Tag: M.W=150-200

Schmitt, Tanja; Bourelle, Sean; Tye, Nathaniel; Soavi, Giancarlo; Bond, Andrew D.; Feldmann, Sascha; Traore, Boubacar; Katan, Claudine; Even, Jacky; Dutton, Sian E.; Deschler, Felix published the artcile< Control of Crystal Symmetry Breaking with Halogen-Substituted Benzylammonium in Layered Hybrid Metal-Halide Perovskites>, Name: 4-Bromobenzylamine, the main research area is crystal symmetry breaking halobenzylammonium lead iodide layered hybrid perovskite.

Layered hybrid metal-halide perovskites with noncentrosym. crystal structure are predicted to show spin-selective band splitting from Rashba effects. Thus, fabrication of metal-halide perovskites with defined crystal symmetry is desired to control the spin-splitting in their electronic states. Here, the authors report the influence of halogen para-substituents on the crystal structure of benzylammonium lead iodide perovskites (4-XC6H4CH2NH3)2PbI4 (X = H, F, Cl, Br). Using x-ray diffraction and 2nd-harmonic generation, the authors study structure and symmetry of single-crystal and thin-film samples. The authors report that introduction of a halogen atom lowers the crystal symmetry such that the Cl- and Br-substituted structures are noncentrosym. The differences can be attributed to the nature of the intermol. interactions between the organic mols. The authors calculate electronic band structures and find good control of Rashba splittings. The results present a facile approach to tailor hybrid layered metal halide perovskites with potential for spintronic and nonlinear optical applications.

Journal of the American Chemical Society published new progress about Band structure. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Name: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Miguel-Casan, Eugenia; Andres-Garcia, Eduardo; Calbo, Joaquin; Gimenez-Marques, Monica; Minguez Espallargas, Guillermo published the artcile< Selective CO2 Sorption Using Compartmentalized Coordination Polymers with Discrete Voids**>, Quality Control of 3959-07-7, the main research area is coordination polymer void carbon dioxide sorption; CO2; gas separation; metal-organic frameworks; voids.

Carbon capture and storage with porous materials is one of the most promising technologies to minimize CO2 release into the atm. Here, we report a family of compartmentalized coordination polymers (CCPs) capable of capturing gas mols. in a selective manner based on two novel tetrazole-based ligands. Crystal structures have been modelled theor. under the D. Functional Theory (DFT) revealing the presence of discrete voids of 380 Å3. Single gas adsorption isotherms of N2, CH4 and CO2 have been measured, obtaining a loading capacity of 0.6, 1.7 and 2.2 mols./void at 10 bar and at 298 K for the best performing material. Moreover, they present excellent selectivity and regenerability for CO2 in mixtures with CH4 and N2 in comparison with other reported materials, as evidenced by dynamic breakthrough gas experiments These frameworks are therefore great candidates for separation of gas mixtures in the chem. engineering industry.

Chemistry – A European Journal published new progress about Adsorption enthalpy, isosteric. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Yeh, Chien-Hung; Chen, Wei-Chen; Gandeepan, Parthasarathy; Hong, Ya-Chun; Shih, Cheng-Hung; Cheng, Chien-Hong published the artcile< RhIII-catalyzed dual directing group assisted sterically hindered C-H bond activation: a unique route to meta and ortho substituted benzofurans>, Synthetic Route of 188813-04-9, the main research area is internal alkyne hydroxyphenyloxime ether regioselective CH activation heterocyclization rhodium; benzofuran regioselective directing group assisted preparation mol crystal structure; rhodium regioselective sterically hindered CH activation heterocyclization catalyst.

A new strategy for the synthesis of highly substituted benzofurans, e.g., I (X-rays single crystal structure shown), from meta-substituted hydroxybenzenes and alkynes via a rhodium(III)-catalyzed activation of a sterically hindered C-H bond is demonstrated. A possible mechanism involving dual directing group assisted ortho C-H bond activation is proposed.

Organic & Biomolecular Chemistry published new progress about Alkynes, internal Role: RCT (Reactant), RACT (Reactant or Reagent). 188813-04-9 belongs to class bromides-buliding-blocks, and the molecular formula is C8H7BrO, Synthetic Route of 188813-04-9.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Zou, Wen; Liu, Xiao-Hui; Xue, Can; Zhou, Xian-Tai; Yu, Hai-Yang; Fan, Ping; Ji, Hong-Bing published the artcile< Enhancement of the visible-light absorption and charge mobility in a zinc porphyrin polymer/g-C3N4 heterojunction for promoting the oxidative coupling of amines>, Category: bromides-buliding-blocks, the main research area is zinc porphyrin microporous polymer photooxidation photocatalysis heterojunction.

Graphitic carbon nitride (g C3N4, CN) has been widely used as a photocatalyst due to its high stability and suitable band gap. However, its further development is limited due to inefficient light harvesting and rapid recombination of photogenerated carriers. In this study, a visible-light-responsive zinc porphyrin (ZnP)/CN heterojunction photocatalyst was synthesized by the combination of CN and a zinc-porphyrin-conjugated microporous polymer (ZnP-CMP). ZnP/CN exhibited excellent photocatalytic activity for the oxidative coupling of amines to imines under visible-light irradiation The efficiency of the as-developed photocatalyst was 25 times greater than that of CN and about 2 times greater than that of ZnP-CMP. The significantly enhanced catalytic efficiency was attributed to the promotion of visible-light harvesting and photogenerated charge mobility via the introduction of ZnP-CMP. The ZnP/CN heterojunction photocatalyst also exhibited excellent broad substrate scope, stability, and reusability.

Applied Catalysis, B: Environmental published new progress about Crystal vacancies (oxygen). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Category: bromides-buliding-blocks.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Schumann, Andre; Reiss, Fabian; Jiao, Haijun; Rabeah, Jabor; Siewert, Jan-Erik; Krummenacher, Ivo; Braunschweig, Holger; Hering-Junghans, Christian published the artcile< A selective route to aryl-triphosphiranes and their titanocene-induced fragmentation>, Electric Literature of 576-83-0, the main research area is aryl triphosphirane titanocene fragmentation preparation reactivity mechanism; crystal structure mol optimized triphosphirane titanocene diphosphene preparation.

Triphosphiranes are three-membered phosphorus cycles and their fundamental reactivity has been studied in recent decades. We recently developed a high-yielding, selective synthesis for various aryl-substituted triphosphiranes. Variation of the reaction conditions in combination with theor. studies helped to rationalize the formation of these homoleptic phosphorus ring systems and highly reactive intermediates could be isolated. In addition we showed that a titanocene synthon [Cp2Ti(btmsa)] facilitates the selective conversion of these triphosphiranes into titanocene diphosphene complexes. This unexpected reactivity mode was further studied theor. and exptl. evidence is presented for the proposed reaction mechanism.

Chemical Science published new progress about Crystal structure. 576-83-0 belongs to class bromides-buliding-blocks, and the molecular formula is C9H11Br, Electric Literature of 576-83-0.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Ke, Da; Zhou, Shaodong published the artcile< General Construction of Amine via Reduction of N=X (X = C, O, H) Bonds Mediated by Supported Nickel Boride Nanoclusters>, Quality Control of 3959-07-7, the main research area is primary amine preparation; nitrile reduction nickel boride nanocluster catalyst; nitro compound hydrogenation nickel boride nanocluster catalyst; benzaldehyde reduction nickel boride nanocluster catalyst; hydrogenation; nickel boride; primary amine; reductive amination.

Herein, an efficient catalyst for the general construction of amine mediated by nickel boride nanoclusters supported by a TS-1 mol. sieve was reported. Efficient production of amines RCH2NH2 (R = 5-aminopentyl, cyclohexyl, Ph, pyridin-2-yl, etc.), 3-R1-4-R2-C6H3NH2 (R1 = H, F; R2 = H, F, Cl, Me, Br, OH, NH2) was achieved via catalytic hydrogenation of N=X (X = C, O, H) bonds. In addition, the catalyst maintains excellent performance upon recycling. Compared with the previous reports, the high activity, simple preparation and reusability of the Ni-B catalyst in this work make it promising for industrial application in the production of amines.

International Journal of Molecular Sciences published new progress about Benzaldehydes Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Quality Control of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Long, Solida; Loureiro, Joana B.; Carvalho, Carla; Gales, Lu Is; Saraiva, Lucilia; Pinto, Madalena M. M.; Puthongking, Ploenthip; Sousa, Emilia published the artcile< Semi-synthesis of small molecules of aminocarbazoles: tumor growth inhibition and potential impact on p53>, Recommanded Product: 4-Bromobenzylamine, the main research area is aminocarbazole derivative preparation antitumor p53 activator; alkaloids; aminocarbazoles; heptaphylline; mutant; p53; tumor.

The tumor cell growth inhibitory activity of aminocarbazole derivatives, I [R = H, OMe; R1 = H, CH2CHC(Me)2; R2 = NH(CH2)3N(Me)2, pipridin-1-yl, 4-ClC6H4NH, etc.] as well as their potential activation of p53 was reported. Compounds I was synthesized from naturally-occurring carbazoles II [R3 = H, OMe; R4 = H, CH2CHC(Me)2] with amine precursors and isolated from Clausena harmandiana, using a reductive amination protocol. Compounds I and II were evaluated for their potential effect on wild-type and mutant p53 activity using a yeast screening assay and on human tumor cell lines. Naturally-occurring carbazoles II showed the most potent growth inhibitory effects on wild-type p53-expressing cells, being heptaphylline II [R3 = H; R4 = CH2CHC(Me)2] the most promising in all the investigated cell lines. However, compound II [R3 = H; R4 = CH2CHC(Me)2] also showed growth inhibition against non-tumor cells. Conversely, semi-synthetic aminocarbazole I [R = H; R1 = CH2CHC(Me)2; R2 = 4-FC6H4NH] showed an interesting growth inhibitory activity in tumor cells expressing both wild-type and mutant p53, exhibiting low growth inhibition on non-tumor cells. The yeast assay showed a potential reactivation of mutant p53 by heptaphylline derivatives, including compound I [R = H; R1 = CH2CHC(Me)2; R2 = 4-FC6H4NH].

Molecules published new progress about Amines Role: PAC (Pharmacological Activity), PRP (Properties), RCT (Reactant), SPN (Synthetic Preparation), THU (Therapeutic Use), BIOL (Biological Study), RACT (Reactant or Reagent), PREP (Preparation), USES (Uses). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Recommanded Product: 4-Bromobenzylamine.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Huang, Wanqiao; Zhang, Ruzhong; Zhang, Ruxue; Yu, Jianxin; Wang, Mang published the artcile< Radical hydrotrifluoromethylation of ynamides: a route toward β-CF3 enamides>, Synthetic Route of 3959-07-7, the main research area is aryl trifluoromethyl amine preparation; trifluoromethyl enamide preparation diastereoselective deprotection reduction reaction; ynamide chlorophenyl trifluoromethyliodane radical hydrotrifluoromethylation reaction.

Radical hydrotrifluoromethylation of ynamides RNR2CCR1 (R = Ph, 3-chlorophenyl, benzodioxol-5-yl, etc.; R1 = H, cyclopropyl, Ph, etc.; R2 = Boc, Ac, Cbz) to provide an alternative route toward (E)-β-CF3 enamides RNR2CH=C(CF3)R1 was reported. By using PhICF3Cl as the CF3 reagent and DMF as the H-donor, the reaction occurred smoothly in the presence of NaH at room temperature Further reduction of the resulting β-CF3 enamides efficiently delivered β-CF3 amines RNHCH2CH(CF3)R1. Gram-scale synthesis was conducted to demonstrate the practicability of the method.

Organic Chemistry Frontiers published new progress about Diastereoselective synthesis. 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Synthetic Route of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Nazarahari, Maryam; Azizian, Javad published the artcile< FeCl2-PPh3 as an efficient catalytic system for the acceptorless dehydrogenation of amines into imines>, Product Details of C7H8BrN, the main research area is benzylamine iron chloride triphenylphosphine catalyst diastereoselective dehydrogenative coupling; phenylmethanimine preparation.

A novel and simple catalytic system including FeCl2, PPh3 and potassium tert-butoxide were employed for the synthesis of imines from amines. In order to prove the catalytic acceptorless dehydrogenation pathway for this transformation, the liberated H2 gas was detected by NMR spectroscopy. By utilizing this protocol, a variety of arylamines were used successfully for the preparation of corresponding imines in good to excellent yields (on a 1 mmol scale, 73-91% yield for homocoupling, 71 and 91% for heterocoupling).

Chemical Papers published new progress about Aralkyl amines Role: RCT (Reactant), RACT (Reactant or Reagent). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Product Details of C7H8BrN.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary

Thorve, Pradip Ramdas; Maji, Biplab published the artcile< Aerobic primary and secondary amine oxidation cascade by a copper amine oxidase inspired catalyst>, Electric Literature of 3959-07-7, the main research area is quinazolinone preparation kinetic mechanistic study; amine aminobenzamide cascade aerobic oxidative coupling copper catalyst.

Herein, a bioinspired catalytic system for the one-pot cascade oxidation of a native primary amine and an in situ generated non-native secondary amine is reported. The catalyst consists of an o-quinone cofactor phd (1,10-phenanthroline-5,6-dione) and a copper ion and operates under ambient air conditions. Quinazolin-4(3H)-ones, which are common pharmacophores present in numerous pharmaceuticals and bioactive compounds, were synthesized in high yields. A detailed kinetic and mechanistic study elucidates the role of the catalyst in the multi-step oxidative cascade reaction.

Catalysis Science & Technology published new progress about Benzamides Role: RCT (Reactant), RACT (Reactant or Reagent) (amino). 3959-07-7 belongs to class bromides-buliding-blocks, and the molecular formula is C7H8BrN, Electric Literature of 3959-07-7.

Referemce:
Bromide – Wikipedia,
bromide – Wiktionary