Tag: 400-500

《Crystal structure of tris[4-(naphthalen-1-yl)phenyl]amine》 was written by Yano, Masafumi; Kashiwagi, Yukiyasu; Inada, Yoshinori; Hayashi, Yuki; Mitsudo, Koichi; Kubono, Koji. Synthetic Route of C18H12Br3NThis research focused ontris naphthalen phenyl amine dimer crystal structure hydrogen bond; crystal structure; electroluminescence; hole transporter; organic electronics; tri­aryl­amine. The article conveys some information:

In the title mol., C48H33N, the central N atom shows no pyramidalization, so that the N atom and the three C atoms bound to the N atom lie almost in the same plane. The three para-phenylene rings bonded to the N atom are in a propeller form. All of the naphthalene ring systems are slightly bent. In the crystal, mols. form an inversion dimer, through two pairs of C-H···π interactions, which further interacts with the adjacent dimer via another two pairs of C-H···π interactions, forming a column structure along the a axis. There are no significant interactions between these column structures. The experimental process involved the reaction of Tris(4-bromophenyl)amine(cas: 4316-58-9Synthetic Route of C18H12Br3N)

In general, Tris(4-bromophenyl)amine(cas: 4316-58-9) is often used in the synthesis of porous luminescent covalent–organic polymers (COPs)Synthetic Route of C18H12Br3N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Ferrocene-based hyperbranched polymers: a synthetic strategy for shape control and applications as electroactive materials and precursor-derived magnetic ceramics》 was written by Wei, Zhuoxun; Wang, Dong; Liu, Yurong; Guo, Xuyun; Zhu, Ye; Meng, Zhengong; Yu, Zhen-Qiang; Wong, Wai-Yeung. Reference of Tris(4-bromophenyl)amine And the article was included in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices in 2020. The article conveys some information:

The stable sandwich structure and the excellent redox activity of ferrocene make it a ubiquitous component in organometallic systems. The introduction of a ferrocenyl unit into a polymer skeleton provides a good avenue towards novel materials for various applications in redox batteries, enantioselective catalysis, optical and magnetic switches, etc. Herein, we report a strategic design and synthesis of new ferrocene-based hyperbranched polymers, and demonstrate promising methods for their morphol. control as spheres by direct coupling reactions and hollow polyhedra by a templating approach. Furthermore, task-specific applications targeted for their resp. architectures are investigated in lithium ion batteries (LIBs) and water treatment, resp. The spherical polymer used as an electroactive anode in LIBs has a high capacity of 755.2 mA h g-1, stable chargeable performance of over 200 cycles and superior rate capability. For comparison, the hollow counterpart shows a sharp increase of the sp. surface area in the precursor-derived magnetic ceramics from 417 to 1195 m2 g-1, and the as-made material exhibits great potential for the rapid removal of trace amounts of pollutants in water with magnetic reusability. In the part of experimental materials, we found many familiar compounds, such as Tris(4-bromophenyl)amine(cas: 4316-58-9Reference of Tris(4-bromophenyl)amine)

In other references, Tris(4-bromophenyl)amine(cas: 4316-58-9) is often used in the synthesis of porous luminescent covalent–organic polymers (COPs)Reference of Tris(4-bromophenyl)amine

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Organic light emitting devices based upon divalent osmium complexes: Part 1: design, synthesis, and characterization of osmium complexes》 was published in Proceedings of SPIE-The International Society for Optical Engineering in 2003. These research results belong to Carlson, Brenden; Phelan, Gregory D.; Jiang, Xuezhong; Kaminsky, Werner; Jen, Alex K. Y.; Dalton, Larry R.. Name: 4,7-Bis(4-bromophenyl)-1,10-phenanthroline The article mentions the following:

The authors present the synthesis and characterization of several novel osmium complexes [Os(N-N)2L-L]2+2X- designed for organic light emitting device (OLED) applications. In the complex notation N-N represents a derivative of 2,2′-bipyridine or 1,10-phenanthroline and L-L represents a strong π-acid arsine or phosphine ligand, 1,2-bis(diphenylarsino)ethane, 1,2-bis(diphenylarsino)ethene and 1,2-bis(diphenylphosphino)ethene. The complexes feature 3MLCT emission that ranges from 611-650 nm, which makes them suitable as an emission source for red OLEDs. Phosphorescent quantum yields ≤45% and emission lifetimes as short as 400 ns were reached. In the part of experimental materials, we found many familiar compounds, such as 4,7-Bis(4-bromophenyl)-1,10-phenanthroline(cas: 97802-08-9Name: 4,7-Bis(4-bromophenyl)-1,10-phenanthroline)

4,7-Bis(4-bromophenyl)-1,10-phenanthroline(cas: 97802-08-9) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Name: 4,7-Bis(4-bromophenyl)-1,10-phenanthroline Due to the reactivity of bromide, they are used as potential precursors or important intermediates in organic synthesis.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Reference of 4,7-Bis(4-bromophenyl)-1,10-phenanthrolineOn May 31, 1985, Alford, Peter C.; Cook, Michael J.; Lewis, Anthony P.; McAuliffe, Glenn S. G.; Skarda, Vladimir; Thomson, Andrew J.; Glasper, John L.; Robbins, David J. published an article in Journal of the Chemical Society, Perkin Transactions 2: Physical Organic Chemistry (1972-1999). The article was 《Luminescent metal complexes. Part 5. Luminescence properties of ring-substituted 1,10-phenanthroline tris-complexes of ruthenium(II)》. The article mentions the following:

The absorption characteristics, emission spectra, luminescent quantum yields, and lifetimes are reported for 24 Ru(II) tris-1,10-phenanthroline complexes in EtOH-MeOH solution Quantum yields were 0.019-0.403, the highest values being recorded for complexes substituted at the 4,7-sites with aryl groups. Incorporation of these derivatives into PVC film raised the quantum yields to 0.40-0.75. In the part of experimental materials, we found many familiar compounds, such as 4,7-Bis(4-bromophenyl)-1,10-phenanthroline(cas: 97802-08-9Reference of 4,7-Bis(4-bromophenyl)-1,10-phenanthroline)

4,7-Bis(4-bromophenyl)-1,10-phenanthroline(cas: 97802-08-9) belongs to organobromine compounds.Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Reference of 4,7-Bis(4-bromophenyl)-1,10-phenanthroline Alkyl bromides are mainly used as alkylating agents and also find application as a solvent to extract oil from seeds and wool.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Computed Properties of C18H12Br3NIn 2020 ,《Thiol-yne crosslinked triarylamine hole transport layers for solution-processable organic light-emitting diodes》 was published in Journal of Materials Chemistry C: Materials for Optical and Electronic Devices. The article was written by Kutonova, Ksenia; Ebenhoch, Bernd; Graf von Reventlow, Lorenz; Heissler, Stefan; Rothmann, Lukas; Braese, Stefan; Colsmann, Alexander. The article contains the following contents:

Triarylamine derivatives are widely used for hole transport in organic optoelectronic devices, but their excellent solubility in many common solvents limits their use for multi-layer device fabrication from solution In this work, a novel process to the formation of conjugated triarylamine polymer thin-film networks by crosslinking of thiol-substituted and alkyne-substituted triarylamines is investigated. After deposition of the monomer blend and crosslinking under UV exposure, an insoluble thiol-yne polymer network is formed. The applicability of the thiol-yne polymer network as hole-transport layers is exemplified on organic light-emitting diodes. Its implementation reduces the device degradation as compared to OLEDs comprising hole-transport layers from PEDOT:PSS. In addition to this study using Tris(4-bromophenyl)amine, there are many other studies that have used Tris(4-bromophenyl)amine(cas: 4316-58-9Computed Properties of C18H12Br3N) was used in this study.

In general, Tris(4-bromophenyl)amine(cas: 4316-58-9) is often used in the synthesis of porous luminescent covalent–organic polymers (COPs)Computed Properties of C18H12Br3N

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

《Solvent mediated thermodynamically favorable helical supramolecular self-assembly: recognition behavior towards achiral and chiral analytes》 was written by Kataria, Meenal; Kim, Youngseo; Chau, Hong Diem; Kwon, Na Yeon; Hong, Yongju; Kim, Taekyung; Ko, Jaewan; Son, Myung Kook; Bang, Joona; Park, Sungnam; Kim, Hugh I.; Lee, Kwangyeol; Choi, Dong Hoon. HPLC of Formula: 4316-58-9This research focused ontriphenylamine urea preparation mol recognition self assembly. The article conveys some information:

Herein, we successfully developed an entropically favored helical supramol. self-assembly from a triphenylamine-based derivative 4 in a green solvent in order to mimic the structural transformations that occur during the self-assembly of proteins/peptides which may cause various neurodegenerative diseases. Its structural transformation from helical supramol. self-assembly to a random coil and then achiral nanorods was studied by varying the concentration of achiral stimuli (i.e., Fe2+ ions). The driving force of this transformation is the strong binding affinity of chiral supramol. assemblies and Fe2+ ions. Furthermore, the “”metal-free”” helical supramol. self-assembly exhibited enantioselectivity for differentiating between L- and D-proline; this was achieved through a chiral stimuli-induced structural modulation methodol. Our evaluation of the effects of achiral/chiral stimuli is also novel. The results came from multiple reactions, including the reaction of Tris(4-bromophenyl)amine(cas: 4316-58-9HPLC of Formula: 4316-58-9)

In general, Tris(4-bromophenyl)amine(cas: 4316-58-9) is often used in the synthesis of porous luminescent covalent–organic polymers (COPs)HPLC of Formula: 4316-58-9

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Bucktowar, Kelvin published 《A review on bromhexine hydrochloride and the different analytical methods used for its determination》. The research results were published in《International Journal of Pharma and Bio Sciences》 in 2017.Reference of 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride The article conveys some information:

A review. Bromhexine hydrochloride is a mucolytic agent (expectorant) used in the treatment of respiratory disorders associated with viscid or excessive mucus. The active ingredient Bromhexine hydrochloride is an expectorant which works by loosening mucus in the chest, making it easier to cough up secretions. It is also used to treat productive, chesty coughs. It is chem. named 2-amino-3,5-dibromobenzyl (cyclohexyl) methylamine hydrochloride. According to IUPAC it is 2,4-dibromo-6-[[cyclohexyl (methyl) amino] methyl] aniline; hydrochloride. Bromhexine hydrochloride is a synthetic substance obtained as a synthetic analog of vasicine, a substance found in plants called Adhtoda vasica. The mechanism of action is based on phlegm degradation, thereby easing coughs. The different anal. methods used to quantify the drug as a single active pharmaceutical ingredient includes flow injection anal. with ion selective electrodes, inductively coupled plasma mass spectrometry, electrokinetic chromatog., electrochem. oxidation at the glassy carbon electrode, liquid chromatog., liquid gas chromatog., GC with mass detection, and Voltammetry. The drug has also been quantified in its combined formulations using HPLC, direct and derivative UV spectrophotometry. And 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride (cas: 611-75-6) was used in the research process.

2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) (BHH; 250μM; 24 hours) also significantly attenuates HGF-induced invasion of LNCaP and C4-2B cells that natively express TMPRSS2. No significant toxicity is observed over a 48-hour period exposing LNCaP, DU145, PC3, or HepG2 cells to Bromhexine hydrochloride concentrations ranging from 0μM to 250μM. Bromhexine hydrochloride exposure does not induce cell death or substantially suppress the growth of DU145 cells.Bromhexine hydrochloride (20 μM; 48 h) inhibits dendritic cells infection with HIV-1.Reference of 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Musdal, Yaman;Hegazy, Usama M.;Aksoy, Yasemin;Mannervik, Bengt published 《FDA-approved drugs and other compounds tested as inhibitors of human glutathione transferase P1-1》 in 2013. The article was appeared in 《Chemico-Biological Interactions》. They have made some progress in their research.Electric Literature of C14H21Br2ClN2 The article mentions the following:

Glutathione transferase P1-1 (GST P1-1) is often overexpressed in tumor cells and is regarded as a contributor to their drug resistance. Inhibitors of GST P1-1 are expected to counteract drug resistance and may therefore serve as adjuvants in the chemotherapy of cancer by increasing the efficacy of cytostatic drugs. Finding useful inhibitors among compounds used for other indications would be a shortcut to clin. applications and a search for GST P1-1 inhibitors among approved drugs and other compounds was therefore conducted. We tested 1040 FDA-approved compounds as inhibitors of the catalytic activity of purified human GST P1-1 in vitro. We identified chlorophyllide, merbromine, hexachlorophene, and ethacrynic acid as the most effective GST P1-1 inhibitors with IC₅₀ values in the low micromolar range. For comparison, these compounds were even more potent in the inhibition of human GST A3-3, an enzyme implicated in steroid hormone biosynthesis. In distinction from the other inhibitors, which showed conventional inhibition patterns, the competitive inhibitor ethacrynic acid elicited strong kinetic cooperativity in the glutathione saturation of GST P1-1. Apparently, ethacrynic acid serves as an allosteric inhibitor of the enzyme. In their own right, the compounds investigated are less potent than desired for adjuvants in cancer chemotherapy, but the structures of the most potent inhibitors could serve as leads for the synthesis of more efficient adjuvants. The experimental procedure involved many compounds, such as 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride (cas: 611-75-6) .

2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) is a mucolytic agent that exerts both a secretagogic action on submucosal glands and a mucolytic action toward acid glycoproteins inside cells. Bromhexine Hydrochloride is a medication prescribed for coughs which works by dissolving hard phlegm. OthersBromhexine is a mucolytic agent used in the treatment of respiratory disorders associated with viscid or excessive mucus. In addition, bromhexine has antioxidant properties. Electric Literature of C14H21Br2ClN2

Reference:
Bromide – Wikipedia,
bromide – Wiktionary

Yasui, Kosuke;Kamitani, Miharu;Fujimoto, Hayato;Tobisu, Mamoru published 《The Effect of the Leaving Group in N-Heterocyclic Carbene-Catalyzed Nucleophilic Aromatic Substitution Reactions》 in 2020. The article was appeared in 《Bulletin of the Chemical Society of Japan》. They have made some progress in their research.Recommanded Product: 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride The article mentions the following:

The reactivity order of the leaving group was F > Cl ≥ Br > I in N-heterocyclic carbene-catalyzed CS_NAr reactions of aryl halides bearing an α,β-unsaturated amide was discussed. Based on a qual. Marcus anal., the nature of the transition state in this catalytic CS_NAr was primarily determined by the potential energy of the Meisenheimer complex, even though it was not involved as a discrete intermediate in the reaction pathway.2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride (cas: 611-75-6) were involved in the experimental procedure.

2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride(cas: 611-75-6) is intended to support the body’s mechanisms for clearing mucus from the respiratory tract. Bromhexine is a synthetic derivative of the herbal active ingredient vasicine. It has been shown to increase the proportion of serous bronchial secretion, making it more easily expectorated. It is indicated as secretolytic therapy in bronchopulmonary diseases associated with abnormal mucus secretion and impaired mucus transport.Recommanded Product: 2,4-Dibromo-6-((cyclohexyl(methyl)amino)methyl)aniline hydrochloride

Reference:
Bromide – Wikipedia,
bromide – Wiktionary