Tag: 300-400

Soft Ultraviolet (UV) Photopatterning and Metallization of Self-Assembled Monolayers (SAMs) Formed from the Lipoic Acid Ester of α-Hydroxy-1-acetylpyrene: The Generality of Acid-Catalyzed Removal of Thiol-on-Gold SAMs using Soft UV Light was written by Pukenas, Laurynas;Prompinit, Panida;Nishitha, Boda;Tate, Daniel J.;Singh, N. D. Pradeep;Walti, Christoph;Evans, Stephen D.;Bushby, Richard J.. And the article was included in ACS Applied Materials & Interfaces in 2017.Related Products of 80480-15-5 The following contents are mentioned in the article:

Under a layer of 0.1 M HCl in isopropanol, soft UV (365 nm) photolysis of the thiol-on-gold self-assembled monolayer (SAM) derived from the lipoic acid ester of α-hydroxy-1-acetylpyrene results in the expected removal of the acetylpyrene protecting group. When photolyzing through a mask, this can be used to produce a patterned surface and, at a controlled electrochem. potential, it is then possible to selectively and reversibly electrodeposit copper on the photolyzed regions. Rather surprisingly, under these photolysis conditions, there is not only the expected photodeprotection of the ester but also partial removal of the lipoic acid layer which has been formed. In further studies, it is shown that this type of acid-catalyzed photoremoval of SAM layers by soft UV is a rather general phenomenon and results in the partial removal of the thiol-on-gold SAM layers derived from other ω-thiolated carboxylic acids. However, this phenomenon is chain-length dependent. Under conditions in which there is a ∼60% reduction in the thickness of the SAM derived from dithiobutyric acid, the SAM derived from mercaptoundecanoic acid is almost unaffected. The process by which the shorter-chain SAM layers are partially removed is not fully understood because these compounds do not absorb significantly in the 365 nm region of the spectrum! Significantly, this study shows that acid catalysis photolysis of thiol-on-gold SAMs needs to be used with caution. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Related Products of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Related Products of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Pyrene-imidazole conjugate as a fluorescent sensor for the sequential detection of iron(III) and histidine in aqueous solution was written by Wang, Jing;Jiang, Huihui;Liu, Hai-Bo;Liang, Lebao;Tao, Junrong. And the article was included in Spectrochimica Acta in 2020.COA of Formula: C18H11BrO The following contents are mentioned in the article:

We developed PIM (I), a pyrene-based fluorescence sensor bearing an imidazole moiety and a carbonyl group as the binding sites for Fe³⁺ ions. The pyrene-based control compounds 1 and 2 were synthesized to demonstrate the structure-activity relationships. Compound 1 (II), which contained a thiazoline moiety and a carbonyl group, displayed high selectivity for Cu²⁺ ions. This property indicated that heterocycles play an important role in the metal ion selectivity modulation. Compound 2 (III), which lacked a carbonyl group, did not display metal ion selectivity. This characteristic demonstrated that introducing an addnl. recognition unit (cooperative recognition strategy) should be an effective way to improve metal ion selectivity. Furthermore, the PIM-Fe³⁺ ensemble can serve as a fluorescent sensor for histidine (His) detection via the removal of Fe³⁺ from the ensemble by His and the release of PIM. The sequential detection of Fe³⁺ and His exhibited on-off-on phenomenon, and the Fe³⁺ and His detection limits were 0.11 and 3.06 μM, resp. These results will help in the further enhancement or modulation of metal ion selectivity in the development of fluorescent sensor systems. Moreover, the organic-metal ensemble provides an effective platform for detecting amino acids through the displacement strategy. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5COA of Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.COA of Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Boron-Nitrogen-Doped Nanographenes: A Synthetic Tale from Borazine Precursors was written by Dosso, Jacopo;Battisti, Tommaso;Ward, Benjamin D.;Demitri, Nicola;Hughes, Colan E.;Williams, P. Andrew;Harris, Kenneth D. M.;Bonifazi, Davide. And the article was included in Chemistry – A European Journal in 2020.Reference of 1890136-54-5 The following contents are mentioned in the article:

In this work, a comprehensive account of the authors’ synthetic efforts to prepare borazino-doped hexabenzocoronenes by using the Friedel-Crafts-type electrophilic aromatic substitution is reported. Hexafluoro-functionalized aryl borazines, bearing an ortho fluoride leaving group on each of the N- and B-aryl rings, was shown to lead to cascade-type electrophilic aromatic substitution events in the stepwise C-C bond formation, giving higher yields of borazinocoronenes than those obtained with borazine precursors bearing fluoride leaving groups at the ortho positions of the B-aryl substituents. By using this pathway, an unprecedented boroxadizine-doped PAH (I) featuring a gulf-type periphery could be isolated, and its structure proven by single-crystal X-ray diffraction anal. Mechanistic studies on the stepwise Friedel-Crafts-type cyclization suggest that the mechanism of the planarization reaction proceeds through extension of the π system. To appraise the doping effect of the boroxadizine unit on the optoelectronic properties of topol.-equivalent mol. graphenes, the all-carbon and pyrylium PAH analogs, all featuring a gulf-type periphery, were also prepared As already shown for the borazino-doped hexabenzocoronene, the replacement of the central benzene ring by its B₃N₂O congener widens the HOMO-LUMO gap and dramatically enhances the fluorescence quantum yield. This study involved multiple reactions and reactants, such as 2-Bromo-5′-phenyl-1,1′:3′,1”-terphenyl (cas: 1890136-54-5Reference of 1890136-54-5).

2-Bromo-5′-phenyl-1,1′:3′,1”-terphenyl (cas: 1890136-54-5) belongs to organobromine compounds. Organo bromine compounds are versatile compounds and are widely used in diverse fields. Organo bromine derivatives are used in the dye sector, as an indicator in analytical chemistry (Bromothymol blue is a popular indicator). The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Reference of 1890136-54-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Covalent functionalization of nanosheets of MoS₂ and MoSe₂ by substituted benzenes and other organic molecules was written by Vishnoi, Pratap;Sampath, Archana;Waghmare, Umesh V.;Rao, C. N. R.. And the article was included in Chemistry – A European Journal in 2017.Safety of 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Covalent functionalization has been effectively employed to attach benzene functionalities to MoS₂ and MoSe₂ nanosheets by the reaction with para-substituted iodobenzenes bearing -OCH₃, -H, and -NO₂ as the substituents, where the electron-donating and electron-withdrawing power of the para substituent varies significantly. The functionalization is based on the formation of a C-S or C-Se linkage at the expense of the C-I bond on reaction of the iodobenzene with electron-rich 1T-MoS₂ or 1T-MoSe₂. The degree of functionalization is in the range 4-24 % range, the value increases with the electron-withdrawing power of the para substituent. Semiconducting 2H-MoS₂ and 2H-MoSe₂ nanosheets can also be functionalized with iodobenzene by carrying out the reaction in the presence of a Pd⁰ catalyst. We have also carried out functionalization of 1T-MoS₂ with pyrene, coumarin, and porphyrin derivatives By using first-principles d. functional calculations, we show that the bonding of the functional groups with the 1T phase is stronger than with the 2H phase. This is reflected in notable changes in the electronic structure of the former upon functionalization; a gap opens up in the electronic spectrum of the 1T phase. Functionalization with para-substituted benzenes leads to a change in the work function. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Safety of 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Safety of 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Direct in situ labeling of target drugs with a fluorophore probe to improve MALDI-MS detection sensitivity in micro-liter plasma was written by Li, Yi-Shan;Lu, Chi-Yu. And the article was included in Scientific Reports in 2019.Formula: C18H11BrO The following contents are mentioned in the article:

Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used for symptomatic relief from fever, inflammation, and chronic pain associated with a variety of human disorders. Long-term usage of these drugs can result in severe syndromes; hence, their dose should be controlled carefully and their side effects such as Stevens-Johnson syndrome, toxic epidermal necrolysis, phototoxicity, acute interstitial nephritis, gastrointestinal bleeding, cardiovascular diseases, and liver injury should be considered. Furthermore, the widely used combination of NSAIDs as over-the-counter (OTC) drugs with other drugs leads to adverse drug-drug interactions. Therefore, development of a throughput method to rapidly screen 20 NSAIDs in biol. samples is necessary to safeguard human health. In this work, we selected a suitable fluorophore probe coupled with in situ micro-labeling (<2 min) on stainless plate for the fast detection of NSAIDs in plasma samples at the micro-liter level (5μL) without complicated sample preparation and separation Every step undertaken in the protocol was also at the micro-liter level; thus, a small amount of blood collected from the human finger will suffice to determine the drug concentration in blood using the proposed method. Furthermore, the proposed method we developed was also matched the modern trends of green anal. chem. towards miniaturization of anal. methodologies. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Formula: C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. The principal reactions for organobromides include dehydrobromination, Grignard reactions, reductive coupling, and nucleophilic substitution.Formula: C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Rhodium-Catalyzed C-H Activation of Phenacyl Ammonium Salts Assisted by an Oxidizing C-N Bond: A Combination of Experimental and Theoretical Studies was written by Yu, Songjie;Liu, Song;Lan, Yu;Wan, Boshun;Li, Xingwei. And the article was included in Journal of the American Chemical Society in 2015.SDS of cas: 80480-15-5 The following contents are mentioned in the article:

Rh(III)-catalyzed C-H activation assisted by an oxidizing directing group has evolved to a mild and redox-economic strategy for the construction of heterocycles. Despite the success, these coupling systems are currently limited to cleavage of an oxidizing N-O or N-N bond. Cleavage of an oxidizing C-N bond, which allows for complementary carbocycle synthesis, is unprecedented. α-Ammonium acetophenones with an oxidizing C-N bond were designed as substrates for Rh(III)-catalyzed C-H activation under redox-neutral conditions. The coupling with α-diazo esters afforded benzocyclopentanones, and the coupling with unactivated alkenes such as styrenes and aliphatic olefins gave ortho-olefinated acetophenoes. In both systems the reactions proceeded with a broad scope, high efficiency, and functional group tolerance. Also, efficient 1-pot coupling of diazo esters was realized starting from α-bromoacetophenones and triethylamine. The reaction mechanism for the coupling with diazo esters was studied by a combination of exptl. and theor. methods. In particular, three distinct mechanistic pathways were scrutinized by DFT studies, which revealed that the C-H activation occurs via a C-bound enolate-assisted concerted metalation-deprotonation mechanism and is rate-limiting. In subsequent C-C formation steps, the lowest energy pathway involves two rhodium carbene species as key intermediates. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5SDS of cas: 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. alpha-Bromoesters are employed in the Reformatsky reaction for the synthesis of beta-hydroxyesters. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.SDS of cas: 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The effect of iron catalyzed graphitization on the textural properties of carbonized cellulose: Magnetically separable graphitic carbon bodies for catalysis and remediation was written by Hoekstra, Jacco;Beale, Andrew M.;Soulimani, Fouad;Versluijs-Helder, Marjan;van de Kleut, Dirk;Koelewijn, Jacobus M.;Geus, John W.;Jenneskens, Leonardus W.. And the article was included in Carbon in 2016.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Whereas pyrolysis of pristine microcrystalline cellulose spheres yields nonporous amorphous carbon bodies, pyrolysis of microcrystalline cellulose spheres loaded with iron salts leads to the formation of magnetically separable mesoporous graphitic carbon bodies. The microcrystalline cellulose spheres loaded with either iron(III) nitrate, ammonium iron(III) citrate or iron(III) chloride were pyrolyzed up to 800°. Temperature dependent x-ray diffraction anal. shows that the iron salts are transformed into iron oxide nanoparticles; their size and distribution are influenced by the anion of the iron salt. The iron oxide nanoparticles are subsequently carbothermally reduced by the amorphous carbon that is obtained from the pyrolysis of the microcrystalline cellulose. Next, the iron nanoparticles catalyze the conversion of the amorphous carbon to graphitic carbon nanostructures as shown with x-ray diffraction, electron microscopy and Raman spectroscopy. The extent of graphitization depends on the iron nanoparticle size. Nitrogen physisorption measurements show that this graphitization process introduces mesopores into the carbon bodies. The benefits of the properties of the resulting carbon bodies (ferromagnetic character, graphitic content, mesoporosity) are discussed in connection with applications in liquid-phase catalysis and remediation. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. Organobromine compounds have fallen under increased scrutiny for their environmental impact. One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine.Recommanded Product: 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Elastomeric azo-polyurethanes containing fluorescent pyrene and their photo activity was written by Buruiana, Emil C.;Buruiana, Tinca;Zamfir, Mirela;Pohoata, Valentin;Donescu, Dan. And the article was included in Designed Monomers and Polymers in 2007.Application of 80480-15-5 The following contents are mentioned in the article:

Two bichromophoric polyetherurethanes with a small number of pyrene rings on the quaternary ammonium groups and photoisomerizable azobenzene chromophore attached to the soft (AzPUC-Py1) or hard segment (AzPUC-Py2) of the polymeric backbone were synthesized and characterized. The effect of polymer structure on the trans-cis and cis-trans photo(thermo)isomerization of azobenzene in thin films induced by UV light (λ = 365 nm) was studied using UV spectroscopy, and in every case the quality of sensitizer of the pyrene was not in evidence. Also, a better photochromic response in the film containing azobenzene in the polyether component compared to that induced of the same chromophore in the hard segment was registered. Properties in the solution and thin films were examined in relation with the fluorescence of pyrene mol. excited at λ_exc 335 nm. Results of the fluorescence study accompanied of a fluorescence quenching through N,N-diethylaniline (DEA) sustain that these polymers could be used for the detection of amines up to a concentration of 1.57 × 10^-3 mol/L (AzPUC-Py1) and 3.14 × 10^-3 mol/L (AzPUC-Py2), resp., in DMF solution Compared to the polymer solution, in the polymer film exposed to DEA-saturated vapors ∼30% monomer fluorescence quenching was found after 90 min. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Application of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Application of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis and In Vitro Antiproliferative Activity of Thiazole-Based Nitrogen Mustards: The Hydrogen Bonding Interaction between Model Systems and Nucleobases was written by Laczkowski, Krzysztof Z.;Misiura, Konrad;Switalska, Marta;Wietrzyk, Joanna;Laczkowska, Angelika Baranowska;Fernandez, Berta;Paneth, Agata;Plech, Tomasz. And the article was included in Anti-Cancer Agents in Medicinal Chemistry in 2014.Related Products of 80480-15-5 The following contents are mentioned in the article:

Synthesis, characterization and investigation of antiproliferative activity of eight thiazole-based nitrogen mustard against human cancer cells lines (MV4-11, A549, HCT116 and MCF-7) and normal mouse fibroblast (BALB/3T3) are presented. Their structures were determined using NMR, FAB MS, HRMS and elemental analyses. Among the derivatives, 3a, 3b, 3e and 3h were found to exhibit high activity against human leukemia MV4-11 cells with IC50 values of 0.634-3.61 μg/mL. The cytotoxic activity of compound 3a against BALB/3T3 cells is up to 40 times lower than against cancer cell lines. Our data indicated also that compound 3e had very strong activity against MCF-7 and HCT116 with IC50 equal to 2.32 μg/mL and 2.81 μg/mL, resp. Their activity was similar to the activity of cis-platin, which is clin. used as anticancer drug in the treatment of human solid tumors. We also perform quantum chem. calculation of interaction and binding energies in complexes of model systems and 3e with DNA bases. Interaction of real drug 3e with guanine is much stronger than with the remaining nucleobases, and the strongest among all investigated complexes. Computer simulations were performed with ATP-binding domain and DNA-binding site of hTopoII. Compounds 3a-h were recognized as potential inhibitors of hTopoII. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Related Products of 80480-15-5).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Bromine is more electronegative than carbon (2.9 vs 2.5). Consequently, the carbon in a carbon–bromine bond is electrophilic, i.e. alkyl bromides are alkylating agents. Many of the alkyl bromine derivatives are excellent alkylating agents since bromides are good leaving groups. Tribromides, like tetrabutylammonium tribromide, are used as a solid source of bromine. N-bromosuccimide (NBS) is used for the selective bromination of allylic bonds.Related Products of 80480-15-5

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Polymerization of n-butyl acrylate photoinitiated by 1-(bromoacetyl)pyrene and its arsonium salt was written by Mishra, Anuradha;Daswal, Swati. And the article was included in Journal of Macromolecular Science in 2006.Computed Properties of C18H11BrO The following contents are mentioned in the article:

A comparative study on the photoinitiating efficiency of pyrene (Py), 1-acetylpyrene (AP), 1-(bromoacetyl)pyrene (BP), and 1-acetylpyrene triphenylarsonium bromide (APAS) for polymerization of Bu acrylate (BA) was done. Exptl. investigation of the kinetics of free radical solution polymerization at 25±0.2°C using all four photoinitiators showed that pyrene was completely ineffective in initiating the polymerization under all conditions employed, whereas AP was able to initiate polymerization Incorporation of a bromo group into AP markedly accelerated the rate of UV-induced polymerization Further modification of the bromo derivative (BP) to its arsonium salt (APAS) produced a less effective initiator. The kinetics and mechanism of polymerization using BP and APAS as initiators have been investigated in detail. The polymerization with BP followed non-ideal kinetics (Rp∝[BP]^0.8 [BA]^0.98) with respect to initiator concentration, whereas ideal kinetics (Rp∝[APAS]^0.49 [BA]^1.07) was observed when APAS was used as an initiator. This unusual kinetic behavior for the BP-BA system can be interpreted in light of degradative transfer and the emergence of occlusion. The kinetic data proved that BP was a more effective and faster initiator than APAS. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Computed Properties of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Many of the organo bromine compounds are relatively nonpolar. Bromine is more electronegative than carbon (2.8 vs 2.5) and hence the carbon in a carbon–bromine bond is electrophilic in nature. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Computed Properties of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary