Tag: 300-400

The author of 《Enantioselective Cross-Exchange between C-I and C-C σ Bonds》 were Sun, Yu-Li; Wang, Xing-Ben; Sun, Feng-Na; Chen, Qian-Qian; Cao, Jian; Xu, Zheng; Xu, Li-Wen. And the article was published in Angewandte Chemie, International Edition in 2019. Computed Properties of C19H18BrP The author mentioned the following in the article:

A palladium-catalyzed enantioselective intramol. σ-bond cross-exchange between C-I and C-C bonds is realized, providing chiral indanones bearing an alkyl iodide group and an all-carbon quaternary stereocenter, e.g., I. Pd/TADDOL-derived phosphoramidite is found to be an efficient catalytic system for both C-C bond cleavage and alkyl iodide reductive elimination. In addition to aryl iodides, aryl bromides can also be used for this transformation in the presence of KI. D.-functional theory (DFT) calculation studies support the ring-opening of cyclobutanones, e.g., II, occurring through an oxidative addition/reductive elimination process involving PdIV species. In the experiment, the researchers used many compounds, for example, Methyltriphenylphosphonium bromide(cas: 1779-49-3Computed Properties of C19H18BrP)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Computed Properties of C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

The author of 《Physical properties of ethylene glycol-based deep eutectic solvents》 were Ibrahim, Rusul Khaleel; Hayyan, Maan; AlSaadi, Mohammed Abdulhakim; Ibrahim, Shaliza; Hayyan, Adeeb; Hashim, Mohd Ali. And the article was published in Journal of Molecular Liquids in 2019. Quality Control of Methyltriphenylphosphonium bromide The author mentioned the following in the article:

Deep eutectic solvents (DESs) have been widely recognized as ionic liquids (ILs) analogs due to their low production cost and superior favorable properties over conventional ILs. Studying the phys. properties of these solvents will contribute to design processes involving DESs. In this study, five DESs have been successfully prepared using ethylene glycol (EG) as hydrogen bond donor (HBD) with N,N-diethylethanolammonium chloride (DAC), benzyltriphenylphosphonium chloride (BTPC), choline chloride (ChCl), methyltriphenylphosphonium bromide (MTPB) and tetra-n-butylammonium bromide (TBAB) as salts. The f.p. of each of the five studied DESs was measured using Differential Scanning Calorimetry (DSC) and the DES functional groups were identified using the Fourier transform IR (FTIR) spectroscopy. Moreover, the viscosity, d., elec. conductivity and surface tension were measured at a temperature range of 293.15-353.15 K and they were highly affected by the variation of the temperature It is worth mentioning that the studied DESs showed many phys. characteristics similar to that of ILs, which boost their possibilities to be employed in interdisciplinary domains.Methyltriphenylphosphonium bromide(cas: 1779-49-3Quality Control of Methyltriphenylphosphonium bromide) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Quality Control of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2018,Alonso-Maranon, Lorena; Sarandeses, Luis A.; Martinez, M. Montserrat; Perez Sestelo, Jose published 《Synthesis of fused chromenes by the indium(III)-catalyzed cascade hydroarylation/cycloisomerization reactions of polyyne-type aryl propargyl ethers》.Organic Chemistry Frontiers published the findings.Product Details of 13465-09-3 The information in the text is summarized as follows:

Fused 2H-chromenes were prepared by the cascade hydroarylation/cycloisomerization reactions of polyyne-type aryl propargyl ethers using indium(III) catalysis. The transformation proceeded with 6-endo-dig regioselectivity using InBr3 (5 mol%). The method was extended to triynes allowing the formation of three bonds in one pot. Indium(III) also catalyzed the hydroamination/hydroarylation cascade reaction of o-aryldiynyl anilines to form fused carbazoles. In the experimental materials used by the author, we found Indium(III) bromide(cas: 13465-09-3Product Details of 13465-09-3)

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Product Details of 13465-09-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Ahmed, Mostafa; Kotp, Mohammed G.; Mansoure, Tharwat Hassan; Lee, Rong-Ho; Kuo, Shiao-Wei; El-Mahdy, Ahmed F. M. published an article in Microporous and Mesoporous Materials. The title of the article was 《Ultrastable carbazole-tethered conjugated microporous polymers for high-performance energy storage》.Application of 6825-20-3 The author mentioned the following in the article:

Conjugated microporous polymers (CMPs) have considered as organic porous polymers featuring combination of p-conjugated skeletons with permanent micro-porosity. In the present study, we report the synthesis of carbazole-tethered conjugated microporous polymers, BC-Py-CMP and BC-BF-CMP, resp., through the Suzuki-Miyaura coupling polymerization of the novel 3,3′,6,6′-tetraboronic-pinacolate-9,9′-bicarbazole (BC-4Bpin) with 1,3,6,8-tetrabromopyrene (Py-4Br) and 3,3′,6,6′-tetrabromo-9,9′-bifluorenylidene (BF-4Br). These CMPs exhibited extraordinary thermal stabilities (up to ca. 694 and 569 °C) and high surface areas (up to ca. 1030 m2 g-1). Moreover, the as-prepared BC-BF-CMP exhibited a high specific capacitance of 260 F g-1 at 0.5 A g-1 and showed outstanding cycling stability, having 89.60% capacitance retention of its authentic capacitance over 6000 cycles. The excellent electrochem. capacitances of the BC-BF-CMP were presumably due to the 9,9′-BF could easily accept one electron, causing the reduced form acquiring greater aromaticity by meeting Huckel′s requirements, as a result improving the electron transporting properties. Such CMPs tend to have tremendous potential to be used as a high-performance supercapacitors in energy storage systems. In addition to this study using 3,6-Dibromo-9H-carbazole, there are many other studies that have used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Application of 6825-20-3) was used in this study.

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Application of 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yao, Wang; Zhao, Gaoyuan; Wu, Yue; Zhou, Lin; Mukherjee, Upasana; Liu, Peng; Ngai, Ming-Yu published an article in 2022. The article was titled 《Excited-State Palladium-Catalyzed Radical Migratory Mizoroki-Heck Reaction Enables C2-Alkenylation of Carbohydrates》, and you may find the article in Journal of the American Chemical Society.Category: bromides-buliding-blocks The information in the text is summarized as follows:

Excited-state palladium catalysis has emerged as a promising strategy for developing novel and valuable reactions. Herein, we report the first excited-state Pd-catalyzed 1,2-radical migratory Mizoroki-Heck reaction that enables C2-alkenylation of carbohydrates using readily available 1-bromosugars and alkenes. The reaction tolerates a wide variety of functional groups and complex mol. architectures, including derivatives of natural products and marketed drugs. Preliminary mechanistic studies and DFT calculations suggest the involvement of visible-light-induced photoexcitation of Pd species, 1,2-spin-centered-shift (SCS) process, and Heck-type cross-coupling reaction. The reaction expands the reactivity profile of excited-state Pd catalysis and provides a streamlined protocol for the preparation of a wide variety of C2-alkenylated carbohydrate mimetics to aid the discovery and development of new therapeutics, agrochems., and materials. In addition to this study using (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate, there are many other studies that have used (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3Category: bromides-buliding-blocks) was used in this study.

(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Gao, Jihui; Jiao, Mingdong; Ni, Jie; Yu, Rongrong; Cheng, Gui-Juan; Fang, Xianjie published an article in 2021. The article was titled 《Nickel-Catalyzed Migratory Hydrocyanation of Internal Alkenes: Unexpected Diastereomeric-Ligand-Controlled Regiodivergence》, and you may find the article in Angewandte Chemie, International Edition.Synthetic Route of C20H20BrP The information in the text is summarized as follows:

A regiodivergent nickel-catalyzed hydrocyanation of a broad range of internal alkenes involving a chain-walking process is reported. When appropriate diastereomeric biaryl diphosphite ligands are applied, the same starting materials can be converted to either linear or branched nitriles with good yields and high regioselectivities. DFT calculations suggested that the catalyst architecture determines the regioselectivity by modulating electronic and steric interactions. In addition, moderate enantioselectivities were observed when branched nitriles were produced. After reading the article, we found that the author used Ethyltriphenylphosphonium bromide(cas: 1530-32-1Synthetic Route of C20H20BrP)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.Synthetic Route of C20H20BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Guo, Weisi; Wang, Qian; Zhu, Jieping published an article in 2021. The article was titled 《Selective 1,2-Aminoisothiocyanation of 1,3-Dienes Under Visible-Light Photoredox Catalysis》, and you may find the article in Angewandte Chemie, International Edition.HPLC of Formula: 1779-49-3 The information in the text is summarized as follows:

Selective three-component 1,2-diamination of 1,3-dienes with concurrent introduction of two orthogonally protected amino groups remains unknown despite its significant synthetic potential. We report herein that reaction of conjugated dienes such as (E)-PhCH:CHCH:CH2 with N-aminopyridinium salts such as I·BF4- (Ts = 4-MeC6H4SO2) and TMSNCS affords 1,2-aminoisothiocyanation products such as II in a highly chemo- and regio-selective manner under mild photoredox catalytic conditions. Mechanistic studies indicate that the facile isomerization of allyl thiocyanates to allyl isothiocyanates under photocatalytic conditions is responsible for the selective formation of the observed products. The mild isomerization protocol is expected to find applications in the synthesis of allyl isothiocyanates in a broad sense. In the part of experimental materials, we found many familiar compounds, such as Methyltriphenylphosphonium bromide(cas: 1779-49-3HPLC of Formula: 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.HPLC of Formula: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yu, You-Jie; Zhang, Feng-Lian; Peng, Tian-Yu; Wang, Chang-Ling; Cheng, Jie; Chen, Chen; Houk, Kendall N.; Wang, Yi-Feng published their research in Science (Washington, DC, United States) in 2021. The article was titled 《Sequential C-F bond functionalizations of trifluoroacetamides and acetates via spin-center shifts》.Electric Literature of C19H18BrP The article contains the following contents:

Defluorinative functionalization of readily accessible trifluoromethyl groups constitutes an economical route to partially fluorinated mols. However, the controllable replacement of one or two fluorine atoms while maintaining high chemoselectivity remains a formidable challenge. Here we describe a general strategy for sequential carbon-fluorine (C-F) bond functionalizations of trifluoroacetamides and trifluoroacetates. The reaction begins with the activation of a carbonyl oxygen atom by a 4-dimethylaminopyridine-boryl radical, followed by a spin-center shift to trigger the C-F bond scission. A chemoselectivity-controllable two-stage process enables sequential generation of difluoro- and monofluoroalkyl radicals, which are selectively functionalized with different radical traps to afford diverse fluorinated products. The reaction mechanism and the origin of chemoselectivity were established by exptl. and computational approaches. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3Electric Literature of C19H18BrP)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Electric Literature of C19H18BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Baalbaki, Hassan A.; Roshandel, Hootan; Hein, Jason E.; Mehrkhodavandi, Parisa published their research in Catalysis Science & Technology in 2021. The article was titled 《Conversion of dilute CO2 to cyclic carbonates at sub-atmospheric pressures by a simple indium catalyst》.Related Products of 13465-09-3 The article contains the following contents:

The transformation of CO2 to value added commodity chems. presents an impactful strategy to obtain products that are less dependent on fossil fuels. In this study, indium tribromide (InBr3) mixed with tetrabutylammonium bromide (NBu4Br) co-catalyst has been identified as a simple, highly efficient catalyst for the synthesis of cyclic carbonates from epoxides and CO2 at sub-atm. pressures, room temperature, and under solvent-free conditions. The InBr3/NBu4Br catalytic system is tolerant toward different functional groups with high conversions and >99% selectivity for cyclic carbonate without resorting to high pressures and temperatures Moreover, a combination of in situ IR, NMR spectroscopy, and substrate labeling experiments enabled the proof of key catalytic steps and detection of reaction intermediates to elucidate the reaction mechanism. This technol. represents a potential scalable system for the utilization of waste CO2. After reading the article, we found that the author used Indium(III) bromide(cas: 13465-09-3Related Products of 13465-09-3)

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.Related Products of 13465-09-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《A Green-Emission Metal-Organic Framework-Based Nanoprobe for Imaging Dual Tumor Biomarkers in Living Cells》 was written by Kong, Xiang-Jing; Ji, Xiaoting; He, Tao; Xie, Lin-Hua; Zhang, Yong-Zheng; Lv, Haoyuan; Ding, Caifeng; Li, Jian-Rong. Safety of 3,6-Dibromo-9H-carbazole And the article was included in ACS Applied Materials & Interfaces in 2020. The article conveys some information:

The modular nature of metal-organic frameworks (MOFs) permits their tunable structure and function for target application, such as in biomedicine. Herein, a green-emission Zr(IV)-MOF (BUT-88) was constructed from a customized luminescent carbazolyl ligand. BUT-88 represents the first bcu-type MOF with both organic linker and metal node in eight connections and shows medium-sized pores, rich accessible linking sites, and good water stability and biocompatibility. In virtue of these merits, BUT-88 was then fabricated into a MOF-based fluorescent nanoprobe, drDNA-BUT-88. Using it, the live-cell imaging of dual tumor biomarkers was achieved for the first time upon a MOF-based probe, offering enhanced detection precision in early cancer diagnosis. Particularly, the probe showed efficient ratiometric fluorescent sensing toward the cytoplasmic biomarker microRNA-21, further improving the detection accuracy at the cellular level. The elaborate combination of MOF engineering and the fluorescent detection technique has contributed a facile biosensing platform, unlocking more possibilities of MOF chem. The results came from multiple reactions, including the reaction of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Safety of 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used as a reagent in the synthesis of P7C3-A20 which is a potent neuroprotective agent.Safety of 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary