Tag: 100-200

Amino acid-promoted C-H alkylation with alkylboronic acids using a removable directing group was written by Zhang, Yu;Jiang, Hang;Chen, Dushen;Zhang, Yanghui. And the article was included in Organic & Biomolecular Chemistry in 2016.Category: bromides-buliding-blocks This article mentions the following:

Palladium-catalyzed C-H alkylation reaction with alkylboronic acids has successfully been developed using a removable pyridyldiisopropylsilyl directing group. The amino acid played a crucial role as a ligand in the reaction. The alkylation protocol is also applicable to the coupling of C(sp³)-H bonds with alkylboronic acids. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Category: bromides-buliding-blocks).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

cis-Annulation of an oxazoline fragment to levoglucosenone and the synthesis of 4-substituted 3-amino-1,6-anhydro-3-deoxy-β-D-mannopyranose was written by Sharipov, Bulat T.;Davidova, Anna N.;Valeev, Farid A.. And the article was included in Chemistry of Heterocyclic Compounds (New York, NY, United States) in 2022.Related Products of 128-08-5 This article mentions the following:

Chiral 2-trichloromethyl-oxazolines 4,5-cis-annulated to a carbohydrate fragment were synthesized on the basis of levoglucosenone. The synthesized compounds were converted by acid hydrolysis into 4-substituted 3-amino-1,6-anhydro-3-deoxy-β-D-mannopyranoses. Intramol. amination of allyl trichloroacetimidates by electrophilic reagents was used to construct the oxazoline ring. It was established that trichloroacetimidates containing an epoxide ring in α,β-positions spontaneously undergo re-cyclization with the formation of an oxazoline ring. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Related Products of 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Related Products of 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Novel intramolecular π-π-interaction in a BODIPY system by oxidation of a single selenium center: geometrical stamping and spectroscopic and spectrometric distinctions was written by Kim, Youngsam;Jun, Taehong;Mulay, Sandip V.;Manjare, Sudesh T.;Kwak, Jinseong;Lee, Yunho;Churchill, David G.. And the article was included in Dalton Transactions in 2017.Computed Properties of C5H3BrOS This article mentions the following:

A new BODIPY system displaying an intramol. π-π-interaction was synthesized and studied. When the selenium center was oxidized, the substituted Ph group undergoes π-π stacking with one side of the BODIPY core. The oxidized form showed, not only a down-field shift in the NMR peak, but also splitting due to geometrical changes that arise when going from C_s to C₁. The compound was characterized by X-ray diffraction; DFT methods helped elucidate the influence of the unexpected π-π stack and its connection to the photophys. properties imparted by the Se oxidation In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Computed Properties of C5H3BrOS).

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Computed Properties of C5H3BrOS

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Polar tagging in the synthesis of monodisperse oligo(p-phenyleneethynylene)s and an update on the synthesis of oligoPPEs was written by Sahoo, Dhananjaya;Thiele, Susanne;Schulte, Miriam;Ramezanian, Navid;Godt, Adelheid. And the article was included in Beilstein Journal of Organic Chemistry in 2010.Related Products of 50592-87-5 This article mentions the following:

One important access to monodisperse (functionalized) oligoPPEs is based on the orthogonality of the alkyne protecting groups triisopropylsilyl and hydroxymethyl (HOM) and on the polar tagging with the hydroxymethyl moiety for an easy chromatog. separation of the products. This paper provides an update of this synthetic route. For the deprotection of HOM protected alkynes, γ-MnO₂ proved to be better than (highly) activated MnO₂. The use of HOM as an alkyne protecting group is accompanied by carbometalation as a side reaction in the alkynyl-aryl coupling. The extent of carbometalation can be distinctly reduced through substitution of HOM for 1-hydroxyethyl. The strategy of polar tagging is extended by embedding ether linkages 2 within the solubilizing side chains. With building blocks such as 1,4-diiodo-2,5-bis(6-methoxyhexyl) less steps are needed to assemble oligoPPEs with functional end groups and the isolation of pure compounds becomes simple. For the preparation of 1,4-dialkyl-2,5-diiodobenzene a better procedure is presented together with the finding that 1,4-dialkyl-2,3-diiodobenzene, a constitutional isomer of 1,4-dialkyl-2,5-diiodobenzene, is one of the byproducts. In the experiment, the researchers used many compounds, for example, 1-Bromo-6-methoxyhexane (cas: 50592-87-5Related Products of 50592-87-5).

1-Bromo-6-methoxyhexane (cas: 50592-87-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Related Products of 50592-87-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Polarographic behavior of disubstituted derivatives of benzene or heterocycles. I. Substituted bromothiophenes was written by Person, Maurice;Mora, Raymond. And the article was included in Bulletin de la Societe Chimique de France in 1973.Category: bromides-buliding-blocks This article mentions the following:

The polarog. of the title compounds was studied at pH 2-15 in aqueous and anhydrous EtOH. In the group of 3- and 5-bromo-2-formyl-, 2-bromo-3-formyl-, and 3-bromo-2-acetylthiophenes, the wave for the splitting of the C-Br bond precedes that for the carbonyl group. Their oximes and thiosemicarbazones behave similarly. In the group of 4-bromo-2-formyl-, 2- and 5-bromo-3-formylthiophenes, the corresponding wave positions were reversed from the 1st group. The 5-bromothiophenes, substituted in the 2-position by CO2H, CO2Me, and CONH2, give C-Br scission waves which are identical in ethanolic and aqueous solutions depending on the pH. The effects of structure and the influence of substituents on the lability of the C-Br bond is discussed. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Category: bromides-buliding-blocks).

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Molecular Engineering of Robust Starburst-Based Organic Photosensitizers for Highly Efficient Photocatalytic Hydrogen Generation from Water was written by Kwok, Yan-Yi;Ho, Po-Yu;Wei, Ying;Zheng, Zhong;Yiu, Sze-Chun;Ho, Cheuk-Lam;Huang, Shuping. And the article was included in Chemistry of Materials in 2022.Formula: C4H4BrNO2 This article mentions the following:

Six donor-donor-π-acceptor (D-D-π-A) triphenylamine-based starburst organic dyes with different electron-donating moieties and thiophene-based π-linkers were synthesized and characterized. Their photophys. and electrochem. properties, together with their photocatalytic hydrogen evolution performance as photosensitizers (PSs), were investigated. Distinctive and prolonged hydrogen evolution performances of these PSs under visible-light irradiation from water in their platinized TiO₂ composites were demonstrated: a turnover number (TON) of up to 24 900 (252 h) with 1560 μmol (37.6 mL) hydrogen produced, an initial turnover frequency (TOF_i) of 1130 h^-1, initial activity (Activity_i) of 705 mmol g^-1 h^-1, and initial apparent quantum yield (AQY_i) of 12.1%. To the best of our knowledge, according to the TOF and TON values, the designed PS system is one of the most efficient and robust photocatalytic H₂ generation systems adopting a TiO₂-anchoring mol. PS in the literature. The results showed that the starburst triarylamine donor moiety with phenothiazine functionality and the alkyl chain on the thiophene π-linker could boost the performance and longevity of the photocatalytic system, providing a powerful strategy for the development of starburst-based highly efficient and robust D-D-π-A organic photosensitizers in the future. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Formula: C4H4BrNO2).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Formula: C4H4BrNO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Effect of structural factors and solvent nature in bromination of anilines was written by Bagmanov, B. T.. And the article was included in Russian Journal of Applied Chemistry in 2009.Category: bromides-buliding-blocks This article mentions the following:

Electrophilic bromination of anilines containing various ortho-, meta-, and para-substituents in the aromatic ring was studied. The optimal conditions for the synthesis of mono-, di-, tri-, and tetrabrominated anilines and brominated analog of Aniline Black were found. In the experiment, the researchers used many compounds, for example, 4-Amino-3-bromophenol (cas: 74440-80-5Category: bromides-buliding-blocks).

4-Amino-3-bromophenol (cas: 74440-80-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A benzodithiophene-based semiconducting polymer for organic thin film transistor was written by Hong, Jung-A.;Kim, Ran;Yun, Hui-Jun;Park, Joung-Man;Shin, Sung Chul;Kim, Yun-Hi. And the article was included in Bulletin of the Korean Chemical Society in 2013.Recommanded Product: 18791-79-2 This article mentions the following:

Benzodithiophene based organic semiconducting polymer was designed and synthesized by stille coupling reaction. The structure of polymer was confirmed by NMR and IR. The weight average mol. weight (M_w) of polymer was 8,400 using GPC with polydispersity index of 1.4. The thermal, optical and electrochem. properties of polymer were characterized by TGA and DSC, UV-vis absorption and cyclic voltammetry. OTFT device using PBDT-10 exhibited the mobility of 7.2 × 10^-5 cm² V^-1 s^-1 and I_on/I_off of 2.41 × 10³. The film morphol. and crystallinity of PBDT-10, was studied using AFM and x-ray diffraction. In the experiment, the researchers used many compounds, for example, 5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2Recommanded Product: 18791-79-2).

5-Bromothiophene-3-carbaldehyde (cas: 18791-79-2) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Recommanded Product: 18791-79-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

No-Carrier-Added (4-Fluoro-3-[¹³¹I]iodobenzyl)guanidine and (3-[²¹¹At]Astato-4-fluorobenzyl)guanidine was written by Vaidyanathan, Ganesan;Affleck, Donna J.;Zalutsky, Michael R.. And the article was included in Bioconjugate Chemistry in 1996.SDS of cas: 452-62-0 This article mentions the following:

With 3-bromo-4-fluorotoluene as starting material, [4-fluoro-3-(trimethylsilyl)benzyl]guanidine was prepared in five steps in 1.5% overall yield. Radioiodination of this silicon precursor using N-chlorosuccinimide in trifluoroacetic acid at room temperature for 5 min gave (4-fluoro-3-[¹³¹I]iodobenzyl)guanidine ([¹³¹I]FIBG) in 50-60% radiochem. yield. A byproduct which had a retention time in two HPLC systems similar to that of (m-iodobenzyl)guanidine (MIBG) was formed in about 30% yield. [¹³¹I]FIBG was stable up to 3 h under these conditions of iodination, indicating that the byproduct is not generated as a result of [¹³¹I]FIBG degradation Using hydrogen peroxide as the oxidant in aqueous medium and a reaction time of 30 min at 50 °C, yields of [¹³¹I]FIBG could be increased to 75-80%, with less than 7% of the byproduct formed under these conditions. Astatination of the silicon precursor using N-chlorosuccinimide in trifluoroacetic acid at 70 °C gave 65-70% radiochem. yield of (3-[²¹¹At]astato-4-fluorobenzyl)guanidine ([²¹¹At]AFBG) in 10-15 min; about 17% of the byproduct formation was seen. Astatination of the silicon precursor under aqueous conditions using hydrogen peroxide was not successful. In the experiment, the researchers used many compounds, for example, 3-Bromo-4-fluorotoluene (cas: 452-62-0SDS of cas: 452-62-0).

3-Bromo-4-fluorotoluene (cas: 452-62-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.SDS of cas: 452-62-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Nickel-Catalyzed Asymmetric Reductive Arylalkylation of Unactivated Alkenes was written by Jin, Youxiang;Wang, Chuan. And the article was included in Angewandte Chemie, International Edition in 2019.Reference of 4457-67-4 This article mentions the following:

Reported is an asym. reductive dicarbofunctionalization of unactivated alkenes [e.g., 1-bromo-2-(3-methylbut-3-en-1-yl)benzene + 4-bromobutyl acetate �I (69%, 94% ee)]. Under the catalysis of a Ni/BOX system, various aryl bromides, incorporating a pendant olefinic unit, were successfully reacted with an array of primary alkyl bromides in the presence of Zn as a reductant, furnishing a series of benzene-fused cyclic compounds bearing a quaternary stereocenter in high enantioselectivities. Notably, this reaction avoids the use of pregenerated organometallics and demonstrates high tolerance of sensitive functionalities. The preliminary mechanistic investigations reveal that this Ni-catalyzed reaction proceeds as a cascade consisting of migratory insertion and cross-coupling with a nickel(I)-mediated intramol. 5-exo cyclization as the enantiodetermining step. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Reference of 4457-67-4).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Reference of 4457-67-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary