Tag: 200-300

Formula: C12H15BrOOn May 2, 2005 ,《Copper-catalyzed etherification of aryl iodides using KF/Al2O3. An improved protocol》 appeared in Synlett. The author of the article were Hosseinzadeh, Rahman; Tajbakhsh, Mahmood; Mohadjerani, Maryam; Alikarami, Mohammad. The article conveys some information:

A simple and efficient method for the coupling of aryl iodides with aliphatic alcs. and phenols that does not require the use of alkoxide bases is described. This C-O bond forming procedure shows that the combination of air stable CuI and 1,10-phenanthroline in the presence of KF/Al2O3 comprises an extremely efficient and general catalyst system for the etherification of aryl iodides. Different functionalized aryl iodides were coupled with alcs. and phenols using this method. In the experimental materials used by the author, we found 1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9Formula: C12H15BrO)

1-Bromo-4-(cyclohexyloxy)benzene(cas: 30752-31-9) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Formula: C12H15BrOSome of these compounds are identical to man-made organobromine compounds, such as methyl bromide, bromoform, and bromophenols, but many others are entirely new moleclar entities, often possessing extraordinary and important biological properties.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Synthesis and mesomorphic properties of the nematic mesophase benzoxazole derivatives with big twist angle of difluoro-biphenyl unit》 was published in Liquid Crystals in 2019. These research results belong to Weng, Qiang; Duan, Longyan; Chen, Pei; Gao, Aiai; Chen, Xinbing; An, Zhongwei. COA of Formula: C8H8BrFO The article mentions the following:

Here, a series of 2-(2,2′-difluoro-4′-alkoxy-1,1′-biphenyl-4-yl)-5-substituted benzoxazoles I [R = Et, n-Bu, hexyl, etc.; R1 = H, Me, NO2] with both non-polar (H, CH3) and polar (NO2) groups (coded as nPF(2)PF(2)Bx) was synthesized and characterized. All of the compounds showed a conspicuous inter-ring twist angle of 38° compared with corresponding reference compounds which were calculated by d. functional theory method, and it was interesting to note that the final compounds I showed only nematic mesophase during heating or cooling. Meanwhile, the UV-vis absorption bands and photoluminescence emission peaks both displayed remarkable blue-shifted. The aforementioned results revealed that lateral difluoro substituents played a key role to stable the nematic mesophase by increasing the dihedral angle of biphenyl. In the part of experimental materials, we found many familiar compounds, such as 1-Bromo-4-ethoxy-2-fluorobenzene(cas: 107713-66-6COA of Formula: C8H8BrFO)

1-Bromo-4-ethoxy-2-fluorobenzene(cas: 107713-66-6) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Organobromine compounds are produced naturally by marine creatures (sponges, corals, sea slugs, tunicates, sea fans) and seaweed, plants, fungi, lichen, algae, bacteria, microbes, and some mammals. COA of Formula: C8H8BrFO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Metal-Free C-S Bond Formation in Elemental Sulfur and Cyclobutanol Derivatives: The Synthesis of Substituted Thiophenes》 was written by Wu, Mingzhong; Yan, Chaoxian; Zhuang, Daijiao; Yan, Rulong. Computed Properties of C7H5BrO2This research focused onthiophene preparation; cyclobutanol elemental sulfur bond formation. The article conveys some information:

A general approach for the metal-free synthesis of thiophenes by tert-cyclobutanols and elemental sulfur was developed. This protocol provided a strategy for constructing multisubstituted thiophene derivatives via C-S bond formation under air. This reaction showed good functionality tolerance under the reaction conditions, and the mechanism was validated by control experiments and d. functional theory calculations After reading the article, we found that the author used 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Computed Properties of C7H5BrO2)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Computed Properties of C7H5BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3,5-DibromoanilineIn 2020 ,《Tetracoordinate borates as catalysts for reductive formylation of amines with carbon dioxide》 was published in Green Chemistry. The article was written by Jiang, Xiaolin; Huang, Zijun; Makha, Mohamed; Du, Chen-Xia; Zhao, Dongmei; Wang, Fang; Li, Yuehui. The article contains the following contents:

We report sodium trihydroxyaryl borates as the first robust tetracoordinate organoboron catalysts for reductive functionalization of CO2. These catalysts, easily synthesized from condensing boronic acids with metal hydroxides, activate main group element-hydrogen (E-H) bonds efficiently. In contrast to BX3 type boranes, boronic acids and metal-BAr4 salts, under transition metal-free conditions, sodium trihydroxyaryl borates exhibit high reactivity of reductive N-formylation toward a variety of amines (106 examples), including those with functional groups such as ester, olefin, hydroxyl, cyano, nitro, halogen, MeS-, ether groups, etc. The over-performance to catalyze formylation of challenging pyridyl amines affords a promising alternative method to the use of traditional formylation reagents. Mechanistic investigation supports electrostatic interactions as the key for Si/B-H activation, enabling alkali metal borates as versatile catalysts for hydroborylation, hydrosilylation, and reductive formylation/methylation of CO2. In the experiment, the researchers used 3,5-Dibromoaniline(cas: 626-40-4Recommanded Product: 3,5-Dibromoaniline)

3,5-Dibromoaniline(cas: 626-40-4) belongs to anime. Amines characteristically form salts with acids; a hydrogen ion, H+, adds to the nitrogen. With the strong mineral acids (e.g., H2SO4, HNO3, and HCl), the reaction is vigorous. Salt formation is instantly reversed by strong bases such as NaOH. Neutral electrophiles (compounds attracted to regions of negative charge) also react with amines; alkyl halides (R′X) and analogous alkylating agents are important examples of electrophilic reagents.Recommanded Product: 3,5-Dibromoaniline

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Cationic ether-free poly(bis-alkylimidazolium) ionene blend polybenzimidazole as anion exchange membranes》 was written by Dong, Jianhao; Yu, Na; Che, Xuefu; Liu, Ruihong; Aili, David; Yang, Jingshuai. SDS of cas: 623-24-5 And the article was included in Polymer Chemistry in 2020. The article conveys some information:

Two ether-free poly(bis-alkylimidazolium) ionenes with imidazolium cations as part of the main chain were synthesized from 1,4-bis(imidazolyl)butane and 1,4-dibromobutane or 1,4-bis(bromomethyl)benzene via nucleophilic substitution polymerization Anion exchange membranes (AEMs) were prepared by co-casting with polybenzimidazole (PBI), producing visually homogeneous and mech. robust blend AEMs. The ion exchange capacity (IEC), water uptake and ion conductivity could be balanced by adjusting the molar ratio of the poly(bis-alkylimidazolium) to PBI polymer in the blend. For example, the blend AEM of PBuIm-37%/PBI prepared from the oligomer derived from 1,4-dibromobutane with an IEC of 1.36 mmol g-1 showed a tensile strength of 5.3 MPa at room temperature and a hydroxide conductivity of 74 mS cm-1 at 80 °C and excellent stability over 500 h in 1 mol L-1 KOH at 60 °C. The present work opens up a new route towards ether-free AEM design and fabrication with a wide potential structural scope. In the experimental materials used by the author, we found 1,4-Bis(bromomethyl)benzene(cas: 623-24-5SDS of cas: 623-24-5)

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool. SDS of cas: 623-24-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Behavior, mechanism and equilibrium studies of Au(III) extraction with an ionic liquid [C4-6-C4BIm]Br2》 was written by Su, Hongmei; Wang, Qi; Wang, Ning; Yang, Yanzhao. Application In Synthesis of 1,6-Dibromohexane And the article was included in Dalton Transactions in 2020. The article conveys some information:

The first gemini-type benzimidazole ionic liquid ([C4-6-C4BIm]Br2) with two sites of action was synthesized and applied for gold extraction The effects of [C4-6-C4BIm]Br2 concentration, initial gold(III) concentration, acidity, and the loading capacity of [C4-6-C4BIm]Br2 were examined in detail. It was found that [C4-6-C4BIm]Br2 has excellent extraction ability for obtaining high purity gold. The anion exchange mechanism between [C4-6-C4BIm]Br2 and Au(III) was proved by Job’s method and 1H NMR and FTIR spectroscopy. Quantum chem. calculations were carried out to prove the mechanism theor. The extraction equilibrium process was modeled using Langmuir and Freundlich isotherms. Thermodn. parameters ΔH, ΔG and ΔS indicated that the extraction process was exothermic and spontaneous. The pseudo-second-order kinetic model well fitted the exptl. data (R = 0.99). In addition, [C4-6-C4BIm]Br2 has high selectivity for Au(III) compared to other base metals. In summary, [C4-6-C4BIm]Br2 has great application prospects in industry due to its excellent characteristics such as low cost, easy availability, and high extraction capacity. After reading the article, we found that the author used 1,6-Dibromohexane(cas: 629-03-8Application In Synthesis of 1,6-Dibromohexane)

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of pyrrolo-tetrathiafulvalene molecular bridge (6PTTF6) to study redox switching behavior of single molecules; synthesis of water-soluble thermoresponsive polylactides.Application In Synthesis of 1,6-Dibromohexane

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Ligand-Enabled Pd(II)-Catalyzed C(sp3)-H Lactonization Using Molecular Oxygen as Oxidant》 was written by Qian, Shaoqun; Li, Zi-Qi; Li, Minyan; Wisniewski, Steven R.; Qiao, Jennifer X.; Richter, Jeremy M.; Ewing, William R.; Eastgate, Martin D.; Chen, Jason S.; Yu, Jin-Quan. Synthetic Route of C8H7BrO2 And the article was included in Organic Letters in 2020. The article conveys some information:

Pd(II)-catalyzed C-H lactonization of o-Me benzoic acid substrates has been achieved using mol. oxygen as the oxidant. This finding provides a rare example of C-H oxygenation through Pd(II)/Pd(0) catalysis as well as a method to construct biol. important benzolactone scaffolds. The use of a gas mixture of 5% oxygen in nitrogen demonstrated the possibility for its application in pharmaceutical manufacturing In the experiment, the researchers used many compounds, for example, 3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Synthetic Route of C8H7BrO2)

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Synthetic Route of C8H7BrO2 Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Comparative Studies of the Corrosion Inhibition Efficacy of a Dicationic Monomer and Its Polymer against API X60 Steel Corrosion in Simulated Acidizing Fluid under Static and Hydrodynamic Conditions》 was published in ACS Omega in 2020. These research results belong to Odewunmi, Nurudeen A.; Solomon, Moses M.; Umoren, Saviour A.; Ali, Shaikh A.. Application of 629-03-8 The article mentions the following:

N1,N1-diallyl-N6,N6,N6-tripropylhexane-1,6-diaminium chloride (NDTHDC) and its polymer poly(N1,N1-diallyl-N6,N6,N6-tripropylhexane-1,6-diaminium chloride) (poly-NDTHDC) were synthesized and tested against API X60 carbon steel corrosion in 15 wt % HCl solution Weight loss, electrochem., and surface anal. techniques were used. Results show that poly-NDTHDC is better than NDTHDC. Moreover, 1000 mg/L NDTHDC protected the studied surface by 79.1% at 25 °C, while 100 mg/L poly-NDTHDC afforded 86.1% protection. Inhibition efficiency increases with temperature (up to 60 °C) but depreciates thereafter. NDTHDC and poly-NDTHDC perform better under the hydrodynamic condition than the static condition. TGA and FTIR results reveal that poly-NDTHDC is chem. and thermally stable. In the experiment, the researchers used 1,6-Dibromohexane(cas: 629-03-8Application of 629-03-8)

1,6-Dibromohexane(cas: 629-03-8) is generally used to introduce C6 spacer in the molecular architecture. Some of the examples are: synthesis of solvent processable and conductive polyfluorene ionomers for alkaline fuel cell applications; synthesis of cross-linkable regioregular poly(3-(5-hexenyl)thiophene) (P3HNT) for stabilizing the film morphology in polymer photovoltaic cells.Application of 629-03-8

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《In situ conversion of rose bengal microbubbles into nanoparticles for ultrasound imaging guided sonodynamic therapy with enhanced antitumor efficacy》 was published in Biomaterials Science in 2020. These research results belong to Hou, Rui; Liang, Xiaolong; Li, Xiaoda; Zhang, Xu; Ma, Xiaotu; Wang, Fan. Application of 17696-11-6 The article mentions the following:

Sonodynamic therapy (SDT) is a prospective therapy for many tumors by activation of sonosensitizers to produce reactive oxygen species (ROS) by ultrasound (US). However, limited generation of ROS and low drug delivery efficiency of sonosensitizers to the tumor tissue still hinder the application of SDT. Herein, an amphiphilic rose bengal (ARB) conjugate was designed to fabricate rose bengal microbubbles (RB-MBs) with high drug-loading contents (~6.8%) and excellent contrast enhancement capability for US imaging, well suited for detecting tumor location and size. More importantly, RB-MBs could be successfully converted into RB-NPs by local US exposure, resulting in ~7.5 times higher drug accumulation at the tumor tissue through the sonoporation effect as compared to RB-NPs and RB-MBs without US sonication. Meanwhile, using RB as the MB shell facilitated US energy transfer by the US mediated collapse of MBs through either a sonoluminescence or pyrolysis process; thus, the ROS generation efficiency could be greatly enhanced, resulting in a significantly higher tumor inhibition rate for the RB-MBs + US (~76.5%) in the HT-29 tumor model as compared to conventional MBs + US and RB-NPs + US (~23.8% and ~49.2%), resp. All these results suggested that this novel sonosensitizer delivery system of RB-MBs combined with US is a powerful strategy for remarkably enhancing SDT therapeutic efficacy with minimal side effects, showing great potential in cancer theranostics. In the experiment, the researchers used many compounds, for example, 8-Bromooctanoic acid(cas: 17696-11-6Application of 17696-11-6)

8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid. And 8-Bromooctanoic Acid is a useful compound for sonodynamic therapy.Application of 17696-11-6

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Solar-driven tandem photoredox nickel-catalysed cross-coupling using modified carbon nitride》 was published in Chemical Science in 2020. These research results belong to Qin, Yangzhong; Martindale, Benjamin C. M.; Sun, Rui; Rieth, Adam J.; Nocera, Daniel G.. Reference of 1-Bromo-4-(trifluoromethyl)benzene The article mentions the following:

Nickel-catalyzed aryl amination and etherification were driven with sunlight using a surface-modified carbon nitride to extend the absorption of the photocatalyst into a wide range of the visible region. In contrast to traditional homogeneous photochem. methodologies, the lower cost and higher recyclability of the metal-free photocatalyst, along with the use of readily available sunlight, provide an efficient and sustainable approach to promote nickel-catalyzed cross-couplings. In the experimental materials used by the author, we found 1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Reference of 1-Bromo-4-(trifluoromethyl)benzene)

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Some of these compounds are identical to man-made organobromine compounds, such as methyl bromide, bromoform, and bromophenols, but many others are entirely new moleclar entities, often possessing extraordinary and important biological properties. Reference of 1-Bromo-4-(trifluoromethyl)benzene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary