Tag: 100-200

Mild conversion of β-diketone and β-ketoesters to carboxylic acids was written by Zhang, Yang;Jiao, Jingliang;Flowers, Robert A. II. And the article was included in Journal of Organic Chemistry in 2006.Recommanded Product: 1-Bromo-6-methoxyhexane This article mentions the following:

A mild protocol for the conversion of β-ketoesters and β-diketone to carboxylic acids with use of CAN in CH₃CN was described. The method was compatible with a number of functional groups, and could generate carboxylic acids under neutral conditions at room temperature The reaction was fast and general, providing an alternative method to the commonly used malonic ester acid preparation Initial mechanistic studies showed that initial oxidation of the enol form of the β-dicarbonyl initiated the reaction. The presence of nitrate as an oxidant ligand or as an additive was critical for success of the reaction. In the experiment, the researchers used many compounds, for example, 1-Bromo-6-methoxyhexane (cas: 50592-87-5Recommanded Product: 1-Bromo-6-methoxyhexane).

1-Bromo-6-methoxyhexane (cas: 50592-87-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Recommanded Product: 1-Bromo-6-methoxyhexane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Studies on prostaglandins. VI. Synthesis of 16(S)-methyl-20-methoxy-PGE₂ (YPG-209) having oral bronchodilator activity and its analogs was written by Iwamoto, Hidenori;Inukai, Noriyoshi;Yanagisawa, Isao;Ishii, Yoshio;Tamura, Toshinari;Shiozaki, Tetsuya;Takagi, Tokuichi;Tomioka, Kenichi;Murakami, Masuo. And the article was included in Chemical & Pharmaceutical Bulletin in 1980.HPLC of Formula: 4457-67-4 This article mentions the following:

16(S)-Methyl-2-methoxy-PGE₂ (I), 16(R)-methyl-2-methoxy-PGE₂ (II) and several analogs, such as 16(S)-methyl-20-methoxy-PGA₂ and -PGB₂, 16-methyl-20-ethoxy-PGE₂, 16-methyl-20-(hydroxymethyl)-PGE₂, 16-methyl-17-oxa-ω-dihomo-PGE₂, and 20-(hydroxymethyl)-PGE₂, were prepared I and II had potent oral bronchodilator activity; the bronchoselectivity of I was higher than that of II. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4HPLC of Formula: 4457-67-4).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.HPLC of Formula: 4457-67-4

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Interchain hydrogen-bonded conjugated polymer for enhancing the stability of organic solar cells was written by Yang, Nam Gyu;Jeon, Sung Jae;Kim, Young Hoon;Lee, Hyoung Seok;Hong, Dong Hyun;Moon, Doo Kyung. And the article was included in Journal of Industrial and Engineering Chemistry (Amsterdam, Netherlands) in 2022.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione This article mentions the following:

Operational stability of organic solar cells (OSCs) is a key issue for the commercialization. In order to enhance the stability of OSCs, various strategies are being used. In this study, pyrroles and isoindigo monomers with tert-butoxycarbonyl side chains were synthesized and used to prepare a D-A-type polymer, P(TBPyTBIID), via Stille coupling. The obtained polymer dissolved readily in organic solvents, such as chloroform. However, the formation of interchain hydrogen bonds after side-chain cleavage via thermal treatment rendered the resulting polymer insoluble in organic solvents. In addition, strong π···π stacking due to face-on orientation enabled dense packing of the structure, which led to an increase in resistances to organic solvents, acid, and UV light. P(TBPyTBIID) was introduced as a UV and external protective layer, along with silver nanoparticles, at the back surface of the glass substrate. The light-soaking stability was enhanced without significantly reducing the efficiencies of the organic solar cells. This work indicates that introducing an UV blocking layer can be an effective strategy to increase the stability of organic solar cells. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5Application In Synthesis of 1-Bromopyrrolidine-2,5-dione).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Application In Synthesis of 1-Bromopyrrolidine-2,5-dione

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Inclusion of triphenylamine unit in dopant-free hole transport material for enhanced interfacial interaction in perovskite photovoltaics was written by Lee, Ji Hyeon;Jang, Min Ho;Lee, Chan Hee;Lee, Jae-Joon;Lee, Sae Youn;Jo, Jea Woong. And the article was included in Dyes and Pigments in 2022.HPLC of Formula: 128-08-5 This article mentions the following:

Dopant-free hole transport material (HTM) has been recognized as an essential material for achieving efficient and stable perovskite photovoltaics (PPVs). Currently, conjugated polymer has emerged as a promising dopant-free HTM; however, its insufficient interaction with perovskite absorbers limits an efficient interfacial passivation and charge extraction when employed in PPVs. In this study, we developed a high-performance dopant-free HTM by the partial substitution of a conjugated polymer with triphenylamine unit. The anal. of the performance of the HTM revealed that the modification of the polymer HTM using triphenylamine unit enhanced its interaction with perovskite and its passivation ability. Furthermore, an increase in the number of face-on orientated crystallites after the triphenylamine substitution enhanced the charge transport ability of the polymer HTM. Consequently, the PPVs fabricated using the triphenylamine-substituted polymer HTM exhibited a high efficiency of 20.4% and an enhanced long-term stability compared to the devices fabricated using a control polymer without triphenylamine-substitution (15.8%). In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5HPLC of Formula: 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.HPLC of Formula: 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Determination of reactivity by molecular orbital theory. Part 84. Theoretical studies of the effects of ortho-methyl substitution on S_N1 and S_N2 processes at primary and secondary benzylic carbons was written by Lee, Ikchoon;Kim, Nam Doo;Kim, Chang Kon. And the article was included in Journal of Physical Organic Chemistry in 1993.HPLC of Formula: 83902-02-7 This article mentions the following:

The effects of o-Me substitution on the transition-state (TS) structure and reactivity of S_N1 and S_N2 processes were investigated for primary and secondary benzyl (α-tert-butyl) derivatives MO theor. using the AM1 method. The o-Me groups have both stabilizing (by electron donation) and destabilizing (steric) effects on the S_N2 TS; the former prevails for the primary whereas the latter effects becomes dominant for the secondary compounds In contrast, complex interplay of the two effects are operative in the S_N1 TS of both primary and secondary derivatives leading to the reactivity order which is consistent with that observed by solvolytic experiments, o,o’-dimethyl < H < o-Me. The bond length-reactivity rule applies only for the primary benzyl S_N2 series for which steric effects are insignificant. For reactions of benzyl derivatives is general the coplanarity between the carbenium sp² center and the benzene ring, π-σ_c-x^*, is most important in stabilizing TS structure for which other structural requirements may be relaxed. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7HPLC of Formula: 83902-02-7).

2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.HPLC of Formula: 83902-02-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ether-Functionalized Pyrrolidinium-Based Room Temperature Ionic Liquids: Physicochemical Properties, Molecular Dynamics, and the Lithium Ion Coordination Environment was written by Yoshii, Kazuki;Uto, Takuya;Onishi, Takakazu;Kosuga, Daichi;Tachikawa, Naoki;Katayama, Yasushi. And the article was included in ChemPhysChem in 2021.Computed Properties of C5H11BrO This article mentions the following:

The physicochem. properties of room temperature ionic liquids (RTILs) consisting of bis(trifluoromethanesulfonyl)amide (TFSA^–) combined with 1-hexyl-1-methylpyrrolidinium (Pyr_1,6⁺), 1-(butoxymethyl)-1-methylpyrrolidinium (Pyr_1,1O4⁺), 1-(4-methoxybutyl)-1-Me pyrrolidinium (Pyr1,4O1⁺), and 1-((2-methoxyethoxy)methyl)-1-methylpyrrolidinium (Pyr_1,1O2O1⁺) were investigated using both exptl. and computational approaches. Pyr_1,1O2O1TFSA, which contains two ether oxygen atoms, showed the lowest viscosity, and the relationship between its physicochem. properties and the position and number of the ether oxygen atoms was discussed by a careful comparison with Pyr_1,1O4TFSA and Pyr_1,4O1TFSA. Ab initio calculations revealed the conformational flexibility of the side chain containing the ether oxygen atoms. In addition, mol. dynamics (MD) calculations suggested that the ion distributions have a significant impact on the transport properties. Furthermore, the coordination environments of the Li ions in the RTILs were evaluated using Raman spectroscopy, which was supported by MD calculations using 1000 ion pairs. The presented results will be valuable for the design of functionalized RTILs for various applications. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Computed Properties of C5H11BrO).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Computed Properties of C5H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A novel anion exchange membrane based on silicone/polyphenylene oxide with excellent ionic conductivity for AEMFC was written by Liu, Qian;Wang, Zhe;Sui, Zhiyin;Shui, Tianen;Wang, Song. And the article was included in Polymers for Advanced Technologies in 2022.HPLC of Formula: 128-08-5 This article mentions the following:

To achieve good stability of anion-exchange membranes. We report an organic-inorganic composite anion exchange membrane based on polyphenylene oxide (PPO) and 3-[2-(2-aminoethylamino)ethylamino]propyl-trimethoxysilane to improve dimensional stability and mech. stability without affecting ionic conductivity The successful synthesis of the membranes was confirmed by FT-IR, 1H NMR, and EDX. The SiOSi three-dimensional network cross-linked structure was formed inside the anion-exchange membranes by added inorganic fillers. It suppressed the swelling behavior of the membrane after water uptake, with water uptake rate of 48.2%-55.6% and swelling rate of 3.1%-14.2%. It improved the mech. strength of the membranes with tensile strength of 33.5-37.8 MPa as the ratio of the membrane structure varied. Meanwhile, the flexible chain segments in the polymer structure contributed to the formation of microscopic phase separation structures, and the constructed ion-conducting channels enabled QPPO-Si-5 to reach the highest hydroxide ion conductivity of 78.7 mS/cm at 80°C (ion exchange capacity [IEC] value of 1.2 mmol/g). QPPO-Si-1 exhibited better long-term chem. stability, retaining 48.3% of the initial conductivity (30.8 mS/cm) after 600 h of alkali stability testing at 80°C in 1 M KOH solution In conclusion, the results of this study provide a facile synthetic strategy with improved membrane′s comprehensive performance. In the experiment, the researchers used many compounds, for example, 1-Bromopyrrolidine-2,5-dione (cas: 128-08-5HPLC of Formula: 128-08-5).

1-Bromopyrrolidine-2,5-dione (cas: 128-08-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.HPLC of Formula: 128-08-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Development of 5-silylethynyl-1,3-dioxolan-4-one as a new prochiral template for asymmetric phase-transfer catalysis was written by Hashimoto, Takuya;Fukumoto, Kazuhiro;Abe, Naoyuki;Sakata, Kazuki;Maruoka, Keiji. And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2010.Formula: C9H11Br This article mentions the following:

Phase-transfer catalyzed asym. alkylation and Michael addition of 5-silylalkynyl-1,3-dioxolan-4-one were developed as a novel strategy to provide highly modular tertiary α-alkyl-α-hydroxy acids bearing an alkyne moiety. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7Formula: C9H11Br).

2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Formula: C9H11Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

3-Hydroxy-4-arylsulfonyltetrahydropyranyl-3-hydroxamic acids are novel inhibitors of MMP-13 and aggrecanase was written by Noe, Mark C.;Snow, Sheri L.;Wolf-Gouveia, Lilli A.;Mitchell, Peter G.;Lopresti-Morrow, Lori;Reeves, Lisa M.;Yocum, Sue A.;Liras, Jennifer L.;Vaughn, Marcie. And the article was included in Bioorganic & Medicinal Chemistry Letters in 2004.Computed Properties of C9H11Br This article mentions the following:

N-Hydroxy-3-hydroxy-4-arylsulfonyltetrahydropyranyl-3-carboxamides were designed as novel inhibitors of MMP-13 and aggrecanase based on known endocyclic hydroxamate inhibitors of matrix metalloproteinases. These compounds offer favorable physicochem. properties and low metabolic clearance. Synthesis and structure-activity relationships are reported. In the experiment, the researchers used many compounds, for example, 2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7Computed Properties of C9H11Br).

2-(Bromomethyl)-1,3-dimethylbenzene (cas: 83902-02-7) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Computed Properties of C9H11Br

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One-Pot Synthesis of Fully Conjugated Amphiphilic Block Copolymers Using Asymmetrically Functionalized Push-Pull Monomers was written by Ahluwalia, Gagandeep;Subbiah, Jegadesan;Mitchell, Valerie D.;Saker Neto, Nicolau;Jones, David J.. And the article was included in Macromolecules (Washington, DC, United States) in 2022.Synthetic Route of C5H11BrO This article mentions the following:

Developing a fully conjugated block copolymer with a specific mol. weight and block ratio is crucial for understanding the impact of the bulk heterojunction morphol. on device performance in organic photovoltaic devices. Herein, we have revealed a strategy to synthesize fully conjugated amphiphilic diblock copolymers in one pot by combining Suzuki and Stille pseudoliving polymerizations Our strategy was to synthesize asym. functionalized push-pull monomers as precursors for the synthesis of the donor polymer poly[4,8-bis(5-(2-ethylhexyl)-4-hexylthiophene-2-yl)-benzo[1,2-b:4,5b’]dithiophenebenzo [c][1,2,5]thiadiazole] p(BDT-BT) and the acceptor polymer poly[N,N’-bis(2-octyldodecyl)-naphthalene-1,4,5,8-bis(dicarboximide)-2,6-diyl]-alt-5,5′-(2,2′-bithiophene) p(NDI-TT). The acceptor monomer (M1) was synthesized with tributyltin and triflate functionalities, whereas the donor monomer (M2) was prepared with MIDA boronate and bromide groups. These heterobifunctional acceptor and donor monomers were suitable for Stille and Suzuki polymerizations, resp. Initially, TfOPh-p(NDI-TT) was synthesized by pseudoliving Stille polymerization with a single triflate (OTf) end group and specific mol. weight Subsequently, TfOPh-p(NDI-TT) was used as a macroinitiator to grow an amphiphilic diblock copolymer (BCP1) via a grafting-into approach, where the donor polymer block was grown using pseudoliving Suzuki polymerization Lastly, one-pot synthesis of the amphiphilic diblock copolymer (BCP2) was established using optimized conditions developed for stepwise block copolymer synthesis. In the experiment, the researchers used many compounds, for example, 1-Bromo-4-methoxybutane (cas: 4457-67-4Synthetic Route of C5H11BrO).

1-Bromo-4-methoxybutane (cas: 4457-67-4) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Synthetic Route of C5H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary