Tag: 100-200

Towards rigid-rod polyelectrolytes via well-defined precursor poly(p-phenylene)s substituted by 6-iodohexyl side chains was written by Rau, I. U.;Rehahn, M.. And the article was included in Acta Polymerica in 1994.Quality Control of 1-Bromo-6-methoxyhexane This article mentions the following:

A synthetic strategy is presented to prepare readily soluble poly-p-phenylene (PP) electrolytes of well-defined mol. constitution and conveniently determinable d.p. PP having 6-phenoxyhexyl pendant groups is treated with Me₃SiI to give 6-iodohexyl pendant groups; condensation with EtO₂C-p-C₆H₄ONa followed by hydrolysis gives the desired rigid-rod polyelectrolytes. Under appropriate reaction conditions all steps occur highly selectively and almost quant.; no degradation of the polymer backbone occurs as verified by high resolution NMR spectroscopy and osmometric investigations. Thus, structurally homogeneous carboxy-containing PP of well-known d.p. are prepared In the experiment, the researchers used many compounds, for example, 1-Bromo-6-methoxyhexane (cas: 50592-87-5Quality Control of 1-Bromo-6-methoxyhexane).

1-Bromo-6-methoxyhexane (cas: 50592-87-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Quality Control of 1-Bromo-6-methoxyhexane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of N-sulfenylimines from disulfides and primary methanamines was written by Kawecki, Robert. And the article was included in Journal of Organic Chemistry in 2022.Reference of 128-08-5 This article mentions the following:

N-sulfenylimines (sulfenimines, thiooximes, N-alkylidenesulfenamides) were efficiently synthesized through the reaction of primary amines and disulfides with NBS or bromine. This reaction can be carried out in an open flask at room temperature without the need for any transition metal-containing additives. The use of thiols instead of disulfides gave similar results. A wide range of amines were reacted with aryl and alkyldisulfides, resulting in the formation of sulfenimines in a yield of 44-99%. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Reference of 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Reference of 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chiral Chalcogenide-Catalyzed Enantioselective Electrophilic Hydrothiolation of Alkenes was written by Liang, Yaoyu;Jiao, Hui;Zhang, Hang;Wang, You-Qing;Zhao, Xiaodan. And the article was included in Organic Letters in 2022.Related Products of 128-08-5 This article mentions the following:

A new strategy for the construction of chiral sulfides by catalytic enantioselective hydrothiolation of alkenes via an electrophilic pathway has been developed. Using this strategy, cyclic and acyclic unactivated alkenes efficiently afforded various chiral products in the presence of electrophilic sulfur reagents and silanes through chiral chalcogenide catalysis. The obtained products were easily transformed into other types of valuable chiral sulfur-containing compounds Mechanistic studies revealed that the superior construction of chiral thiiranium ion intermediate is the key to achieving such a transformation. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Related Products of 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Related Products of 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of 2-bromo- and 2-phenyl-neo-confused porphyrins was written by Almejbel, Arwa S.;Lash, Timothy D.. And the article was included in Organic & Biomolecular Chemistry in 2020.Application of 881676-32-0 This article mentions the following:

Neo-confused porphyrins (neo-CPs), porphyrin isomers with a 1,3-connected pyrrolic subunit, are aromatic structures with a CNNN coordination core. Previously, examples of neo-CPs with fused benzo units or electron-withdrawing ester substituents have been described. In this paper, two new examples of neo-CPs are reported that lack a fused aromatic unit or an ester moiety, but instead have a bromo or Ph substituent on the neo-confused ring. Acid-catalyzed condensation of suitably substituted 1,2′-dipyrrylmethane dialdehydes with a 2,2′-dipyrrylmethane, followed by oxidation with aqueous ferric chloride solutions, afforded the neo-CPs in 40-45% yield. These porphyrin analogs had slightly reduced diatropic ring currents and slowly decomposed in solution The related palladium(II) and nickel(II) complexes proved to be very unstable, even though the diatropicity of the macrocycle was enhanced. This study shows that stabilizing substituents are necessary for investigations into this class of porphyrinoids. Attempts to prepare imidazole versions of neo-CPs were unsuccessful. In the experiment, the researchers used many compounds, for example, 5-Bromo-1H-pyrrole-3-carbaldehyde (cas: 881676-32-0Application of 881676-32-0).

5-Bromo-1H-pyrrole-3-carbaldehyde (cas: 881676-32-0) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 881676-32-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Simplified Synthetic Approach to Tetrabrominated Spiro-Cyclopentadithiophene and the Following Derivation to A-D-A Type Acceptor Molecules for Use in Polymer Solar Cells was written by Liu, Xiaochen;Zhang, Yuanxun;Wu, Jianchang;Ma, Yuchao;Lau, Kim K. T.;Fang, Jin;Ma, Chang-Qi;Lin, Yi. And the article was included in Journal of Organic Chemistry in 2022.Quality Control of 1-Bromopyrrolidine-2,5-dione This article mentions the following:

4,4â€?Spiro-bis[cyclopenta[2,1-b;3,4-b′]dithiophene] (SCT) is a versatile building block for constructing three-dimensional (3D) π-conjugated mols. for use in organic electronics. In this paper, we report a more convenient synthetic route to SCT and its derivatives, where a structurally sym. 3,3â€?dibromo-5,5â€?bis(trimethylsilyl)-2,2â€?bithiophene (2) serves as the precursor for both the synthesis of 4H-cyclopenta[2,1-b:3,4-b′]dithiophen-4-one (4) and 4-(5,5â€?bis(trimethylsilyl)-2,2â€?bithiophen-3-yl)-2,6-bis(trimethylsilyl)-4-hydroxy-cyclopenta[2,1-b;3,4-b′]dithiophene (5). The later one is the key intermediate for the final brominated SCT building block. Such a “two birds with one stone” strategy simplifies the synthetic approach to the SCT core. Functionalization on the SCT core with different terminal electron-deficient groups, including 1H-indene-1,3(2H)-dione (ID), 2-(3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile (IC), and 2-(5,6-difluoro-3-oxo-2,3-dihydro-1H-inden-1-ylidene)malononitrile (FIC), was carried out, yielding three spiro-conjugated A-D-A type mols., SCT-(TID)₄, SCT-(TIC)₄, SCT-(TFIC)₄, resp. The optical spectroscopy and electrochem. properties of these three compounds were investigated and compared to the corresponding linear oligomers. Results revealed that the IC and TFIC terminated compounds showed low-lying HOMO/LUMO energy levels with reduced optical bandgap, making them more suitable for use in polymer solar cells. A power conversion efficiency of 3.73% was achieved for the SCT-(TFIC)₄ based cell, demonstrating the application perspective of 3D mols. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Quality Control of 1-Bromopyrrolidine-2,5-dione).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Quality Control of 1-Bromopyrrolidine-2,5-dione

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The induction of chromosome aberrations in Vicia faba by halogenated butyl ethers was written by Michaelis, A.;Rieger, R.;Sieber, G.. And the article was included in Biologisches Zentralblatt in 1964.Electric Literature of C5H11BrO This article mentions the following:

Treatment with 10^-4 – 64 × 10^-4M Me 4-bromobutyl ether (I), 10^-4 – 60 × 10^-4M, Et 4-bromobutyl ether (II), 5 × 10^-5 – 10^-4 4,4′-dichlorodibutyl ether (III), and 5 × 10^-5 – 10^-4 4,4′ dibromodibutyl ether (IV) for 1-24 hrs. at pH 7, followed by 0.05% colchicine treatment provoked chromatid types of chromosome aberrations in V. faba roots, localized in the heterochromatic regions. The degree of mutagenic activity was IV > I > II > III. It is suggested that I-IV and N mustard have similar mechanism of mutagenic activity. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Electric Literature of C5H11BrO).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Electric Literature of C5H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

HF-Induced Intramolecular C-Arylation and C-Alkylation/Fluorination of 2-Aminoglycopyranoses was written by Probst, Nicolas;Martin, Amelie;Desire, Jerome;Mingot, Agnes;Marrot, Jerome;Bleriot, Yves;Thibaudeau, Sebastien. And the article was included in Organic Letters in 2017.Safety of 2-(Bromomethyl)-1,3-dimethylbenzene This article mentions the following:

Internal C-aryl and C-alkyl glycosides derived from 2-aminoglycopyranoses have been synthesized, exploiting a HF-mediated stereoselective intramol. glycosylation. These conditions are compatible with acetate protecting groups and allow introduction of aromatics with various electronic distributions at the anomeric position. This strategy also provides straightforward entry to original fluorinated sugar-azacycle hybrids via a tandem internal C-glycosylation/fluorination reaction starting from 2-N-allyl/propargyl glycopyranoses. All cyclizations proceed in a 1,2-cis stereocontrolled manner. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7Safety of 2-(Bromomethyl)-1,3-dimethylbenzene).

2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Safety of 2-(Bromomethyl)-1,3-dimethylbenzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of unsymmetrical dihydro triazine-2,4-diones by the N-N bond fragmentation of urazoles followed by intramolecular cyclization was written by Panga, Subhaskar R.;Hall, Roger G.;Samant, Rashmi V.;Montgomery, Mark;Shyadligeri, Ashok S.. And the article was included in Tetrahedron Letters in 2022.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione This article mentions the following:

A new synthesis of unsym. dihydro triazine-2,4-diones I (R¹ = Ph, 3-ClC₆H₄, 4-MeOC₆H₄, 1-phenyl-3-trifluoromethylpyrazol-5-yl, etc., R² = H, R³ = Me; R¹ = 4-ClC₆H₄, R² = H, Me, R³ = Me, Et, i-Pr) has been accomplished through the strategy of a base-induced fragmentation of urazole derivatives II followed by an intramol. cyclization. Treating substituted urazole derivativesII with LDA resulted in fragmentation of the N-N bond generating an imine, which was trapped in an intramol. fashion to give products I in good to excellent yields. Features of this transformation include atom economy and a broad tolerance of aryl substituents. Where differentially substituted urazole derivatives were employed, only one dihydrotriazine-2,4-dione isomer was obtained. The transformation of the formed dihydrotriazine-2,4-diones into triazine-2,4-diones and triazine-2,4,6-triones has been demonstrated, enlarging the scope of this approach. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Application In Synthesis of 1-Bromopyrrolidine-2,5-dione).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Polythiophenes with unusual electrical and optical properties based on donor acceptor alternance strategy was written by Gallazzi, Maria C.;Toscano, Francesca;Paganuzzi, Daniela;Bertarelli, Chiara;Farina, Alessandra;Zotti, Gianni. And the article was included in Macromolecular Chemistry and Physics in 2001.Safety of 5-Bromothiophene-3-carbaldehyde This article mentions the following:

The strategy of donor-acceptor alternation was adopted to reduce the energy gap in substituted polythiophenes; energy gaps down to 1.2 eV were obtained, which is a very low value in the class of polythiophenes. Alkoxy groups and dicyanoethenyl groups were used to prepare electron-rich and electron-poor thiophene units. The copolymers were obtained by coupling reaction methods (Suzuki) and by oxidative chem. and electrochem. polymerization of an opportunely designed substituted terthiophene. X-ray studies and spectroscopic data on the copolymers evidenced that the dicyanoethenyl group as substituent was rather steric demanding and susceptible of side reactions also preventing the n-doping of the material. The conductivity behavior was unusual but compatible with localized charge carriers. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Safety of 5-Bromothiophene-3-carbaldehyde).

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Safety of 5-Bromothiophene-3-carbaldehyde

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Podands with 10-ethyl-3,7-dithienyl-10H-phenothiazine core: synthesis and structural analysis was written by Petran, Anca;Bogdan, Elena;Terec, Anamaria;Grosu, Ion. And the article was included in Revue Roumaine de Chimie in 2012.Quality Control of 5-Bromothiophene-3-carbaldehyde This article mentions the following:

New podands showing substituted thiophene groups connected to positions 3 and 7 of a central 10-ethyl-10H-phenothiazine unit were obtained in good yield by cross-coupling reaction strategy. The thiophene rings are substituted either with formyl or hydroxymethyl groups, either at position 4′ or at position 5′. These podands can participate by various reactions to the enclosure of macrocyclic compounds and the reported compounds are versatile precursors for host mols. embedding thiophene and phenothiazine moieties. The structure of the podands was investigated by NMR and MS spectra. The title compounds thus formed included a dimethanol (I) and alc. regioisomer analog (II). The synthesis of the target compounds was achieved using 10-ethyl-3,7-bis(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-10H-phenothiazine, 3,7-dibromo-10-ethyl-10H-phenothiazine as starting materials. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Quality Control of 5-Bromothiophene-3-carbaldehyde).

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Quality Control of 5-Bromothiophene-3-carbaldehyde

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary