Tag: 100-200

《Conductivity properties of selected aliphatic monocarboxylic acid anions in water at 298.15 K》 was published in International Journal of Electrochemical Science in 2020. These research results belong to Kinart, Zdzislaw; Tomas, Renato. Synthetic Route of C4H7BrO2 The article mentions the following:

The article presents the elec. conductivity values of sodium salts of four selected monocarboxylic acid derivatives in aqueous solution: those with a chlorine substituent in the peripheral position, i.e. ClCH(CH2)nCOOH; those with a bromine substituent in the peripheral position, i.e. BrCH(CH2)nCOOH; as well as unsaturated sodium salts with a double bond in the peripheral position, i.e. CH2 = CH(CH2)nCOOH; and unsaturated sodium salts with a double bond in the second position, i.e. CH3-CH = CH(CH2)nCOOH. All conductivity measurements were performed at 298.15 K in the concentration range of 0.0005 < c / mol · dm-3 < 0.018. The obtained values allowed the limiting molar conductivities (Λ0m) of the studied electrolytes to be determined using the Fuoss-Justice equation. Based on these (Λ0m) values, the molar limiting conductivity values (λ0A-) for individual anions of the tested electrolytes were calculated and analyzed as a function of carbon chain length. The work also examines the effect of substituent type (Cl or Br) and double bond location on the limiting molar conductivity values of the tested monocarboxylic acid anions and compares them with literature values.4-Bromobutanoic acid(cas: 2623-87-2Synthetic Route of C4H7BrO2) was used in this study.

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Synthetic Route of C4H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《A Simple 3D-Printed Enzyme Reactor Paper Spray Mass Spectrometry Platform for Detecting BuChE Activity in Human Serum》 were Yang, Yanmei; Liu, Huimin; Chen, Zhenzhen; Wu, Tianhong; Jiang, Zhongyao; Tong, Lili; Tang, Bo. And the article was published in Analytical Chemistry (Washington, DC, United States) in 2019. Application In Synthesis of 4-Bromobutanoic acid The author mentioned the following in the article:

To achieve personalized healthcare, a quick, accurate, and high-throughput method to detect disease biomarkers is essential. In the traditional practice, mass spectrometry is one of the most powerful tools and is widely studied. However, the test of human serum usually requires complicated sample pretreatment, tedious operations, and precise condition control, especially for the detection of enzymes as biomarkers. As butyrylcholinesterase (BuChE) has an indicative significance in detecting degenerative disease, liver injury, and organophosphate poisoning, the quick quantification of BuChE is of vital importance to the clinic. In this paper, we report the design and fabrication of a portable 3D-printed enzyme reactor paper spray cartridge (3D ER-PS) with integrated functions: temperature control, enzyme reaction, analyte transfer, and paper spray ionization. Coupled with mass spectrometry, quant. testing of BuChE activity in human serum was realized conveniently and accurately. While it only requires very simple sample preparation, the results from current 3D ER-PS approach are well consistent with those obtained using Ellman’s method. This 3D ER-PS platform not only provides a novel solution for the liquid biopsy of BuChE in clinics but also contributes to the development of quick and targeted medical approaches for analyzing other types of serum biomarker mols. in the field of disease diagnosis. In the experimental materials used by the author, we found 4-Bromobutanoic acid(cas: 2623-87-2Application In Synthesis of 4-Bromobutanoic acid)

4-Bromobutanoic acid(cas: 2623-87-2) belongs to carboxylic acids. The chief chemical characteristic of the carboxylic acids is their acidity. They are generally more acidic than other organic compounds containing hydroxyl groups but are generally weaker than the familiar mineral acids (e.g., hydrochloric acid, HCl, sulfuric acid, H2SO4, etc.).Application In Synthesis of 4-Bromobutanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Huang, Binbin; Li, Yanan; Yang, Chao; Xia, Wujiong. Quality Control of (Bromomethyl)cyclopropane. The article was titled 《Electrochemical 1,4-reduction of α,β-unsaturated ketones with methanol and ammonium chloride as hydrogen sources》. The information in the text is summarized as follows:

A sustainable, chemoselective 1,4-reduction of α,β-unsaturated ketones by means of an electrochem. method is presented, wherein the extremely inexpensive ammonium chloride (NH4Cl) is applied as the only additive. The reaction proceeds smoothly in the air at ambient temperature Mechanistic studies reveal that both NH4Cl and solvent methanol work as hydrogen donors. In the part of experimental materials, we found many familiar compounds, such as (Bromomethyl)cyclopropane(cas: 7051-34-5Quality Control of (Bromomethyl)cyclopropane)

(Bromomethyl)cyclopropane(cas: 7051-34-5) is used as a synthetic building block for the introduction of the cyclopropylmethyl group. It was also used in the synthesis of 1,4-dienes via iron-catalyzed cross-coupling with alkenyl Grignard reagents.Quality Control of (Bromomethyl)cyclopropane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jeong, Myeonggyo; Kang, Seongeun; Torikai, Kohei; Lee, Songyi; Yun, Hwayoung published an article in 2021. The article was titled 《A New Julia-Kocienski Reagent for Convenient Access to the 2-Naphthylmethyl Vinyl Ethers》, and you may find the article in Organic Preparations and Procedures International.Safety of o-Bromobenzaldehyde The information in the text is summarized as follows:

A facile method for the preparation of α-naphthylmethyloxy benzothiazol-2-yl-sulfone I as a new Julia-Kocienski reagent has been developed. This modified reagent converted to be useful to prepare several 2-naphthylmethyl vinyl ethers II (R = H, 4-OMe, 4-F, 2-Br) . In the part of experimental materials, we found many familiar compounds, such as o-Bromobenzaldehyde(cas: 6630-33-7Safety of o-Bromobenzaldehyde)

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Safety of o-BromobenzaldehydeIt is also used in L-threonine aldolase-catalyzed enantio and diastereoselective aldol reactions. Further, it reacts with trichloromethane to prepare 1-(2-bromo-phenyl)-2,2,2-trichloro-ethanol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Correction: A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery [Erratum to document cited in CA172:249831]》 were Zeng, Xiaodong; Xue, Liru; Chen, Deliang; Li, Shanshan; Nong, Jinxia; Wang, Bo; Tang, Lin; Li, Qianqian; Li, Yang; Deng, Zixin; Hong, Xuechuan; Wu, Mingfu; Xiao, Yuling. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Application In Synthesis of Methyl 3-bromopropanoate The author mentioned the following in the article:

In the published article Liru Xue’s name was not correctly shown; the correction is provided here.Methyl 3-bromopropanoate(cas: 3395-91-3Application In Synthesis of Methyl 3-bromopropanoate) was used in this study.

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Application In Synthesis of Methyl 3-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《A bright NIR-II fluorescent probe for breast carcinoma imaging and image-guided surgery》 were Zeng, Xiaodong; Xie, Liru; Chen, Deliang; Li, Shanshan; Nong, Jinxia; Wang, Bo; Tang, Lin; Li, Qianqian; Li, Yang; Deng, Zixin; Hong, Xuechuan; Wu, Mingfu; Xiao, Yuling. And the article was published in Chemical Communications (Cambridge, United Kingdom) in 2019. Synthetic Route of C4H7BrO2 The author mentioned the following in the article:

A novel bright near-IR II (NIR-II, 1000-1700 nm) fluorescent probe with excellent water-solubility, superior photostability, and excellent in vitro and in vivo biocompatibility was facilely synthesized for in vivo biomedical imaging of xenograft breast tumor and chem. induced spontaneous breast carcinoma. To the best of our knowledge, it is the first time that the superior practical applications of this NIR-II probe in dimethylbenzanthracene (DMBA)-induced rat mammary carcinoma imaging and image-guided rat carcinoma surgery were demonstrated. In the experiment, the researchers used Methyl 3-bromopropanoate(cas: 3395-91-3Synthetic Route of C4H7BrO2)

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact.Synthetic Route of C4H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: Ethyl 4-bromobutyrateIn 2022 ,《Solvatochromic spiropyran – a facile method for visualized, sensitive and selective response of lead (Pb2+) ions in aqueous solution》 was published in Journal of Photochemistry and Photobiology, A: Chemistry. The article was written by Liu, Guojie; Li, Yiwei; Cui, Congcong; Wang, Min; Gao, He; Gao, Jun; Wang, Jingbo. The article contains the following contents:

1′-(4′-carboxybutyl) -3′, 3′-dimethyl-6-nitro-8-hydroxylspiro [chromene-2, 2′-indoline] (SPC) is a visual, selective, and sensitive detector to lead (Pb2+) ions. The presence of 8 -hydroxyl in pyran ring makes SPC have a remarkable solvatochromism in polar solvents (SPC can isomerize to the ring-opening body (Mcc) spontaneously under visible light conditions), ascribed to the formation of intramol. hydrogen bonds. The color and spectrum of the Mcc solution could be changed instantly and significantly by addition of Pb2+, and Mcc showed excellent selectivity to Pb2+ in the simulated lead-zinc ore leachate. The complex Mcc – Pb2+, with a stoichiometry ratio of 1:1, can stably exist under visible light conditions, which is attributed to the interaction between Pb2+ and the deprotonated carboxy (-COO-), phenolic oxygen atom and 8-hydroxyl of the Mcc, and the whole process does not need UV irradiation, avoiding the serious photo-degradation of spiropyran derivatives The low limit of detection (0.61 μM) and the established test strips indicate that SPC has the potential to be applied in the quant. detection of Pb2+ in real samples.Ethyl 4-bromobutyrate(cas: 2969-81-5Recommanded Product: Ethyl 4-bromobutyrate) was used in this study.

Ethyl 4-bromobutyrate(cas: 2969-81-5) belongs to bromides. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: Ethyl 4-bromobutyrate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Kumar, Sandeep; Gupta, Sujeet Kumar published their research in World Journal of Pharmacy and Pharmaceutical Sciences in 2021. The article was titled 《Synthesis, characterization & biological activity of some N9 -(arylidene acetylhydrazino)-carbazole novel carbazole derivative》.Application of 6630-33-7 The article contains the following contents:

Synthesized six new derivatives of carbazole I[ R = 4-Cl, 4-NO2, 3-Br] test them for their anti-inflammatory activity using the carrageenan induced inflammation model in rat paw edema model. In scheme synthesized N-(chloroacetyl)-carbazole then react with hydrazine hydrate to give N-(hydrazinoacetyl)-carbazole were further reacted with various substituted aldehyde in the presence of ethanol and dioxan and found to six derivative of carbazole I. The structure of final product were confirmed by FTIR and 1H NMR. Value of FTIR, 1H NMR and thin layer chromatog. were found to be significant. All biol. activity screening by carrageenan induced inflammation in rat hind paw edema model. The compound I[ R = 3-Cl, 2-Br] most potent compound with compared to Diclofenc.o-Bromobenzaldehyde(cas: 6630-33-7Application of 6630-33-7) was used in this study.

o-Bromobenzaldehyde(cas: 6630-33-7) is used in L-threonine aldolase-catalyzed enantio/diastereoselective aldol reactions.Application of 6630-33-7It is a key starting material in the total synthesis of an anticancer agent, (-)-taxol.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Song, Ningning; Yao, Hongyan; Ma, Tengning; Wang, Tianjiao; Shi, Kaixiang; Tian, Ye; Zou, Yongcun; Zhu, Shiyang; Zhang, Yunhe; Guan, Shaowei published an article in Chemical Engineering Journal (Amsterdam, Netherlands). The title of the article was 《Fabrication of microporous polyimide networks with tunable pore size and high CO2 selectivity》.COA of Formula: C6H5BrO2 The author mentioned the following in the article:

Developing porous organic polymer materials with plenty micropores is of great importance for highly selective CO2 capture under ambient conditions. Here, to tune the pore size, two novel microporous hyperbranched polyimide networks, in which the distance between the polymer skeleton and crosslinking points is different, are successfully prepared by a two-step pathway combining polymerization and crosslinking reaction. It is intriguingly found that both porosity and CO2 sorption performance of microporous hyperbranched polyimides can be finely tuned by reducing the distance between the polymer skeleton and crosslinking points from PEPHQDA-HBPI-CL to PEQDA-HBPI-CL. The micropore size decrease from 1.18 nm to 0.86 nm, and CO2 adsorption capacity increase from 6.38 to 6.51 wt% (298 K and 1 bar). More excitingly, the PEQDA-HBPI-CL demonstrates the high CO2/N2 and CO2/CH4 selectivity up to 109 and 15 (273 K, 1 bar) according to the Henry’s law, which are superior to those of many other microporous organic polymers and among the best results for porous inorganic/ organic materials. This work reveals that the shorter-distance between the polymer skeleton and crosslinking points is in favor of fabricating microporous hyperbranched polyimide networks with abundant smaller micropore and high CO2 selectivity, which are crucial importance for the CO2 capture and storage. In addition to this study using 2-Bromobenzene-1,4-diol, there are many other studies that have used 2-Bromobenzene-1,4-diol(cas: 583-69-7COA of Formula: C6H5BrO2) was used in this study.

2-Bromobenzene-1,4-diol(cas: 583-69-7) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Some of these compounds are identical to man-made organobromine compounds, such as methyl bromide, bromoform, and bromophenols, but many others are entirely new moleclar entities, often possessing extraordinary and important biological properties. COA of Formula: C6H5BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: Methyl 3-bromopropanoateIn 2019 ,《Rational Design of a Multifunctional Molecular Dye with Single Dose and Laser for Efficiency NIR-II Fluorescence/Photoacoustic Imaging Guided Photothermal Therapy》 appeared in Analytical Chemistry (Washington, DC, United States). The author of the article were Zhang, Ruiping; Wang, Zhenjun; Xu, Liying; Xu, Yuling; Lin, Yi; Zhang, Ying; Sun, Yao; Yang, Guangfu. The article conveys some information:

Multifunctional probes integrating accurate multi-diagnosis and efficient therapy hold great prospect in biomedical research. However, the sophisticated construction and difficulties in matching the ratios of doses and laser triggers of probes for each modality imaging and therapy are still hindered the extensive practice of multifunctional probes in biomedicine. We herein rational designed an organic dye SY1080 with intrinsic multifunction by both introducing 3,4-ethylenedioxy thiophene (EDOT) and the selenium containing acceptor unit into the backbone to balance the fluorescence brightness and emission wavelength. Under single dose and 808 nm laser irradiation conditions, SY1080 not only carried out NIR-II fluorescence/Photoacoustic imaging of real-time and noninvasive tumor delineation with excellent contrast, but also effectively ablated tumors with laser irradiation to perform PTT under the guidance of dual-modal imaging. These exciting results highlighted SY1080 as a multifunctional and universal phototheranostic platform for potential applications. In the part of experimental materials, we found many familiar compounds, such as Methyl 3-bromopropanoate(cas: 3395-91-3Recommanded Product: Methyl 3-bromopropanoate)

Methyl 3-bromopropanoate(cas: 3395-91-3) belongs to bromides. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: Methyl 3-bromopropanoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary