Tag: 300-400

Xia, Liwen; Jin, Maolu; Jiao, Yi; Yu, Shouyun published an article in 2022. The article was titled 《Synthesis of C-Alkynyl Glycosides by Photoredox-Catalyzed Reductive Coupling of Alkynyl Bromides with Glycosyl Bromides》, and you may find the article in Organic Letters.Quality Control of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate The information in the text is summarized as follows:

A general, convenient, and highly α stereoselective approach to access C-alkynyl glycosides via the photoredox-catalyzed reductive coupling of alkynyl bromides and glycoside bromides has been developed. Cheap and small-load eosin Y is used as the photocatalyst, and organic base N,N-diisopropylethylamine serves as the reducing reagent. This strategy features readily available starting materials, diverse substrates, mild conditions, and high α stereoselectivity. Moreover, a glycoconjugate peptide could also be achieved using this strategy. After reading the article, we found that the author used (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3Quality Control of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate)

(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.Quality Control of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Huang, Jie; Chen, Ling-Ling; Chen, Zhi-Min published an article in 2022. The article was titled 《Palladium-Catalyzed Three-Component Cross-Coupling of Conjugated Dienes with Indoles Using Ethynylbenziodazolones as Electrophilic Alkynylating Reagents》, and you may find the article in Organic Letters.Synthetic Route of Br3In The information in the text is summarized as follows:

A palladium-catalyzed regioselective 1,2-alkynyl-carbonalization of conjugated dienes with ethynylbenziodazolones (EBZ) and indoles was developed for the first time. Various mols. containing alkenyl, alkynyl and indole groups were readily obtained. Moreover, the resulting products can be applied to various derivatizations. This protocol used EBZ as an electrophilic alkynylating reagent, avoiding the byproduct of dimerization of alkynes. In the experimental materials used by the author, we found Indium(III) bromide(cas: 13465-09-3Synthetic Route of Br3In)

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Synthetic Route of Br3In

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yang, Yisi; Li, Libo; Lin, Rui-Biao; Ye, Yingxiang; Yao, Zizhu; Yang, Ling; Xiang, Fahui; Chen, Shimin; Zhang, Zhangjing; Xiang, Shengchang; Chen, Banglin published an article in 2021. The article was titled 《Ethylene/ethane separation in a stable hydrogen-bonded organic framework through a gating mechanism》, and you may find the article in Nature Chemistry.Electric Literature of C12H7Br2N The information in the text is summarized as follows:

Porous materials are very promising for the development of cost- and energy-efficient separation processes, such as for the purification of ethylene from ethylene/ethane mixture-an important but currently challenging industrial process. Here we report a microporous hydrogen-bonded organic framework that takes up ethylene with very good selectivity over ethane through a gating mechanism. The material consists of tetracyano-bicarbazole building blocks held together through intermol. CN···H-C hydrogen bonding interactions, and forms as a threefold-interpenetrated framework with pores of suitable size for the selective capture of ethylene. The hydrogen-bonded organic framework exhibits a gating mechanism in which the threshold pressure required for guest uptake varies with the temperature Ethylene/ethane separation is validated by breakthrough experiments with high purity of ethylene (99.1%) at 333 K. Hydrogen-bonded organic frameworks are usually not robust, yet this material was stable under harsh conditions, including exposure to strong acidity, basicity and a variety of highly polar solvents. In addition to this study using 3,6-Dibromo-9H-carbazole, there are many other studies that have used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Electric Literature of C12H7Br2N) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Electric Literature of C12H7Br2N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Li, Cai-Yi; Ma, Yue; Lei, Zhi-Wei; Hu, Xiang-Guo published their research in Organic Letters in 2021. The article was titled 《Glycosyl-Radical-Based Synthesis of C-Alkyl Glycosides via Photo-mediated Defluorinative gem-Difluoro-allylation》.COA of Formula: C13H17BrO9 The article contains the following contents:

We have developed a stereoselective, glycosyl radical-based method for the synthesis of C-alkyl glycosides via a photo-mediated defluorinative gem-difluoroallylation reaction. We demonstrate for the first time that glycosyl radicals, generated from glycosyl bromides, can readily participate in a photo-mediated radical polar crossover process, affording a diverse array of gem-difluoro-alkene containing C-glycosides. Notable features of this method include scalability, mild conditions, broad substrate scope, and suitability for the late-stage modification of complex mols. In the experiment, the researchers used many compounds, for example, (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3COA of Formula: C13H17BrO9)

(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.COA of Formula: C13H17BrO9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zhang, Yulong; He, Jun; Song, Peihong; Wang, You; Zhu, Shaolin published their research in CCS Chemistry in 2021. The article was titled 《Ligand-enabled NiH-catalyzed migratory hydroamination: chain walking as a strategy for regiodivergent/regioconvergent remote sp3C-H amination》.Product Details of 1530-32-1 The article contains the following contents:

A nondirected, remote sp3C-H amination process with predictable and switchable regioselectivity was reported. This reaction used a nickel hydride-catalyzed remote relay hydroamination strategy in which an aliphatic amino group was installed at a position far from the original C=C bond present in all unsaturated hydrocarbon substrates. Depending on the choice of ligand, either terminal or benzylic functionalization products were obtained with excellent levels of regioselectivity. It was shown that an alkyl bromide could also be used as an olefin precursor when using Mn0 as a reductant. The utility of this transformation was further highlighted by the regioconvergent migratory hydroamination of isomeric mixtures of olefins forming single isomers of value-added benzylic or linear amines. The experimental part of the paper was very detailed, including the reaction process of Ethyltriphenylphosphonium bromide(cas: 1530-32-1Product Details of 1530-32-1)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.Product Details of 1530-32-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Enhancement of photoluminescence quantum yield and stability in CsPbBr3 perovskite quantum dots by trivalent doping》 was written by Jung, Sujeong; Kim, Jae Ho; Choi, Jin Woo; Kang, Jae-Wook; Jin, Sung-Ho; Kang, Youngho; Song, Myungkwan. Computed Properties of Br3In And the article was included in Nanomaterials in 2020. The article conveys some information:

We determine the influence of substitutional defects on perovskite quantum dots through exptl. and theor. investigations. Substitutional defects were introduced by trivalent dopants (In, Sb, and Bi) in CsPbBr3 by ligand-assisted reprecipitation We show that the photoluminescence (PL) emission peak shifts toward shorter wavelengths when doping concentrations are increased. Trivalent metal-doped CsPbBr3 enhanced the PL quantum yield (~10%) and air stability (over 10 days). Our findings provide new insights into the influence of substitutional defects on substituted CsPbBr3 that underpin their phys. properties. After reading the article, we found that the author used Indium(III) bromide(cas: 13465-09-3Computed Properties of Br3In)

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.Computed Properties of Br3In

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Dalton Transactions included an article by Xu, Ning; Zhang, Qinghua; Zhang, Guoan. Recommanded Product: 6825-20-3. The article was titled 《A carbazole-functionalized metal-organic framework for efficient detection of antibiotics, pesticides and nitroaromatic compounds》. The information in the text is summarized as follows:

Organic pollutants, such as antibiotics, pesticides, and nitroarom. compounds (NACs), have posed a great threat to human health and sustainable development. Therefore, the detection of these organic pollutants is of great importance but challenging. The authors synthesized a rigid conjugated tricarboxylic acid ligand 4,4′-(9-(4′-carboxy-[1,1′-biphenyl]-4-yl)-9H-carbazole-3,6-diyl)dibenzoic acid (H3CBCD), and employed this ligand to react with Cd(II) ions to construct a Cd-LMOF, namely [Cd3(CBCD)2(DMA)4(H2O)2]·10DMA (Cd-CBCD). Cd-CBCD features a three-dimensional (3D) supramol. framework based on two-dimensional (2D) layer structures through π···π stacking interactions. The fluorescence sensing measurements demonstrate that Cd-CBCD can detect nitrofurans (NFs), 4-nitroaniline (4-NA) and 2,6-dichloro-4-nitroaniline (DCN) with high selectivity and sensitivity. This work represents the first carbazole-functionalized metal-organic framework as a fluorescent sensor for the highly efficient detection of antibiotics, pesticides and nitroarom. compounds The experimental process involved the reaction of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Recommanded Product: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Recommanded Product: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,ChemistrySelect included an article by Shao, Huibin; Wang, Xiaopei; Wang, Yanyan; Yue, Yuanyuan; Wang, Ke; Tang, Qinghu; Zhuo, Kelei; Liu, Jianming. HPLC of Formula: 6825-20-3. The article was titled 《BF3·Et2O-Promoted Aerobic Bromination of Heteroarenes with LiBr as the Bromination Sources》. The information in the text is summarized as follows:

Aromatic bromination of heteroarenes, e.g., 10H-phenothiazine has been accomplished by using readily available LiBr with the aid of BF3·Et2O under mild aerobic conditions. The broad substrates scope of the reaction is compatible with the optimized condition, and excellent functional-group is well tolerated in this transformation. The gram-scale preparation of aromatic bromides RBr (R = 3-methyl-5-phenyl-1H-pyrazol-4-yl, 9H-carbazol-3-yl) exhibits good reaction efficiency. Meanwhile, the dibromination of heteroarenes I (R1 = H, CH3; R2 = H, OCH3, Cl) delivers the polybromo-aromatic compounds II in good yields. The experimental process involved the reaction of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3HPLC of Formula: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent. And it has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.HPLC of Formula: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2018,Kita, Yuji; Yata, Tetsuji; Nishimoto, Yoshihiro; Chiba, Kouji; Yasuda, Makoto published 《Selective oxymetalation of terminal alkynes via 6-endo cyclization: mechanistic investigation and application to the efficient synthesis of 4-substituted isocoumarins》.Chemical Science published the findings.Synthetic Route of Br3In The information in the text is summarized as follows:

Herein, a novel cyclic oxymetalation of 2-alkynylbenzoate with indium or gallium salts that proceeds with an unusual regioselectivity to give isocoumarins bearing a carbon-metal bond at the 4-position was reported. Indium and gallium salts showed high performance in the selective 6-endo cyclization of terminal alkynes while boron or other metals such as Al, Au, and Ag caused 5-exo cyclization or decomposition of terminal alkynes, resp. The metalated isocoumarin and its reaction intermediate were unambiguously identified by X-ray crystallog. anal. The theor. calculation of potential energy profiles showed that oxyindation could proceed via 6-endo cyclization under thermodn. control while previously reported oxyboration would give a 5-membered ring under kinetic control. The investigation of electrostatic potential maps suggested that the differences in the at. characters of indium, boron and their ligands would contribute to such a regioselective switch. and metalated isocoumarins were applied to organic synthetic reactions. The halogenation of metalated isocoumarins proceeded to afford 4-halogenated isocoumarins bearing various functional groups and palladium-catalyzed cross coupling of organometallic species with organic halides gave various 4-substituted isocoumarins. A formal total synthesis of oosponol, which exhibits strong antifungal activity, was accomplished. In addition to this study using Indium(III) bromide, there are many other studies that have used Indium(III) bromide(cas: 13465-09-3Synthetic Route of Br3In) was used in this study.

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Synthetic Route of Br3In

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Grajewski, Jakub; Zgorzelak, Mikolaj; Janiak, Agnieszka; Taras-Goslinska, Katarzyna published an article in ChemPlusChem. The title of the article was 《Controlled, Sunlight-Driven Reversible Cycloaddition of Multiple Singlet Oxygen Molecules to Anthracene-Containing Trianglimine Macrocycles》.Quality Control of 9,10-Dibromoanthracene The author mentioned the following in the article:

Controlled release of singlet oxygen is of interest not only to chemists, but also to biologists and medics involved in cancer therapy. Two chiral polyaza macrocyclic compounds and their corresponding endoperoxides have been synthesized. These peroxides exhibit high temperature stability, up to 80°C. Detailed studies on their structure, including X-ray anal. as well as NMR, UV-VIS ECD spectroscopy and theor. calculations, combined with photochem. measurements indicate that their high stability is related to the arrangement of oxygen atoms in a conformationally stable macrocyclic ring. Despite the change of carbon hybridization from sp2 to sp3 at the 9 and 10 positions of the anthracene units, the macrocyclic skeleton of the obtained compounds does not change its conformation. The obtained endoperoxides can be formed and release singlet oxygen by irradiation with UV light of 365 and 275 nm, resp. Release of the oxygen does not degrade the macrocyclic structure. The results came from multiple reactions, including the reaction of 9,10-Dibromoanthracene(cas: 523-27-3Quality Control of 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) is a dibrominated polycyclic aromatic hydrocarbon (PAH). 9,10-Dibromoanthracene is often used as an energy acceptor and activator in reactions that produce chemiluminescence.Quality Control of 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary