Tag: 200-300

In 2019,Chemical Science included an article by Zhou, Jiawang; Wu, Yilei; Roy, Indranil; Samanta, Avik; Stoddart, J. Fraser; Young, Ryan M.; Wasielewski, Michael R.. Formula: C8H8Br2. The article was titled 《Choosing sides: unusual ultrafast charge transfer pathways in an asymmetric electron-accepting cyclophane that binds an electron donor》. The information in the text is summarized as follows:

Constructing functional mol. systems for solar energy conversion and quantum information science requires a fundamental understanding of electron transfer in donor-bridge-acceptor (D-B-A) systems as well as competitive reaction pathways in acceptor-donor-acceptor (A-D-A) and acceptor-donor-acceptor’ (A-D-A’) systems. Herein we present a supramol. complex comprising a tetracationic cyclophane having both phenyl-extended viologen (ExV2+) and dipyridylthiazolothiazole (TTz2+) electron acceptors doubly-linked by means of two p-xylylene linkers (TTzExVBox4+), which readily incorporates a perylene (Per) guest in its cavity (Per ⊂ TTzExVBox4+) to establish an A-D-A’ system, in which the ExV2+ and TTz2+ units serve as competing electron acceptors with different reduction potentials. Photoexcitation of the Per guest yields both TTz+·- Per+·- ExV2+ and TTz2+-Per+·-ExV+·in < 1 ps, while back electron transfer in TTz2+-Per+·-ExV+· proceeds via the unusual sequence TTz2+-Per+· -ExV+· →TTz+· -Per+· -ExV2+ → TTz2+-Per-ExV2+. In addition, selective chem. reduction of TTz2+ gives Per ⊂ TTzExVBox3+· turning the complex into a D-B-A system in which photoexcitation of TTz+· results in the reaction sequence 2*TTz+· -Per-ExV2+ → TTz2+-Per-ExV+ → TTz +· -Per-ExV2+. Both reactions TTz2+-Per+· -ExV+· → TTz+ -Per+· -ExV2+ and TTz2+-Per-ExV+· → TTz+· -Per-ExV2+ occur with a (16 ± 1 ps)-1 rate constant irresp. of whether the bridge mol. is Per+ or Per. These results are explained using the superexchange mechanism in which the ionic states of the perylene guest serve as virtual states in each case and demonstrate a novel supramol. platform for studying the effects of bridge energetics within D-B-A systems.1,4-Bis(bromomethyl)benzene(cas: 623-24-5Formula: C8H8Br2) was used in this study.

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Formula: C8H8Br2 Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,ACS Omega included an article by Panettieri, Silvio; Silverman, Julian R.; Nifosi, Riccardo; Signore, Giovanni; Bizzarri, Ranieri; John, George. Synthetic Route of C8H15BrO2. The article was titled 《Unique Photophysical Behavior of Coumarin-Based Viscosity Probes during Molecular Self-Assembly》. The information in the text is summarized as follows:

Intermol. interactions impact self-assembly phenomena with a variety of biochem., phys., and mech. consequences. Nevertheless, underlying mechanisms leading to a controlled stereo- and chemo-specific aggregation at the mol. level often remain elusive due to the intrinsically dynamic nature of these processes. This work describes two, 3-styryl coumarin mol. rotors capable of probing subtle intermol. interactions controlling self-assembly of a small mol. organogelator. Complementing the gel characterization using CD and at. force microscopy, thorough spectroscopic assessments on these sensors were conducted to prove their high chem. and spatial affinity toward the three-dimensional supramol. network. Results were also supported by mol. dynamics simulations to provide addnl. critical insights into gelator dynamic self-assembly mechanisms. These sensors could potentially serve as templates to study a variety of soft-supramol. architectures and ways in which they assemble. After reading the article, we found that the author used 8-Bromooctanoic acid(cas: 17696-11-6Synthetic Route of C8H15BrO2)

8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid.Synthetic Route of C8H15BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,ACS Catalysis included an article by Zhang, Guodong; Hu, Zhiyong; Bertoli, Giulia; Goossen, Lukas J.. Application In Synthesis of 3-Bromo-2-methylbenzoic acid. The article was titled 《Iridium-Catalyzed Synthesis of Substituted Indanones from Aromatic Carboxylates and Unsaturated Ketones》. The information in the text is summarized as follows:

A catalytic annulation is presented that provides straightforward, modular synthetic access to 3-substituted indanones from benzoic acids and α,β-unsaturated ketones. It is catalyzed by a bimetallic Ir/In system and proceeds via hydroarylation followed by Claisen condensation and optional retro-Claisen deacylation. The annulation may be combined into a one-pot procedure with the synthesis of the unsaturated ketone substrates from aldehydes and acetone. Two complementary reaction protocols are provided that are applicable to diversely functionalized electron-rich and electron-poor substrates. In the experiment, the researchers used 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Application In Synthesis of 3-Bromo-2-methylbenzoic acid)

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Most of the natural organobromine compounds are produced by marine organisms , and several brominated metabolites with antibacterial , antitumor , antiviral , and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Application In Synthesis of 3-Bromo-2-methylbenzoic acid In contrast, terrestrial plants account only for a few bromine-containing compounds.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Green Chemistry included an article by Hazra, Susanta; Kushawaha, Ajay Kishor; Yadav, Deepak; Dolui, Pritam; Deb, Mayukh; Elias, Anil J.. Quality Control of 4-Bromobenzoic acid. The article was titled 《Table salt as a catalyst for the oxidation of aromatic alcohols and amines to acids and imines in aqueous medium: effectively carrying out oxidation reactions in sea water》. The information in the text is summarized as follows:

A simple, efficient, sustainable and economical method for the oxidation of alcs. and amines was developed based on chloride, a sea abundant anionic catalyst for the practical synthesis of a wide range of carboxylic acids, ketones and imines. Oxidation of aromatic alcs. was carried out using NaCl (20 mol%) as the catalyst, NaOH (50 mol%) and aqueous TBHP (4 equivalent) as the oxidant in 55-92% isolated yields. Oxidation of aromatic amines to imines was achieved by using only 20 mol% of NaCl and aqueous TBHP (4 equivalent) in 32-93% isolated yields. The chlorine species formed during the reaction as the active oxidation catalyst was identified as ClO2- for alcs. and ClO-/ClO2- for amines by control experiments This method was mostly free from chromatog. purification, which made it suitable for large-scale synthesis. The synthesis of carboxylic acids and imines scaled up to 30 g scale in good yields and was also carried out efficiently this new method using filtered sea water as the solvent and catalyst. The experimental process involved the reaction of 4-Bromobenzoic acid(cas: 586-76-5Quality Control of 4-Bromobenzoic acid)

4-Bromobenzoic acid(cas: 586-76-5) has been used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.Quality Control of 4-Bromobenzoic acid It was used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Organic Letters included an article by Lin, Ling-Zhi; Che, Yuan-Yuan; Bai, Peng-Bo; Feng, Chao. Related Products of 5437-45-6. The article was titled 《Sulfinate-Engaged Nucleophilic Addition Induced Allylic Alkylation of Allenoates》. The information in the text is summarized as follows:

A strategically novel Pd-catalyzed nucleophilic addition induced allylic alkylation reaction (NAAA) of allenoates has been successfully accomplished. By judiciously integrating ZnCl2-promoted Michael addition with Pd-catalyzed allylic alkylation, allenoates readily undergo allyl-sunfonylation at the internal double bond, thus providing a straightforward avenue for the rapid assembly of a host of structurally diversified α-allyl-β-sufonylbut-3-enoate derivatives The success of this transformation profits from a delicate control of the reaction kinetic of each elementary step, thanks to the synergistic interaction of Pd/Zn bimetallic system, thus suppressing either direct allylic sulfonylation or premature quenching of therein in situ generated ester enolate intermediate. Furthermore, by expanding the scope of workable Michael acceptor beyond those previously required doubly activated ones, such as methylenemalononitrile, the present work substantially enriches the repertoire of NAAA reactions. In the part of experimental materials, we found many familiar compounds, such as Benzyl 2-bromoacetate(cas: 5437-45-6Related Products of 5437-45-6)

Benzyl 2-bromoacetate(cas: 5437-45-6) belongs to benzyl acetate. Benzyl acetate is a synthetic chemical produced for industry from benzyl alcohol and acetic acid, but is also naturally present in the essential oils of many plants, including jasmine and ylang ylang.Related Products of 5437-45-6

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Huang, Binbin; Guo, Lin; Xia, Wujiong published an article in 2021. The article was titled 《A facile and versatile electro-reductive system for hydrodefunctionalization under ambient conditions》, and you may find the article in Green Chemistry.Safety of 1-Bromo-3,4,5-trimethoxybenzene The information in the text is summarized as follows:

A general electrochem. system for reductive hydrodefunctionalization is described, employing the inexpensive and easily available triethylamine (Et3N) as a sacrificial reductant. This protocol is characterized by facile operation, sustainable conditions, and exceptionally wide substrate e.g., 9-bromophenanthrene scope covering the cleavage of C-halogen, N-S, N-C, O-S, O-C, C-C and C-N bonds. Notably, the selectivity and capability of reduction can be conveniently switched by simple incorporation or removal of an ethanol. as a co-solvent. In the experimental materials used by the author, we found 1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8Safety of 1-Bromo-3,4,5-trimethoxybenzene)

1-Bromo-3,4,5-trimethoxybenzene(cas: 2675-79-8) is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.Safety of 1-Bromo-3,4,5-trimethoxybenzene1-Bromo-3,4,5-trimethoxybenzene can be used to synthesize N,N′-diarylated indolo[3,2-b]carbazole derivatives, which can find applications in electrophotography.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Qi-Liang; Jia, Hong-Wei; Liu, Ying; Xing, Yi-Kang; Ma, Rui-Cong; Wang, Man-Man; Qu, Gui-Rong; Mei, Tian-Sheng; Guo, Hai-Ming published their research in Organic Letters in 2021. The article was titled 《Electrooxidative Iridium-Catalyzed Regioselective Annulation of Benzoic Acids with Internal Alkynes》.HPLC of Formula: 586-76-5 The article contains the following contents:

Electrochem. driven, Cp*Ir(III)-catalyzed regioselective annulative couplings of benzoic acids with alkynes were established herein. The combination of Ir catalyst and electricity not only circumvents the need for stoichiometric amount of chem. oxidant, but also ensures broad reaction compatibility with a wide array of sterically and electronically diverse substrates. This electrochem. approach represents a sustainable strategy as an ideal alternative and supplement to the oxidative annulations methodol. to be engaged in the synthesis of isocoumarin derivatives The experimental process involved the reaction of 4-Bromobenzoic acid(cas: 586-76-5HPLC of Formula: 586-76-5)

4-Bromobenzoic acid(cas: 586-76-5) has been used to study the metabolic fate of 2-,3-and 4-bromo benzoic acids in rat hepatocytes incubation using high temperature liquid chromatography.HPLC of Formula: 586-76-5 It was used in bromine-specific detection of the metabolites of 2-,3-and 4-bromobenzoic acid in the urine and bile of rats by inductively coupled plasma mass spectrometry.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Su, Yingbin; Miao, Yawei; Zhu, Yaowei; Zou, Wentao; Yu, Bing; Shen, Youqing; Cong, Hailin published their research in Polymer Chemistry in 2021. The article was titled 《A design strategy for D-A conjugated polymers for NIR-II fluorescence imaging》.Application of 3141-27-3 The article contains the following contents:

The development of bioimaging technol. in recent years has shown that second near-IR (NIR-II) fluorescence imaging (FI) is gradually replacing the traditional visible light and first near-IR (NIR-I) FI. In the NIR-II window, the light absorption, autofluorescence and scattering of biol. tissues are significantly reduced, which strongly promotes the design, development and application of contrast agents with NIR-II emission capabilities. However, the NIR-II bioimaging technol. is still incomplete, in the initial stage, and has high research value. In order to increase the quantum yield (QY) of D-A polymers, we used thiophene, 3-methoxythiophene, 3,4-ethylenedioxythiophene (EDOT), 3-hexylthiophene and 3-(2-ethylhexyl)thiophene as strong electron donors and designed and synthesized NIR-II organic polymers P1, P2, P3, P4 and P5, which are of great significance to the mol. design of D-A conjugated polymers. Finally, we explored the FI of the polymers in vivo and in vitro, and verified our idea of increasing the QY. In the part of experimental materials, we found many familiar compounds, such as 2,5-Dibromothiophene(cas: 3141-27-3Application of 3141-27-3)

2,5-Dibromothiophene(cas: 3141-27-3) , is mainly used as pharmaceutical intermediate and synthesis intermediate. 2,5-Dibromothiophene may be used in the preparation of soluble α,ω-diformyl-a-oligothiophenes.Application of 3141-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Ze; Zhao, Xianghua; Huang, An; Yang, Zehui; Cheng, Yuqi; Chen, Jiachen; Ling, Fei; Zhong, Weihui published their research in Tetrahedron Letters in 2021. The article was titled 《Manganese catalyzed enantio- and regioselective hydrogenation of α,β-unsaturated ketones using an imidazole-based chiral PNN tridentate ligand》.HPLC of Formula: 14516-54-2 The article contains the following contents:

The enantioselective 1,2-reduction of α,β-unsaturated ketones has been achieved using a chiral pincer Mn catalyst. A series of PNN tridentate ligands containing benzimidazole groups were designed with ferrocene as the backbone, which coordinated with Mn to form the active catalyst. This mild process represents a general method to access chiral allyl alcs. with high catalytic activity (up to 9500 TON) and high enantioselectivity (66-86% ee). Furthermore, this catalytic system provides a novel synthesis of key pharmaceutical intermediates of cannabidiol. In the experiment, the researchers used Bromopentacarbonylmanganese(I)(cas: 14516-54-2HPLC of Formula: 14516-54-2)

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.HPLC of Formula: 14516-54-2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Wang, Siyuan; Zhou, Yangkun; Huang, Hanmin published their research in Organic Letters in 2021. The article was titled 《Palladium-Catalyzed Tandem Carbonylative Diels-Alder Reaction for Construction of Bridged Polycyclic Skeletons》.Electric Literature of C8H7BrO2 The article contains the following contents:

A palladium-catalyzed tandem carbonylative lactonization and Diels-Alder cycloaddition reaction between aldehyde-tethered benzyl halides I (R1 = H, X = Cl, Br; R1 = 4-Cl, 3-Br, 5-MeO, etc., X = Br) and alkenes R2R3C:CHR4 [R2 = H, n-BuO, ClCH2CH2O, BocNH, Ph, 2-MeC6H4, 4-ClC6H4, etc., R3 = R4 = H; R2 = Ph, R3 = Me, R4 = H; R2R4 = OCH2CH2, (CH2)3, (CH2)6; etc.] has been developed. A range of alkenes and aldehyde-tethered benzyl halides bearing different substituents can be successfully transformed into the corresponding bridged polycyclic compounds II in good yields. This strategy provides a unique approach to complex lactone-containing bridged polycyclic compounds In the part of experimental materials, we found many familiar compounds, such as 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Electric Literature of C8H7BrO2)

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool. Electric Literature of C8H7BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary