Tag: 300-400

Indolizine-Squaraines: NIR Fluorescent Materials with Molecularly Engineered Stokes Shifts was written by McNamara, Louis E.;Rill, Tana A.;Huckaba, Aron J.;Ganeshraj, Vigneshraja;Gayton, Jacqueline;Nelson, Rachael A.;Sharpe, Emily Anne;Dass, Amala;Hammer, Nathan I.;Delcamp, Jared H.. And the article was included in Chemistry – A European Journal in 2017.SDS of cas: 80480-15-5 The following contents are mentioned in the article:

The development of deep red and near IR emissive materials with high quantum yields is an important challenge. Several classes of squaraine dyes have demonstrated high quantum yields, but require significantly red-shifted absorptions to access the NIR window. Addnl., squaraine dyes have typically shown narrow Stokes shifts, which limits their use in living biol. imaging applications due to dye emission interference with the light source. Through the incorporation of indolizine heterocycles we have synthesized novel indolizine squaraine dyes with increased Stokes shifts (up to >0.119 eV, >50 nm increase) and absorptions substantially further into the NIR region than an indoline squaraine benchmark (726 nm vs. 659 nm absorption maxima). These materials have shown significantly enhanced water solubility, which is unique for squaraine dyes without water-solubilizing substituents. Absorption, electrochem., computational, and fluorescence studies were undertaken and exceptional fluorescence quantum yields of up 12 % were observed with emission curves extending beyond 850 nm. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5SDS of cas: 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.SDS of cas: 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis, Antimicrobial Activity and Molecular Docking Studies of 1,3-Thiazole Derivatives Incorporating Adamantanyl Moiety was written by Laczkowski, K. Z.;Misiura, K.;Biernasiuk, A.;Malm, A.;Paneth, A.;Plech, T.. And the article was included in Journal of Heterocyclic Chemistry in 2016.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

Synthesis, characterization and study of antimicrobial activity of 11 novel adamantanyl-thiazoles are presented. Their structures were determined using ¹H and ¹³C NMR, EI(+)-MS, HRMS, and elemental analyses. Among the derivatives, compound showed very strong activity, especially against Candida albicans ATCC 10231 and Candida parapsilosis ATCC 22019 with minimal inhibitory concentration (MIC) values ranging from 1.95 to 7.81 μg/mL. Compounds and showed good antifungal activity. Among the examined compounds, the widest spectrum of antibacterial activity possessed that showed good activity, especially against Staphylococcus epidermidis ATCC 12228, Micrococcus luteus ATCC 10240, Bacillus subtilis ATCC 6633 with MIC values ranging from 31.25 to 62.5 μg/mL. Mol. docking studies of all compounds on the active sites of microbial enzymes indicated possible targets sterol 14α-demethylase, secreted aspartic proteinase (SAP), N-myristoyltransferase (NMT), and topoisomerase II. Thiazoles showed more favorable affinity to SAP and NMT than the native ligand. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. Commercially available organobromine pharmaceuticals include the vasodilator nicergoline, the sedative brotizolam, the anticancer agent pipobroman, and the antiseptic merbromin. Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Copolymerization of n-butyl acrylate with styrene by a novel photoinitiator, 1-(bromoacetyl)pyrene was written by Mishra, Anuradha;Daswal, Swati. And the article was included in Journal of Applied Polymer Science in 2006.Application In Synthesis of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

A comparative study on photoinitiated solution copolymerization of Bu acrylate (BA) with styrene (Sty) using pyrene (Py), 1-acetylpyrene (AP), and 1-(bromoacetyl)pyrene (BP) as initiators showed that the introduction of a chromophoric moiety, bromoacetyl (-COCH₂Br), significantly increased the photoinitiating ability of pyrene. The kinetics and mechanism of copolymerization of BA with Sty using BP as photoinitiator have been studied in detail. The system follows nonideal kinetics (R_p ∝ [BP]^0.34 [BA]^1.07 [Sty]^0.97). The nonideality was attributed to both primary radical termination and degradative initiator transfer. The monomer reactivity ratios of Sty and BA have been estimated by the Finemann-Ross and Kelen-Tudos methods, by analyzing copolymer compositions determined by ¹H NMR spectra. The values of r₁ (Sty) and r₂ (BA) were found to be 0.78 and 0.25, resp., which suggested the high concentration of alternating sequences in the random copolymers obtained. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application In Synthesis of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Application In Synthesis of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis and properties of amphipathic fluorescent dye derived from spiculisporic acid anhydride was written by Ishigami, Yutaka;Gama, Yasuo;Matsuzaki, Sanae. And the article was included in Shikizai Kyokaishi in 1991.Formula: C18H11BrO The following contents are mentioned in the article:

The 1-pyrenecarbonylmethyl ester (I) of spiculisporic acid anhydride was synthesized as an amphipathic fluorescent probe from a microbial biosurfactant. I was synthesized by the reaction of spiculisporic acid anhydride, which was derived from spiculisporic acid, with 1-(bromoacetyl)pyrene. I showed different fluorescent spectra by behaving as “fingerprints” in response to various kinds of hydrophobic environments of solvents, mol. aggregates, and liposomes. I gave different fluorescent patterns in solvents depending on the solubility parameter. Excimer formation of I was accelerated in larger micellar domains of heptaoxyethylene dodecyl ether than in SDS. The dependence of the spectrum on surfactant concentrations was also notable. I was considered to have a larger membrane fluidity in liposomal bilayers than in micelles from the different emitting wavelengths of the resp. excimers in liposomes (511 nm) and micelles (440 or 453 nm). This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Site-Selective N-Arylation of Carbazoles with Halogenated Fluorobenzenes was written by Wang, Lei;Ji, Enhui;Liu, Ning;Dai, Bin. And the article was included in Synthesis in 2016.Synthetic Route of C18H11BrFN The following contents are mentioned in the article:

A method for the highly site-selective C-N bond-formation reaction of halogenated fluorobenzenes with carbazoles was described. The selectivity of iodine and fluorine atoms on the aromatic ring of fluorinated iodobenzenes was initially determined with a copper-N,N-diisopropylethylamine catalytic system. By changing the position of the iodine atom on the aromatic ring from the 3- or 4-position to the 2-position, the preferred coupling site was switched from the iodine atom to the fluorine atom. Steric hindrance of the fluorinated iodobenzenes was responsible for the selectivity switch. After elucidating the reaction mechanisms of these reaction processes, a metal-free method for the highly site-selective C-N bond-formation reaction of halogenated fluorobenzenes with carbazoles was revealed through C-F bond activation. The metal-free system was able to handle a range of halogenated groups. Thus, a broad range of chlorinated, brominated, and iodinated N-arylated carbazoles were generated, which are widely useful in organic chem. This study involved multiple reactions and reactants, such as 3-Bromo-9-(4-fluorophenyl)-9H-carbazole (cas: 922721-30-0Synthetic Route of C18H11BrFN).

3-Bromo-9-(4-fluorophenyl)-9H-carbazole (cas: 922721-30-0) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Synthetic Route of C18H11BrFN

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Improvement on sample clean-up for high-performance liquid chromatographic-fluorimetric determination of diarrhetic shellfish toxins using 1-bromoacetylpyrene was written by Gonzalez, Jose C.;Vieytes, Mercedes R.;Vieites, Juan M.;Botana, Luis M.. And the article was included in Journal of Chromatography A in 1998.Electric Literature of C18H11BrO The following contents are mentioned in the article:

Okadaic acid (OA) and dinophysistoxin-2, two of the main diarrhetic shellfish toxins, can be determined by high-performance liquid chromatog. coupled to fluorimetry as pyrenacyl esters. Toxin fluorescent derivatives were obtained after quant. derivatization with 1-bromoacetylpyrene in acetonitrile. An efficient improvement in the silica gel clean-up procedure of the pyrenacyl derivatives is reported. The clean-up cartridge is washed with hexane-dichloromethane (1:1, volume/volume), dichloromethane-Et acetate (8:2, volume/volume), and finally the pyrenacyl esters were eluted with dichloromethane-methanol (9:1, volume/volume). The authors compare this procedure with other methods already described. Good results were obtained with mussels, scallops and clams. The clean-up procedure showed good robustness when checked against silica and solvents activity. Using samples of mussel hepatopancreas with an OA concentration ranging from 0 to 2 μg OA/g hepatopancreas, the inter-assay relative standard deviation ranged from 5.5 to 12.6. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Electric Literature of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Electric Literature of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Quantification of lipopeptides using high-performance liquid chromatography with fluorescence detection after derivation was written by Meng, Yong;Liu, Jin-Feng;Yang, Shi-Zhong;Ye, Ru-Qiang;Mu, Bo-Zhong. And the article was included in Analytical Sciences in 2015.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

A highly sensitive and selective high-performance liquid chromatog. (HPLC) method has been developed for the determination of microbial lipopeptides of fluorescent derivatization with 1-bromoacetylpyrene to overcome the limitations of trace detection of lipopeptides in aqueous solutions The derivatization of lipopeptides with 1-bromoacetylpyrene was conducted at 60°C for 20 min under catalysis of triethylarnine. The resulting derivative products were separated by HPLC and determined by a fluorescence detector. Each homolog of lipopeptides in samples was identified by HPLC-MS and the detection limit after derivatization in an aqueous solution was 2.5 μg/mL (S/N = 3), The calibration curve for lipopeptides was linear in the concentration range of 0.250 – 4.00 mg/mL. This method has adequate sensitivity and selectivity for microdetection of lipopeptides in aqueous solutions in mild reaction conditions, which allows this method to be used in the determination of trace lipopeptides in environmental samples and complex samples. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

1-Acetylpyrene-Salicylic Acid: Photoresponsive Fluorescent Organic Nanoparticles for the Regulated Release of a Natural Antimicrobial Compound, Salicylic Acid was written by Barman, Shrabani;Mukhopadhyay, Sourav K.;Behara, Krishna Kalyani;Dey, Satyahari;Singh, N. D. Pradeep. And the article was included in ACS Applied Materials & Interfaces in 2014.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

Photoresponsive 1-acetylpyrene-salicylic acid (AcPy-SA) nanoparticles (NPs) were developed for the regulated release of a natural antimicrobial compound, salicylic acid. The strong fluorescent properties of AcPy-SA NPs have been extensively used for potential in vitro cell imaging. The phototrigger capability of our newly prepared AcPy-SA NPs was utilized for the efficient release of an antimicrobial compound, salicylic acid. The photoregulated drug release of AcPy-SA NPs has been shown by the subsequent switching off and on of a visible-light source. In vitro biol. studies reveal that AcPy-SA NPs of ∼68 nm size deliver the antimicrobial drug salicylic acid into the bacteria cells (Pseudomonas aeruginosa) and efficiently kill the cells upon exposure to visible light (≥410 nm). Such photoresponsive fluorescent organic NPs will be highly beneficial for targeted and regulated antimicrobial drug release because of their biocompatible nature, efficient cellular uptake, and light-induced drug release ability. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A pyrene thiazole conjugate as a ratiometric chemosensor with high selectivity and sensitivity for tin (Sn⁴⁺) and its application in imaging live cells was written by Mahapatra, Ajit Kumar;Mondal, Sanchita;Maiti, Kalipada;Manna, Saikat Kumar;Maji, Rajkishor;Mandal, Debasish;Mandal, Sukhendu;Goswami, Shyamaprosad;Quah, Ching Kheng;Fun, Hoong-Kun. And the article was included in RSC Advances in 2014.Related Products of 80480-15-5 The following contents are mentioned in the article:

A new pyrene thiazole conjugate (PTC) amine fluoroionophore was synthesized and characterized. The single crystal XRD structure of PTC has been established. The fluoroionophore PTC showed selectivity toward Sn⁴⁺ by switching on ratiometric fluorescence among the 16 metal ions studied in HEPES buffer medium with a detection limit of 6.93μM. The interaction of Sn⁴⁺ with PTC has been further supported by absorption studies, and the stoichiometry of the complex formed (2:1) has been established on the basis of fluorescence and ESI-MS. Competitive ion titrations carried out reveal that the Sn⁴⁺ can be detected even in the presence of other metal ions of bio-importance. Moreover, the utility of the fluoroionophore PTC in showing the tin recognition in live cells has also been demonstrated using Vero 76 cells as monitored by fluorescence imaging. The tin complex of PTC was isolated, and the structure and electronic properties of [PTC-Sn] has been established by DFT and TDDFT calculations The isolated tin complex [PTC-Sn] has been used as a mol. tool for the recognition of anions on the basis of their binding affinities toward Sn⁴⁺. [PTC-Sn] is sensitive and selective toward sulfide ions among the other 12 anions studied. The selectivity has been shown on the basis of the changes observed in the emission and absorption spectral studies through the removal of Sn⁴⁺ from [PTC-Sn] by S^2-. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Related Products of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Related Products of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Enhancing the reinforcing efficiency in CNT nanocomposites via the development of pyrene-based active dispersants was written by Yin, Xinyi;Li, Qiang;Wang, Haishui;Yang, Wengang;Zhou, Xi;Zhang, Han;Lyu, Weibang. And the article was included in RSC Advances in 2021.Quality Control of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Various preforms of carbon nanotubes (CNTs), such as fibers, yarns, or buckypapers (BP), have been developed over the last few years in order to fabricate advanced nanocomposites containing a high volume fraction of the reinforcing phase. However, a homogeneous dispersion and an even isolation of CNTs during the fabrication process of many preforms such as BP is often challenging, while the poor interaction between CNTs and the matrix also limits the final performance of the nanocomposites. Herein, a new route to overcome these two challenges simultaneously has been demonstrated based on an active dispersant (noted as Py-PEI) developed through the quaternization reaction of pyrene derivatives (Py-Br) and polyethylenimine (PEI). The existence of pyrene groups leads to the formation of π-π stacking with CNTs, successfully hindering the re-aggregation of dispersed CNTs. Meanwhile, the amine groups of Py-PEI can establish covalent bonds with epoxy, leading to an enhanced load transfer efficiency between CNTs and epoxy in the composites. Systematic characterization of both fabricated BP and BP-reinforced nanocomposites have been performed, with significantly enhanced CNT dispersion stability in water together with improved mech. performance of the as-obtained BP/epoxy nanocomposites. This study provides a new strategy in fabricating high performance nanocomposites with the ease of nanofiller dispersion and enhanced reinforcing efficiency. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Quality Control of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Quality Control of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary