Category: bromides-buliding-blocks

Li, Qing published the artcileSynthesis and characterization of thieno[3,4-b]pyrazine materials for solution-processible organic red light-emitting diodes, Product Details of C4Br2N2O4S, the publication is Chemistry Letters (2011), 40(4), 417-419, database is CAplus.

Two novel thieno[3,4-b]pyrazine-cored mols., P-DTP and TP-DTP, are synthesized and are characterized by extra large Stokes shifts of over 300 nm. The bulky polyaromatic arms enable these mols. to be solution processible and provide site-isolation on the planar emissive core. They exhibit saturated red electroluminescence in non-oped organic light-emitting diodes fabricated by spin coating.

Chemistry Letters published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Product Details of C4Br2N2O4S.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Lv, You published the artcileSynthesis, crystal structure and fungicidal activity of 3-chloro-4-(3,4-dichloroisothiazol-5-yl)-5-hydroxy-7-methyl-2H-chromen-2-ones, SDS of cas: 401-55-8, the publication is Chinese Journal of Structural Chemistry (2021), 40(8), 1068-1074, database is CAplus.

3-Chloro-4-(3,4-dichloroisothiazol-5-yl)-5-hydroxy-7-methyl-2H-chromen-2-ones I [R = H, Me, Et, F, Cl] coumarin derivatives, were synthesized by β-ketoester formation and cyclization. Target compound I [R = Cl] was crystallized from methanol for structural identification as monoclinic crystal system, space group C2/c with a = 16.2700(6), b = 7.1801(5), c = 23.4861(10) Å, V = 2742.6(2) Å3, Z = 8, Dc = 1.756 g/cm3, F(000) = 1456 and μ = 0.827 mm-1. 8308 Reflections were collected (6.01≤2θ≤50.05°), of which 2428 were unique (Rint = 0.0432) and used in all calculations The final R = 0.0408 (I > 2σ(I)) and wR = 0.1056 (reflections). In-vitro bioassay indicated that compounds I [R = F, Cl] possessed good activity against Botrytis cinerea, Physalospora piricola, Rhizoctonia solani, and Sclerotinia sclerotiorum with lower EC₅₀ values falling between 0.50 and 4.85μg/mL than that of pos. control osthole with its EC₅₀ values between 7.38 and 74.59μg/mL. In-vivo screening showed that I [R = Cl] exhibited 98% and 95% efficacy against Pseudoperonospora cubensis (Berk. & Curt.) Rostov. at 100 and 50μg/mL, resp. These studies observed that the combination of bioactive substructures of isothiazole with coumarin were an effective way to novel fungicide development.

Chinese Journal of Structural Chemistry published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, SDS of cas: 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Lv, You published the artcileDesign, synthesis and fungicidal activity of 3,4-dichloroisothiazolocoumarin-containing strobilurins, SDS of cas: 401-55-8, the publication is Molecular Diversity (2022), 26(2), 951-961, database is CAplus and MEDLINE.

Twenty-one novel 3,4-dichloroisothiazolocoumarin-containing strobilurins I (R¹ = H, F, Cl, Me, Et; R² = H, 6-Me, 8-Me, 8-Cl), II were rationally designed and synthesized. Preliminary bioassay showed that compounds I (R¹ = H, R² = 8-Cl (III); R¹ = Cl, R² = 6-Me; R¹ = Me, R² = 6-Me) exhibited over 80% inhibitory rate against Sclerotinia sclerotiorum at 50μg/mL, compound III exhibited good activity against S. sclerotiorum with median effective concentration (EC₅₀) of 4.08μ/mL, while the pos. control coumoxystrobin showed EC₅₀ of 1.00μg/mL. In addition, compound I (R¹ = H, R² = 6-Me) showed better fungicidal activity with a lower EC₅₀ value of 7.65μg/mL against Botrytis cinerea than that of pos. control trifloxystrobin with its EC₅₀ value of 21.96μg/mL. In this study, it was indicated that 3,4-dichloroisothiazolocoumarin-containing strobilurins I, II were promising fungicide lead deserved for further study.

Molecular Diversity published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, SDS of cas: 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kuznetsova, Darya A. published the artcileCationic Imidazolium Amphiphiles Bearing a Methoxyphenyl Fragment: Synthesis, Self-Assembly Behavior, and Antimicrobial Activity, Recommanded Product: 1-Bromododecane, the publication is Langmuir (2022), 38(16), 4921-4934, database is CAplus and MEDLINE.

Novel cationic amphiphiles of the 3-alkyl-1-(4-methoxyphenyl)-1H-imidazol-3-ium bromide series bearing methoxyphenyl fragments (MPI-n) have been synthesized. Their aggregation properties in aqueous solutions, solubilization capacity, and hemolytic and antimicrobial activities have been investigated by a number of physicochem. methods. Using tensiometry, conductometry, and fluorescence spectroscopy, it was shown that the MPI-n have lower CMCs than their nonfunctionalized counterparts. The unusual alkyl-chain-length-dependent morphol. of aggregates is testified for this homol. series. Amphiphiles with 12, 14, and 16 alkyl tails are characterized by the formation of micellar aggregates, while a surfactant with a decyl tail is characterized by the formation of larger aggregates with lower surface curvature. The MPI-10 aggregate morphol. was rationalized in terms of the packing parameter consideration and was supported by size measurements and the fluorescence probe techniques, which showed that vesicle-like aggregates in close-packing mode probably occur. MPI-n aggregates have exhibited a high solubilization capacity toward hydrophobic azo dye Orange OT. Importantly, amphiphiles studied showed (i) high bacteriostatic activity at the level of ciprofloxacin; (ii) high bactericidal action against all Gram-pos. bacteria, including methicillin-resistant strains; (iii) bactericidal properties against Gram-neg. bacteria; and (iv) low hemolytic activity.

Langmuir published new progress about 143-15-7. 143-15-7 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromododecane, and the molecular formula is C12H25Br, Recommanded Product: 1-Bromododecane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kuznetsova, Lidia I. published the artcileOxidative Bromination of Alkenes Mediated with Nitrite in Ionic Liquids, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane, the publication is Catalysis Letters (2014), 144(9), 1499-1506, database is CAplus.

An oxidative bromination of C₂-C₈ alkenes with HBr-NaNO₂-O₂ in solutions of BMImBr, HMImBr or BMImBF₄ containing 16-28 wt% H₂O was studied using a volumetric method, GC-MS anal., ¹⁴N NMR and UV-VIS spectroscopy. The optimal conditions to conduct the reaction at high selectivity for 1,2-dibromoalkanes in BMImBr were determined The composition of ionic liquid affects the catalytic performance. Although in BMImBF₄ the reaction runs with equal rate as in bromide ionic liquid, the fraction of bromohydrin in the reaction products increases to 20%. Generated from NaNO₂, NO_x operated as a catalyst in the oxidation of bromide ion (Br^–) and was oxidized to catalytically inert nitrate (NO₃^–) anions when complete conversion of HBr was attained. The synthesis of the target compounds was achieved using 1-butyl-3-methylimidazolium bromide as ionic liquid Alkenes included 1-propene, 1-butene (α-alkenes), 2-methyl-1-propene, cyclohexene, 1-octene, 2,3-dimethyl-2-butene. The title compounds thus formed included 1,2-dibromopropane, 1,2-dibromobutane, 1,2-dibromo-2-methylpropane and similar substances. Alcs., such as 1-bromo-2-propanol, 1-bromo-2-butanol, 1-bromo-2-methyl-2-propanol, 2-bromocyclohexanol, 1-bromo-2-octanol, 2-bromoethanol were also observed Formation of 2,3-dimethyl-2,3-dinitrobutane and 2,2,3,3-tetramethyloxirane was reported.

Catalysis Letters published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Recommanded Product: 2,3-Dibromo-2,3-dimethylbutane.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Levitz, Andrew published the artcileSynthesis and effect of heterocycle modification on the spectroscopic properties of a series of unsymmetrical trimethine cyanine dyes, Name: Sodium 3-bromopropane-1-sulfonate, the publication is Dyes and Pigments (2014), 238-249, database is CAplus.

Carbocyanine dyes are a class of organic compounds that contain two heterocycles that act as electron donors and acceptors connected by a conjugated methine bridge. Herein the synthesis of a series of 16 novel unsym. trimethine cyanine dyes is reported. Their structures were characterized by various spectroscopic techniques, and their optical properties were measured. Absorption maxima of the dyes were calculated using the time-dependent d.-functional theory method and the computational absorption maxima are consistent with the exptl. data. The addition of electron withdrawing substituents such as halogens on the heterocycle gave more favorable optical properties such as higher quantum yield and molar absorptivity. The aggregation of these cyanine dyes was studied and compared to a similar series of sym. cyanine dyes. It was determined that the heterocycle has more effect on aggregation than the side chain and a dye with two different heterocycles will aggregate less than a dye with the same heterocycle. The dyes were also investigated for Lipinski Rule violations as their use is becoming more prevalent for in vivo applications.

Dyes and Pigments published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Name: Sodium 3-bromopropane-1-sulfonate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Armstrong, Megan K. published the artcileDifferential Dihydrofunctionalization of Terminal Alkynes: Synthesis of Benzylic Alkyl Boronates through Reductive Three-Component Coupling, Formula: C7H11Br, the publication is Journal of the American Chemical Society (2019), 141(15), 6173-6179, database is CAplus and MEDLINE.

The differential dihydrofunctionalization of terminal alkynes is accomplished through the reductive three-component coupling of terminal alkynes, aryl halides, and pinacolborane. The transformation results in hydrofunctionalization of both π-bonds of an alkyne in a single reaction promoted by cooperative action of a Cu/Pd catalyst system. The differential dihydrofunctionalization reaction has excellent substrate scope and can be accomplished in the presence of esters, nitriles, alkyl halides, epoxides, acetals, alkenes, aryl halides, and silyl ethers. Mechanistic experiments indicate that the reaction proceeds through Cu-catalyzed hydroboration followed by a 2nd hydrocupration. The resulting heterobimetallic complex is the key intermediate that participates in the subsequent Pd-catalyzed cross-coupling, which furnishes benzylic alkyl boronate products.

Journal of the American Chemical Society published new progress about 81216-14-0. 81216-14-0 belongs to bromides-buliding-blocks, auxiliary class Linker,PROTAC Linker, name is 7-Bromohept-1-yne, and the molecular formula is C7H11Br, Formula: C7H11Br.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Cleveland, Forrest F. published the artcileSubstituted ethanes. II. Raman and infrared spectra of 2,3-dibromo-2,3-dimethylbutane, 2,2,3,3-tetramethylbutane, Product Details of C6H12Br2, the publication is Journal of Chemical Physics (1950), 1320-4, database is CAplus.

cf. C.A. 39, 2254.3. Raman displacements and infrared absorption wave numbers for 2,3-dibromo-2,3-dimethylbutane and 2,2,3,3-tetramethylbutane (hexamethylethane) are reported, together with depolarization factors for the Raman lines and relative intensities for both the Raman lines and the infrared absorption bands. The spectra were obtained in both benzene and CCl₄ solutions and the infrared measurements covered the region 400-5000 cm^-1. The results indicate that both mols. possess a center of symmetry and that the structure is the same in the two solvents. The dipole moment of 1.01 D. obtained by Mizushima, Morino, and Miyagawa (private communication) for 2,3-dibromo-2,3-dimethylbutane in CCl₄ solution can be explained by oscillations of 48° amplitude about the equilibrium trans position. Cf. C.A. 38, 3908.7.

Journal of Chemical Physics published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Product Details of C6H12Br2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Wu, Jicheng published the artcilePhotoredox-Catalyzed Cross-Coupling of Enamides for the Assembly of β-Difluoroimine Synthons, Category: bromides-buliding-blocks, the publication is Organic Letters (2017), 19(20), 5653-5656, database is CAplus and MEDLINE.

A photoredox-catalyzed formal C_sp3-C_sp3 cross-coupling reaction of enamides with bromodifluoro compounds is established. The resulting gem-difluoromethylenated γ-imines indicated high stability, excellent E/Z control, and broad functional group tolerance. These synthetic intermediates can efficiently transfer to difluoromethylenated γ-amino acids or δ-amino alcs. Mechanistic anal. indicates that a radical/SET mechanism proceeding via a difluoroalkyl radical may be involved in the catalytic cycle.

Organic Letters published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C6H8O3, Category: bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Carrera, Elisa I. published the artcileA Mechanistic Study of Halogen Addition and Photoelimination from π-Conjugated Tellurophenes, Application In Synthesis of 594-81-0, the publication is Journal of the American Chemical Society (2016), 138(8), 2678-2689, database is CAplus and MEDLINE.

The ability to drive reactivity using visible light is of importance for many disciplines of chem. and has significant implications for sustainable chem. Identifying photochem. active compounds and understanding photochem. mechanisms is important for the development of useful materials for synthesis and catalysis. Here we report a series of photoactive diphenyltellurophene compounds bearing electron-withdrawing and electron-donating substituents synthesized by alkyne coupling/ring closing or palladium-catalyzed ipso-arylation chem. The redox chem. of these compounds was studied with respect to oxidative addition and photoelimination of bromine, which is of importance for energy storage reactions involving X₂. The oxidative addition reaction mechanism was studied using d. functional theory, the results of which support a three-step mechanism involving the formation of an initial η¹ association complex, a monobrominated intermediate, and finally the dibrominated product. All of the tellurophene derivatives undergo photoreduction using 430, 447, or 617 nm light depending on the absorption properties of the compound Compounds bearing electron-withdrawing substituents have the highest photochem. quantum efficiencies in the presence of an alkene trap, with efficiencies of up to 42.4% for a pentafluorophenyl-functionalized tellurophene. The photoelimination reaction was studied in detail through bromine trapping experiments and laser flash photolysis, and a mechanism is proposed. The photoreaction, which occurs by release of bromine radicals, is competitive with intersystem crossing to the triplet state of the brominated species, as evidenced by the formation of singlet oxygen. These findings should be useful for the design of new photochem. active compounds supported by main-group elements.

Journal of the American Chemical Society published new progress about 594-81-0. 594-81-0 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 2,3-Dibromo-2,3-dimethylbutane, and the molecular formula is C6H12Br2, Application In Synthesis of 594-81-0.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary