Tag: 200-300

《Selective Hydrogenation of Fatty Nitriles to Primary Fatty Amines: Catalyst Evaluation and Optimization Starting from Octanenitrile》 was written by Hinzmann, Alessa; Groeger, Harald. Application In Synthesis of Bromopentacarbonylmanganese(I) And the article was included in European Journal of Lipid Science and Technology in 2020. The article conveys some information:

In this contribution, an evaluation of the potential of various homogeneous and heterogeneous catalysts for a selective hydrogenation of fatty nitriles toward primary amines is reported exemplified for the conversion of octanenitrile into octane-1-amine as a model reaction. This work describes an optimized hydrogenation process for transforming fatty nitriles to their corresponding primary amines. In general, fatty amines belong to the most applied fatty acid-derived compounds in the chem. industry since such compounds are either directly used in home products such as fabric softeners, dishwashing liquids, car wash detergents, or carpet cleaners or in a broad range of industrial products, for example, lubricating additives, flotation agents, dispersants, emulsifiers, corrosion inhibitors, fungicides, and bactericides, showing addnl. major applications. However, a major concern of current processes is the lack of selectivity and the formation of secondary and tertiary amines as side-products. By modifying a recently developed catalytic system based on manganese as economically attractive and environmentally benign metal component an efficient and selective access to fatty amines when starting from the corresponding nitriles is achieved. For example, hydrogenation of octanenitrile leads to a synthesis of octane-1-amine with >99% conversion and excellent selectivity with formation of secondary and tertiary amine side-products being suppressed to an amount of <1%. In the part of experimental materials, we found many familiar compounds, such as Bromopentacarbonylmanganese(I)(cas: 14516-54-2Application In Synthesis of Bromopentacarbonylmanganese(I))

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Application In Synthesis of Bromopentacarbonylmanganese(I)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Energetic structure-property relationships in thermochemistry of halogenosubstituted benzoic acids》 were Zherikova, Kseniya V.; Verevkin, Sergey P.. And the article was published in Journal of Thermal Analysis and Calorimetry in 2019. Related Products of 76006-33-2 The author mentioned the following in the article:

Exptl. thermodn. properties of halogenosubstituted benzoic acids have been evaluated with the help of complementary in silico methods. The study encompassed benzoic acids with fluoro, chloro-, bromo-, and iodo-substituents in the 2-, 3-, and 4-position in the benzene ring, as well as a series of methyl-substituted bromobenzoic acids and dibromobenzoic acids. The high-level quantum-chem. composite method G4 was addnl. used for mutual validation of the theor. and exptl. gaseous standard molar enthalpies of formation. A simple group contribution procedure has been developed for a quick appraisal of the gas-phase and liquid-phase enthalpies of formation as well as of vaporization enthalpies of halogenosubstituted benzoic acids and their poly-Me or poly-halogen-substituted derivatives The system of group-additivity parameters developed in this work can help in the evaluation of new exptl. results or for validation of already available data compiled in comprehensive databases. Moreover, the reliable additive estimates are essential for material sciences or for assessment of chems. fate in environment and in atm.3-Bromo-2-methylbenzoic acid(cas: 76006-33-2Related Products of 76006-33-2) was used in this study.

3-Bromo-2-methylbenzoic acid(cas: 76006-33-2) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals.Related Products of 76006-33-2 The most pervasive is the naturally produced bromomethane.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Kamio, Shintaro; Kageyuki, Ikuo; Osaka, Itaru; Yoshida, Hiroto. Formula: C7H4BrF3. The article was titled 《Anthranilamide (aam)-substituted arylboranes in direct carbon-carbon bond-forming reactions》. The information in the text is summarized as follows:

Anthranilamide (aam)-substituted arylboranes, which were reported to serve as masked boranes in the Suzuki-Miyaura coupling to afford biaryls Ar-4-MeC6H4 [Ar = 2-furanyl, 4-HOC6H4, 2-methoxypyridinyl, etc.] and R1-R2 [R1 = cyclohexanone; R2 = 4-MeC6H4, 2-methoxypyridinyl] in aqueous medium under microwave conditions. The excellent stability of 2-pyridyl-B(aam) toward protodeborylation allowed their smooth cross-coupling.1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7Formula: C7H4BrF3) was used in this study.

1-Bromo-4-(trifluoromethyl)benzene(cas: 402-43-7) belongs to organobromine compounds.Organobromine chemicals are produced naturally by an array of biological and other chemical processes in our environment. Organobromine compounds are produced naturally by marine creatures (sponges, corals, sea slugs, tunicates, sea fans) and seaweed, plants, fungi, lichen, algae, bacteria, microbes, and some mammals. Formula: C7H4BrF3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2018,Xu, Bingying; Zhou, Haibo; Mei, Qingsong; Tang, Wei; Sun, Yilun; Gao, Mengping; Zhang, Cuilan; Deng, Shengsong; Zhang, Yong published 《Real-Time Visualization of Cysteine Metabolism in Living Cells with Ratiometric Fluorescence Probes》.Analytical Chemistry (Washington, DC, United States) published the findings.Name: 8-Bromooctanoic acid The information in the text is summarized as follows:

Sulfite from cysteine metabolism in living cells plays a crucial role in improving the water solubility of metabolic xenobiotics for their easier excretion in urine or bile. However, an imbalance of sulfite in vivo would lead to oxidative stress or age-related diseases, and an effective strategy for real-time imaging of cysteine metabolism in living cells is still lacking due to its low metabolite concentration and rapid reaction kinetics. Herein, a cyanine moiety based ratiometric fluorescence probe (I) was developed for highly selective and sensitive detection of sulfite in aqueous solution and living cells. The free probe exhibited an orange emission color, and the fluorescence color would gradually change to blue once sulfite anions selectively reacted with the unsaturated carbon double bonds in the probe mol. This ratiometric fluorescence manner endowed the probe excellent sensitivity with a detection limit of 0.78 nM, which was then explored to image the kinetic process of sulfite release in hepatic BRL cells after incubating with an excess amount of cysteine. This strategy opens new opportunities for revealing thiol-containing species metabolism and even quant. tracking their distributions in live cells or organelles. In the experimental materials used by the author, we found 8-Bromooctanoic acid(cas: 17696-11-6Name: 8-Bromooctanoic acid)

8-Bromooctanoic acid(cas: 17696-11-6) acid is used in the synthesis of 8-(N-Methyl-4,4′-bipyridinyl)- octanoic acid. 8-Mercaptooctanoic acid was prepared from 8-bromooctanoic acid.Name: 8-Bromooctanoic acid

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Name: Methyl 3-(bromomethyl)benzoateIn 2018 ,《A highly potent and selective inhibitor Roxyl-WL targeting IDO1 promotes immune response against melanoma》 was published in Journal of Enzyme Inhibition and Medicinal Chemistry. The article was written by Xu, Guangwei; Wang, Tianqi; Li, Yongtao; Huang, Zhi; Wang, Xin; Zheng, Jianyu; Yang, Shengyong; Fan, Yan; Xiang, Rong. The article contains the following contents:

Indoleamine 2,3-dioxygenase 1 (IDO1) activity links to immune escape of cancers. Inhibition of IDO1 provides a new approach for cancer treatment. Most clin. IDO1 drugs show marginal efficacy as single agents. On basis of mol. docking and pharmacophore modeling, a novel inhibitor Roxyl-WL was discovered with a half maximal inhibitory concentration (IC50) value of 1 nM against IDO1 and 10-100-fold increased potent activity compared with IDO1 drugs in clin. trials. Roxyl-WL displayed excellent kinase spectrum selectivity with no activity out of the 337 protein kinases. In vitro, Roxyl-WL effectively augmented the proliferation of T cells and reduced the number of regulatory T cell (Tregs). When administered to melanoma (B16F10) tumor-bearing mice orally, Roxyl-WL significantly suppressed tumor growth and induced immune response. The experimental process involved the reaction of Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Name: Methyl 3-(bromomethyl)benzoate)

Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.Name: Methyl 3-(bromomethyl)benzoate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Wu, Qianqian; Li, Minghong; He, Shuanglin; Xiong, Ying; Zhang, Ping; Huang, Heyan; Chen, Lin; Huang, Fang; Li, Fei published an article in Chemical Communications (Cambridge, United Kingdom). The title of the article was 《Hangman effect boosts hydrogen production by manganese terpyridine complex》.Recommanded Product: Bromopentacarbonylmanganese(I) The author mentioned the following in the article:

The manganese terpyridine complex 1 with a coordinated carboxylate in the axial position was obtained in situ. By virtue of a hangman effect, complex 1 catalyzes electrochem. hydrogen evolution from phenol in acetonitrile solution with a turnover frequency of 525 s-1 at a low overpotential of ca. 230 mV. After reading the article, we found that the author used Bromopentacarbonylmanganese(I)(cas: 14516-54-2Recommanded Product: Bromopentacarbonylmanganese(I))

Bromopentacarbonylmanganese(I)(cas: 14516-54-2) has many other uses. It is used in the formation of (eta6-arene)tricarbonylmanganese(I) by reacting with arene (arene= hexamethyl benzene, 1,2,4,5-tetramethyl benzene, mesitylene, p-xylene and toluene) in the presence silver salt.Recommanded Product: Bromopentacarbonylmanganese(I)

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hess, Andreas; Alandini, Nurtalya; Guelen, Hasret C.; Prohaska, Jan P.; Knochel, Paul published an article in 2022. The article was titled 《Regioselective magnesiations of functionalized arenes and heteroarenes using TMP2Mg in hydrocarbons》, and you may find the article in Chemical Communications (Cambridge, United Kingdom).Electric Literature of C7H5BrO2 The information in the text is summarized as follows:

The preparation of a new hydrocarbon-soluble magnesium amide TMP2Mg (TMP = 2,2,6,6-tetramethylpiperidyl) was report . This base showed excellent properties for the regioselective magnesiation of various arenes and heteroarenes bearing Et esters and carbamates under very mild reaction conditions. Subsequent trapping with aryl iodides (Negishi cross-coupling) gave access to a range of highly functionalized valuable building blocks such as I [R = 2-F,6-C(O)OEt, 2-F,6-C(O)Ot-Bu, 2-C(O)OEt, etc. R1 = I, 2-thienyl, 3-MeOC6H4, etc.]. The results came from multiple reactions, including the reaction of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4Electric Literature of C7H5BrO2)

Furthermore, the coupling of 5-Bromobenzo[d][1,3]dioxole(cas: 2635-13-4) with β-methallyl alcohol was catalyzed by Pd(OAc)2 in combination with P(t-Bu)3.Electric Literature of C7H5BrO2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Hu, Qing-Hua; Jiang, Wei; Liang, Ru-Ping; Lin, Sen; Qiu, Jian-Ding published an article in 2021. The article was titled 《Synthesis of imidazolium-based cationic organic polymer for highly efficient and selective removal of ReO-4/TcO-4》, and you may find the article in Chemical Engineering Journal (Amsterdam, Netherlands).HPLC of Formula: 623-24-5 The information in the text is summarized as follows:

Rational design of anion-scavenging materials with high selectivity and stability under high acid/base extreme conditions for removing 99TcO4- is still a significant challenge. Herein, we put forward an anion exchange strategy that utilized an imidazolium-based cationic organic polymer (named ImCOP) for efficient capture of perrhenate (ReO4-), a surrogate for TcO4- with nonradioactive. ImCOP was synthesized via the quaternization reaction using tris (4-(1H-imidazol-1-yl) phenyl) amine, a tripodal flexible ligand, and 1,4-bis (bromomethyl) benzene to forming a semi-rigid structure. ImCOP exhibited high chem. stability even under 3 M HNO3 and 3 M NaOH, which was superior to those of most materials. Attributed to the charged imidazolium moieties and tertiary amine groups that produced rich adsorption sites, ImCOP can produce electrostatic interactions with ReO4-, thereby leading to a record uptake capability (1162 mg g-1) of ReO4-. Furthermore, ImCOP exhibited high selectivity for removing ReO4- in the presence of large excess of competitive anions, which was attributed to the hydrophobic surface of ImCOP. These excellent features endowed ImCOP successfully separated ReO4- from simulated Hanford waste with a high adsorption removal of 93.4%. The excellent performance suggested ImCOP would be a promising material for TcO4-/ReO4-removal, which provided a feasible pathway for designing a high-efficiency and durable material for nuclear-related environmental remediation. The results came from multiple reactions, including the reaction of 1,4-Bis(bromomethyl)benzene(cas: 623-24-5HPLC of Formula: 623-24-5)

1,4-Bis(bromomethyl)benzene(cas: 623-24-5) belongs to organobromine compounds.The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. HPLC of Formula: 623-24-5 Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3,5-DibromoanilineIn 2020 ,《Structurally Informative Isotopic Shifts in Ion Mobility Spectra for Heavier Species》 was published in Journal of the American Society for Mass Spectrometry. The article was written by Pathak, Pratima; Baird, Matthew A.; Shvartsburg, Alexandre A.. The article contains the following contents:

The isotopic mol. envelopes due to stable isotopes for most elements were a staple of mass spectrometry since its origins, often leveraged to identify and quantify compounds However, all isomers share one MS envelope. As the mol. motion in media also depends on the isotopic composition, separations such as liquid chromatog. (LC) and ion mobility spectrometry (IMS) must also feature isotopic envelopes. These were largely not observed because of limited resolution, except for the (structurally uninformative) shifts in LC upon H/D exchange. We recently found the isotopic shifts in FAIMS for small haloanilines (∼130-170 Da) to hinge on the halogen position, opening a novel route to isomer characterization. Here, we extend the capability to heavier species: dibromoanilines (DBAs, ∼250 Da) and tribromoanilines (TBAs, ∼330 Da). The 13C shifts for DBAs and TBAs vary across isomers, some changing sign. While 81Br shifts are less specific, the 2-D 13C/81Br shifts unequivocally differentiate all isomers. The trends for DBAs track those for dichloroanilines, with the 13C shift order preserved for most isomers. The peak broadening due to merged isotopomers is also isomer-specific. The absolute shifts for TBAs are smaller than those for lighter haloanilines, but differentiate isomers as well because of compressed uncertainties. These results showcase the feasibility of broadly distinguishing isomers in the more topical ∼200-300 Da range using the isotopic shifts in IMS spectra. In the experimental materials used by the author, we found 3,5-Dibromoaniline(cas: 626-40-4Recommanded Product: 3,5-Dibromoaniline)

3,5-Dibromoaniline(cas: 626-40-4) belongs to anime. In organic chemistry, amines are compounds and functional groups that contain a basic nitrogen atom with a lone pair. Amines are formally derivatives of ammonia (NH3), wherein one or more hydrogen atoms have been replaced by a substituent such as an alkyl or aryl group (these may respectively be called alkylamines and arylamines; amines in which both types of substituent are attached to one nitrogen atom may be called alkylarylamines).Recommanded Product: 3,5-Dibromoaniline

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2018,Cui, Yuxiao; Zhao, Wenjie; Ogasawara, Shin; Wang, Xiao-Feng; Tamiaki, Hitoshi published 《Fabrication and performance of all-solid-state dye-sensitized solar cells using synthetic carboxylated and pyridylated chlorophyll derivatives》.Journal of Photochemistry and Photobiology, A: Chemistry published the findings.Name: Methyl 3-(bromomethyl)benzoate The information in the text is summarized as follows:

All-solid-state dye-sensitized solar cells (DSSCs) based on a mesoporous TiO2 electrode were fabricated using synthetic chlorophyll derivatives as a photosensitizer and 2,2′,7,7′-tetrakis[N,N-di(4-methoxyphenyl)amino]-9,9′-spirobifluorene as a hole-transport material. Me pyropheophorbides-a possessing a carboxy group in the C3-substituent as the anchoring moiety to the TiO2 surface were effective DSSCs. Direct conjugation of the COOH group with the terminus of the C3-vinyl group gave the highest solar energy-to-electricity conversion efficiency (η) of 2.25%. Insertion of a 1,3-phenylene group in the connection partially suppressed the efficiency by 25% (η = 1.68%), whereas insertion of an isomeric 1,4-phenylene moiety decreased to one third (0.75%). A pyridyl group was not useful as the sensitizer anchor due to its low binding affinity to the TiO2 electrode. In the experiment, the researchers used Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8Name: Methyl 3-(bromomethyl)benzoate)

Methyl 3-(bromomethyl)benzoate(cas: 1129-28-8) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Name: Methyl 3-(bromomethyl)benzoate Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary