Tag: 300-400

Variations on the Blaise Reaction: Synthesis of 3,5-Dioxopentanoates and 3-Amino-5-oxopent-3-enoates was written by Rao, H. Surya Prakash;Muthanna, Nandurka. And the article was included in Synlett in 2016.SDS of cas: 80480-15-5 The following contents are mentioned in the article:

A facile and convenient synthesis of a variety of 3,5-dioxopentanoates (3,5-diketo esters) and 3-amino-5-oxopent-3-enoates by a zinc-mediated condensation of readily available 3-oxopropanenitriles (α-cyano ketones) with Et bromoacetate was described. The reaction is a variation on the classical Blaise reaction, tuned to the synthesis of trifunctional compounds having 3,5-diketo ester or 3-enamino 5-keto ester functional groups. This study revealed that the Blaise reaction on the nitrile occurs in preference to the Reformatsky reaction on the neighboring ketone when the two functional groups are in a geminal relationship, as found in α-cyano ketones, possibly due to zinc complexation leading to increased electrophilicity of the nitrile. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5SDS of cas: 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. SDS of cas: 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Variations in the Blaise Reaction: Conceptually New Synthesis of 3-Amino Enones and 1,3-Diketones was written by Rao, H. Surya Prakash;Muthanna, Nandurka. And the article was included in European Journal of Organic Chemistry in 2015.Related Products of 80480-15-5 The following contents are mentioned in the article:

The synthesis of 3-amino enones and 1,3-diketones starting from aryl/heteroaryl/alkyl nitriles and 1-aryl/alkyl 2-bromoethanones. The reaction is a variation of the classical Blaise reaction, and it works with zinc and trimethylsilyl chloride as an activator. By running the hydrolysis of the reaction intermediate with HCl (3N aqueous) at 0-30° or at 100°, it is possible to form either 3-amino enones or 1,3-diketones, resp. The newly developed method was used for the synthesis of avobenzone, an ingredient of sun-screen lotions. Furthermore, an easy synthesis of (Z)-3-amino-1-[4-(tert-butyl)phenyl]-3-(4-methoxyphenyl)prop-2-en-1-one, with UV/Vis absorption characteristics similar to those of avobenzone, was also achieved. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Related Products of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Related Products of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Simultaneous determination of salinomycin and monensin in chicken meat by HPLC was written by Miyakawa, Hiroyuki;Horii, Shozo;Kokubo, Yataro. And the article was included in Shokuhin Eiseigaku Zasshi in 1995.Name: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

A method for simultaneous determination of salinomycin and monensin in chicken meat by HPLC with a fluorescence detector was developed. Salinomycin and monensin were extracted with MeCN from a meat sample. The extract was partitioned between Et acetate and water, and the Et acetate layer was cleaned up with a Sep-pak Silica cartridge. Salinomycin and monensin were reacted with 1-bromoacetylpyrene to form fluorescent derivatives After clean-up with a Sep-pak Florisil cartridge, the derivatives were determined by HPLC with a fluorescence detector. The recoveries of salinomycin and monensin from chicken meat spiked at the levels of 0.1 ppm and 1 ppm were 66.2-96.2%. The detection limits were 0.05 ppm for the 2 antibiotics. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Name: 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Name: 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis of non-peripherally and peripherally substituted zinc (II) phthalocyanines bearing pyrene groups via different routes and their photophysical properties was written by Surgun, Serdar;Arslanoglu, Yasin;Hamuryudan, Esin. And the article was included in Dyes and Pigments in 2014.Safety of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

This work reports on photophys. properties of the non-peripherally and peripherally substituted Zn phthalocyanines (Pcs) prepared by two different synthetic routes. Tetra-substituted non-peripheral and peripheral Zn phthalocyanines containing 4-mercaptophenol groups were synthesized from novel phthalonitrile derivatives for the 1st time. Pyrene-containing phthalocyanine derivatives were obtained by the reaction of these compounds with 1-bromoacetylpyrene. In the 2nd route, the pyrene-containing phthalocyanine derivatives were prepared by cyclotetramerization of pyrene-containing phthalonitrile derivatives The synthesized compounds were characterized by elemental anal., FTIR, UV-visible, NMR spectroscopy and mass spectra. General trends were described for electronic absorption, fluorescence quantum yields, lifetimes, and fluorescence quenching by benzoquinone of these compounds The effects of position of substituent on photophys. properties of the tetra-substituted Zn Pcs were also studied. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Safety of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Safety of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Rebuilding ring-type assembly of peroxiredoxin by chemical modification was written by Himiyama, Tomoki;Tsuchiya, Yuko;Yonezawa, Yasushige;Nakamura, Tsutomu. And the article was included in Bioconjugate Chemistry in 2021.Category: bromides-buliding-blocks The following contents are mentioned in the article:

Direct control of the protein quaternary structure (QS) is challenging owing to the complexity of the protein structure. As a protein with a characteristic QS, peroxiredoxin from Aeropyrum pernix K1 (ApPrx) forms a decamer, wherein five dimers associate to form a ring. Here, we disrupted and reconstituted ApPrx QS via amino acid mutations and chem. modifications targeting hot spots for protein assembly. The decameric QS of an ApPrx* mutant, wherein all cysteine residues in wild-type ApPrx were mutated to serine, was destructed to dimers via an F80C mutation. The dimeric ApPrx*F80C mutant was then modified with a small mol. and successfully assembled as a decamer. Structural anal. confirmed that an artificially installed chem. moiety potentially facilitates suitable protein-protein interactions to rebuild a native structure. Rebuilding of dodecamer was also achieved through an addnl. amino acid mutation. This study describes a facile method to regulate the protein assembly state. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Category: bromides-buliding-blocks).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. Bromine-containing agents predominate because not only are they more efficient than similar chlorine-containing species, but also the high atomic weight of bromine ensures that it is present in a high mass fraction within most organobromine compounds.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Detection of okadaic acid by high-performance liquid chromatography in mussels (Perna perna) captured in the Sepetiba Bay was written by Oliveira, G. M.;Silva, P. P. O.;Rosa, C. A. R.;Bastos, R. A.;Ferreira, V. M.;Rodrigues, E. S.. And the article was included in Alimentaria (Madrid, Spain) in 2005.Formula: C18H11BrO The following contents are mentioned in the article:

Okadaic acid (OA) is one of the main toxins responsible for diarrhea from shellfish poisoning (DSP) in humans. The OA was extracted from hepatopancreas of mussels (Perna perna) collected on the Sepetiba and Mangaratiba beaches in Rio de Janeiro (Brazil), derivatized with 1-(bromoacetyl)pyrene, and analyzed by HPLC with fluorescence detection (HPLC-FLD). The retention time of the AO standard was 18.041 min at 11.27 ng/g and 18.318 min at 26.81 ng/g in samples spiked with equivalent of 20 ng OA/g hepatopancreas tissue. The method allowed better evaluation of the presence of AO in non-spiked extracts The OA retention time for the non-spiked extracts was 17.788 min at 26.55 ng/g in samples from the Sepetiba beach and 18.068 min at 10.14 ng/g in samples from the Mangaratiba beach. The detection limit for OA was 8.1 ng/g hepatopancreas tissue at signal:noise ratio of 3:1. The data indicate the presence of OA in the Perna perna mussels from the Sepetiba and Mangaratiba beaches. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Low-cost and efficient hole transport materials based on 9-phenyl-9H-carbazole branch for perovskite solar cells was written by Wu, Yehui;Gong, Zhiming;Jiang, Yue;Wang, Ru;Xu, Dongdong;Xu, Zhengjie;Zhou, Guofu;Liu, Jun-Ming;Gao, Jinwei. And the article was included in Surfaces and Interfaces in 2022.Quality Control of 3-Bromo-9-(4-fluorophenyl)-9H-carbazole The following contents are mentioned in the article:

Hole transport materials (HTMs) play a pivotal role in the hole extraction and transportation processes in perovskite solar cells (PSCs). Although a great number of HTMs based on various planar conjugated cores have been explored, the development of branches is rather limited. In this work, branches of 9-phenyl-9H-carbazole derivatives have been incorporated in different N-alkylated dithieno[3,2-b:2′,3′-d]pyrrol (DTP) core to construct HTMs (TM-9 to TM-14). Among them, TM-13 with 9-(4-methoxyphenyl)-9H-carbazole branch exhibites excellent performance in hole extraction and transportation ability. Consequently, the PSCs based on TM-13 have achieved the power conversion efficiency (PCE) of 20.44%, which is comparable to the PCE of 20.62% with the widely used Spiro-OMeTAD HTM. More importantly, the synthetic cost of TM-13 (62 dollar/g) is much lower than that of Spiro-OMeTAD (400 dollar/g), suggesting its promising commercialization for low-cost and efficient HTMs for PSCs. This study involved multiple reactions and reactants, such as 3-Bromo-9-(4-fluorophenyl)-9H-carbazole (cas: 922721-30-0Quality Control of 3-Bromo-9-(4-fluorophenyl)-9H-carbazole).

3-Bromo-9-(4-fluorophenyl)-9H-carbazole (cas: 922721-30-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Quality Control of 3-Bromo-9-(4-fluorophenyl)-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Tuneable enhancement of the salt and thermal stability of polymeric micelles by cyclized amphiphiles was written by Honda, Satoshi;Yamamoto, Takuya;Tezuka, Yasuyuki. And the article was included in Nature Communications in 2013.COA of Formula: C18H11BrO The following contents are mentioned in the article:

Cyclic mols. provide better stability for their aggregates. Typically in nature, the unique cyclic cell membrane lipids allow thermophilic archaea to inhabit extreme conditions. By mimicking the biol. design, the robustness of self-assembled synthetic nanostructures is expected to be improved. Here we report topol. effects by cyclized polymeric amphiphiles against their linear counterparts, demonstrating a drastic enhancement in the thermal, as well as salt stability of self-assembled micelles. Furthermore, through coassembly of the linear and cyclic amphiphiles, the stability was successfully tuned for a wide range of temperatures and salt concentrations The enhanced thermal/salt stability was exploited in a halogen exchange reaction to stimulate the catalytic activity. The mechanism for the enhancement was also investigated. These topol. effects by the cyclic amphiphiles offer unprecedented opportunities in polymer materials design unattainable by traditional means. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5COA of Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.COA of Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Helical Superstructures of Fullerene Peapods and Empty Single-Walled Carbon Nanotubes Formed in Water was written by Nakashima, Naotoshi;Tanaka, Yasuhiko;Tomonari, Yasuhiko;Murakami, Hiroto;Kataura, Hiromichi;Sakaue, Takahiro;Yoshikawa, Kenichi. And the article was included in Journal of Physical Chemistry B in 2005.Application of 80480-15-5 The following contents are mentioned in the article:

Aqueous dispersions of fullerene C₇₀-filled carbon nanotubes (C₇₀@SWNTs or peapods) and empty single-walled carbon nanotubes (empty SWNTs) were prepared with the aid of trimethyl-(2-oxo-2-pyrene-1-yl-ethyl)-ammonium bromide (1), which is a carbon nanotube solubilizer. This is the first report describing the preparation and characterization of the transparent dispersion/dissolution of the peapods. The UV-vis-near-IR spectra of C₇₀@SWNTs-1 and empty SWNTs-1 were almost identical. We found by means of transmission electron microscopy and at. force microscopy that the empty SWNTs and C₇₀-peapods form helical nanostructures in the shapes of rings, irregular rings, lassos, handcuffs, catenanes, pseudorotaxanes, and figure-eight structures. The mechanism of the superstructure formation has been discussed in relation to the unique characteristics of stiff polymer chains with the aid of an off-lattice Monte Carlo simulation. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Application of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Pyrene-based ratiometric and fluorescent sensor for selective Al³⁺ detection was written by Liang, Jing;Liu, Hai-Bo;Wang, Jing. And the article was included in Inorganica Chimica Acta in 2019.Safety of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

A pyrene-based sensor, named DBT (I), was synthesized through a one-step reaction and used as a ratiometric and fluorescent sensor for recognizing Al³⁺. The sensor showed high selectivity and sensitivity toward Al³⁺ relative to other competitive metal ions. DBT exhibited very weak fluorescence because of the photo-induced electron transfer process (PET). In the presence of Al³⁺, the emission of DBT at 451 nm enhanced owing to the coordination between DBT and Al³⁺ which hindered the PET. The detection of Al³⁺ by DBT was realized in a wide pH range of 5-12. The detection limits of Al³⁺ were 0.19 and 0.10 μM by ratiometric absorption (A_360 nm/A_342 nm) and fluorescent (F_451 nm) methods, resp. Moreover, DBT was also successfully applied to detect Al³⁺ in practical water samples and solid phase (TLC plate). This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Safety of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Safety of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary