Tag: 300-400

Wu, Xiang; Ding, Du; Zhang, Ying; Jiang, Hua-Jie; Wang, Tao; Zhao, Li-Ping published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Enantioselective synthesis of 1-aminoindene derivatives via asymmetric Bronsted acid catalysis》.Computed Properties of C20H20BrP The article contains the following contents:

A catalytic asym. iminium ion cyclization reaction of simple 2-alkenylbenzaldimines using a BINOL-derived chiral N-triflyl phosphoramide was described. The corresponding 1-aminoindenes I [R1 = H, Ph, Bn, etc.; R2 = H, Me, Ph, etc.; R3 = H, 5-F, 5-Me, etc.] and tetracyclic 1-aminoindanes II [R4 = H, Me, Et, etc.] were formed in good yields and high enantioselectivities. Further, the chem. utility of the obtained enantiopure 1-aminoindene was demonstrated for the asym. synthesis of (S)-rasagiline. The experimental process involved the reaction of Ethyltriphenylphosphonium bromide(cas: 1530-32-1Computed Properties of C20H20BrP)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.Computed Properties of C20H20BrP

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Journal of the American Chemical Society included an article by Daub, Mary Elisabeth; Jung, Hoimin; Lee, Byung Joo; Won, Joonghee; Baik, Mu-Hyun; Yoon, Tehshik P.. Safety of Methyltriphenylphosphonium bromide. The article was titled 《Enantioselective [2+2] Cycloadditions of Cinnamate Esters: Generalizing Lewis Acid Catalysis of Triplet Energy Transfer》. The information in the text is summarized as follows:

We report the enantioselective [2+2] cycloaddition of simple cinnamate esters, the products of which are useful synthons for the controlled assembly of cyclobutane natural products. This method utilizes a cocatalytic system in which a chiral Lewis acid accelerates the transfer of triplet energy from an excited-state Ir(III) photocatalyst to the cinnamate ester. Computational evidence indicates that the principal role of the Lewis acid cocatalyst is to lower the absolute energies of the substrate frontier MOs, leading to greater electronic coupling between the sensitizer and substrate and increasing the rate of the energy transfer event. These results suggest Lewis acids can have multiple beneficial effects on triplet sensitization reactions, impacting both the thermodn. driving force and kinetics of Dexter energy transfer. In the part of experimental materials, we found many familiar compounds, such as Methyltriphenylphosphonium bromide(cas: 1779-49-3Safety of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Safety of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Synthetic Route of Br3InIn 2022 ,《Introducing the Catalytic Amination of Silanes via Nitrene Insertion》 was published in Journal of the American Chemical Society. The article was written by Rodriguez, Anabel M.; Perez-Ruiz, Jorge; Molina, Francisco; Poveda, Ana; Perez-Soto, Raul; Maseras, Feliu; Diaz-Requejo, M. Mar; Perez, Pedro J.. The article contains the following contents:

The direct functionalization of Si-H bonds by the nitrene insertion methodol. is described. A Cu(I) complex bearing a trispyrazolylborate ligand catalyzes the transfer of a nitrene group from PhI:NTs to the Si-H bond of silanes, disilanes, and siloxanes, leading to the exclusive formation of Si-NH moieties in the 1st example of this transformation. The process tolerates other functionalities in the substrate such as several C-H bonds and alkyne and alkene moieties directly bonded to the Si center. D. functional theory (DFT) calculations provide a mechanistic interpretation consisting of a Si-H homolytic cleavage and subsequent rebound to the Si-centered radical. In the experiment, the researchers used Indium(III) bromide(cas: 13465-09-3Synthetic Route of Br3In)

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Synthetic Route of Br3In

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Application of 1779-49-3In 2019 ,《Rhodium(III) vs. cobalt(III): a mechanistically distinct three-component C-H bond addition cascade using a Cp*RhIII catalyst》 appeared in Chemical Communications (Cambridge, United Kingdom). The author of the article were Li, Ruirui; Ju, Cheng-Wei; Zhao, Dongbing. The article conveys some information:

Three-component C-H bond additions across two different coupling partners remain underdeveloped. Herein, we report the first three-component RhIII-catalyzed C-H bond additions to a wide range of dienes and aldehydes. Our method constitutes a complementary access with Ellman’s CoIII-catalytic system to homoallylic alcs. The results came from multiple reactions, including the reaction of Methyltriphenylphosphonium bromide(cas: 1779-49-3Application of 1779-49-3)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is a lipophilic molecule with a cation allowing for it to be used to deliver molecules to specific cell components. Also considered an antineoplastic agent.Application of 1779-49-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Photo-regulated supramolecular star with a pillar[6]arene-coated metal-organic polyhedron (MOP) core》 was written by Hao, Xiang; Leng, Zejian; Sun, Dan; Peng, Feng; Yasin, Akram. SDS of cas: 6825-20-3 And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

Authors herein report a 12-armed photo-responsive supramol. star centered by a pillar[6]arene-coated M6L12 metal-organic polyhedron (MOP) via a core-first approach. In the experiment, the researchers used many compounds, for example, 3,6-Dibromo-9H-carbazole(cas: 6825-20-3SDS of cas: 6825-20-3)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.SDS of cas: 6825-20-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Bi(OAc)3/chiral phosphoric acid catalyzed enantioselective allylation of isatins》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Wang, Jie; Zhang, Qingxia; Li, Yao; Liu, Xiangshuai; Li, Xin; Cheng, Jin-Pei. COA of Formula: Br3In The article mentions the following:

An efficient protocol for construction of chiral 3-allyl-3-hydroxyoxindoles I (R = 4-Cl, 5-Br, 6-F, etc.; R1 = Me, Ph, naphthalen-1-ylmethyl, etc.) via the enantioselective allylation reaction of isatins II and allylboronates CH2=CH(R2)C(R3)(R4)B(-OC(CH3)2C(CH3)2O-) (R2 = R3 = R4 = H, Me) catalyzed by a simple binary acid Bi(OAc)3/chiral phosphoric acid system under mild conditions was disclosed. The synthetic utility of this strategy has been demonstrated through the formal synthesis of ent-CPC-1. In the experiment, the researchers used many compounds, for example, Indium(III) bromide(cas: 13465-09-3COA of Formula: Br3In)

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.COA of Formula: Br3In

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Journal of the American Chemical Society included an article by Whidbey, Christopher; Sadler, Natalie C.; Nair, Reji N.; Volk, Regan F.; DeLeon, Adrian J.; Bramer, Lisa M.; Fansler, Sarah J.; Hansen, Joshua R.; Shukla, Anil K.; Jansson, Janet K.; Thrall, Brian D.; Wright, Aaron T.. Application In Synthesis of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate. The article was titled 《A Probe-Enabled Approach for the Selective Isolation and Characterization of Functionally Active Subpopulations in the Gut Microbiome》. The information in the text is summarized as follows:

Commensal microorganisms in the mammalian gut play important roles in host health and physiol., but a central challenge remains in achieving a detailed mechanistic understanding of specific microbial contributions to host biochem. New function-based approaches are needed that analyze gut microbial function at the mol. level by coupling detection and measurements of in situ biochem. activity with identification of the responsible microbes and enzymes. The authors developed a platform employing β-glucuronidase selective activity-based probes to detect, isolate, and identify microbial subpopulations in the gut responsible for this xenobiotic metabolism Metabolic activity of gut microbiota can be plastic and between individuals and during perturbation, phylogenetically disparate populations can provide β-glucuronidase activity. The authors’ work links biochem. activity with mol.-scale resolution without relying on genomic inference. In the experimental materials used by the author, we found (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3Application In Synthesis of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate)

(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.Application In Synthesis of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Leaping across the visible range: near-infrared-to-violet photon upconversion employing a silyl-substituted anthracene》 was written by Haruki, Rena; Sasaki, Yoichi; Masutani, Kouta; Yanai, Nobuhiro; Kimizuka, Nobuo. Application In Synthesis of 9,10-Dibromoanthracene And the article was included in Chemical Communications (Cambridge, United Kingdom) in 2020. The article conveys some information:

Upconverting near-IR (NIR) light (λ > 700 nm) to violet light (λ < 450 nm) based on triplet-triplet annihilation (TTA) is achieved for the first time by developing a silyl-substituted anthracene violet emitter and its sensitization by an osmium complex showing a singlet-to-triplet (S-T) absorption in the NIR range. In the experimental materials used by the author, we found 9,10-Dibromoanthracene(cas: 523-27-3Application In Synthesis of 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) is synthesized by the bromination of anthracene. The bromination reaction is carried out at room temperature using carbon tetrachloride as a solvent. Using 80-85% anthracene as raw material, adding bromine to react for half an hour, the yield is 83-88%.Application In Synthesis of 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Density Functional Study of Methane Activation by Frustrated Lewis Pairs with Group 13 Trihalides and Group 15 Pentahalides and a Machine Learning Analysis of Their Barrier Heights》 was written by Migliaro, Ignacio; Cundari, Thomas R.. Application In Synthesis of Indium(III) bromide And the article was included in Journal of Chemical Information and Modeling in 2020. The article conveys some information:

Frustrated Lewis pairs (FLP) are an important advancement in metal-free catalysis. FLPs activate a variety of small mols., notably dihydrogen. Methane activation, however, has not been reported despite it being an abundant chem. feedstock. D. functional theory calculations were utilized to elucidate the reaction mechanism of methane activation by triel trihalide and pnictogen pentahalide-ammonia Lewis pairs. Two reaction mechanisms were modeled for methane activation: proton abstraction and hydride abstraction. In all cases, deprotonation was thermodynamically and kinetically favored vs. hydride abstraction. The use of heavier pnictogens and bigger triels were calculated to be more favorable for the activation of methane. To discern factors affecting the activation energies, different descriptors were correlated-ground state thermodn., orbital energies, transition state strain energies, etc.-but no consistent patterns were identified. Thus, machine learning methods were used to correlate ground state parameters to barrier heights. A neural network was used to correlate ground state descriptors (global electrophilicity index, bond dissociation energies, reaction energies) to activation free energies (R2 = 0.90). The experimental process involved the reaction of Indium(III) bromide(cas: 13465-09-3Application In Synthesis of Indium(III) bromide)

Indium(III) bromide(cas: 13465-09-3) is used in organic synthesis as a water tolerant Lewis acid. It efficiently catalyzes the three-component coupling of β-keto esters, aldehydes and urea (or thiourea) to afford the corresponding dihydropyrimidinones.Application In Synthesis of Indium(III) bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Piezoelectric Energy Harvesting from a Ferroelectric Hybrid Salt [Ph3MeP]4[Ni(NCS)6] Embedded in a Polymer Matrix》 was written by Vijayakanth, Thangavel; Ram, Farsa; Praveenkumar, Balu; Shanmuganathan, Kadhiravan; Boomishankar, Ramamoorthy. Quality Control of Methyltriphenylphosphonium bromide And the article was included in Angewandte Chemie, International Edition in 2020. The article conveys some information:

Organic-inorganic hybrid ferroelecs. are an exciting class of mol. materials with promising applications in the area of energy and electronics. The synthesis, ferroelec. and piezoelec. energy harvesting behavior of a 3d metal ion-containing A4BX6 type organic-inorganic hybrid salt [Ph3MeP]4[Ni(NCS)6] (1) is now presented. P-E hysteresis loop studies on 1 show a remnant ferroelec. polarization value of 18.71 μC cm-2, at room temperature Composite thermoplastic polyurethane (TPU) devices with 5, 10, 15 and 20 wt % compositions of 1 were prepared and employed for piezoelec. energy harvesting studies. A maximum output voltage of 19.29 V and a calculated power d. value of 2.51 mW cm-3 were observed for the 15 wt % 1-TPU device. The capacitor charging experiments on the 15 wt % 1-TPU composite device shows an excellent energy storage performance with the highest stored energies and measured charges of 198.8 μJ and 600 μC, resp. After reading the article, we found that the author used Methyltriphenylphosphonium bromide(cas: 1779-49-3Quality Control of Methyltriphenylphosphonium bromide)

Methyltriphenylphosphonium bromide(cas: 1779-49-3) is an organophosphorus compound, with potential use as a precursor and a solvent in organic synthesis. And it is used widely for methylenation via the Wittig reaction.Quality Control of Methyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary