Tag: 300-400

Determination of dialkyl phosphates as breakdown products of organophosphorus insecticides in fruit juices by HPTLC with fluorescence detection was written by Schwack, Wolfgang;Zeisler, Tatjana;Stiefel, Constanze. And the article was included in Journal of AOAC International in 2009.Name: 2-Bromo-1-(pyren-1-yl)ethanone The following contents are mentioned in the article:

Dialkyl phosphates (DAP) are common degradation products of organophosphorus pesticides that are used as urinary biomarkers for human exposure. An HPTLC method was developed for the quant. determination of DAP in fruit juices, i.e., di-Me phosphate (DMP), di-Me thiophosphate (DMTP), di-Et phosphate (DEP), and di-Et thiophosphate (DETP). Di-Bu phosphate (DBP) was used as an internal standard The method was based on precipitation of fruit acids in the presence of barium chloride and acetonitrile and liquid-liquid extraction with acetonitrile-diethyl ether. Extracted DAP were derivatized with 1-(bromoacetyl)pyrene (BAP), and the BAP derivatives separated on HPTLC amino plates with dichloromethane as the mobile phase. Densitometry was performed by measurement of fluorescence at 366/>400 nm. The limit of quantification (LOQ) values were between 0.8 and 1.4 ng/zone. Fluorescence enhancement was achieved by dipping the plate into a paraffin oil solution, increasing the sensitivity and resulting in and LOQ of 0.5-0.6 ng/zone. Repeatabilities with relative standard deviations of ≤3.5% (n = 5, at 15-20 ng/zone) and coefficients of correlation of 0.9999 were highly satisfactory for rapid trace anal. of DAP in the fruit juices by HPTLC. The mean recoveries from apple juice spiked at 0.5 mg/L were 74, 83, 70, and 57% for DMP, DEP, DMTP, and DETP, resp. If an application volume of 5 μL of apple juice extract was applied, the LOQ in apple juice was 300 μg/L. However, this can be lowered by application of higher volumes (up to 50 μL) or a more concentrated derivatization batch. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Name: 2-Bromo-1-(pyren-1-yl)ethanone).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most of the natural organobromine compounds are produced by marine organisms, and several brominated metabolites with antibacterial, antitumor, antiviral, and antifungal activity have been isolated from seaweed, sponges, corals, molluscs, and others. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Name: 2-Bromo-1-(pyren-1-yl)ethanone

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A High-Barrier Molecular Balance for Studying Face-to-Face Arene-Arene Interactions in the Solid State and in Solution was written by Chong, Yong S.;Carroll, William R.;Burns, William G.;Smith, Mark D.;Shimizu, Ken D.. And the article was included in Chemistry – A European Journal in 2009.Synthetic Route of C18H11BrO The following contents are mentioned in the article:

An atropisomeric mol. balance was developed to study face-to-face arene-arene interactions. The balance has a large central 1,4,5,8-naphthalenediimide surface that forms intramol. arene-arene interactions with two pendent arms. The balance adopts distinct syn and anti isomers with varying numbers of intramol. interactions. Thus, the strength of the arene-arene interaction could be quant. measured by NMR spectroscopy from the anti/syn ratios. The size of the arene arms was easily varied, which allowed examination of the relation between arene size and strength of the interaction. A nonlinear size dependence was observed in solution with larger arene arms having a disproportionately stronger arene-arene interaction. The intramol. arene-arene interactions were also characterized in the solid state by x-ray crystallog. These studies were facilitated by the kinetic stability of the syn and anti isomers at room temperature due to the high isomerization barrier (ΔG = 27.0 kcal mol^-1). Thus, the anti isomer could be selectively isolated and crystallized in its folded conformation. The x-ray structures confirmed that the anti isomers formed two strong intramol. arene-arene interactions with face-to-face geometries. The solid-state structure anal. also reveals that the rigid framework may contribute to the observed nonlinear size trend. The acetate linker is slightly too long, which selectively destabilizes the balances with smaller arene arms. The larger arene arms are able to compensate for the longer linker and form effective intramol. arene-arene interactions. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Synthetic Route of C18H11BrO).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. In the pharmaceutical industry organo bromine derivatives are used as sedatives, vasodilators, antiseptic agents, and anticancer agents.Synthetic Route of C18H11BrO

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthesis, characterization, photophysics and electrophosphorescent applications of phosphorescent platinum cyclometalated complexes with 9-arylcarbazole moieties was written by Ho, Cheuk-Lam;Wong, Wai-Yeung;Yao, Bing;Xie, Zhiyuen;Wang, Lixiang;Lin, Zhenyang. And the article was included in Journal of Organometallic Chemistry in 2009.Product Details of 922721-30-0 The following contents are mentioned in the article:

Cyclometalating Pt(II) complexes with substituted 9-arylcarbazolyl chromophores were synthesized and characterized. These complexes are thermally stable and most of them were characterized by x-ray crystallog. The phosphorescence emissions of the complexes are dominated by ³MLCT excited states. The excited state properties of these complexes can be modulated by varying the electronic characteristics of the cyclometalating ligands via substituent effects, thus allowing the emission to be tuned from bright green to yellow, orange and red light. The correlation between the functional properties of these metallophosphors and the results of d. functional theory calculations was made. Because of the propensity of the electron-rich carbazolyl group to facilitate hole injection/transport, the presence of such moiety can increase the HOMO levels and improve the charge balance in the resulting complexes relative to the parent Pt(II) phosphor with 2-phenylpyridine ligand. The solution-processed electrophosphorescent organic light-emitting diodes doped with these Pt-based phosphors were fabricated which showed a maximum external quantum efficiency of 2.77% for the best device, corresponding to a power efficiency of 3.48 lm/W and a luminance efficiency of 8.49 cd/A. The present work enables the rational design of Pt-carbazolyl electrophosphors by synthetically tailoring the structure of carbazolylpyridine ring that can permit good color-tuning versatility suitable for multi-color display technol. This study involved multiple reactions and reactants, such as 3-Bromo-9-(4-fluorophenyl)-9H-carbazole (cas: 922721-30-0Product Details of 922721-30-0).

3-Bromo-9-(4-fluorophenyl)-9H-carbazole (cas: 922721-30-0) belongs to organobromine compounds. Bromo compounds are employed in a variety of metal-catalyzed coupling reactions. They are also ideal candidates for the synthesis of Grignard reagents that have wide-applicability in organic synthesis. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Product Details of 922721-30-0

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chiral Bidentate Boryl Ligand Enabled Iridium-Catalyzed Asymmetric C(sp²)-H Borylation of Diarylmethylamines was written by Zou, Xiaoliang;Zhao, Haonan;Li, Yinwu;Gao, Qian;Ke, Zhuofeng;Senmiao Xu. And the article was included in Journal of the American Chemical Society in 2019.Application In Synthesis of 2-Bromo-5′-phenyl-1,1′:3′,1”-terphenyl The following contents are mentioned in the article:

Optically active organoboronic acids and their derivatives are an important family of target compounds in organic chem., catalysis, and medicinal chem. Yet there are rare asym. catalytic examples reported for the synthesis of these compounds via atom and step economic ways. Herein, we report a chelate-directed iridium-catalyzed asym. C(sp²)-H borylation of aromatic C-H bonds directed by free amine groups. The success of these transformations relies on a novel family of chiral bidentate boryl ligands (L). They can be synthesized straightforwardly in three steps starting from readily available (S,S)-1,2-diphenyl-1,2-ethanediamie ((S,S)-DPEN). The Ir-catalyzed C(sp²)-H borylation comprises two parts. The first part is desymmetrization of prochiral diarylmethylamines. In the presence of L3/Ir, a vast array of corresponding borylated products were obtained with high regioselectivity and good to excellent enantioselectivities (26 examples, up to 96% ee). The second part, kinetic resolution of racemic diarylmethylamines, was also conducted. Good selectivity values (up to 68%, 11 examples) were obtained when L8 was used. We also demonstrated the synthetic utility of the current method on gram-scale reaction for several transformations. The C-B bonds of borylated products could be converted to a variety of functionalities including C-O, C-C, C-C, C-Br, and C-P bonds. Finally, we performed DFT calculations of desymmetrization to understand its reaction pathways. This study involved multiple reactions and reactants, such as 2-Bromo-5′-phenyl-1,1′:3′,1”-terphenyl (cas: 1890136-54-5Application In Synthesis of 2-Bromo-5′-phenyl-1,1′:3′,1”-terphenyl).

2-Bromo-5′-phenyl-1,1′:3′,1”-terphenyl (cas: 1890136-54-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. The reactivity of organobromine compounds resembles but is intermediate between the reactivity of organochlorine and organoiodine compounds. For many applications, organobromides represent a compromise of reactivity and cost.Application In Synthesis of 2-Bromo-5′-phenyl-1,1′:3′,1”-terphenyl

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Catalytic activity and facile recovery of a cyclometalated N-heterocyclic carbene palladium(II) complex immobilized by non-covalent interactions on reduced graphene oxide was written by Karami, Kazem;Ramezanpour, Azar;Zakariazadeh, Mostafa;Silvestru, Cristian. And the article was included in Applied Organometallic Chemistry in 2019.Category: bromides-buliding-blocks The following contents are mentioned in the article:

The growing concern about the potentially adverse effects of the production of chem. compounds on the sustainable development of the environment has led to a great deal of efforts to search for low-cost and environmentally friendly catalytic systems. A pyrene-tagged N-heterocyclic carbene palladacycle complex ([Pd{(C,N)C₆H₄CH₂NH(Et)}(Imd-P)Br]) was prepared by reacting imidazolium salt with dimer ([Pd₂{(C,N)C₆H₄CH₂NH(Et)}₂(μ-OAc)₂]). Then, it was immobilized onto the surface of reduced graphene oxide (rGO) via π-π stacking forces. The hybrid compound ((NHC)Pd-rGO) was made in a one-step process. Various techniques were employed to characterize the compound In addition, computational studies were used to verify the interaction between the Pd complex and rGO. The catalytic activity of the mol. complex and hybrid material was evaluated in both Suzuki-Miyaura cross-coupling reactions and reduction of p-nitrophenol to p-aminophenol. The catalytic activity of the hybrid material was enhanced in comparison with the corresponding homogeneous analog. Thus, rGO seems to play a significant role in catalytic activity. Hot filtration experiments show the heterogeneous nature of the catalyst resulting from the strong interaction between pyrene and graphene. The hybrid (NHC)Pd-rGO material could be recycled up to six times with no decrease in catalytic activity. This study involved multiple reactions and reactants, such as 2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5Category: bromides-buliding-blocks).

2-Bromo-1-(pyren-1-yl)ethanone (cas: 80480-15-5) belongs to organobromine compounds. Most organobromine compounds, like most organohalide compounds, are relatively nonpolar. When the molecular ion is detected, the bromine and chlorine isotope patterns are very distinct, but caution is to be exercised for certain mixed chlorinated/brominated compounds, which can look similar to homohalogen patterns.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Chun; Su, Meihui; Luo, Pei; Liu, Yanan; Yang, Feng; Li, Changhua published an article in 2021. The article was titled 《A Photosensitive Polymeric Carrier with a Renewable Singlet Oxygen Reservoir Regulated by Two NIR Beams for Enhanced Antitumor Phototherapy》, and you may find the article in Small.Application In Synthesis of 9,10-Dibromoanthracene The information in the text is summarized as follows:

Photodynamic therapy (PDT), which utilizes photosensitizer to convert mol. oxygen into singlet oxygen (1O2) upon laser irradiation to ablate tumors, will exacerbate the already oxygen shortage of most solid tumors and is thus self-limiting. Herein, a sophisticated photosensitive polymeric material (An-NP) that allows sustained 1O2 generation and sufficient oxygen supply during the entire phototherapy is engineered by alternatively applying PDT and photothermal therapy (PTT) controlled by two NIR laser beams. In addition to a photosensitizer that generates 1O2, An-NP consists of two other key components: a molecularly designed anthracene derivative capable of trapping/releasing 1O2 with superior reversibility and a dye J-aggregate with superb photothermal performance. Thus, in 655 nm laser-triggered PDT process, An-NP generates abundant 1O2 with extra 1O2 being trapped via the conversion into EPO-NP; while in the subsequent 785 nm laser-driven PTT process, the converted EPO-NP undergoes thermolysis to liberate the captured 1O2 and regenerates An-NP. The intratumoral oxygen level can be replenished during the PTT cycle for the next round of PDT to generate 1O2. The working principle and phototherapy efficacy are preliminarily demonstrated in living cells and tumor-bearing mice, resp. In the experiment, the researchers used many compounds, for example, 9,10-Dibromoanthracene(cas: 523-27-3Application In Synthesis of 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) is a dibrominated polycyclic aromatic hydrocarbon (PAH). 9,10-Dibromoanthracene is often used as an energy acceptor and activator in reactions that produce chemiluminescence.Application In Synthesis of 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Conjugated polymer self-assembled with graphene: Synthesis and electrochemical 1-hydroxypyrene sensor》 was published in Polymer in 2020. These research results belong to Pang, Yuehong; Yang, Nianci; Shen, Xiaofang; Zhang, Yi; Feng, Liheng. COA of Formula: C14H8Br2 The article mentions the following:

Urinary 1-hydroxypyrene (1-OHP), one of the metabolite of polycyclic aromatic hydrocarbons (PAHs), has been extensively applied as a biomarker of animals and human exposure to PAHs. Herein, we synthesized a novel conjugated polymer poly-8-methoxy-7-methyl-5-(10-anthracen-9-yl)quinolone (PMMAYQ) using Suzuki coupling reaction, and then fabricated a homogeneous PMMAYQ/grahene multilayer film via layer-by-layer self-assembly technique and applied for electrochem. sensing of 1-OHP. Under the optimal conditions, {PMMAYQ-Graphene}16 modified glass carbon electrode exhibited excellent response for detection of 1-OHP. A linear range from 0.5 to 120 nM was obtained with a low detection limit of 0.07 nM (S/N = 3) and a sensitivity of 0.5539μA/μM. The electrochem. sensor exhibited excellent stability, accepted repeatability, and good selectivity. The developed method was employed for determination of 1-OHP in human urine samples and recoveries in the range of 95.6%-107.1% were achieved. The experimental process involved the reaction of 9,10-Dibromoanthracene(cas: 523-27-3COA of Formula: C14H8Br2)

9,10-Dibromoanthracene(cas: 523-27-3) can be sublimated and oxidized to generate anthraquinone. Soluble in hot benzene and hot toluene, slightly soluble in alcohol, ether and cold benzene, insoluble in water.COA of Formula: C14H8Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《An effective synthesis of ursodeoxycholic acid from dehydroepiandrosterone》 was written by Chen, Wang; Hu, Daihua; Feng, Zili; Liu, Zhaopeng. HPLC of Formula: 1530-32-1This research focused onursodeoxycholic acid preparation Mitsunobu inversion Luche regioselective allyl oxidation; Dehydroepiandrosterone; Synthesis; Ursodeoxycholic acid. The article conveys some information:

A novel synthetic route of producing ursodeoxycholic acid (UDCA, I) was developed through multiple reactions from plant-source dehydroepiandrosterone (DHEA), with a Mitsunobu reaction and regioselective allyl oxidationat as the key steps. The reaction conditions of the key allyl oxidation reaction were also investigated and optimized, including solvent, oxidant and reaction temperature In this novel route for the preparation of UDCA, most of the reaction steps have high conversions and overall yield up to 35% for 8 steps. Since all starting materials are cost-effective, com. available and effectively avoided the risk of animal derived raw materials, this promising synthetic route offers economical and efficient strategies for potential production of UDCA. In the experimental materials used by the author, we found Ethyltriphenylphosphonium bromide(cas: 1530-32-1HPLC of Formula: 1530-32-1)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.HPLC of Formula: 1530-32-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

HPLC of Formula: 6825-20-3In 2020 ,《Proton Transfer Can Govern Regioselectivity Assisted by Iron Catalysis》 appeared in iScience. The author of the article were Li, Yudong; Fu, Liyan; Jiang, Xiaolin; Zhao, Dongmei; Wang, Hui-Fang; Xia, Chungu; Li, Yuehui. The article conveys some information:

Ortho-selective aromatic C-H functionalization is frequently used in organic synthesis and chem./pharmaceutical industries. However, this reaction relies heavily on the use of directing groups suffering from limited substrate scope and extra steps to put on and remove the directing/protecting groups. Herein authors present the previously neglected concept that enables good to nearly complete selective ortho position. Proton transfer was utilized to tune the electron d. on the aryl ring and determine the positional selectivity of electrophilic substitution. Consistently with deuteration experiments and DFT studies, this work demonstrates that acid-promoted proton transfer directs accelerated ortho-selective halogenation of NH/OH contained aromatic amines/phenols with excellent selectivity (>40 examples; up to 98:2 ortho/para selectivity). The application potential of this Fe-catalyzed method is demonstrated by the convenient synthesis of three alkaloids and tizanidine. This report raises the possibility that proton transfer could serve as the basis of developing new selective C-H functionalization reactions. After reading the article, we found that the author used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3HPLC of Formula: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.HPLC of Formula: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Quality Control of 9,10-DibromoanthraceneIn 2022 ,《POSS-based fluorescence sensor for rapid analysis of β-carotene in health products》 appeared in Luminescence. The author of the article were Li, Dan; Zhou, Peipei; Hu, Yufei; Li, Gongke; Xia, Ling. The article conveys some information:

In recent years, fluorescent organic-inorganic hybrid nanomaterials have received much interest as potential fluorescent sensor materials. In this study, fluorescent organic-inorganic hybrid nanomaterials (POSS@ANT) were created using polyhedral oligomeric silsesquioxane as the precursor and 9,10-bromoanthracene as the monomer. The morphol. and composition of POSS@ANT, as well as its pore characteristics and fluorescence properties were studied. POSS@ANT displayed steady fluorescence emission at an excitation wavelength of 374 nm. Next, a β-carotene fluorescence sensor was developed using the capacity of β-carotene to quench the fluorescence of POSS@ANT. The quenching process is linked to acceptor electron transfer and energy transfer, and the sensor has a high selectivity for β-carotene. This β-carotene fluorescence anal. method that we established has a linear range of 0.2-4.3 mg/L and a detection limit of 0.081 mg/L. Finally, it was used to quantify β-carotene in health products, the recovery rate was 91.1-109.9%, the relative standard deviation (RSD) was 2.2-4.3%, and the results were comparable with the results of high-performance liquid chromatog. The approach is reliable and can be used to determine β-carotene in health products. The results came from multiple reactions, including the reaction of 9,10-Dibromoanthracene(cas: 523-27-3Quality Control of 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) is a dibrominated polycyclic aromatic hydrocarbon (PAH). 9,10-Dibromoanthracene is often used as an energy acceptor and activator in reactions that produce chemiluminescence.Quality Control of 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary