Category: bromides-buliding-blocks

Ford, E. J. H. published the artcileCellular damage and changes in biliary excretion in a liver lesion of cattle, HPLC of Formula: 518-67-2, the publication is Journal of Pathology and Bacteriology (1962), 39-48, database is CAplus and MEDLINE.

Liver lesions, produced in adult cattle only, by parenteral administration of dimidium bromide can be used to assess a number of tests of hepatic dysfunction. Symptoms of early histol. changes, as detected by liver biopsies, first appeared 30-40 days after injection, and were reflected by marked increases in the serum levels of glutamic-oxalacetic transaminase, lactic dehydrogenase, isocitric dehydrogenase, and glutamic dehydrogenase. The level of glutamic-pyruvic transaminase was unchanged. Significant changes in serum enzyme levels occur even when histol. demonstrable damage is slight. These serum enzyme levels are sensitive indicators of early and mild hepatocellular damage. The later stages of hepatic lesion (40-50 days after injection) are accompanied by a fall in the rate of Bromsulphalein excretion. The phylloerythrin retention which was observed is likely to have been the underlying cause of the photosensitization observed in the original dimidium intoxication in Africa.

Journal of Pathology and Bacteriology published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, HPLC of Formula: 518-67-2.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Antoniak, Damian published the artcileAlkylation of Nitropyridines via Vicarious Nucleophilic Substitution, SDS of cas: 111-83-1, the publication is Organic Letters (2022), 24(2), 516-519, database is CAplus and MEDLINE.

Electrophilic nitropyridines reacted with sulfonyl-stabilized carbanions gave alkylated nitropyridins I [R = H, Me, n-octyl, etc.; R¹ = Me, Et, n-octyl, etc.; R² = H, OMe, SPh, etc.] products of C-H alkylation via vicarious nucleophilic substitution was reported. The process consisted of formation of the Meisenheimer-type adduct, followed by base-induced β-elimination of the sulfinic acid (e.g., PhSO₂H).

Organic Letters published new progress about 111-83-1. 111-83-1 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic hydrocarbon chain, name is 1-Bromooctane, and the molecular formula is C8H17Br, SDS of cas: 111-83-1.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Recsei, Carl published the artcileSynthesis of bis(aryloxy)fluoromethanes using a heterodihalocarbene strategy, Computed Properties of 401-55-8, the publication is Beilstein Journal of Organic Chemistry (2021), 813-818, database is CAplus and MEDLINE.

A simple and new procedure was developed for the construction of a bis(aryloxy)fluoromethane moiety I and ROCH(F)OR [R = 4-O₂NC₆H₄, 2,5-di-ClC₆H₄], for which no existing method was available.

Beilstein Journal of Organic Chemistry published new progress about 401-55-8. 401-55-8 belongs to bromides-buliding-blocks, auxiliary class Fluoride,Bromide,Aliphatic hydrocarbon chain,Ester, name is Ethylbromofluoroacetate, and the molecular formula is C4H6BrFO2, Computed Properties of 401-55-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Kratzer, Domenic published the artcileSynthetic Route to Sulfobetaine Methacrylates with Varying Charge Distance, Safety of Sodium 3-bromopropane-1-sulfonate, the publication is European Journal of Organic Chemistry (2014), 2014(36), 8064-8071, database is CAplus.

A general synthetic strategy is described that enables access to a library of new sulfobetaine methacrylates starting from com. available precursors. The three-step procedure allows the distance between the quaternary amine and the sulfonate group (inner charge distance) to be varied by selecting the corresponding dibromoalkane in the first step. A key step is the final esterification, in which methacrylic acid acts as solvent as well as reagent for the zwitterionic hydroxy intermediates. Thus, it is possible to synthesize monomeric precursors with up to twelve methylene groups between the pos. and the neg. charge. A selection of these monomers has been successfully tested for their ability to polymerize using free-radical polymerization

European Journal of Organic Chemistry published new progress about 55788-44-8. 55788-44-8 belongs to bromides-buliding-blocks, auxiliary class Bromide,Salt,Aliphatic hydrocarbon chain,Aliphatic hydrocarbon chain, name is Sodium 3-bromopropane-1-sulfonate, and the molecular formula is C3H6BrNaO3S, Safety of Sodium 3-bromopropane-1-sulfonate.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Heuser, Stefan published the artcileSynthesis of novel cyclopropylic sulfones and sulfonamides acting as glucokinase activators, HPLC of Formula: 18928-94-4, the publication is Tetrahedron Letters (2006), 47(16), 2675-2678, database is CAplus.

A synthetic route towards cyclopropylic compounds, which act as glucokinase activators is described herein. The present synthesis gives easy and rapid access to a wide variety of either sulfones or sulfonamides starting from readily available late-stage intermediates.

Tetrahedron Letters published new progress about 18928-94-4. 18928-94-4 belongs to bromides-buliding-blocks, auxiliary class Bromide,Aliphatic cyclic hydrocarbon, name is (2-Bromoethyl)cyclopentane, and the molecular formula is C7H13Br, HPLC of Formula: 18928-94-4.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Dymock, Brian W. published the artcileNovel, Potent Small-Molecule Inhibitors of the Molecular Chaperone Hsp90 Discovered through Structure-Based Design, Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, the publication is Journal of Medicinal Chemistry (2005), 48(13), 4212-4215, database is CAplus and MEDLINE.

The crystal structure of a previously reported screening hit 1 (CCT018159) bound to the N terminal domain of mol. chaperone Hsp90 has been used to design 5-amide analogs. These exhibit enhanced potency against the target in binding and functional assays with accompanying appropriate cellular pharmacodynamic changes. Compound 11 (VER-49009) compares favorably with the clin. evaluated 17-AAG.

Journal of Medicinal Chemistry published new progress about 111865-47-5. 111865-47-5 belongs to bromides-buliding-blocks, auxiliary class Benzenes, name is Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide, and the molecular formula is C10H16Br3N, Safety of Mono(N,N,N-trimethyl-1-phenylmethanaminium) tribromide.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Balthazar, Zsolt published the artcileTwo-phase titration of anionic surfactants, I. Study of the transition point of the titration carried out according to ISO 2271, Formula: C20H18BrN3, the publication is Magyar Kemiai Folyoirat (1977), 83(7), 294-7, database is CAplus.

Some properties of the Disulphine Blue [64366-33-2]-dimidium bromide [518-67-2] indicator system, prescribed by the international standard, were examined by UV-visible spectrometry. The dyes appeared in the CHCl3 phase only in the presence of an oppositely charged surfactant. In the modeling of practical end-points, the absorbance of the CHCl3 phase was markedly influenced by the presence of an anionic or cationic surfactant. The titration end-point determined photometrically using the 2 indicators was identical within exptl. error.

Magyar Kemiai Folyoirat published new progress about 518-67-2. 518-67-2 belongs to bromides-buliding-blocks, auxiliary class Other Aromatic Heterocyclic,Salt,Amine,Benzene, name is Dimidium bromide, and the molecular formula is C20H18BrN3, Formula: C20H18BrN3.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Sosnowska, Anita published the artcilePredicting enthalpy of vaporization for Persistent Organic Pollutants with Quantitative Structure-Property Relationship (QSPR) incorporating the influence of temperature on volatility, Application of 1,3-Dibromonaphthalene, the publication is Atmospheric Environment (2014), 10-18, database is CAplus.

Enthalpy of vaporization (ΔH_vap) is a thermodn. property associated with the dispersal of Persistent Organic Pollutants (POPs) in the environment. Common problem in the environmental risk assessment studies is the lack of exptl. measured ΔH_vap data. This problem can be solved by employing computational techniques, including QSPR (Quant. Structure-Property Relationship) modeling to predict properties of interest. Majority of the published QSPR models can be applied to predict the enthalpy of vaporization of compounds from only one, particular group of POPs (i.e., polychlorinated biphenyls, PCBs). We have developed a more general QSPR model to estimate the ΔH_vap values for 1436 polychlorinated and polybrominated benzenes, biphenyls, dibenzo-p-dioxins, dibenzofurans, di-Ph ethers, and naphthalenes. The QSPR model developed with Multiple Linear Regression anal. was characterized by satisfactory goodness-of-fit, robustness and the external predictive performance (R² = 0.888, Q²_CV = 0.878, Q²_Ext = 0.842, RMSE_C = 5.11, RMSE_CV = 5.34, RMSE_P = 5.74). Moreover, we quantified the temperature dependencies of vapor pressure for twelve groups of POPs based on the predictions at six different temperatures (logP_L(T)). In addition, we found a simple arithmetic relationship between the logarithmic values of vapor pressure in pairs of chloro- and bromo-analogs. By employing this relationship it is possible to estimate logP_L(T) for any brominated POP at any temperature utilizing only the logP_L(T) value for its chlorinated analogs.

Atmospheric Environment published new progress about 52358-73-3. 52358-73-3 belongs to bromides-buliding-blocks, auxiliary class Bromide,Naphthalene, name is 1,3-Dibromonaphthalene, and the molecular formula is C7H5ClN2S, Application of 1,3-Dibromonaphthalene.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Gujadhur, Rattan K. published the artcileFormation of Aryl-Nitrogen, Aryl-Oxygen, and Aryl-Carbon Bonds Using Well-Defined Copper(I)-Based Catalysts, Computed Properties of 25753-84-8, the publication is Organic Letters (2001), 3(26), 4315-4317, database is CAplus and MEDLINE.

The authors report mild synthetic protocols for the formation of aryl-carbon, aryl-nitrogen, and aryl-oxygen bonds based on soluble, well-defined copper(I) catalysts. These protocols do not require the use of palladium and/or expensive ligands. E.g., Cu(Phen)(PPh₃)Br catalyzed the coupling of PhCCH with PhI to give 80% PhCCPh.

Organic Letters published new progress about 25753-84-8. 25753-84-8 belongs to bromides-buliding-blocks, auxiliary class Copper, name is Bromo(1,10-phenanthroline)(triphenylphosphine)copper(I), and the molecular formula is C30H24BrCuN2P, Computed Properties of 25753-84-8.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary

Mondal, Rajib published the artcileThiophene-rich fused-aromatic thienopyrazine acceptor for donor-acceptor low band-gap polymers for OTFT and polymer solar cell applications, Related Products of bromides-buliding-blocks, the publication is Journal of Materials Chemistry (2010), 20(28), 5823-5834, database is CAplus.

Thiophene enriched fused-aromatic thieno[3,4-b]pyrazine systems were designed and employed to produce low band gap polymers (E_g = 1.0-1.4 eV) when copolymerized with fluorene and cyclopentadithiophene. The copolymers are mainly investigated for organic thin film transistor and organic photovoltaic applications. Mol. packing in the thin films of these polymers was investigated using Grazing incidence X-ray Scattering. Although both fluorene and cyclopentadithiophene polymers follow similar face to face π-π stacking, the latter polymers show much smaller lamellar d-spacings due to side-chain interdigitation between the lamellae. This lead to the higher charge carrier mobilities in cyclopentadithiophene polymers (up to 0.044 cm2/V.s) compared to fluorene polymers (up to 8.1 × 10^-3 cm²/V.s). Power conversion efficiency of 1.4% was achieved using fluorene copolymer in solar cells with a fullerene derivative as an acceptor. Although the cyclopentadithiophene polymers show lower band gaps with higher absorption coefficients compared to fluorene copolymers, but the power conversion efficiencies in solar cells of these polymers are low due to their low ionization potentials.

Journal of Materials Chemistry published new progress about 52431-30-8. 52431-30-8 belongs to bromides-buliding-blocks, auxiliary class Liquid Crystal &OLED Materials, name is 2,5-Dibromo-3,4-dinitrothiophene, and the molecular formula is C4Br2N2O4S, Related Products of bromides-buliding-blocks.

Referemce:
https://en.wikipedia.org/wiki/Bromide,
bromide – Wiktionary