Tag: M.W=150-200

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., SDS of cas: 70-23-5.

Erigur, Esra Caner;Altug, Cevher;Angeli, Andrea;Supuran, Claudiu T. research published 《 Design, synthesis and human carbonic anhydrase I, II, IX and XII inhibitory properties of 1,3-thiazole sulfonamides》, the research content is summarized as follows. A series of novel 1,3-thiazole sulfonamides I [R = i-Pr, n-Bu, HOCH₂CH₂, Ph(CH₂)₄, etc.] has been designed, synthesized and studied their carbonic anhydrase (CA) inhibitory properties. The inhibition property of four human CA isoforms was investigated: hCA I, II, IX, and XII using the standard drug acetazolamide (AAZ) for comparison. The compounds I showed a wide range of inhibition potency towards the cytosolic enzyme hCA I. Nevertheless, the compounds I (R = n-Pr, i-Pr, HOCH₂CHMe, HOCHMeCH₂, MeOCH₂CH₂) have shown higher inhibition potential as compared to acetazolamide (KI = 250 nM). The abundant human cytosolic isoform, hCA II, was strongly inhibited by the most compounds in low nanomolar range (KI < 12.1 nM). On the other hand, almost all novel synthesized compounds have shown weaker inhibition potential as compared to acetazolamide against the tumor membrane- associated isoform hCA IX. Finally, the second tumor membrane-associated isoform, hCA XII, showed a wide range of potency that spanned from 9.3 to 729.6 nM.

SDS of cas: 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. HPLC of Formula: 70-23-5.

Ertas, Merve;Biltekin, Sevde Nur;Berk, Barkin;Yurttas, Leyla;Demirayak, Seref research published 《 Synthesis of some 5,6-diaryl-1,2,4-triazine derivatives and investigation of their cyclooxygenase (COX) inhibitory activity》, the research content is summarized as follows. Within this study, [(diaryltriazinyl)thio]-N-(benzo/thiazolyl)acetamide derivatives (I [R = H,Me, Cl, etc.; R¹ = H, Me, COOEt; R² = H, Me; R¹R² = (CH₂)₃]) were synthesized and COX inhibitory activities of the compounds were investigated. Compounds I [R = MeO; R¹ = H, Me, COOEt;R² = H; R¹ = R² = Me; R¹R² = (CH₂)₄] , which have a 4-methoxyphenyl group within their structures, showed strong inhibitory activity on COX-2 enzyme, even compound I [R = MeO; R¹ = R² = H] namely 2-{[5,6-bis(4-methoxyphenyl)-1,2,4-triazin-3-yl]thio}-N-(thiazol-2-yl)acetamide exhibited higher selectivity on this enzyme (IC₅₀:3.06 μM). Mol. docking studies were performed for compound I [R = MeO; R¹ = R² = H] on COX-1 and COX-2 enzymes and the results were found to support the mol.′s COX-2 selectivity.

HPLC of Formula: 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Product Details of C5H7BrO3

Ezzatzadeh, Elham;Hargalani, Fariba Zamani;Shafaei, Faezeh research published 《 Bio-Fe₃O₄-MNPs Promoted Green Synthesis of Pyrido[2,1-a]isoquinolines and Pyrido[1,2-a]quinolines: Study of Antioxidant and Antimicrobial Activity》, the research content is summarized as follows. In this work, synthesis of pyrido[2,1-a]isoquinolines and pyrido[1,2-a]quinolines in excellent yield using multicomponent reaction of isoquinoline, Me malonyl chloride, alkyl bromides, and triphenylphosphine in the presence of catalytic amount of Fe₃O₄-MNPs in water at 80° were investigated. The reduction of ferric chloride solution with Clover Leaf water extract resulted in the synthesis of magnetic iron oxide nanoparticles (Fe₃O₄-NPs) as a green method. The antioxidant activity was studied for some newly synthesized compounds using the DPPH radical trapping and ferric ion reduction experiments and results were compared with synthetic antioxidants (TBHQ and BHT). These compounds showed trace DPPH radical trapping and excellent reducing strength of ferric ion. The antimicrobial activity of some synthesized compounds was studied employing the disk diffusion test on Gram-pos. bacteria and Gram-neg. bacteria. The results of disk diffusion test showed that these compounds prevented the bacterial growth.

70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., Product Details of C5H7BrO3

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

A variety of minor organobromine compounds are found in nature, but none are biosynthesized or required by mammals. 5445-17-0, formula is C4H7BrO2, Name is Methyl 2-bromopropanoate. Organobromine compounds have fallen under increased scrutiny for their environmental impact., Electric Literature of 5445-17-0.

Fan, Bo;Wan, Jing;McKay, Alasdair;Qu, Zhenyuan;Thang, San H. research published 《 Facile synthesis of well-controlled poly(1-vinyl imidazole) by the RAFT process》, the research content is summarized as follows. Poly(vinyl imidazole)s, which contain heterocyclic aromatic rings on the polymer side chains, are of increasing interest for a wide variety of applications ranging from catalysis, polymeric ionic liquids to membrane material. However, the controlled radical polymerization of vinyl imidazoles, including 1-vinyl imidazole (1VIM), 2-vinyl imidazole (2VIM) and 4-vinyl imidazole (4VIM), proved to be extremely challenging in the past decades. Here, we demonstrate, for the first time, that well-controlled and low dispersity (D as low as 1.05) poly(1VIM) could be synthesized via RAFT polymerization by using acetic acid as a special solvent. Acetic acid not only works as a solvent that allows homogeneous polymerization, it also protonates 1VIM, thereby, allowing the stabilization of propagating radicals during polymerization To verify the efficacy of the RAFT polymerization of 1VIM in acetic acid, various polymerization parameters including different RAFT agents, initiator and monomer concentrations, temperatures, etc. had been examined Moreover, detailed kinetic studies revealed a linear, pseudo-first-order polymerization behavior of 1VIM in acetic acid, and the apparent rate constants were calculated Furthermore, the living characteristic of this RAFT process was demonstrated by chain extension with Bu acrylate (nBA) and N,N-di-Me acrylamide (DMA) to form resp. block copolymers with low dispersities. Overall, the synthesis of well-controlled poly(1VIM) is expected to greatly expand the design and utility of vinyl imidazole-based materials and their applications in catalysis, membrane material, heavy metal removal, fuel cells and many other fields.

Electric Literature of 5445-17-0, Methyl 2-bromopropionate, also known as Methyl 2-bromopropionate, is a useful research compound. Its molecular formula is C4H7BrO2 and its molecular weight is 167 g/mol. The purity is usually 95%.
Methyl 2-bromopropionate is used in the synthesis of poly(ADP-Ribose)polymerase inhibitors derived from benzoxazin-3-one. Also used in the synthesis of 5-HT2C antagonists affecting serotonin levels.
Methyl 2-bromopropanoate is a chemical compound that can be synthesized in an asymmetric manner. The reaction of methyl 2-bromopropanoate with hydrochloric acid gives the corresponding carboxylic acid, methyl propanoate, and hydrogen bromide in a 1:1 ratio. It has been shown that methyl 2-bromopropanoate is a potential catalyst for the reduction of chloride to chloride ion via the borohydride reduction method. Methyl 2-bromopropanoate has also been used as a model system for studying halides and copper complexes. Magnetic resonance spectroscopy studies have revealed that this chemical compound has a high redox potential and kinetic properties., 5445-17-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Dehydrobromination, Grignard reactions, reductive coupling, Wittig reaction, and several nucleophilic substitution reactions are some of the principal reactions which involve organic bromides. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Organic compounds having carbon bonded to bromine are called organic bromides. Product Details of C7H8BrN.

Fan, Jiali;Wei, Qiancheng;Zhu, Ershu;Gao, Jing;Cheng, Xiamin;Lu, Yongna;Loh, Teck-Peng research published 《 Visible light-induced mono-bromination of arenes with BrCCl₃》, the research content is summarized as follows. A highly efficient and regioselective bromination of electron-rich arenes and heteroarenes using com. available BrCCl₃ as a “Br” source has been developed. The reaction was performed in air under mild conditions with photocatalyst Ru(bpy)₃Cl₂·6H₂O, avoiding the usage of strong acids and strong oxidants. Mono-brominated products were obtained with medium to excellent yields (up to 94%). This strategy has shown good compatibility and high para-selectivity, which will facilitate the complicated synthesis.

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Product Details of C7H8BrN

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organobromine compounds, also called organobromides, are organic compounds that contain carbon bonded to bromine. 70-23-5, formula is C5H7BrO3, The most pervasive is the naturally produced bromomethane. Quality Control of 70-23-5

Fan, Tingting;Guo, Weikai;Shao, Ting;Zhou, Wenbo;Hu, Pan;Liu, Mingyao;Chen, Yihua;Yi, Zhengfang research published 《 Design, synthesis and evaluation of phenylthiazole and phenylthiophene pyrimidindiamine derivatives targeting the bacterial membrane》, the research content is summarized as follows. A series of phenylthiazole and phenylthiophene pyrimidindiamine derivatives l [R¹ = ethylamino, propylamino, butylamino, pyrrolidino; R² = H, OMe, F, Cl, Br, etc.] were designed and synthesized by modifying the hit compound (N²-isobutyl-N4-((4-methyl-2-phenylthiazol-5-yl)methyl) pyrimidine-2,4-diamine) and their antibacterial activities were evaluated both in-vitro and in-vivo was reported. Among the tested compounds, compound I [R¹ = isobutylamino; R² = 3-bromo] displayed the best antibacterial activities, which was not only capable of inhibiting E. coli and S. aureus growth at concentrations as low as 2 and 3μg/mL in-vitro, but also efficacious in a mice model of bacteremia in vivo. Unlike conventional antibiotics, compound I [R¹ = isobutylamino; R² = 3-bromo] was elucidated to mainly destroy the bacterial cell membrane, with the dissipation of membrane potential and leakage of contents, ultimately leading to cell death. The destruction of cell structure was challenging to induce bacterial resistance, which suggested that compound I [R¹ = isobutylamino; R² = 3-bromo] was a promising alternatives to antibiotics against bacteria.

Quality Control of 70-23-5, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 6911-87-1, formula is C7H8BrN, Name is 4-Bromo-N-methylaniline. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Computed Properties of 6911-87-1.

Fan, Xu;Liu, Hui;Ma, Shidi;Wang, Feng;Yang, Jinhui;Li, Dianjun research published 《 Visible light-induced PPh₂Cy/CsI-promoted cascade radical decarboxylative/cyclization of redox-active esters with acrylamides》, the research content is summarized as follows. A visible-light-induced PPh₂Cy/CsI-promoted tandem radical decarboxylative/alkylarylation of alkyl substituted redox-active esters I (R = t-Bu, cyclohexyl, cyclopentyl, etc.) and N-acrylamides 2-R⁵-3-R⁴-4-R²-5-R³C₆HN(R¹)C(O)C(=CH₂)CH₃ (R¹ = H, Me, Ph, etc.; R² = H, Cl, Br, Me; R³ = H, Me; R⁴ = H, Me; R⁵ = H, Cl, Me, F; R⁴R⁵ = -CH=CH-CH=CH-) or N-methyl-N-(2-methylprop-2-enoyl)benzamides 2-R⁹-3-R⁸-4-R⁷-5-R⁶C₆HC(O)N(Me)C(O)C(=CH₂)Me (R⁶ = H, Me; R⁷ = H, Cl, F, MeO; R⁸ = H, Me; R⁹ = H; R⁸R⁹ = -CH=CH-CH=CH-) to generate 3,3-dialkyl substituted oxindoles II and isoquinoline-1,3-diones derivatives III was developed under metal-free conditions. This transformation provides an alternative and mild method for the synthesis of highly functionalized five- 3,3-dialkyl substituted oxindoles and isoquinoline-1,3-diones derivatives

6911-87-1, 4-Bromo-N-methylaniline is a aniline based compound known to exhibit mutagenic properties.
4-Bromo-N-methylaniline is a useful research compound. Its molecular formula is C7H8BrN and its molecular weight is 186.05 g/mol. The purity is usually 95%.
4-Bromophenylmethylamine is an organic compound that has anti-inflammatory properties and is used as a pharmaceutical. It belongs to the group of amines. The hydrolysis of 4-bromophenylmethylamine by hydrochloric acid produces phenol and bromamine (NHBr). The reaction system can be used to synthesize a number of compounds, including anilines, benzofurans, and other aromatic compounds. 4-Bromophenylmethylamine reacts with muscle tissue in a similar manner as acetaminophen does. This drug also has been shown to have significant effects on the energy metabolism in the muscles of rats that are given carbon source., Computed Properties of 6911-87-1

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic compounds having carbon bonded to bromine are called organic bromides. 70-23-5, formula is C5H7BrO3, Name is Ethyl 3-bromo-2-oxopropanoate. Depending on the type of carbon to which the bromine is bonded, organic bromide could be alkyl, alkenyl, alkynyl, or aryl. Recommanded Product: Ethyl 3-bromo-2-oxopropanoate.

Fang, Lincheng;Hu, Zhaoxue;Yang, Yifei;Chen, Pan;Zhou, Jinpei;Zhang, Huibin research published 《 Discovery of 3,5-dimethylisoxazole derivatives as novel, potent inhibitors for bromodomain and extraterminal domain (BET) family》, the research content is summarized as follows. Bromodomain and extra-terminal (BET) is a promising therapeutic target for various hematol. cancers. We used the BRD4 inhibitor compound 13 (I) as a lead compound to develop a variety of compounds, and we introduced diverse groups into the position of the compound 13 orienting toward the ZA channel. A series of compounds bearing triazolopyridazine motif exhibited remarkable BRD4 protein inhibitory activities. Among them, compound 39 (II) inhibited BRD4(BD1) protein with an IC₅₀ of 0.003μM which was superior to lead compound 13. Meanwhile, compound 39 possess activity, IC₅₀ = 2.1μM, in antiproliferation activity against U266 cancer cells. On the other hand, compound 39 could arrest tumor cells into the G0/G1 phase and induce apoptosis, which was consistent with its results in inhibiting cell proliferation. Biol. and biochem. data suggest that BRD4 protein might be a therapeutic target and that compound 39 is an excellent lead compound for further development.

Recommanded Product: Ethyl 3-bromo-2-oxopropanoate, Ethyl bromopyruvate molecular formula is C5H7BrO3 and its molecular weight is 195.01 g/mol. The purity is usually 95%.

Ethyl bromopyruvate is used in a synthesis of thioxothiazolidines from carbon disulfide and primary amines.

Ethyl bromopyruvate is a chemical inhibitor that inhibits the enzyme pyruvate dehydrogenase, which is responsible for the conversion of pyruvic acid to acetyl-CoA. This inhibition leads to a decrease in ATP levels and can cause metabolic disorders. Ethyl bromopyruvate is used as an anthelmintic drug and in asymmetric synthesis. It is also used in the synthesis of thiostrepton, an antibiotic that has been shown to have antimicrobial activity against Gram-positive bacteria, including Staphylococcus aureus and Streptococcus pneumoniae., 70-23-5.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Organic bromides such as alkyl bromides are used as fumigants in agriculture to control insects. 4224-70-8, formula is C6H11BrO2, Name is 6-Bromohexanoic acid. Ethylene bromide is one of the commercially important organic bromides which are the component of leaded gasoline. Electric Literature of 4224-70-8.

Fang, Xiong;Meng, Qian;Zhang, Huijun;Fang, Xiao;Huang, Lina S.;Zhang, Xingquan;Schooley, Robert T.;Ciechanover, Aaron;An, Jing;Xu, Yan;Huang, Ziwei research published 《 A fragment integrational approach to GPCR inhibition: Identification of a high affinity small molecule CXCR4 antagonist》, the research content is summarized as follows. Here, employed a fragment integrational approached, designed and synthesized a new and potent small mol. CXCR4 antagonist (named as HF51116 I), as well as a fluorescent (FITC)-labeled HF51116 I (FITC-HF51116 I). I exhibited very high CXCR4 binding affinity with IC₅₀ of 12 nM in competitive binding with a CXCR4 specific antibody 12G5, which was comparable to the wild type chemokines or synthetic peptides of much larger mol. sizes. Direct binding measurement using FITC-HF51116 I further revealed the compound’s high CXCR4 affinity. HF51116 I strongly antagonized SDF-1α-induced cell migration, calcium mobilization, and CXCR4 internalization. Furthermore, HF51116 I inhibited HIV-1 infection via CXCR4, demonstrating its antiviral therapeutic potential. The mechanism of HF51116 I-CXCR4 interaction was analyzed by site-directed mutagenesis and mol. modeling which suggested that the compound recognized the minor and major subpockets of CXCR4. Its binding to CXCR4 was found to block G protein-dependent downstream signal pathways as detected by luciferase reporter assays. With its potent bioactivities and asym. structure amenable to chem. diversification, HF51116 I may serve as a prototype for developing a new class of CXCR4-targeted therapeutics and proof of the concept of similar strategies for studying other GPCRs.

Electric Literature of 4224-70-8, 6-bromohexanoic acid is an organobromine compound comprising hexanoic acid having a bromo substituent at the 6-position. It derives from a hexanoic acid.
6-Bromohexanoic acid is a useful research compound. Its molecular formula is C6H11BrO2 and its molecular weight is 195.05 g/mol. The purity is usually 95%.
6-Bromohexanoic acid is useful for the preparation of anti-CTLA4 compounds as antitumor agents.
6-Bromohexanoic acid is a fatty acid that has been shown to be an effective agent for the treatment of cancer. It is used in gene therapy to inhibit the growth of cancer cells by binding to and then activating transcription factors. 6-Bromohexanoic acid can also be used as a chemotherapeutic agent and has been shown to cause apoptosis in monoclonal antibody-treated cells. 6-Bromohexanoic acid has pharmacokinetic properties that are similar to those of other fatty acids. The reaction solution was found to have high chemical stability, which may be due to the presence of nitrogen atoms. This reaction solution was found to adsorb onto the surface of monoclonal antibodies and cell culture, altering their properties., 4224-70-8.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

One prominent application of synthetic organobromine compounds is the use of polybrominated diphenyl ethers as fire-retardants, and in fact fire-retardant manufacture is currently the major industrial use of the element bromine. 1575-37-7, formula is C6H7BrN2, Name is 4-Bromobenzene-1,2-diamine, Quality Control of 1575-37-7

Fasiuddin, G. S.;Liakath Ali Khan, F.;Sakthivel, S.;Muthu, S.;Irfan, Ahmad research published 《 Synthesis, Spectroscopic, Molecular Docking and inhibitory activity of 6-Bromo-2-(4-chlorophenyl)-1H-benzimidazole- a DFT approach》, the research content is summarized as follows. A novel compound 6-bromo-2-(4-chlorophenyl)-1H-benzimidazole was synthesized to treat antimicrobial infections and characterized by FT-IR, FT-Raman, 1H-NMR, UV-Vis. The stable conformer and structural optimization were carried out using the DFT-B3LYP (6-311 ++ G (d, p)) method in Gaussian 16 W. FT-IR and FT-Raman exptl. and theor. wavenumbers with the complete vibrational assignment were reported. NMR of 1H -13C and UV-Vis is calculated at different solvents using the IEF-PCM method. The conductivity, reactivity and stability of the title compound are determined by HOMO-LUMO values. The antibacterial activity was tested against S. aureus and A. niger to indicate a significant zone of inhibition than the reference drug ciprofloxacin at the concentration of 25μg/mL, and protein and ligand interaction site in docking was determined by MEP. Finally, the mol. docking between the title and the reference compound ligand with the A. niger / 3EQA was studied and compared the binding energy of the compound at the active sites.

1575-37-7, 4-Bromo-1,2-diaminobenzene can be obtained from 1,2-diaminobenzene via acetylation followed by bromination and alkaline hydrolysis.
4-Bromobenzene-1,2-diamine, also known as 4-Bromobenzene-1,2-diamine, is a useful research compound. Its molecular formula is C6H7BrN2 and its molecular weight is 187.04 g/mol. The purity is usually 95%.
4-Bromo-1,2-diaminobenzene is a dye that is used in diagnostic
procedures to detect the presence of amide groups. 4-Bromo-1,2-diaminobenzene can be used as an inhibitor for cationic polymerization reactions. It also has tuberculostatic activity and inhibits the growth of Mycobacterium tuberculosis. This compound reacts with aniline to form a benzimidazole derivative that contains a reactive amine group. The reaction between this amine group and different electrophiles generates benzimidazole compounds with different properties that are useful in nucleophilic attack reactions. The reaction between 4-bromo-1,2-diaminobenzene and methyl ethyl sulfide produces a luminescent probe that can be used to detect hydrogen bonds., Quality Control of 1575-37-7

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary