Tag: 300-400

The author of 《Cationic Co(I)-Intermediates for Hydrofunctionalization Reactions: Regio- and Enantioselective Cobalt-Catalyzed 1,2-Hydroboration of 1,3-Dienes》 were Duvvuri, Krishnaja; Dewese, Kendra R.; Parsutkar, Mahesh M.; Jing, Stanley M.; Mehta, Milauni M.; Gallucci, Judith C.; RajanBabu, T. V.. And the article was published in Journal of the American Chemical Society in 2019. Product Details of 1779-49-3 The author mentioned the following in the article:

Much of the recent work on catalytic hydroboration of alkenes has focused on simple alkenes and styrene derivatives with few examples of reactions of 1,3-dienes, which are reported to undergo mostly 1,4-additions to give allylic boronates. Reduced Co catalysts generated from 1,n-bis-diphenylphosphinoalkane complexes [Ph2P-(CH2)n-PPh2]CoX2; (n = 1-5) or from (2-oxazolinyl)phenyldiarylphosphine complexes [(G-PHOX)CoX2] (G = 4-substituent on oxazoline ring) effect selective 1,2-, 1,4-, or 4,3-additions of pinacolborane (HBPin) to a variety of 1,3-dienes depending on the ligands chosen. Conditions optimize the 1,2-additions The reactive catalysts can be generated from the Co(II)-complexes using trimethylaluminum, Me aluminoxane, or activated Zn in the presence of Na tetrakis[(3,5-trifluoromethyl)phenyl]borate (NaBARF). The complex, (dppp)CoCl2, gives the best results (ratio of 1,2- to 1,4-addition >95:5) for a variety of linear terminal 1,3-dienes and 2-substituted 1,3-dienes. The [(PHOX)CoX2] (X = Cl, Br) complexes give mostly 1,4-addition with linear unsubstituted 1,3-dienes, but, surprisingly, selective 1,2-additions with 2-substituted or 2,3-disubstituted 1,3-dienes. Isolated and fully characterized (x-ray crystallog.) Co(I)-complexes, (dppp)3Co2Cl2 and [(S,S)-BDPP]3Co2Cl2, do not catalyze the reaction unless activated by a Lewis acid or NaBARF, suggesting a key role for a cationic Co(I) species in the catalytic cycle. Regio- and enantioselective 1,2-hydroborations of 2-substituted 1,3-dienes are best accomplished using a catalyst prepared via activation of a chiral phosphinooxazoline-Co(II) complex with Zn and NaBARF. A number of common functional groups, among them, -OBn, -OTBS, -OTs, N-phthalimido- groups, are tolerated, and er’s > 95:5 were obtained for several dienes including 1-alkenylcycloalk-1-enes. This operationally simple reaction expands the realm of asym. hydroboration to provide direct access to a number of nearly enantiopure homoallylic boronates, which are not readily accessible by current methods. The resulting boronates were converted into the corresponding alcs., K trifluororoborate salts, N-BOC amines, and aryl derivatives by C-BPin to C-aryl transformation. The results came from multiple reactions, including the reaction of Methyltriphenylphosphonium bromide(cas: 1779-49-3Product Details of 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Product Details of 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bai, Hongyuan; Han, Li; Li, Wei; Li, Chao; Zhang, Songbo; Wang, Xuefei; Yin, Yu; Yan, Hong; Ma, Hongwei published their research in Macromolecules (Washington, DC, United States) in 2021. The article was titled 《C5 and C6 Polymerizations by Anion Migrated Ring-Opening of 1-Cyclopropylvinylbenzene and 1-Cyclobutylvinylbenzene》.Category: bromides-buliding-blocks The article contains the following contents:

As an emerging method, anion migrated ring-opening polymerization (AMROP) can effectively regulate the carbon skeletons of polymer backbones with specific vinyl monomers. As reported here, polymers with C5 and C6 skeletons were synthesized by AMROP of 1-cyclopropylvinylbenzene (CPVB) and 1-cyclobutylvinylbenzene (CBVB). Moreover, C4 polymerization of 1-phenyl-1,3-butadiene (1-PB) was also conducted (in a general anionic polymerization process) for comparison with C5 and C6 polymerizations Among the three base polymers prepared with the C4, C5, and C6 polymerizations, PCBVB exhibited the most flexible carbon skeleton structure and the lowest glass transition temperature (Tg = -18.8°C). Then, the resultant base polymers with different carbon skeletons were hydrogenated and cyclized. The hydrogenation of P(1-PB), PCPVB, and PCBVB resulted in the formation of products with unique alternating styrene/ethylene (alt-SE), periodic styrene/ethylene/methylene (pd-SEM), and periodic styrene/ethylene/ethylene (pd-SEE) structures. Moreover, pd-SEM and pd-SEE can be considered as sequence-defined template polymers, and these structures cannot be synthesized through general copolymerization of styrene and ethylene. Owing to the specific carbon skeletons exhibited in alt-SE, pd-SEM, and pd-SEE, their Tg values showed significant differences (24.6, 10.9, and -6.0°C, resp.). Addnl., the specific carbon skeletons of the base polymers resulted in the formation of cyclized polymers with different annular substituents. Moreover, diverse annular substitutes endowed the cyclized polymers with prominent thermal resistance and luminescence properties. Through the above investigations, it is clearly demonstrated that small changes in carbon skeleton structure can remarkably affect the polymer properties. Moreover, AMROP provides a new strategy to design novel polymers with C5 and C6 skeleton structures.Methyltriphenylphosphonium bromide(cas: 1779-49-3Category: bromides-buliding-blocks) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is used for methylenation through the Wittig reaction. It is utilized in the synthesis of an enyne and 9-isopropenyl -phenanthrene by using sodium amide as reagent. Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Thermally Controlled On/Off Switch in a Living Anionic Polymerization of 1-Cyclopropylvinylbenzene with an Anion Migrated Ring-Opening Mechanism》 was written by Bai, Hongyuan; Leng, Xuefei; Han, Li; Yang, Lincan; Li, Chao; Shen, Heyu; Lei, Lan; Zhang, Songbo; Wang, Xuefei; Ma, Hongwei. HPLC of Formula: 1779-49-3 And the article was included in Macromolecules (Washington, DC, United States) in 2020. The article conveys some information:

A reversible on/off switch to control chain growth in a living anionic polymerization is a meaningful challenge for its profound potential in both polymerization mechanisms and the preparation of advanced materials. Herein, we report a thermally controlled on/off switch for chain propagation in an anionic polymerization that is realized with a 1-cyclopropylvinylbenzene (CPVB) monomer. Interestingly, the specific ring-opening manner and thermal sensitivity are shown in the addition reaction of CPVB with the initiator or living chains. The ring opening of the cyclopropyl group in CPVB is observed to be a possible anion migrated ring-opening mechanism in the addition reactions. Addnl., the polymerization of CPVB occurs only at high temperature, and the chain growth constant kCC is near 0 at 20°C, 0.0039 (L/mol)1/2 min-1 at 50°C, and 0.016 (L/mol)1/2 min-1 at 60°C. Thus, based on its unique characteristics, an ingenious design of “”heat (60°C)-cool (20°C)”” cycles is employed to achieve a thermally controlled on/off switch for chain growth in an anionic polymerization It is expected that this finding can provide new insights into both controlling the monomer or multiblock sequence and raise a novel technique to stage control the chain growth with temperatures in living anionic polymerization In addition to this study using Methyltriphenylphosphonium bromide, there are many other studies that have used Methyltriphenylphosphonium bromide(cas: 1779-49-3HPLC of Formula: 1779-49-3) was used in this study.

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.HPLC of Formula: 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Synthesis and Cross-Linking of a Benzoxazine-Containing Anthracene Moiety: Thermally Stable Photoluminescent Benzoxazine Resin》 was published in Macromolecules (Washington, DC, United States) in 2020. These research results belong to Goto, Masahide; Yajima, Tatsuo; Minami, Masaki; Sogawa, Hiromitsu; Sanda, Fumio. SDS of cas: 523-27-3 The article mentions the following:

A novel benzoxazine derivative, 9,10-bis(6-ethynyl-3-phenyl-3,4-dihydro-1,3-benzoxazine)anthracene (1a), was synthesized by the Sonogashira-Hagihara coupling reaction of 9,10-dibromoanthracene and 6-ethynyl-3-phenyl-3,4-dihydro-1,3-benzoxazine. A CH2Cl2 solution of 1a luminesced with a high quantum yield (Φ = 81%). Compound 1a afforded solvent-insoluble cross-linked polybenzoxazine 1b by the bulk polymerization at 250°C. Solution polymerization of a dilute solution of 1a at 200°C afforded solvent-soluble samples, accompanied by a decrease of photoluminescence intensity. The weight loss values of 1a and 1b were 81 and 87%, resp., under nitrogen at 500°C. We believe that the present study will lead to thermally stable curing resins whose degree of curing can be estimated with the naked eye by observing the decrease of photoluminescence. In the experiment, the researchers used many compounds, for example, 9,10-Dibromoanthracene(cas: 523-27-3SDS of cas: 523-27-3)

9,10-Dibromoanthracene(cas: 523-27-3) is synthesized by the bromination of anthracene. The bromination reaction is carried out at room temperature using carbon tetrachloride as a solvent. Using 80-85% anthracene as raw material, adding bromine to react for half an hour, the yield is 83-88%.SDS of cas: 523-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Organic Chemistry Frontiers included an article by Koffi Teki, Dindet Steve-Evanes; Bil, Abed; Moreau, Vincent; Chagnault, Vincent; Fante, Bamba; Adjou, Ane; Kovensky, Jose. COA of Formula: C13H17BrO9. The article was titled 《Synthesis of multivalent S-glycoside analogs of a heparan sulfate sequence》. The information in the text is summarized as follows:

Glycosaminoglycans (GAGs) are involved in the regulation of a large number of biol. processes such as inflammation, cell signaling, angiogenesis, viral infection and coagulation. Unlike mols. isolated from tissues, pure mols., derived from organic synthesis, can prevent side effects and are very useful tools for understanding the structure-activity relationships of many biol. and pharmacol. activities. In our research group, we focus particularly on the synthesis of multivalent thioglycoside analogs. In this article, we report on the synthesis of new glycoclusters with thiodisaccharide units, S-analogs of heparan sulfate. The thiodisaccharide analog was obtained by nucleophilic displacement of a 4-triflate galactoside derivative, by an anomeric thiol of a glucuronic acid precursor. After modifying the aglycon part to introduce an azide, the thiodisaccharide was coupled to maltotriose scaffolds carrying one, two or three propargyl groups by CuAAC. After reading the article, we found that the author used (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3COA of Formula: C13H17BrO9)

(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.COA of Formula: C13H17BrO9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Total Synthesis of (+)-Oxo-tomaymycin》 was written by Benedetti, Francoise; Perrin, Marc-Antoine; Bosc, Sebastien; Chouteau, Franck; Champion, Nicolas; Bigot, Antony. COA of Formula: C20H20BrPThis research focused ontomaymycin oxo total synthesis chemoselective reduction cyclization. The article conveys some information:

(+)-Oxo-tomaymycin (I), a naturally occurring substance of the pyrrolo-1,4-benzodiazepine family, was synthesized using a short and efficient route. The key construction of the seven-membered ring by amide bond formation was realized via a chemoselective Aryl-NO2 reduction using TiCl3 under acidic conditions, followed by a spontaneous cyclization. This synthesis was easily scaled up to 80 g, and it should be amenable to the production of larger quantities.Ethyltriphenylphosphonium bromide(cas: 1530-32-1COA of Formula: C20H20BrP) was used in this study.

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. CatOnium ETPB is also used as catalysts in the synthesis of certain organic compounds.COA of Formula: C20H20BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Palomino-Ruiz, Lucia; Rodriguez-Gonzalez, Sandra; Fallaque, Joel G.; Marquez, Irene R.; Agrait, Nicolas; Diaz, Cristina; Leary, Edmund; Cuerva, Juan M.; Campana, Araceli G.; Martin, Fernando; Millan, Alba; Gonzalez, M. Teresa published their research in Angewandte Chemie, International Edition in 2021. The article was titled 《Single-Molecule Conductance of 1,4-Azaborine Derivatives as Models of BN-doped PAHs》.Name: 9,10-Dibromoanthracene The article contains the following contents:

The single-mol. conductance of a series of BN-acene-like derivatives has been measured by using scanning tunneling break-junction techniques. A strategic design of the target mols. has allowed us to include azaborine units in positions that unambiguously ensure electron transport through both heteroatoms, which is relevant for the development of customized BN-doped nanographenes. We show that the conductance of the anthracene azaborine derivative is comparable to that of the pristine all-carbon anthracene compound Notably, this heteroatom substitution has also allowed us to perform similar measurements on the corresponding pentacene-like compound, which is found to have a similar conductance, thus evidencing that B-N doping could also be used to stabilize and characterize larger acenes for mol. electronics applications. Our conclusions are supported by state-of-the-art transport calculations In the part of experimental materials, we found many familiar compounds, such as 9,10-Dibromoanthracene(cas: 523-27-3Name: 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) can be sublimated and oxidized to generate anthraquinone. Soluble in hot benzene and hot toluene, slightly soluble in alcohol, ether and cold benzene, insoluble in water.Name: 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

COA of Formula: Br3InIn 2020 ,《A radical-mediated 1,3,4-trifunctionalization cascade of 1,3-enynes with sulfinates and tert-butyl nitrite: facile access to sulfonyl isoxazoles》 was published in Chemical Communications (Cambridge, United Kingdom). The article was written by Yue, Xin; Hu, Ming; He, Xingyi; Wu, Shuang; Li, Jin-Heng. The article contains the following contents:

An unprecedented indium-promoted three-component 1,3,4-trifunctionalization cascade of 1,3-enynes with sodium sulfinates and tert-Bu nitrite (TBN) to access 5-sulfonylisoxazoles I [R1 = Ph, 3-thienyl, CH2OCOPh, etc.; R2 = H, Me; R3 = Me, cyclopropyl, Ph, etc.] via [3+2] annulation was reported. By employing TBN as both the radical initiator and the N-O two atom unit, this method enabled the formation of three new carbon-heteroatom bonds, C-S, C-N and C-O bonds, in a single reaction through a sequence of sulfonylation, isomerization, nitration and annulation with a broad substrate scope, excellent selectivity and the potential of late-stage functionalization of natural products. The experimental process involved the reaction of Indium(III) bromide(cas: 13465-09-3COA of Formula: Br3In)

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.COA of Formula: Br3In

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Related Products of 1779-49-3In 2019 ,《Effect of the Substituent Position on the Anionic Copolymerization of Styrene Derivatives: Experimental Results and Density Functional Theory Calculations》 appeared in Macromolecules (Washington, DC, United States). The author of the article were Johann, Tobias; Leibig, Daniel; Grune, Eduard; Mueller, Axel H. E.; Frey, Holger. The article conveys some information:

In a combined synthetic, kinetic and theor. study, the living anionic copolymerization of styrene and its ring-methylated derivatives ortho-, meta-, and para-methylstyrene (MS) was examined by real-time 1H NMR spectroscopy in the nonpolar solvents toluene-d8 and cyclohexane-d12 as well as by d. functional theory calculations Based on the NMR kinetics data, reactivity ratios for each comonomer pair were determined by the Kelen-Tudos method and numerical integration of the copolymerization equation (Contour software). The reaction pathway was modeled and followed by d. functional theory (DFT) calculations to validate and predict the exptl. derived reactivity ratios. Unexpectedly, two of the three styrene derivatives showed completely different reactivities in copolymerization, governed by the position of the Me group. While para-MS is considerably less reactive than styrene, resulting in gradient copolymers (rS = 2.62; rpMS = 0.37), ortho-MS showed the opposite behavior and is more reactive than styrene (rS = 0.44; roMS = 2.47), leading to a reversal of the copolymers’ gradient. The substitution in the meta-position had nearly no influence on monomer reactivity, and copolymers with close to random comonomer distribution were formed (rS = 0.81; rmMS = 1.21). In all cases, the theor. calculations showed good to excellent agreement with the exptl. data. Monomer reactivities correlate with the chem. shifts of the β-carbon signals in 13C NMR spectra that are predictive for the gradient structure. The results demonstrate the possibility of tailoring and validating the polymer structures of functional polystyrene copolymers by the choice of the substitution pattern of styrene derivatives, using both exptl. and theor. approaches. In the part of experimental materials, we found many familiar compounds, such as Methyltriphenylphosphonium bromide(cas: 1779-49-3Related Products of 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Related Products of 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Santra, Somtirtha; Maharana, Debasis; Kotecha, Prakash; Banerjee, Tamal published an article in Industrial & Engineering Chemistry Research. The title of the article was 《Process Simulation and Multiobjective Optimization for High-Purity Hexane Recovery Using Deep Eutectic Solvent》.Name: Methyltriphenylphosphonium bromide The author mentioned the following in the article:

Deep eutectic solvents (DESs) are an exptl. proven and attractive solvent in the field of green chem. for aromatic extraction from a mixture of aliphatic-aromatic mixtures The current work reports a multiscale strategy using quantum chem. calculations, thermodn. models, process simulation, and multiobjective optimization for the simultaneous production of high-purity hexane and aromatic removal using the DES Me tri-Ph phosphonium bromide/ethylene glycol (1:4). Initially the phase equilibrium data have been benchmarked through the continuum solvation-based COSMO-SAC model, which has a root-mean-square deviation of 5.81%. Thereafter, a conceptual multiloop extraction and solvent recovery process has been developed and simulated that incorporates sensitivity anal. to analyze the impact of different process parameters on the system. These parameters, namely, annualized capital cost, benzene content in the hexane product stream, and hexane recovery, have been further formulated as three sep. objective functions to be optimized using a nondominated sorting genetic algorithm. After optimization, a series of solutions have been obtained from the Pareto front. The results provide 92% hexane recovery with a benzene concentration of less than 50 ppm. This shall enable the industrial production of high-purity hexane using efficient and sustainable green solvents. The experimental process involved the reaction of Methyltriphenylphosphonium bromide(cas: 1779-49-3Name: Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Name: Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary