Tag: 300-400

Li, Ping; Lee, Boon Chong; Zhang, Xiaoxiang; Koh, Ming Joo published an article in 2022. The article was titled 《Base-Mediated Site-Selective Hydroamination of Alkenes》, and you may find the article in Synthesis.Application In Synthesis of Ethyltriphenylphosphonium bromide The information in the text is summarized as follows:

A base-mediated hydroamination protocol, using substoichiometric amounts of a hydrosilane and potassium tert-butoxide, that operates under mild conditions at 30° is presented. Many aryl- and heteroatom-substituted olefins as well as arylamines are tolerated, affording the desired products with complete regioselectivity. Preliminary mechanistic investigations reveal a non-radical pathway for hydroamination. A sequential remote hydroamination strategy involving an initial Fe-catalyzed olefin isomerization followed by the base-mediated hydroamination was also developed to directly access β-arylamines from terminal aliphatic alkenes. In addition to this study using Ethyltriphenylphosphonium bromide, there are many other studies that have used Ethyltriphenylphosphonium bromide(cas: 1530-32-1Application In Synthesis of Ethyltriphenylphosphonium bromide) was used in this study.

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.Application In Synthesis of Ethyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Yang, Hui; Xing, Baoyan; Zhao, Jianguo; Ma, Guibin published an article in Polyhedron. The title of the article was 《Methoxyl-substituted phosphine ligand properties and a case study of formation adducts to indium(III) bromide by DFT calculations》.Formula: Br3In The author mentioned the following in the article:

Six bulky triphenylphosphine ligands containing substituted methoxyl groups (tris(2,4,6-trimethoxyphenyl)phosphine (TMP), tris(2,6-dimethoxyphenyl)phosphine (TDP), tris(o-methoxyphenyl)phosphine (o-Anis3P), tris(p-methoxyphenyl)phosphine (p-Anis3P), tris(m-methoxyphenyl)phosphine (m-Anis3P) and triphenylphosphine (PPh3)) were studied by DFT (d. functional theory) calculations and exptl. solution/solid-state 31P NMR spectroscopy. The basicity and binding ability of these substituted ligands, proven by comparison of structural data with DFT-predicted data, are in the order TMP > TDP > o-Anis3P > p-Anis3P > m-Anis3P > PPh3. Mol. structures for InBr3 with bulky ligands (TMP, TDP, o-Anis3P, p-Anis3P, m-Anis3P and PPh3) were calculated using DFT. P-In bond distances generated from these six optimized mol. structures and the calculated intramol. interaction energies are in agreement with the ligand properties, with strong donation ability for those with the short bond distance; the In-P bond distance from shortest to longest follows a similar trend as predicted by DFT calculations DFT calculations for these adducts show that methoxyl substitution to triphenylphosphine (PPh3) ligands contributed to its electron donor ability resulting in lower P-In bond distances with relatively large bond interaction energies. In the part of experimental materials, we found many familiar compounds, such as Indium(III) bromide(cas: 13465-09-3Formula: Br3In)

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Formula: Br3In

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Sei, Kento; Wang, Qi; Tokumura, Masahiro; Miyake, Yuichi; Amagai, Takashi published an article in 2021. The article was titled 《Accurate and ultrasensitive determination of 72 parent and halogenated polycyclic aromatic hydrocarbons in a variety of environmental samples via gas chromatography-triple quadrupole mass spectrometry》, and you may find the article in Chemosphere.Quality Control of 9,10-Dibromoanthracene The information in the text is summarized as follows:

Polycyclic aromatic hydrocarbons (PAHs) and their halogenated derivatives (XPAHs) are ubiquitous in various environmental media. Anal. problems, however, make it difficult to accurately determine their concentrations To develop a satisfactory anal. method suitable for a diversity of PAHs and XPAHs in multiple environmental samples, we evaluated three com. anal. columns (DB-5MS, Select PAH, and Rxi-PAH) for better chromatog. separation and optimized the anal. conditions for gas chromatog.-triple quadrupole mass spectrometry (GC-MS/MS). Comparison of the abilities of the columns to sep. peaks revealed that the Rxi-PAH was the best column for both PAH and XPAH analyses. Optimization of anal. conditions for GC-MS/MS resulted in sensitivities for PAHs and XPAHs that were 4.2-fold-2600-fold higher than the sensitivities of GC-high-resolution MS (GC-HRMS) (an example of a traditional anal. method). Although there were no statistically significant differences between the instrumental detection limits (IDLs) of PAHs and XPAHs measured by GC-HRMS, the IDLs of XPAHs were significantly lower than those of PAHs when measured by GC-MS/MS. This difference could be attributed to the unique ionization patterns of XPAHs in the GC-MS/MS anal., which suppressed background noise and increased the anal. sensitivity. Analyses of PAHs and XPAHs in grilled chicken, vehicle exhaust, sea sediment, ambient air, and indoor dust via the anal. method optimized in this study revealed that the proposed method was sufficiently sensitive, comprehensive, and versatile for risk assessment purposes, and could eliminate interferences associated with the co-elution of target PAHs and XPAHs. In the experimental materials used by the author, we found 9,10-Dibromoanthracene(cas: 523-27-3Quality Control of 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) is a dibrominated polycyclic aromatic hydrocarbon (PAH). 9,10-Dibromoanthracene is often used as an energy acceptor and activator in reactions that produce chemiluminescence.Quality Control of 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Jaradat, Ahmad; Zhang, Chengji; Singh, Sachin Kumar; Ahmed, Junaid; Ahmadiparidari, Alireza; Majidi, Leily; Rastegar, Sina; Hemmat, Zahra; Wang, Shuxi; Ngo, Anh T.; Curtiss, Larry A.; Daly, Matthew; Subramanian, Arunkumar; Salehi-khojin, Amin published an article in 2021. The article was titled 《High Performance Air Breathing Flexible Lithium-Air Battery》, and you may find the article in Small.Quality Control of Indium(III) bromide The information in the text is summarized as follows:

Lithium-oxygen (Li-O2) batteries possess the highest theor. energy d. (3500 Wh kg-1), which makes them attractive candidates for modern electronics and transportation applications. In this work, an inexpensive, flexible, and wearable Li-O2 battery based on the bifunctional redox mediator of InBr3, MoS2 cathode catalyst, and Fomblin-based oxygen permeable membrane that enable long-cycle-life operation of the battery in pure oxygen, dry air, and ambient air is designed, fabricated, and tested. The battery operates in ambient air with an open system air-breathing architecture and exhibits excellent cycling up to 240 at the high c.d. of 1 A g-1 with a relative humidity of 75%. The electrochem. performance of the battery including deep-discharge capacity, and rate capability remains almost identical after 1000 cycle in a bending fatigue test. This finding opens a new direction for utilizing high performance Li-O2 batteries for applications in the field of flexible and wearable electronics. The results came from multiple reactions, including the reaction of Indium(III) bromide(cas: 13465-09-3Quality Control of Indium(III) bromide)

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.Quality Control of Indium(III) bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Majidi, Leily; Ahmadiparidari, Alireza; Shan, Nannan; Kumar Singh, Sachin; Zhang, Chengji; Huang, Zhehao; Rastegar, Sina; Kumar, Khagesh; Hemmat, Zahra; Ngo, Anh T.; Zapol, Peter; Cabana, Jordi; Subramanian, Arunkumar; Curtiss, Larry A.; Salehi-Khojin, Amin published an article in Small. The title of the article was 《Nanostructured Conductive Metal Organic Frameworks for Sustainable Low Charge Overpotentials in Li-Air Batteries》.Application of 13465-09-3 The author mentioned the following in the article:

Lithium-oxygen batteries are among the most attractive alternatives for future electrified transportation. However, their practical application is hindered by many obstacles. Due to the insulating nature of Li2O2 product and the slow kinetics of reactions, attaining sustainable low charge overpotentials at high rates becomes a challenge resulting in the battery′s early failure and low round trip efficiency. Herein, outstanding characteristics are discovered of a conductive metal organic framework (c-MOF) that promotes the growth of nanocrystalline Li2O2 with amorphous regions. This provides a platform for the continuous growth of Li2O2 units away from framework, enabling a fast discharge at high current rates. Moreover, the Li2O2 structure works in synergy with the redox mediator (RM). The conductivity of the amorphous regions of the Li2O2 allows the RM to act directly on the Li2O2 surface instead of catalyst edges and then transport through the electrolyte to the Li2O2 surface. This direct charge transfer enables a small charge potential of <3.7 V under high current densities (1-2 A g-1) sustained for a long cycle life (100-300 cycles) for large capacities (1000-2000 mAh g-1). These results open a new direction for utilizing c-MOFs towards advanced energy storage systems. In addition to this study using Indium(III) bromide, there are many other studies that have used Indium(III) bromide(cas: 13465-09-3Application of 13465-09-3) was used in this study.

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.Application of 13465-09-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Chen, Si; Behera, Nibedita; Yang, Chao; Dong, Qiubing; Zheng, Baishu; Li, Yingying; Tang, Qi; Wang, Zhaoxu; Wang, Yanqing; Duan, Jingui published an article in 2021. The article was titled 《A chemically stable nanoporous coordination polymer with fixed and free Cu2+ ions for boosted C2H2/CO2 separation》, and you may find the article in Nano Research.Recommanded Product: 6825-20-3 The information in the text is summarized as follows:

Safely and highly selective acetylene (C2H2) capture is a great challenge, because of its highly explosive nature, as well as its nearly similar mol. size and b.p. toward the main impurity of carbon dioxide (CO2). Adsorption separation has shown a promising future. Herein, a new nanoporous coordination polymer (PCP) adsorbent with fixed and free Cu ions (termed NTU-66-Cu) was prepared through post-synthetic approach via cation exchanging from the pristine NTU-66, an anionic framework with new 3, 4, 6-c topol. and two kinds of cages. The NTU-66-Cu shows significantly improved C2H2/CO2 selectivity from 6 to 32 (volume/volume: 1/1) or 4 to 42 (volume/volume: 1/4) at low pressure under 298 K, along with enhanced C2H2 capacity (from 89.22 to 111.53 cm3·g-1). More importantly, this observation was further validated by d. functional theory (DFT) calculations and breakthrough experiments under continuous and dynamic conditions. Further, the excellent chem. stability enables this adsorbent to achieve recycle C2H2/CO2 separation without loss of C2H2 capacity. [graphic not available: see fulltext] In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Recommanded Product: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Recommanded Product: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Melin, Lea; Abdullayev, Shuay; Fnaiche, Ahmed; Vu, Victoria; Gonzalez Suarez, Narjara; Zeng, Hong; Szewczyk, Magdalena M.; Li, Fengling; Senisterra, Guillermo; Allali-Hassani, Abdellah; Chau, Irene; Dong, Aiping; Woo, Simon; Annabi, Borhane; Halabelian, Levon; LaPlante, Steven R.; Vedadi, Masoud; Barsyte-Lovejoy, Dalia; Santhakumar, Vijayaratnam; Gagnon, Alexandre published their research in ChemMedChem in 2021. The article was titled 《Development of LM98, a Small-Molecule TEAD Inhibitor Derived from Flufenamic Acid》.HPLC of Formula: 1530-32-1 The article contains the following contents:

The YAP-TEAD transcriptional complex is responsible for the expression of genes that regulate cancer cell growth and proliferation. Dysregulation of the Hippo pathway due to overexpression of TEAD has been reported in a wide range of cancers. Inhibition of TEAD represses the expression of associated genes, demonstrating the value of this transcription factor for the development of novel anti-cancer therapies. We report herein the design, synthesis and biol. evaluation of LM98, a flufenamic acid analog. LM98 shows strong affinity to TEAD, inhibits its autopalmitoylation and reduces the YAP-TEAD transcriptional activity. Binding of LM98 to TEAD was supported by 19F-NMR studies while co-crystallization experiments confirmed that LM98 is anchored within the palmitic acid pocket of TEAD. LM98 reduces the expression of CTGF and Cyr61, inhibits MDA-MB-231 breast cancer cell migration and arrests cell cycling in the S phase during cell division. In the experiment, the researchers used many compounds, for example, Ethyltriphenylphosphonium bromide(cas: 1530-32-1HPLC of Formula: 1530-32-1)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.HPLC of Formula: 1530-32-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Practical Synthesis of the Fluorogenic Enzyme Substrate 4-Methylumbelliferyl α-L-Idopyranosiduronic Acid》 was written by Tian, Jiameng; Ouyang, Wenliang; He, Yanling; Ning, Qianqian; Bai, Jiang; Ding, Haixin; Xiao, Qiang. Product Details of 21085-72-3 And the article was included in Synlett in 2020. The article conveys some information:

A practical and concise synthesis of 4-methylumbelliferyl α-L-idopyranosiduronic acid, a fluorogenic enzyme substrate diagnostic for α-L-iduronidase, was accomplished. It features successive radical bromination and radical reduction of easily accessible Me 4-methylumbelliferyl-2,3,4-tri-O-acetyl-β- D-glucouronate in four steps with 28% overall yield. The experimental part of the paper was very detailed, including the reaction process of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3Product Details of 21085-72-3)

(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.Product Details of 21085-72-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Synthesis and structures of bis(iminophosphorano)methanide chelate complexes with zinc and group 13》 were Zhang, Jin; Ge, Sai; Zhao, Jianguo; Ulhaq, Imran; Ferguson, Michael J.; McDonald, Robert; Ma, Guibin; Cavell, Ronald G.. And the article was published in Polyhedron in 2019. Category: bromides-buliding-blocks The author mentioned the following in the article:

The organolithium bis(iminophosphorano)methandiide dimer [Li2C(Ph2P=NSiMe3)2]2 ([Li2-1]2) reacts with 4 equiv of AlCl3 in THF to generate the novel bimetallic Al carbene complex of [Li(THF)4][{C(Ph2P=NSiMe3)2}Al2Cl5] (1). Several new bis(iminophosphorano)methanide chelate-coordinated complexes of [{CH(Ph2P=NSiMe3)2}AlCl2] (2), [{CH(Ph2P=NSiMe3)2}GaBr2] (3), [{CH(Ph2P=NSiMe3)2}InCl2] (4), and [{CH(Ph2P=NSiMe3)2}InBr2] (5) were synthesized in situ while organolithium bis(iminophosphorano)methandiide ([Li2-1]2) reacts with 2 equiv of metal halides AlCl3, GaBr3 InCl3 and InBr3 resp. in THF. Also, an unexpected complex of [{CH2(Ph2P=NSiMe3)2}ZnCl2] (6) is formed as [Li2-1]2 dimer reacted with 2 equiv of ZnCl2 in situ. All six synthesized complexes (1-6) were isolated in the solid state and were structurally characterized by x-ray diffraction. Complexes containing particular carbene to metal or ionic linking interaction bonds (1-4) were selected and further characterized in detail by DFT calculations using Gaussian03 program. The DFT calculation demonstrates the existence of a carbene-Al σ bond in structure 1 and ionic linkage interaction in structures 2-4. In the experiment, the researchers used Indium(III) bromide(cas: 13465-09-3Category: bromides-buliding-blocks)

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Design and Synthesis of WJ-Phos, and Application in Cu-Catalyzed Enantioselective Boroacylation of 1,1-Disubstituted Allenes》 were Han, Jie; Zhou, Wei; Zhang, Pei-Chao; Wang, Huamin; Zhang, Ronghua; Wu, Hai-Hong; Zhang, Junliang. And the article was published in ACS Catalysis in 2019. Category: bromides-buliding-blocks The author mentioned the following in the article:

The highly enantioselective copper-catalyzed three-component boroacylation of 1,1-disubstituted allenes is reported by using a class of chiral ligands (WJ-Phos), delivering various functionalized organoboron compounds bearing an all-carbon stereocenter in moderate to good yields with high enantioselectivities. WJ-Phos is a ferrocene-derived chiral sulfinamide phosphine ligand and can be easily synthesized in gram-scale from readily available starting materials in short steps. The salient features of this reaction include moderate to good yields, high enantioselectivities, gram-scale synthesis, diverse synthetic transformations, and the development of a new chiral ligand. In the part of experimental materials, we found many familiar compounds, such as Methyltriphenylphosphonium bromide(cas: 1779-49-3Category: bromides-buliding-blocks)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary