been effectively employed to attach benzene functionalities to MoS₂ and MoSe₂ nanosheets by the reaction with para-substituted iodobenzenes bearing -OCH₃, -H, and -NO₂ as the substituents, where the electron-donating and electron-withdrawing power of the para substituent varies significantly. The functionalization is based on the formation of a C-S or C-Se linkage at the expense of the C-I bond on reaction of the iodobenzene with electron-rich 1T-MoS₂ or 1T-MoSe₂. The degree of functionalization is in the range 4-24 % range, the value increases with the electron-withdrawing power of the para substituent. Semiconducting 2H-MoS₂ and 2H-MoSe₂ nanosheets can also be functionalized with iodobenzene by carrying out the reaction in the presence of a Pd⁰ catalyst. We have also carried out functionalization of 1T-MoS₂ with pyrene, coumarin, and porphyrin derivatives By using first-principles d. functional calculations, we show that the bonding of the functional groups with the 1T phase is stronger than with the 2H phase. This is reflected in notable changes in the electronic structure of the former upon functionalization; a gap opens up in the electronic spectrum of the 1T phase. Functionalization with para-substituted benzenes leads to a change in the work function. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Safety of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Safety of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Direct in situ labeling of target drugs with a fluorophore probe to improve MALDI-MS detection sensitivity in micro-liter plasma was written by Li, Yi-Shan;Lu, Chi-Yu. And the article was included in Scientific Reports in 2019.Formula: C18H11BrO The following contents are mentioned in the article:

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for symptomatic relief from fever, inflammation, and chronic pain associated with a variety of human disorders. Long-term usage of these drugs can result in severe syndromes; hence, their dose should be controlled carefully and their side effects such as Stevens-Johnson syndrome, toxic epidermal necrolysis, phototoxicity, acute interstitial nephritis, gastrointestinal bleeding, cardiovascular diseases, and liver injury should be considered. Furthermore, the widely used combination of NSAIDs as over-the-counter (OTC) drugs with other drugs leads to adverse drug-drug interactions. Therefore, development of a throughput method to rapidly screen 20 NSAIDs in biol. samples is necessary to safeguard human health. In this work, we selected a suitable fluorophore probe coupled with in situ micro-labeling (<2 min) on stainless plate for the fast detection of NSAIDs in plasma samples at the micro-liter level (5μL) without complicated sample preparation and separation Every step undertaken in the protocol was also at the micro-liter level; thus, a small amount of blood collected from the human finger will suffice to determine the drug concentration in blood using the proposed method. Furthermore, the proposed method we developed was also matched the modern trends of green anal. chem. towards miniaturization of anal. methodologies. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Rhodium-Catalyzed C-H Activation of Phenacyl Ammonium Salts Assisted by an Oxidizing C-N Bond: A Combination of Experimental and Theoretical Studies was written by Yu, Songjie;Liu, Song;Lan, Yu;Wan, Boshun;Li, Xingwei. And the article was included in Journal of the American Chemical Society in 2015.SDS of cas: 80480-15-5 The following contents are mentioned in the article:

Rh(III)-catalyzed C-H activation assisted by an oxidizing directing group has evolved to a mild and redox-economic strategy for the construction of heterocycles. Despite the success, these coupling systems are currently limited to cleavage of an oxidizing N-O or N-N bond. Cleavage of an oxidizing C-N bond, which allows for complementary carbocycle synthesis, is unprecedented. α-Ammonium acetophenones with an oxidizing C-N bond were designed as substrates for Rh(III)-catalyzed C-H activation under redox-neutral conditions. The coupling with α-diazo esters afforded benzocyclopentanones, and the coupling with unactivated alkenes such as styrenes and aliphatic olefins gave ortho-olefinated acetophenoes. In both systems the reactions proceeded with a broad scope, high efficiency, and functional group tolerance. Also, efficient 1-pot coupling of diazo esters was realized starting from α-bromoacetophenones and triethylamine. The reaction mechanism for the coupling with diazo esters was studied by a combination of exptl. and theor. methods. In particular, three distinct mechanistic pathways were scrutinized by DFT studies, which revealed that the C-H activation occurs via a C-bound enolate-assisted concerted metalation-deprotonation mechanism and is rate-limiting. In subsequent C-C formation steps, the lowest energy pathway involves two rhodium carbene species as key intermediates. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5SDS of cas: 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.SDS of cas: 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The effect of iron catalyzed graphitization on the textural properties of carbonized cellulose: Magnetically separable graphitic carbon bodies for catalysis and remediation was written by Hoekstra, Jacco;Beale, Andrew M.;Soulimani, Fouad;Versluijs-Helder, Marjan;van de Kleut, Dirk;Koelewijn, Jacobus M.;Geus, John W.;Jenneskens, Leonardus W.. And the article was included in Carbon in 2016.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Whereas pyrolysis of pristine microcrystalline cellulose spheres yields nonporous amorphous carbon bodies, pyrolysis of microcrystalline cellulose spheres loaded with iron salts leads to the formation of magnetically separable mesoporous graphitic carbon bodies. The microcrystalline cellulose spheres loaded with either iron(III) nitrate, ammonium iron(III) citrate or iron(III) chloride were pyrolyzed up to 800°. Temperature dependent x-ray diffraction anal. shows that the iron salts are transformed into iron oxide nanoparticles; their size and distribution are influenced by the anion of the iron salt. The iron oxide nanoparticles are subsequently carbothermally reduced by the amorphous carbon that is obtained from the pyrolysis of the microcrystalline cellulose. Next, the iron nanoparticles catalyze the conversion of the amorphous carbon to graphitic carbon nanostructures as shown with x-ray diffraction, electron microscopy and Raman spectroscopy. The extent of graphitization depends on the iron nanoparticle size. Nitrogen physisorption measurements show that this graphitization process introduces mesopores into the carbon bodies. The benefits of the properties of the resulting carbon bodies (ferromagnetic character, graphitic content, mesoporosity) are discussed in connection with applications in liquid-phase catalysis and remediation. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary