Tag: 300-400

《Cooperativity within the catalyst: alkoxyamide as a catalyst for bromocyclization and bromination of (hetero)aromatics》 was published in Chemical Communications (Cambridge, United Kingdom) in 2020. These research results belong to Mondal, Haripriyo; Sk, Raja Md; Maji, Modhu Sudan. Computed Properties of C14H8Br2 The article mentions the following:

N-Methoxy-1-butanesulfonamide was a recyclable catalyst for the activation of N-bromosuccinimide to perform bromocyclization and bromination reactions of unsaturated carboxylic acids, alkenes and indoles with pendant nucleophiles, and arenes in heptane, where adequate suppression of the background reactions was observed, to yield bromolactones, bromomethyl-substituted heterocycles, fused indolines such as pyrroloindolines, and aryl bromides. The key feature of the active site is the alkoxy group attached to the sulfonamide moiety, which facilitates the acceptance as well as the delivery of bromonium species from the bromine source to the substrates. In the experiment, the researchers used 9,10-Dibromoanthracene(cas: 523-27-3Computed Properties of C14H8Br2)

9,10-Dibromoanthracene(cas: 523-27-3) can be sublimated and oxidized to generate anthraquinone. Soluble in hot benzene and hot toluene, slightly soluble in alcohol, ether and cold benzene, insoluble in water.Computed Properties of C14H8Br2

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Henriques, Dina Schwarz G.; Rojo-Wiechel, Elena; Klare, Sven; Mika, Regine; Hothker, Sebastian; Schacht, Jonathan H.; Schmickler, Niklas; Gansauer, Andreas published an article in Angewandte Chemie, International Edition. The title of the article was 《Titanocene(III)-Catalyzed Precision Deuteration of Epoxides》.Application In Synthesis of Ethyltriphenylphosphonium bromide The author mentioned the following in the article:

Authors describe a titanocene(III)-catalyzed deuterosilylation of epoxides that provides β-deuterated anti-Markovnikov alcs. with excellent D-incorporation, in high yield, and often excellent diastereoselectivity after desilylation. The key to the success of the reaction is a novel activation method of Cp2TiCl2 and (tBuC5H4)2TiCl2 with BnMgBr and PhSiD3 to provide [(RC5H4)2Ti(III)D] without isotope scrambling. It was developed after discovering an off-cycle scrambling with the previously described method. Precision deuteration can be applied to the synthesis of drug precursors and highlights the power of combining radical chem. with organometallic catalysis. In the experiment, the researchers used many compounds, for example, Ethyltriphenylphosphonium bromide(cas: 1530-32-1Application In Synthesis of Ethyltriphenylphosphonium bromide)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.Application In Synthesis of Ethyltriphenylphosphonium bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Murai, Masahito; Nishimura, Kengo; Takai, Kazuhiko. HPLC of Formula: 1530-32-1. The article was titled 《Palladium-catalyzed double-bond migration of unsaturated hydrocarbons accelerated by tantalum chloride》. The information in the text is summarized as follows:

The operationally simple palladium-catalyzed double-bond migration without heteroatom-containing coordinating functional groups was described. Addition of TaCl5 as a second catalyst greatly enhanced the migration efficiency to provided β-alkylstyrenes through migration of up to a five-carbon chain. Both catalysts were com. available and the reaction occurred without external ligands under neutral conditions. The reaction proceeded via generation of π-allyl palladium species, which enabled the chemoselective double-bond migration of hydrocarbons in the presence of allyl ethers. Remote functionalization through double-bond migration was also demonstrated using FeCl3 as a second catalyst. In the experiment, the researchers used Ethyltriphenylphosphonium bromide(cas: 1530-32-1HPLC of Formula: 1530-32-1)

Ethyltriphenylphosphonium bromide(cas: 1530-32-1) is a phase transfer catalyst, used to accelerate the cure of phenolic-based epoxy resins, certain fluoroelastomer resins and thermosetting powder coatings. It is also used as catalysts in the synthesis of certain organic compounds and as a pharmaceutical intermediate.HPLC of Formula: 1530-32-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Schmidt, Maximilian; Wassy, Daniel; Hermann, Mathias; Gonzalez, M. Teresa; Agraeit, Nicolas; Zotti, Linda A.; Esser, Birgit; Leary, Edmund published their research in Chemical Communications (Cambridge, United Kingdom) in 2021. The article was titled 《Single-molecule conductance of dibenzopentalenes: antiaromaticity and quantum interference》.HPLC of Formula: 523-27-3 The article contains the following contents:

The effects of antiaromaticity and destructive quantum interference (DQI) are investigated on the charge transport through dibenzo-[a,e]pentalene (DBP). 5,10-Connectivity gives high single-mol. conductance whereas 2,7 gives low conductance due to DQI. Comparison of the 5,10-DBP with Ph and anthracene analogs yields the trend GDBP ≈ GAnth > GPh, despite the aromatic anthracene having a larger HOMO-LUMO gap than 5,10-DBP. This is explained by unfavorable level alignment for 5,10-DBP. After reading the article, we found that the author used 9,10-Dibromoanthracene(cas: 523-27-3HPLC of Formula: 523-27-3)

9,10-Dibromoanthracene(cas: 523-27-3) is synthesized by the bromination of anthracene. The bromination reaction is carried out at room temperature using carbon tetrachloride as a solvent. Using 80-85% anthracene as raw material, adding bromine to react for half an hour, the yield is 83-88%.HPLC of Formula: 523-27-3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Glucuronidation of Methylated Quercetin Derivatives: Chemical and Biochemical Approaches》 was written by Docampo-Palacios, Maite L.; Alvarez-Hernandez, Anislay; Adiji, Olubu; Gamiotea-Turro, Daylin; Valerino-Diaz, Alexander B.; Viegas, Luis P.; Ndukwe, Ikenna E.; de Fatima, Angelo; Heiss, Christian; Azadi, Parastoo; Pasinetti, Giulio M.; Dixon, Richard A.. Category: bromides-buliding-blocks And the article was included in Journal of Agricultural and Food Chemistry in 2020. The article conveys some information:

Botanical supplements derived from grapes are functional in animal model systems for the amelioration of neurol. conditions, including cognitive impairment. Rats fed with grape extracts accumulate 3′-O-methyl-quercetin-3-O-β-D-glucuronide in their brains, as a potential therapeutic agent. To develop methods for the synthesis of 3′-O-methyl-quercetin-3-O-β-D-glucuronide and the related 4′-O-methyl-quercetin-7-O-β-D-glucuronide, 3-O-methyl-quercetin-3′-O-β-D-glucuronide, and 4′-O-methyl-quercetin-3′-O-β-D-glucuronide, which are not found in the brain, we have evaluated both enzymic semi-synthesis and full chem. synthetic approaches. Biocatalysis by mammalian UDP-glucuronosyltransferases generated multiple glucuronidated products from 4′-O-methylquercetin, and is not cost-effective. Chem. synthetic methods, on the other hand, provided good results; methyl-quercetin-3-O-β-D-glucuronides were obtained in six steps at 12-30% overall yield, resp., while 4 was synthesized in five steps at 34% overall yield. A mechanistic study on the unexpected regioselectivity observed in the quercetin glucuronide synthetic steps is also presented. The results came from multiple reactions, including the reaction of (2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3Category: bromides-buliding-blocks)

(2R,3R,4S,5S,6S)-2-Bromo-6-(methoxycarbonyl)tetrahydro-2H-pyran-3,4,5-triyl triacetate(cas: 21085-72-3) may be used for the synthesis of HMR1098-S-Glucuronide Methyl Ester, a new K-ATP-blocking agent being developed as a drug for prevention of sudden cardiac death.Category: bromides-buliding-blocks

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《One-pot synthesis of a white-light emissive bichromophore operated by aggregation-induced dual emission (AIDE) and partial energy transfer》 was written by Denissen, Melanie; Hannen, Ricarda; Itskalov, Dana; Biesen, Lukas; Nirmalananthan-Budau, Nithiya; Hoffmann, Katrin; Reiss, Guido J.; Resch-Genger, Ute; Mueller, Thomas J. J.. Synthetic Route of C12H7Br2NThis research focused onwhite light fluorescence bichromophore aggregation induced emission energy transfer. The article conveys some information:

Merocyanine-triarylamine bichromophores are readily synthesized by sequentially Pd-catalyzed insertion-alkynylation-Michael-Suzuki four-component reactions. White-light emissive systems form upon aggregation in 1 : 99 and 0.1 : 99.9 vol% CH2Cl2-cyclohexane mixtures, ascribed to aggregation-induced dual emission (AIDE) in combination with partial energy transfer between both chromophore units as supported by spectroscopic studies. The experimental part of the paper was very detailed, including the reaction process of 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Synthetic Route of C12H7Br2N)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Synthetic Route of C12H7Br2N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Recommanded Product: 3,6-Dibromo-9H-carbazoleIn 2022 ,《Carbazole-siloxane based polymers for the selective detection of 4-nitrophenol and Fe3+》 was published in Journal of Photochemistry and Photobiology, A: Chemistry. The article was written by Wang, Aijing; Tian, Minggang; Zuo, Yujing; Gou, Zhiming. The article contains the following contents:

Silicone-containing polymers have broad application prospects in the detection of many analytes due to their unique fluorescence properties. Environmental pollutants are very complex, which have prompted researchers to explore different detection methods. In this report, two kinds of polymers were synthesized via Heck-reaction between tetramethyltetravinylcyclotetrasiloxane (Dvi4) and carbazole derivatives The polymers showed excellent fluorescent properties and exhibited high sensitivity to 4-nitrophenol (4-NP) and Fe3+ in solution Furthermore, the polymers still showed high sensitivity for Fe3+ in living cells. We estimate that the cyclic structure of Dvi4 and carbazole structure will serve as responsive sites for Fe3+ and 4-NP, resp. The frontier MOs of polymers were calculated by Materials Studio and the effect of the cyclic structure of Dvi4 on their responsiveness had been discussed. The design idea of the polymer sensors can provide a new direction for the synthesis of multi-response polymer fluorescent probes. In the experiment, the researchers used 3,6-Dibromo-9H-carbazole(cas: 6825-20-3Recommanded Product: 3,6-Dibromo-9H-carbazole)

3,6-Dibromo-9H-carbazole(cas: 6825-20-3) is used as a pharmaceutical intermediate, and also an important intermediate of synthesizing optoelectronic materials. It has been used in the preparation of N-(2-hydroxyethyl)-3,6-dibromocarbazole.Recommanded Product: 3,6-Dibromo-9H-carbazole

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2019,Chemical Communications (Cambridge, United Kingdom) included an article by Mondal, Mukulesh; Panda, Manashi; Davis, Nicholas W.; McKee, Vickie; Kerrigan, Nessan J.. Application In Synthesis of Indium(III) bromide. The article was titled 《Asymmetric synthesis of cyclopentanones through dual Lewis acid-catalysed [3+2]-cycloaddition of donor-acceptor cyclopropanes with ketenes》. The information in the text is summarized as follows:

When InBr3-EtAlCl2 (15-30 mol%) was used as a dual Lewis acid system to promote the formal [3+2]-cycloaddition of enantioenriched donor-acceptor cyclopropanes I (R1 = C2H3, Ph, C2H2C6H4; R2 = 2-methoxy-2-oxoethyl, 2-ethoxy-2-oxoethyl, 2-(benzyloxy)-2-oxoethyl) with ketenes (O)CC(R3)(R4) (R3 = 4-methylphenyl, 4-(trifluoromethyl)phenyl, cyclohexyl, etc.; R4 = Et, Ph, Me, n-butyl), cyclopentanones II were formed in good to excellent yields (84-99%, 18 examples), and with excellent transfer of chirality (15 examples, 90% ee to >99% ee). In addition to this study using Indium(III) bromide, there are many other studies that have used Indium(III) bromide(cas: 13465-09-3Application In Synthesis of Indium(III) bromide) was used in this study.

Indium(III) bromide(cas: 13465-09-3) is used as a catalyst to produce dithioacetals when unactivated alkynes react with thiols and fields such as optics and microelectronics that utilize semiconductor technology have wide uses for indium in high-performing solar cells.Application In Synthesis of Indium(III) bromide

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

In 2022,Asfandiarov, N. L.; Muftakhov, M. V.; Rakhmeev, R. G.; Safronov, A. M.; Markova, A. V.; Pshenichnyuk, S. A. published an article in Journal of Electron Spectroscopy and Related Phenomena. The title of the article was 《Non covalent bonds in some bromo-substituted aromatic anions》.Name: 9,10-Dibromoanthracene The author mentioned the following in the article:

Four bromo-substituted derivatives of naphthalene and anthracene were studied by means of Dissociative Electron Attachment Spectroscopy. Long-lived mol. anions with lifetimes ranging from 25 to 144μs were observed in all mols. under investigation. In all cases mol. anion fragmentation is poor: only the Br- , [M-Br]- and (with very small intensity) [M-H]- species were observed, except for the case of 9,10-Br2-anthracene. It was shown that the presence of long-lived mol. anions in 1-Br- and 2-Br-naphthalene (τa = 26μs and τa = 25μs, resp.) does not contradict the fact that their dissociation rates measured by the pulse radiolysis method are fairly large (1.0 x1010 s-1 and 1.8 x1010 s-1, resp.). Scanning the potential energy surface of anions in the process of positioning a bromine anion around a polarized aromatic radical revealed the presence of a series of local min. separated by potential barriers. It is inferred that the most energetically favorable structures of the 1-Br- and 2-Br-naphthalene anions should be interpreted as complexes of the bromide anion bound to the polarized aromatic radical by non-covalent Br-H bonds. Similar local min. were found in the 9-Br- and 9,10-Br2-anthracene anions, but the energies of these structures are significantly higher than those of the “”standard”” anionic structures with a C-Br bond length of ∼1.93 Å. The EAas obtained with DFT CAM-B3LYP/6-311 +G(d,p) calculations are in acceptable agreement with the estimates made within the framework of the simple Arrhenius model from the lifetimes of mol. anions. In the experiment, the researchers used many compounds, for example, 9,10-Dibromoanthracene(cas: 523-27-3Name: 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) can be sublimated and oxidized to generate anthraquinone. Soluble in hot benzene and hot toluene, slightly soluble in alcohol, ether and cold benzene, insoluble in water.Name: 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Bimetallic ethynylanthracenyl functionalised carbynes》 was written by Frogley, Benjamin J.; Hill, Anthony F.; Welsh, Steven S.. Name: 9,10-DibromoanthraceneThis research focused ontungsten carbyne pyrazolylborate complex anthracenyl preparation alkynylation metalation coupling; crystal mol structure tungsten carbyne pyrazolylborate anthracenyl alkyne complex. The article conveys some information:

Mono- and bimetallic anthracenes functionalized by alkynyl and alkylidynyl substituents are obtained via sequential cross-coupling reactions of the 9-bromoanthracenyl carbyne [W{CC(C6H4)2CBr}(CO)2(Tp*)] (1). The compound 1 undergoes ethynylation, auration, oxidative coupling and Sonogashira coupling reactions giving a number of tungsten carbyne complexes functionalized with alkynyl and arylalkynyl substituents. The experimental part of the paper was very detailed, including the reaction process of 9,10-Dibromoanthracene(cas: 523-27-3Name: 9,10-Dibromoanthracene)

9,10-Dibromoanthracene(cas: 523-27-3) is a dibrominated polycyclic aromatic hydrocarbon (PAH). 9,10-Dibromoanthracene is often used as an energy acceptor and activator in reactions that produce chemiluminescence.Name: 9,10-Dibromoanthracene

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary