Tag: 100-200

Halide Perovskite Cluster Precursors: A Paradigm for Obtaining Structure- and Color-Tunable Light-Emitting Nanocrystals was written by Dutta, Sumit Kumar;Peng, Lucheng;Hudait, Biswajit;Xie, Renguo;Pradhan, Narayan. And the article was included in ACS Energy Letters in 2022.SDS of cas: 128-08-5 This article mentions the following:

The compositions of precursors during the syntheses of CsPbX₃ nanocrystals typically determine the resulting crystal phase and stability. Different precursors providing single or multiple constituent ions have already been developed for tuning the reaction pathways for architecting different sizes and shapes of such nanocrystals. Among these, the CsPbBr₃ clusters, composed of Cs, Pb, and Br, as well as limited ligands, employed as single-source precursors, provide an ideal pathway for obtaining a wide window of size/shape-tunable CsPbBr₃ nanocrystals. Recent reports also revealed that this pathway can lead to the epitaxial growth of non-perovskite nanostructures on perovskite nanocrystals. Further, the limited ligands here helped in shape modulation by opening different facets and also triggering facet directed connections of the nanocrystals. Keeping those in mind, the importance of these unique cluster precursors for the development of halide perovskite nanocrystals and their heterostructures is discussed, and possibilities for their utilization in different unexplored areas of research are proposed in this Perspective. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5SDS of cas: 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.SDS of cas: 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

S_N2 Substitution Reactions at the Amide Nitrogen in the Anomeric Mutagens, N-Acyloxy-N-alkoxyamides was written by Cavanagh, Katie L.;Glover, Stephen A.;Price, Helen L.;Schumacher, Rhiannon R.. And the article was included in Australian Journal of Chemistry in 2009.Application In Synthesis of 2-(Bromomethyl)-1,3-dimethylbenzene This article mentions the following:

N-Acyloxy-N-alkoxyamides 1a are unusual anomeric amides that are pyramidal at the nitrogen because of bis oxyl substitution. Through this configuration, they lose most of their amide character and resemble α-haloketones in reactivity. They are susceptible to S_N2 reactions at nitrogen, a process that is responsible for their mutagenic behavior. Kinetic studies have been carried out with the nucleophile N-methylaniline that show that, like S_N2 reactions at carbon centers, the rate constant for S_N2 displacement of carboxylate is lowered by branching β to the nitrogen center, or bulky groups on the alkoxyl side chain. Branching or bulky groups on the carboxylate leaving group, however, do not impact on the rate of substitution, which is mostly controlled by the pK_A of the departing carboxylate group. These results are in line with computed properties for the model reaction of ammonia with N-acetoxy-N-methoxyacetamide but are in contrast to the role of steric effects on their mutagenicity. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7Application In Synthesis of 2-(Bromomethyl)-1,3-dimethylbenzene).

2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application In Synthesis of 2-(Bromomethyl)-1,3-dimethylbenzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Sc(OTf)₃-Mediated [4 + 2] Annulations of N-Carbonyl Aryldiazenes with Cyclopentadiene to Construct Cinnoline Derivatives: Azo-Povarov Reaction was written by Jimenez-Aberasturi, Xabier;Palacios, Francisco;de los Santos, Jesus M.. And the article was included in Journal of Organic Chemistry in 2022.Name: 1-Bromopyrrolidine-2,5-dione This article mentions the following:

The first accomplishment of the azo-Povarov reaction involving Sc(OTf)₃-catalyzed [4 + 2] annulations of N-carbonyl aryldiazenes with cyclopentadiene in chloroform, in which N-carbonyl aryldiazenes act as 4π-electron donors. Hence, this protocol offer a rapid access to an array of cinnoline derivatives in moderate to good yields for substrates over a wide scope. The synthetic potential of the protocol was achieved by the gram-scale reaction and further derivatization of the obtained polycyclic product. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Name: 1-Bromopyrrolidine-2,5-dione).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Name: 1-Bromopyrrolidine-2,5-dione

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Catalytic, Directed C-C Bond Functionalization of Styrenes was written by Onodera, Shunsuke;Togashi, Ryo;Ishikawa, Soya;Kochi, Takuya;Kakiuchi, Fumitoshi. And the article was included in Journal of the American Chemical Society in 2020.Name: 3-Bromo-4-fluorotoluene This article mentions the following:

A method for catalytic conversion of C(aryl)-C(alkenyl) bonds in styrene derivatives R¹-2-R²C₆H₃C(=CHR₄)R³ (R¹ = H, 4-Me, 3-Cl, 5-Me, etc.; R² = 1-pyrazolyl, 2-pyridyl; R³ = H, Me, Ph, 4-methoxyphenyl, etc.; R₄ = H, Ph, 4-chlorophenyl) to new C-C bonds is developed. In the presence of a rhodium catalyst, the alkenyl groups of styrenes bearing a pyrazolyl directing group were efficiently converted to other carbon substituents upon reacting with various alkenes RCH=CH₂ (R = 4-methylhex-1-en-1-yl, 2-cyclohexylethenyl, 2-phenylethenyl, etc.) and allyl alcs. R⁵CH(OH)CH=CH₂(R⁵ = cyclohexyl, Me, Et, etc.). It is also indicated that the C-C bond cleavage proceeded via a hydrometalation/β-carbon elimination pathway. In the experiment, the researchers used many compounds, for example, 3-Bromo-4-fluorotoluene (cas: 452-62-0Name: 3-Bromo-4-fluorotoluene).

3-Bromo-4-fluorotoluene (cas: 452-62-0) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Name: 3-Bromo-4-fluorotoluene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

1,2-Bis(diphenylphosphino)ethane (dppe)/NBS: An Unprecedented Combination for Deoxygenation of Sulfoxides Under Mild Conditions was written by Joshi, Asha;Iqbal, Zafar;De, Saroj Ranjan. And the article was included in ChemistrySelect in 2022.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione This article mentions the following:

A novel, efficient and metal-free strategy for the deoxygenation of sulfoxides to sulfides was disclosed under mild conditions using dppe/NBS reagent system. Among several developed methods using phosphine based ligands, very few are convenient as most of them are confined to harsh reaction conditions, inseparable side products, moderate yields, and the use of costly and toxic reagents. The developed dppe/NBS promoted deoxygenation strategy tolerates a wide range of functional groups to afford good yields of desired sulfides. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Application In Synthesis of 1-Bromopyrrolidine-2,5-dione).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Phenazine syntheses. VII. Certain disubstituted phenazines was written by Vivian, Donald L.. And the article was included in Journal of Organic Chemistry in 1956.Name: 1-Bromo-4-methoxybutane This article mentions the following:

Disubstituted phenazines are prepared by ring closure of substituted 2-nitrodiphenylamines. Refluxing 25 g. 2,6-(O₂N)₂C₆H₃Cl, 24 g. p-MeOC₆H₄NH₂, 37.5 g. NaOAc.3H₂O, and 375 cc. 95% EtOH 16 hrs. yields 91% 2,6-dinitro-4′-methoxydiphenylamine, small yellowish red needles, m. 171-3°, which (1 g.), heated 20 min. at 250-62° with (CO₂)₂Fe.2H₂O (I) and 10 g. granulated Pb (II), gives 0.15 g. 7-methoxy-1-nitrophenazine, yellowish needles, m. 235-6°. Heating 76.5 g. N,N-dimethyl-p-phenylenediamine, 96 g. 2,5-(O₂N)₂C₆H₃Cl, and 90 g. anhydrous NaOAc 40 hrs. at 195-210°, steam distg, the mixture, adding 100 cc. HCl, steam distilling it again, and extracting the distillation residue with Et₂O give 60 g. 4-chloro-4′-dimethylamino-2-nitrodiphenylmine, brick-red microcrystals, m. 144-6°, which (1 g.), heated with 1.3 g. I and 10 g. II 10-15 min. at 250-60°, yields 0.4 g. 2-chloro-8-dimethylaminophenazine, brownish red needles, m. 194-5°. Refluxing 20 g. 4,5-dinitroveratrole, 24.5 g. PhNH₂, and 40 cc. absolute EtOH 3 weeks, steam distilling the mixture, and chromatographing the product on Al₂O₃ give 17.4 g. 4,5-dimethoxy-2-nitrodiphenylamine, orange needles, m. 120.5-1.5°, which (2 g.) heated 15 min. at 255-60° with 2.6 g. I and 20 g. II, yields 0.43 g. 2,3-dimethoxyphenazine, light yellow needles, m. 280-1°. Heating 28.1 g. 2,5-Br₂C₆H₃NO₂, 20.2 g. 5-bromo-2-anisidine, and 30 g. anhydrous NaOAc 40 hrs. at 200-10° yields 30.2 g. 4,5′-dibromo-2′-methoxy-2-nitrodiphenylamine, small red-orange needles, m. 198-200°, which (2 g.), heated 12 min. at 260° with 2.6 g. I and 20 g. II, yields 0.8 g. 2,7-dibromophenazine, bright yellow needles or prisms, m. 251-2°. Heating 200 g. 2,5-Cl₂C₆H₃NO₂, 200 g. o-MeC₆H₄NH₂, and 200 g. NaOAc 40 hrs. at 180° gives 20.5% 4-chloro-2′-methyl-2-nitrodiphenylamine, orange prisms, m. 103-5°, which (10 g.), heated with 12 g. I and 100 g. II 12 min. at 270°, yields 3.5 g. 7-chloro-1-methylphenazine, yellow needles, m. 28-9°. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Name: 1-Bromo-4-methoxybutane).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Name: 1-Bromo-4-methoxybutane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Transition Metal Free Stannylation of Alkyl Halides: The Rapid Synthesis of Alkyltrimethylstannanes was written by Li, Songyi;Lian, Chang;Yue, Guanglu;Zhang, Jianning;Qiu, Di;Mo, Fanyang. And the article was included in Journal of Organic Chemistry in 2022.Related Products of 4457-67-4 This article mentions the following:

A transition metal free stannylation reaction of alkyl bromides and iodides with hexamethyldistannane was developed. This protocol is operationally convenient and features a rapid reaction and good functional group tolerance. A wide range of functionalized primary and secondary alkyl and benzyl tri-Me stannanes were prepared in moderate to excellent yields. The success of the gram-scale procedure and tandem Stille coupling reaction has allowed this protocol to demonstrate potential for application in organic synthesis. Both exptl. and theor. studies reveal the mechanistic details of this stannylation reaction. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Related Products of 4457-67-4).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Related Products of 4457-67-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Structure-Activity Relationship Studies and Molecular Modeling of Naphthalene-Based Sphingosine Kinase 2 Inhibitors was written by Congdon, Molly D.;Kharel, Yugesh;Brown, Anne M.;Lewis, Stephanie N.;Bevan, David R.;Lynch, Kevin R.;Santos, Webster L.. And the article was included in ACS Medicinal Chemistry Letters in 2016.Name: 1-Bromo-4-methoxybutane This article mentions the following:

The two isoforms of sphingosine kinase (SphK1 and SphK2) are the only enzymes that phosphorylate sphingosine to sphingosine-1-phosphate (S1P), which is a pleiotropic lipid mediator involved in a broad range of cellular processes including migration, proliferation, and inflammation. SphKs are targets for various diseases such as cancer, fibrosis, and Alzheimer’s and sickle cell disease. Herein, the authors disclose the structure-activity profile of naphthalene-containing SphK inhibitors, e.g. I, and mol. modeling studies that reveal a key mol. switch that controls SphK selectivity. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Name: 1-Bromo-4-methoxybutane).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Name: 1-Bromo-4-methoxybutane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Constructing Soluble Anthracene-Based Blue Emitters Free of Electrically Inert Alkyl Chains for Efficient Evaporation- and Solution-Based OLEDs was written by Noda, Taito;Sasabe, Hisahiro;Owada, Tsukasa;Sugiyama, Ryo;Arai, Ayato;Kumada, Kengo;Tsuneyama, Hisaki;Saito, Yu;Kido, Junji. And the article was included in ChemPlusChem in 2022.Application of 128-08-5 This article mentions the following:

Anthracene derivatives are one of the most promising blue emitters employed in organic light-emitting devices (OLEDs) because of their electrochem. and thermal stabilities. However, their high crystallinity owing to their large π-planar structures severely impedes the progress in the development of solution-based systems. In this work, we developed two types of highly soluble multifunctional anthracene derivatives terminated with ortho-biphenyl and triphenylamine moieties and showed high solubility in general organic solvents such as toluene, THF, and cyclohexanone at high concentrations (>10 mg mL-1), and showed blue emission with a peak wavelength of âˆ?65 nm and a high photoluminescence quantum yield that ranges up to 81 %. Notably, these emitters are suitable for fabricating both evaporation- and solution-based systems. The evaporation-based system OLED achieved a high external quantum efficiency (EQE) of 5.4 %. While the solution-processed system realized 4.8 %, exhibiting the best performance among the anthracene-based solution-processed OLEDs so far. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Application of 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application of 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

2-Alkyloxyalkylthiohypoxanthines as new potent inhibitors of xanthine oxidase was written by Biagi, Giuliana;Giorgi, Irene;Pacchini, Federica;Livi, Oreste;Scartoni, Valerio. And the article was included in Farmaco in 2001.Reference of 4457-67-4 This article mentions the following:

The title compounds were prepared and tested as xanthine oxidase (XO) inhibitors. Results evidenced that potency was related to the position of the oxygen atom in the 2-linear chain and that it grew with distance from the sulfur atom until it became equipotent to 2-n-hexylthiohypoxanthine. Enzymic oxidation on C(2) occurred in the 8-alkylthiohypoxanthines. On the contrary, oxidation on C(8) did not occur in the 2-alkythioderivatives, demonstrating that the chain forced these mols. to form a complex with molybdenum(VI) involving only the N(3) and N(9) nitrogen atoms. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Reference of 4457-67-4).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Reference of 4457-67-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary