Tag: 1500-1600

Supramolecular glycopolymers with thermo-responsive self-assembly and lectin binding was written by Cakir, Nese;Hizal, Gurkan;Becer, C. Remzi. And the article was included in Polymer Chemistry in 2015.Application of 53784-83-1 This article mentions the following:

Incorporating monomers into sequence-defined synthetic macromols. endows them to mimic nature which results in key residues being anchored in the mol. recognition pattern. Developing controlled carbohydrate sequences has critical importance in understanding the multivalent binding motifs of oligosaccharide and sequence-controlled glycopolymers to various lectins. Here, we describe the development of thermo-responsive copolymer scaffolds bearing adamantane groups that enable the formation of an inclusion complex with mono and hepta mannosylated-cyclodextrin mols. through host-guest interaction. We have demonstrated the synthesis of a triblock copolymer via RAFT polymerization, the complexation of the adamantane containing a thermoresponsive copolymer and α-D-mannose-CD, as well as their interactions with Con A. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Application of 53784-83-1).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Application of 53784-83-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Self-assembling systems of the amphiphilic cationic per-6-amino-β-cyclodextrin 2,3-di-O-alkyl ethers was written by Parrot-Lopez, Helene;Ling, Chang Chun;Zhang, Ping;Baszkin, Adam;Albrecht, Genevieve;De Rango, Colette;Coleman, Anthony W.. And the article was included in Journal of the American Chemical Society in 1992.SDS of cas: 53784-83-1 This article mentions the following:

Cationic amphiphilic cyclodextrin derivatives having an ammonium group in the 6-position and fourteen hexyl or dodecyl chains linked by ether couplings at the secondary face, have been prepared Monolayers of these compounds at the air-water interface are stable, the incompressible and tightly packed films give a mol. cross-sectional area of 260 Ų. In THF large aggregates of 350 nm diameter are observed by light scattering, for the di-dodecyl derivative Variable temperature ¹H NMR studies show clear differentiation between the temperature dependent mobility of the O2 and O3 alkyl chains. The di-hexyl ether forms a complex with N-acetylphenylalanine in chloroform-d. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1SDS of cas: 53784-83-1).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.SDS of cas: 53784-83-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Electronic transport between Au surface and scanning tunnelling microscope tip via a multipodal cyclodextrin host-metallo-guest supramolecular system was written by Kylloenen, Lasse E. P.;Chinuswamy, Viswanathan;Maffeo, Davide;Kefalas, Evangelos T.;Haider, Johanna M.;Pikramenou, Zoe;Mavridis, Irene M.;Yannakopoulou, Konstantina;Glezos, Nikos. And the article was included in Journal of Physical Organic Chemistry in 2012.Related Products of 53784-83-1 This article mentions the following:

An elementary supramol. conducting system was constructed using a novel (±)-thioctic acid-functionalized β-cyclodextrin host deposited on a gold (Au) surface and an iridium-bearing guest mol. with biphenyl tails to insert specifically into the cyclodextrin cavity. The resulting supramol. system was used to investigate remote electron communication between the flat Au surface and the platinum (Pt)/iridium (Ir) tip of a scanning tunnelling microscope. The morphol. of the surfaces after successive deposition of host mols. followed by guest mols. was investigated. Formation of features of 2 nm size was shown on the Au surface functionalized with the supramol. system. I-V spectroscopic anal. of the tunnelling current through this supramol. layer revealed the relation between the effective barrier height and tunnelling distance. Thus, in the supramol. host-metallo-guest system, a small increase of conductance is observed, compared to the layer without the guest. This can be attributed to the presence of the Ir-guest, which eventually creates intermediate energy states between the Au substrate and the Pt/Ir tip. Copyright © 2011 John Wiley & Sons, Ltd. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Related Products of 53784-83-1).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Related Products of 53784-83-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Direct synthesis of amphiphilic α-, β-, and γ-cyclodextrins was written by Chmurski, Kazimierz;Coleman, Antony W.;Jurczak, Janusz. And the article was included in Journal of Carbohydrate Chemistry in 1996.Electric Literature of C42H63Br7O28 This article mentions the following:

The clean one step synthesis of the amphiphilic α-, β-, and γ-cyclodextrins starting from per-(6-bromo-6-deoxy)-α-, -β-, and -γ-cyclodextrins is described. The role of the lipophilic tail is played by various aryl groups (Ph, p-bromophenyl, p-O-butoxyphenyl, p-pentylphenyl, and o-, m-, and p-nitrophenyl) linked by a thioether bridge to the position C-6 of each glucopyranose unit. The yields of the S-alkylation reactions were very high (85-95%). In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Electric Literature of C42H63Br7O28).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Electric Literature of C42H63Br7O28

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Polycationic Amphiphilic Cyclodextrins for Gene Delivery: Synthesis and Effect of Structural Modifications on Plasmid DNA Complex Stability, Cytotoxicity, and Gene Expression was written by Diaz-Moscoso, Alejandro;Le Gourrierec, Loeic;Gomez-Garcia, Marta;Benito, Juan M.;Balbuena, Patricia;Ortega-Caballero, Fernando;Guilloteau, Nicolas;Di Giorgio, Christophe;Vierling, Pierre;Defaye, Jacques;Ortiz Mellet, Carmen;Fernandez, Jose M. Garcia. And the article was included in Chemistry – A European Journal in 2009.Application of 53784-83-1 This article mentions the following:

A mol.-diversity-oriented approach for the preparation of well-defined polycationic amphiphilic cyclodextrins (paCDs) as gene-delivery systems is reported. The synthetic strategy takes advantage of the differential reactivity of primary vs. secondary hydroxyl groups on the CD torus to regioselectively decorate each rim with cationic elements and lipophilic tails, resp. Both the charge d. and the hydrophobic-hydrophilic balance can be finely tuned in a highly sym. architecture that is reminiscent of both cationic lipids and cationic polymers, the two most prominent types of nonviral gene vectors. The monodisperse nature of paCDs and the modularity of the synthetic scheme are particularly well suited for structure-activity relationship studies. Gel electrophoresis revealed that paCDs self-assemble in the presence of plasmid DNA (pDNA) to provide homogeneous, stable nanoparticles (CDplexes) of 70-150 nm that fully protect pDNA from the environment. The transfection efficiency of the resulting CDplexes has been investigated in vitro on BNL-CL2 and COS-7 cell lines in the absence and presence of serum and found to be intimately dependent on architectural features. Facial amphiphilicity and the presence of a cluster of cationic and hydrogen-bonding centers for cooperative and reversible complexation of the polyanionic DNA chain is crucial to attain high transgene expression levels with very low toxicity profiles. Further enhancement of gene expression, eventually overcoming that of polyplexes from com. polyethyleneimine (PEI) polymers (22 kDa), is achieved by building up space-oriented dendritic polycationic constructs. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Application of 53784-83-1).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Application of 53784-83-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Monodisperse nanoparticles from self-assembling amphiphilic cyclodextrins: modulable tools for the encapsulation and controlled release of pharmaceuticals was written by Mendez-Ardoy, Alejandro;Gomez-Garcia, Marta;Geze, Annabelle;Putaux, Jean-Luc;Wouessidjewe, Denis;Mellet, Carmen Ortiz;Defaye, Jacques;Fernandez, Jose M. Garcia;Benito, Juan M.. And the article was included in Medicinal Chemistry in 2012.Reference of 53784-83-1 This article mentions the following:

Selective chem. functionalization of cyclodextrins (CDs) is a readily amenable methodol. to produce amphiphilic macromols. endowed with modulable self-organizing capabilities. Herein, the synthesis of well-defined amphiphilic CD derivatives, with a “skirt-type” architecture, that incorporate long-chain fatty esters at the secondary hydroxyl rim and a variety of chem. functionalities (e. g. iodo, bromo, azido, cysteaminyl or isothiocyanato) at the primary hydroxyls rim is reported. Nanopptn. of the new CD facial amphiphiles, or binary mixtures of them, resulted in nanoparticles with average hydrodynamic diameters ranging from 100 to 240 nm that were stable in suspension for several months. The precise size, zeta potential and topol. of the nanoparticles are intimately dependent on the functionalization pattern at the CD scaffold. Highly efficient mol. encapsulation capabilities of poorly bioavailable drugs such as diazepam (DZ) were demonstrated for certain derivatives, the drug release profile being dependent on the type of formulation (nanospheres or nanocapsules). The efficiency and versatility of the synthetic strategy, together with the possibility of exploiting the reactivity of the functional groups at the nanoparticle surface, offer excellent opportunities to further manipulate the carrier capabilities of this series of amphiphilic CDs from a bottom-up approach. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Reference of 53784-83-1).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Reference of 53784-83-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Phosphorylation of per-6-bromo-per-6-deoxy-β-cyclodextrin was written by Grachev, M. K.;Mustafin, I. G.;Nifant’ev, E. E.. And the article was included in Russian Journal of General Chemistry (Translation of Zhurnal Obshchei Khimii) in 1998.Safety of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin This article mentions the following:

Phosphorylation of per-6-bromo-per-6-deoxy-β-cyclodextrin with alkylene phosphochloridites was studied with the aim of preparing phosphorus-containing cyclodextrins substituted with polar groups and capable of definite orientation on an organic liquid-water phase boundary. The bromodeoxy derivative of β-cyclodextrin alkylates pyridine with a high yield to give the corresponding pyridinium salts readily soluble in water and polar solvents. Trimethylsilyl derivatives of β-cyclodextrin were obtained, which are highly soluble in organic solvents and are regioselectively phosphorylated with phosphochloridites. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Safety of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Safety of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Investigation of the Adsorption of Gaseous Aromatic Compounds at Surfaces Coated with Heptakis(6-thio-6-deoxy)-β-cyclodextrin by Surface-Enhanced Raman Scattering was written by Hill, Wieland;Fallourd, Valerie;Klockow, Dieter. And the article was included in Journal of Physical Chemistry B in 1999.Application of 53784-83-1 This article mentions the following:

Heptakis(6-thio-6-deoxy)-β-cyclodextrin (TCD) was prepared and chemisorbed at the surface of rough silver substrates for surface-enhanced Raman scattering (SERS). The enhanced adsorption of methyl orange and the stability of its azo form at the TCD-coated substrates proved the capability of the immobilized TCD to form inclusion complexes with organic guest mols. This complexation was used for the detection of aromatics in the gas phase. Toluene, ethylbenzene, m-xylene, chlorobenzene, and m-dichlorobenzene were strongly adsorbed at the TCD-coated substrates, thus making possible the detection of low concentrations, as for example 15 ppm of m-dichlorobenzene. Benzene was weakly adsorbed and detectable in high concentrations only. Since the strongly adsorbed aromatics desorb very slowly, TCD-coated substrates may be applicable for the detection of slowly changing concentrations or as integrating sensors in the surveillance of chem. exposures. The capability of immobilized TCD to adsorb also polycyclic aromatic hydrocarbons was demonstrated using naphthalene. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Application of 53784-83-1).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Application of 53784-83-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The β-cyclodextrin cationic derivatives containing residues of some pharmacologically important acids was written by Grachev, M. K.;Charaev, A. A.;Kurochkina, G. I.;Vasyanina, L. K.;Shmelev, V. N.;Nifant’ev, E. E.. And the article was included in Russian Journal of General Chemistry in 2010.COA of Formula: C42H63Br7O28 This article mentions the following:

The cationic derivatives of β-cyclodextrin containing residues of covalently bound pharmacol. important acids were obtained by alkylation of nucleophilic reagents with 6-halo-6-deoxy-β-cyclodextrin. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1COA of Formula: C42H63Br7O28).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. COA of Formula: C42H63Br7O28

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A convenient procedure for the formation of per(6-deoxy-6-halo)cyclodextrins using the combination of tetraethylammonium halide with [Et₂NSF₂]BF₄ was written by Liu, Xiaofeng;Cheng, Sen;Wang, Xiaolei;Xue, Weihua. And the article was included in Synthesis in 2013.Safety of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin This article mentions the following:

A convenient and efficient procedure for the regioselective halogenation of the primary alcs. of cyclodextrins using the reagent combination of tetraethylammonium halide with [Et₂NSF₂]BF₄ is described. In the experiment, the researchers used many compounds, for example, Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1Safety of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin).

Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin (cas: 53784-83-1) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Safety of Heptakis(6-Bromo-6-Deoxy)-β-Cyclodextrin

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary