Category: bromides-buliding-blocks

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 19111-87-6, formula is C18H11Br, Name is 2-Bromotriphenylene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Application In Synthesis of 19111-87-6.

Steiner, Ann-Kristin;Feofanov, Mikhail;Amsharov, Konstantin research published 《 Intramolecular aryl-aryl coupling via C-F bond activation tolerant towards C-I functionality》, the research content is summarized as follows. A transition-metal free activation of a particularly stable aromatic carbon-fluorine bond allowing intramol. aryl-aryl coupling which is orthogonal to carbon-iodine functionality was reported.

19111-87-6, 2-Bromotriphenylene is a useful research compound. Its molecular formula is C18H11Br and its molecular weight is 307.2 g/mol. The purity is usually 95%.
2-Bromotriphenylene is a brominating agent that has the ability to react with sodium carbonate and emit light. The luminescence of 2-bromotriphenylene can be used as an indicator of the degree of dilution, or how much water is present in a solution. It also emits light when it reacts with chloride ions in a reaction solution. 2-Bromotriphenylene can be used as a polymer matrix to form polymeric films, which are then used as catalysts for organic reactions. The luminescence properties of 2-bromotriphenylene make it suitable for use in functional theory experiments. This chemical compound is relatively low cost, and has been shown to have high yield in catalysis., Application In Synthesis of 19111-87-6

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 244205-40-1, formula is C6H6BBrO2, Name is (2-Bromophenyl)boronic acid, Computed Properties of 244205-40-1

Steiner, Ann-Kristin;Sharapa, Dmitry I.;Troyanov, Sergey I.;Nuss, Juergen;Amsharov, Konstantin research published 《 Carbon Origami via an Alumina-Assisted Cyclodehydrofluorination Strategy》, the research content is summarized as follows. The synthesis of pristine non-planar nanographenes (NGs) via a cyclodehydrofluorination strategy is reported and the creation of highly strained systems via alumina-assisted C-F bond activation is shown. Steric hindrance could execute an alternative coupling program leading to rare octagon formation offering access to elusive non-classical NGs. The combination of two alternative ways of folding could lead to the formation of various 3D NG objects, resembling the Japanese art of origami. The power of the presented “origami” approach is proved by the assembly of 12 challenging nanographenes that are π-isoelectronic to planar hexabenzocoronene but forced out of planarity.

244205-40-1, 2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.
2-Bromophenylboronic acid, also known as 2-Bromophenylboronic acid, is a useful research compound. Its molecular formula is C6H6BBrO2 and its molecular weight is 200.83 g/mol. The purity is usually 95%.
2-Bromophenylboronic acid is a glucose monitoring agent that has a ruthenium complex with an acidic environment. The nitro group and the amines are in close proximity to the boron center, and this proximity leads to a high nucleophilic character of the molecule. This reactivity allows 2-bromophenylboronic acid to be used as a fluorescence probe for acidic environments. 2-Bromophenylboronic acid also inhibits secretase enzymes, which are involved in Alzheimer’s disease and other neurodegenerative disorders. It is an inhibitor of γ-secretase, which is responsible for cleaving the amyloid precursor protein (APP), and it has shown efficacy against biphenyl, an anticancer drug that binds to benzodiazepine receptors. 2-Bromophenylboronic acid is also an enantiopure compound because all four substituents are different from each other., Computed Properties of 244205-40-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 4224-70-8, formula is C6H11BrO2, The most pervasive is the naturally produced bromomethane. COA of Formula: C6H11BrO2

Styles, Matthew J.;Early, Stephen A.;Tucholski, Trisha;West, Korbin H. J.;Ge, Ying;Blackwell, Helen E. research published 《 Chemical Control of Quorum Sensing in E. coli: Identification of Small Molecule Modulators of SdiA and Mechanistic Characterization of a Covalent Inhibitor》, the research content is summarized as follows. Enterohemorrhagic Escherichia coli (EHEC) is the causative agent of severe diarrheal disease in humans. Cattle are the natural reservoir of EHEC, and approx. 75% of EHEC infections in humans stem from bovine product s. Many common bacterial pathogens, including EHEC, rely on chem. communication systems, such as quorum sensing (QS), to regulate virulence and facilitate host colonization. EHEC uses SdiA from E. coli (SdiA_EC), an orphan LuxR-type receptor, to sense N-acyl L-homoserine lactone (AHL) QS signals produced by other members of the bovine enteric microbiome. SdiA_EC regulates two phenotypes critical for colonizing cattle: acid resistance and the formation of attaching and effacing lesions. Despite the importance of SdiA_EC, there is very little known about its selectivity for different AHL signals, and no chem. inhibitors that act specifically on SdiA_EC have been reported. Such compounds would represent valuable tools to study the roles of QS in EHEC virulence. To identify chem. modulators of SdiA_EC and delineate the structure-activity relationships (SARs) for AHL activity in this receptor, we report herein the screening of a focused library composed largely of AHLs and AHL analogs in an SdiA_EC reporter assay. We describe the identity and SARs of potent modulators of SdiA_EC activity, examine the promiscuity of SdiA_EC, characterize the mechanism of a covalent inhibitor, and provide phenotypic assay data to support that these compounds can control SdiA_EC-dependent acid resistance in E. coli. These SdiA_EC modulators could be used to advance the study of LuxR-type receptor/ligand interactions, the biol. roles of orphan LuxR-type receptors, and potential QS-based therapeutic approaches.

COA of Formula: C6H11BrO2, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 585-76-2, formula is C7H5BrO2, Name is 3-Bromobenzoic acid, Computed Properties of 585-76-2

Su, Junqi;Mo, Jia-Nan;Chen, Xiangyang;Umanzor, Alexander;Zhang, Zheng;Houk, Kendall N.;Zhao, Jiannan research published 《 Generation of oxyphosphonium ions by photoredox/cobaloxime catalysis for scalable amide and peptide synthesis in batch and continuous-flow》, the research content is summarized as follows. Phosphine-mediated deoxygenative nucleophilic substitutions, such as the Mitsunobu reaction, are of great importance in organic synthesis. However, the conventional protocols require stoichiometric oxidants to trigger the formation of the oxyphosphonium intermediates for the subsequent nucleophilic additions Through dual catalysis of photoredox and cobaloxime, we realized a radical strategy for the catalytic formation of acyloxyphosphonium ions that enables direct amidation. The deoxygenative protocol exhibits a broad scope and has been used in the late-stage amidation of drug mols. In addition to batch reactions, a continuous-flow reactor was developed, enabling rapid peptide synthesis on gram scale. The successful assembly of a tetrapeptide on the solid support further demonstrated the versatility of this photocatalytic system. Moreover, exptl. and computational studies are consistent with the hypothesis of acyloxyphosphonium ions being formed as the key intermediates.

Computed Properties of 585-76-2, 3-bromobenzoic acid is a bromobenzoic acid carrying a single bromo subsituent at the 3-position.
3-Bromobenzoic acid, also known as 3-Bromobenzoic acid, is a useful research compound. Its molecular formula is C7H5BrO2 and its molecular weight is 201.02 g/mol. The purity is usually 95%.
3-bromobenzoic acid is used as a reagent in the synthesis of deoxypodophyllotoxin derivatives with insecticidal activity. Also used as a reagent in the synthesis of thiazole derivatives with antibacterial activity.
3-bromobenzoic acid is a molecule that is classified as a Group P2. It has an electronegativity of 1.3 and an acidity of 0.8, which are both in the middle range of values for this group. 3-Bromobenzoic acid is soluble in water and is soluble in ethanol, acetone, and ether. The chemical structure of 3-bromobenzoic acid can be determined by its monoclonal antibody binding sites, electrochemical impedance spectroscopy data, and Langmuir adsorption isotherm data. 3-Bromobenzoic acid reacts with hydrochloric acid to form benzoate and HCl gas. Chronic exposure to 3-bromobenzoic acid has been shown to cause glutamate dehydrogenase inhibition, leading to an accumulation of p-hydroxybenzoic acid in the body. , 585-76-2.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Quality Control of 70-23-5.

Sigalapalli, Dilep Kumar;Kiranmai, Gaddam;Parimala Devi, G.;Tokala, Ramya;Sana, Sravani;Tripura, Chaturvedula;Jadhav, Govinda Shivaji;Kadagathur, Manasa;Shankaraiah, Nagula;Nagesh, Narayana;Babu, Bathini Nagendra;Tangellamudi, Neelima D. research published 《 Synthesis and biological evaluation of novel imidazo[1,2-a]pyridine-oxadiazole hybrids as anti-proliferative agents: study of microtubule polymerization inhibition and DNA binding》, the research content is summarized as follows. Towards the development of potential anticancer agents, a new series of imidazo[1,2-a]pyridine-oxadiazole hybrids I [R¹ = H, Me, R² = H; R¹ = Br, R² = Me; R³ = Ph, 4-Me₂NC₆H₄, 3,4,5-(MeO)₃C₆H₂, etc.] was synthesized and evaluated for their in vitro anticancer activity against lung cancer (A549) and prostate cancer (PC-3, DU-145) cell lines. Amongst the compounds tested, the compound I [R¹ = R² = H; R³ = 3,4,5-(MeO)₂C₆H₂; (II)] showed the highest potency on A549 cells with an IC₅₀ value of 2.8 ± 0.02μM. Flow cytometric anal. of A549 cells, treated with the compound II, showed apoptosis induction by annexin-v/PI dual staining assay and the effect of II on different phases of cell cycle was also analyzed. Target based studies demonstrated the inhibition of tubulin polymerization by the compound II at an IC₅₀ value of 3.45 ± 0.51μM and its effective binding with CT-DNA. Further, the mol. modeling studies revealed that II has a prominent binding affinity towards α/β-tubulin receptor with admirable physico-chem. properties.

Quality Control of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 5392-10-9, formula is C9H9BrO3, The most pervasive is the naturally produced bromomethane. Safety of 2-Bromo-4,5-dimethoxybenzaldehyde

Singh, Akansha;Kumar, Ravindra research published 《 Sustainable Passerini-tetrazole three component reaction (PT-3CR): selective synthesis of oxaborol-tetrazoles》, the research content is summarized as follows. A sustainable catalyst- and solvent-free Passerini-tetrazole three component reaction (PT-3CR) has been developed for the selective synthesis of benzoxaborol-tetrazoles for the first time. The synthetic potential of oxaboroles was demonstrated towards various functionalized tetrazoles, which are otherwise difficult to achieve through conventional PT-3CR from aromatic aldehydes/ketones. The reaction features high practicality, broad substrate scope and excellent yields (80-98%). Preliminary results of the asym. PT-3CR are also shown for the synthesis of chiral benzoxaboroles.

Safety of 2-Bromo-4,5-dimethoxybenzaldehyde, 2-Bromo-4,5-dimethoxybenzaldehyde is a useful research compound. Its molecular formula is C9H9BrO3 and its molecular weight is 245.07 g/mol. The purity is usually 95%.
2-Bromo-4,5-dimethoxybenzaldehyde is a synthetic compound that has been shown to be an effective agent for inducing apoptosis in leukemia cells. It is an efficient method for synthesizing the compound and ha2-Bromo-4,5-dimethoxybenzaldehyde induces cell death by topoisomerase-mediated DNA cleavage, which results in chromosomal fragmentation and high levels of reactive oxygen species in the cell., 5392-10-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Organic compounds having carbon bonded to bromine are called organic bromides. Application of C7H15Br.

Singh, Ankita;Malhotra, Shashwat;Bimal, Devla;Bouchet, Lydia M.;Wedepohl, Stefanie;Calderon, Marcelo;Prasad, Ashok K. research published 《 Synthesis, Self-Assembly, and Biological Activities of Pyrimidine-Based Cationic Amphiphiles》, the research content is summarized as follows. Pyrimidine-based cationic amphiphiles (PCAms), i.e., di-trifluoroacetic acid salts of N1-[1′-(1”,3”-diglycinatoxy-propane-2”-yl)-1′,2′,3′-triazole-4′-yl]methyl-N3-alkylpyrimidines have been synthesized utilizing naturally occurring biocompatible precursors, like glycerol, glycine, and uracil/ thymine in good yields. Synthesized PCAms consist of a hydrophilic head group comprising TFA salt of glyceryl 1,3-diglycinate and hydrophobic tail comprising of C-7 and C-12 N3-alkylated uracil or thymine conjugated via a 4-methylene-1,2,3-triazolyl linker. The physicochem. properties of all PCAms, such as critical aggregation concentration, hydrodynamic diameter, shape, and zeta potential (surface charge) were analyzed. These PCAms were also evaluated for their anti-proliferative and anti-tubercular activities. One of the synthesized PCAm exhibited 4- to 75-fold more activity than first-line anti-tubercular drugs streptomycin and isoniazid, resp., against the multidrug resistant clin. isolate 591 of Mycobacterium tuberculosis.

Application of C7H15Br, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 629-04-9, formula is C7H15Br, Name is 1-Bromoheptane. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Application In Synthesis of 629-04-9.

Singh, Dhandeep;Singh, Nirmal research published 《 Synthesis and Evaluation of 1-hydroxybenzotriazole Derivatives: Dual Inhibitors of Carbonic Anhydrase II and Sodium Hydrogen Exchanger I》, the research content is summarized as follows. Ischemia reperfusion injury is responsible for impaired graft functioning in organ transplants, cerebral dysfunction, ischemic heart diseases, systemic inflammatory response syndrome, gastrointestinal dysfunction, and multiple organ dysfunction syndromes. Intracellular pH is critical for cell survival in ischemia reperfusion injury. Sodium hydrogen exchanger I and carbonic anhydrase II are critical in the regulation of intracellular pH. Inhibition of sodium hydrogen exchanger I and carbonic anhydrase II during reperfusion is found to ameliorate ischemia reperfusion injury sep. An attempt is made to synthesize dual inhibitors of sodium hydrogen exchanger and carbonic anhydrase to have better potential drug mol. in ischemia reperfusion injury treatment. The hydroxybenzotriazole is considered as a central pharmacophore for this dual activity and 12 derivatives are synthesized. All derivatives are tested for sodium hydrogen exchanger I and carbonic anhydrase II inhibitory activity. The tosylate derivative is found to be the most potent derivative with IC₅₀ 158.7 +/= 8.4μM for carbonic anhydrase II and 31.07 +/= 1.06μM for sodium hydrogen exchanger I. Although the potency is less than standard drugs but this is the first report of dual inhibitor of carbonic anhydrase II and sodium hydrogen exchanger.

Application In Synthesis of 629-04-9, 1-Bromoheptane is a useful research compound. Its molecular formula is C7H15Br and its molecular weight is 179.1 g/mol. The purity is usually 95%.
1-Bromoheptane is a reagent that is used for the preparation of alkylthiophienylzinc chloride.
1-Bromoheptane is a reactive compound that is used in the preparation of p-hydroxybenzoic acid, which is an intermediate in the synthesis of many natural compounds. 1-Bromoheptane has been shown to have biological properties and to inhibit mitochondrial membrane potential. It also causes cell lysis and hepatic steatosis in mice. This compound has been shown to inhibit the activity of enzymes such as acetylcholinesterase, butyrylcholinesterase, and carboxylesterase. 1-Bromoheptane can be used as a model for studying the effects on congestive heart failure by increasing cardiac workloads or decreasing myocardial contractility., 629-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: 4-Bromobenzene-1,2-diamine.

Singh, Pooja S.;Badani, Purav M.;Kamble, Rajesh M. research published 《 Blue-orange emitting carbazole based donor-acceptor derivatives: Synthesis and studies of modulating acceptor unit on opto-electrochemical and theoretical properties》, the research content is summarized as follows. In order to demonstrate an effect of varying acceptor unit on optoelectronic properties of Donor-Acceptor (D-A) assembly, we herein designed and synthesized C-N coupled, carbazole based dyes 1-8 by employing Buchwald-Hartwig coupling amination reaction and fully characterized by spectroscopic methods. Presence of intramol. charge transfer (ICT) transitions (λ_max = 403-467 nm) in absorption spectra of all dyes reminiscent D-A assembly in it and emit in blue-yellow region (λ_emm = 467-565 nm) in solution state with marked pos. solvatochromism. The photophys. studies of some of the dyes in different THF/water mixtures revealed aggregation-induced emission (AIE) feature with the nanoparticles formation, as confirmed by dynamic light scattering (DLS) technique. The HOMO (-5.42 to -5.74 eV) and LUMO (-3.03 to -3.50 eV) energy level of these mols. measured by cyclic voltammetry suggest electron transporting property in it. Further, DFT/TDDFT calculation of dyes, indicate quite comparable theor. and exptl. photophys. and electrochem. data. Moreover, calculated singlet (S₁) and triplet (T₁) excitation energy levels by DFT/B3LYP/6-311 G+(d,p) shows small ΔE_ST value for some dyes and hence called as TADF emitters. Thus obtained all optoelectrochem. properties of dyes propose its potential use in optoelectronic devices and in biosensing.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Recommanded Product: 4-Bromobenzene-1,2-diamine

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 823-78-9, formula is C7H6Br2, Name is 1-Bromo-3-(bromomethyl)benzene. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Reference of 823-78-9.

Singh, Shikha;Trivedi, Laxmikant;Vasudev, Prema G.;Passarella, Daniele;Negi, Arvind S. research published 《 An efficient merging of DBU/enolate and DBU/benzyl bromide organocycles for the synthesis of alpha benzylated 1-indanone derivatives》, the research content is summarized as follows. The merging of dual organocycles of the bicyclic amidine base 1,8-diazabicyclo[5.4.0]undec-7-en (DBU) was demonstrated for the synthesis of alpha-benzylated 1-indanones. A highly reactive enolate intermediate was formed in the presence of DBU, which reacted with DBU/benzyl bromide salt to afford the product at 50°C temperature This simple and straight forward transformation using safer DBU reagent with easily available substrates and excellent yield provides a better alternative to the previously reported methods that required pyrophoric, costly reagents and high or very low-temperature reaction conditions.

823-78-9, 3-Bromobenzyl bromide undergoes reduction with diethylzinc in the presence of Pd(PPh3)4 to yield corresponding hydrocarbon.

3-Bromobenzyl bromide is a useful research compound. Its molecular formula is C7H6Br2 and its molecular weight is 249.93 g/mol. The purity is usually 95%.

3-Bromobenzyl bromide is a molecule that has been synthesized and shown to have anticancer activity. It inhibits the activity of cancer cells by binding to amines in these cells and preventing the formation of hydrogen bonds between these molecules. 3-Bromobenzyl bromide has also been shown to selectively inhibit the activity of NS5B polymerase, an enzyme that is important in the replication of the hepatitis C virus. The synthetic nature of this molecule makes it an attractive target for analytical methods such as nuclear magnetic resonance spectroscopy. This molecule also shows significant cytotoxicity against cancer cell lines in vitro, as well as inducing tumor necrosis factor-alpha (TNF-α) production in lps-stimulated murine macrophages., Reference of 823-78-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary